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Diagnostic term associations

Self-Reported Statistics (SRS)

Sickle cell disease
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs3135753 lBF = 1.18304   Chr10 : 123,280,658
0.246 0.753 0.000
rs79858930 lBF = 1.3229   Chr10 : 83,047,434
0.179 0.821 0.000
rs12413578 lBF = 44.9786   Chr10 : 9,049,253
0.000 0.950 0.049
rs4746853 lBF = 0.398543   Chr10 : 64,181,219
0.026 0.974 0.000
rs1801239 lBF = 0.337436   Chr10 : 16,919,052
0.000 0.986 0.014
rs157079 lBF = 0.854686   Chr10 : 106,058,778
0.013 0.987 0.000
rs192665745 lBF = 0.12204   Chr10 : 26,627,381
0.011 0.988 0.000
rs7358151 lBF = 0.214149   Chr10 : 28,017,572
0.011 0.989 0.000
rs11254363 lBF = 0.65019   Chr10 : 17,130,693
0.000 0.994 0.006
rs2944542 lBF = 2.84414   Chr10 : 64,369,999
0.005 0.994 0.000
rs12251514 lBF = 0.0315432   Chr10 : 52,259,794
0.005 0.995 0.000
rs791590 lBF = 4.67185   Chr10 : 6,090,322
0.000 0.995 0.005
rs12722489 lBF = 4.78015   Chr10 : 6,102,012
0.000 0.995 0.005
rs11000019 lBF = 0.0553572   Chr10 : 73,591,530
0.005 0.995 0.000
rs12251332 lBF = 0.0602989   Chr10 : 67,966,574
0.004 0.995 0.000
rs74606055 lBF = 0.128544   Chr10 : 131,932,578
0.004 0.995 0.000
rs2487928 lBF = -0.0319229   Chr10 : 30,323,892
0.000 0.995 0.004
rs61839660 lBF = 11.4863   Chr10 : 6,094,697
0.004 0.996 0.001
rs116369954 lBF = 0.808434   Chr10 : 114,793,572
0.004 0.996 0.000
rs10752212 lBF = -0.158614   Chr10 : 10,917,121
0.004 0.996 0.000
rs1801222 lBF = 0.626794   Chr10 : 17,156,151
0.000 0.996 0.004
rs12722515 lBF = 3.9144   Chr10 : 6,081,230
0.000 0.996 0.004
rs2505083 lBF = -0.0659218   Chr10 : 30,335,122
0.000 0.996 0.004
rs11255615 lBF = 0.0394299   Chr10 : 8,324,889
0.003 0.997 0.000
rs7897194 lBF = 0.0148696   Chr10 : 20,792,334
0.003 0.997 0.000
rs12722561 lBF = 4.0736   Chr10 : 6,069,893
0.000 0.997 0.003
rs12722495 lBF = 11.7289   Chr10 : 6,097,283
0.003 0.997 0.001
rs12251307 lBF = 8.78578   Chr10 : 6,123,495
0.003 0.997 0.000
rs3739998 lBF = -0.148591   Chr10 : 30,316,072
0.000 0.997 0.002
rs77329626 lBF = 0.133897   Chr10 : 61,664,195
0.002 0.998 0.000
rs190780914 lBF = 0.0289979   Chr10 : 84,949,895
0.000 0.998 0.002
rs41289279 lBF = -0.0546282   Chr10 : 988,262
0.002 0.998 0.000
rs12570188 lBF = 0.0215551   Chr10 : 100,855,702
0.002 0.998 0.000
rs1679568 lBF = -0.10634   Chr10 : 117,817,551
0.002 0.998 0.000
rs12243326 lBF = 24.4805   Chr10 : 114,788,815
0.002 0.998 0.000
rs35632171 lBF = 1.83027   Chr10 : 65,109,502
0.002 0.998 0.000
rs9333182 lBF = -0.0992148   Chr10 : 15,619,054
0.002 0.998 0.000
rs10905716 lBF = 8.16145   Chr10 : 6,114,010
0.000 0.998 0.002
rs139479025 lBF = 0.0127221   Chr10 : 71,880,301
0.002 0.998 0.000
rs75941567 lBF = 0.0660704   Chr10 : 65,406,487
0.002 0.998 0.000
rs706778 lBF = 15.8763   Chr10 : 6,098,949
0.002 0.998 0.000
rs6602364 lBF = 3.11849   Chr10 : 6,038,853
0.000 0.998 0.002
rs72786098 lBF = 0.055151   Chr10 : 18,729,855
0.000 0.998 0.001
rs10764775 lBF = -0.158055   Chr10 : 130,233,808
0.002 0.998 0.000
rs706778 lBF = 15.7804   Chr10 : 6,098,949
0.001 0.998 0.000
rs16928529 lBF = 0.0306678   Chr10 : 72,982,985
0.001 0.998 0.000
rs190509410 lBF = -0.00132675   Chr10 : 63,626,494
0.001 0.998 0.000
rs4468302 lBF = 0.0378907   Chr10 : 60,164,572
0.001 0.998 0.001
rs17497526 lBF = -0.0686921   Chr10 : 71,580,120
0.000 0.998 0.001
rs56161216 lBF = 0.0070472   Chr10 : 13,688,798
0.001 0.998 0.000
rs12249377 lBF = -0.0300521   Chr10 : 92,592,956
0.000 0.998 0.001
rs4918918 lBF = -0.157191   Chr10 : 97,122,241
0.000 0.999 0.001
rs17854135 lBF = 1.83007   Chr10 : 101,667,792
0.001 0.999 0.001
rs71508903 lBF = 27.2185   Chr10 : 63,779,871
0.001 0.999 0.000
rs6602175 lBF = 0.0761411   Chr10 : 17,142,526
0.001 0.999 0.000
rs7098187 lBF = 0.00140433   Chr10 : 15,538,383
0.001 0.999 0.000
rs2986961 lBF = -0.144413   Chr10 : 30,087,359
0.001 0.999 0.000
rs2589559 lBF = 28.8319   Chr10 : 9,061,370
0.001 0.999 0.000
rs10736877 lBF = -0.0374333   Chr10 : 128,373,707
0.000 0.999 0.001
rs10794108 lBF = -0.222224   Chr10 : 128,423,873
0.000 0.999 0.001
rs76934034 lBF = -0.084492   Chr10 : 46,082,985
0.000 0.999 0.001
rs2901286 lBF = 0.0767192   Chr10 : 122,900,623
0.001 0.999 0.000
rs11598874 lBF = -0.0188847   Chr10 : 39,006,198
0.001 0.999 0.000
rs796127 lBF = -0.132842   Chr10 : 31,968,729
0.001 0.999 0.000
rs4838508 lBF = 0.00096585   Chr10 : 50,561,507
0.000 0.999 0.001
rs11001678 lBF = 0.0366983   Chr10 : 77,955,610
0.001 0.999 0.000
rs1148233 lBF = 0.00217451   Chr10 : 31,461,599
0.001 0.999 0.000
rs115882204 lBF = 0.00589499   Chr10 : 28,590,383
0.001 0.999 0.001
rs41322152 lBF = 0.00374427   Chr10 : 72,040,805
0.001 0.999 0.000
rs7921536 lBF = 0.00282557   Chr10 : 105,356,837
0.001 0.999 0.000
rs12573070 lBF = 0.0293604   Chr10 : 15,085,073
0.000 0.999 0.001
rs10995485 lBF = 0.0222444   Chr10 : 65,026,858
0.001 0.999 0.000
rs10998035 lBF = 0.0901149   Chr10 : 70,014,230
0.000 0.999 0.001
rs7092929 lBF = 0.024588   Chr10 : 3,538,794
0.000 0.999 0.001
rs9943451 lBF = 0.0129441   Chr10 : 7,070,570
0.001 0.999 0.000
rs181778161 lBF = 0.0015845   Chr10 : 91,691,500
0.001 0.999 0.000
rs7904655 lBF = 0.00151214   Chr10 : 22,838,726
0.001 0.999 0.000
rs7907139 lBF = -0.0113205   Chr10 : 107,833,640
0.001 0.999 0.000
rs12248541 lBF = 0.00173949   Chr10 : 105,390,343
0.001 0.999 0.000
rs1002442 lBF = -0.110994   Chr10 : 61,803,062
0.001 0.999 0.000
rs11014249 lBF = -0.149609   Chr10 : 25,111,910
0.000 0.999 0.001
rs4751178 lBF = 0.430334   Chr10 : 131,992,245
0.001 0.999 0.000
rs9329300 lBF = 0.0518418   Chr10 : 2,789,594
0.001 0.999 0.000
rs7895372 lBF = 0.0008572   Chr10 : 15,719,621
0.001 0.999 0.000
rs114154155 lBF = 0.00066648   Chr10 : 63,185,662
0.001 0.999 0.000
rs61458523 lBF = 0.0005677   Chr10 : 60,668,571
0.000 0.999 0.001
rs150400940 lBF = 0.00031309   Chr10 : 113,810,429
0.001 0.999 0.000
rs10508343 lBF = 0.00012975   Chr10 : 8,150,713
0.001 0.999 0.000
rs3750716 lBF = 0.0000115   Chr10 : 101,816,863
0.001 0.999 0.000
rs77040403 lBF = 0   Chr10 : 71,640,838
0.001 0.999 0.001
rs188724679 lBF = 0   Chr10 : 135,224,855
0.001 0.999 0.001
rs12263766 lBF = 0   Chr10 : 9,996,990
0.001 0.999 0.001
rs144473309 lBF = 0   Chr10 : 77,129,161
0.001 0.999 0.001
rs115553536 lBF = 0   Chr10 : 31,981,385
0.001 0.999 0.001
rs4750829 lBF = 0   Chr10 : 132,547,261
0.001 0.999 0.001
rs10796051 lBF = 0   Chr10 : 13,310,071
0.001 0.999 0.001
rs190671939 lBF = 0   Chr10 : 134,909,987
0.001 0.999 0.001
rs117260820 lBF = 0   Chr10 : 102,048,643
0.001 0.999 0.001
rs190045766 lBF = 0   Chr10 : 120,643,886
0.001 0.999 0.001
rs181666690 lBF = 0   Chr10 : 28,852,022
0.001 0.999 0.001
rs76409888 lBF = 0   Chr10 : 73,723,956
0.001 0.999 0.001
rs184737911 lBF = 0   Chr10 : 88,431,292
0.001 0.999 0.001
rs78627331 lBF = 0   Chr10 : 94,812,254
0.001 0.999 0.001
rs185636671 lBF = 0   Chr10 : 135,172,794
0.001 0.999 0.001
rs76850691 lBF = 0   Chr10 : 101,157,438
0.001 0.999 0.001
rs185671464 lBF = 0   Chr10 : 54,486,920
0.001 0.999 0.001
rs142973438 lBF = 0   Chr10 : 95,315,999
0.001 0.999 0.001
rs180858466 lBF = 0   Chr10 : 38,761,238
0.001 0.999 0.001
rs114088342 lBF = 0   Chr10 : 35,918,232
0.001 0.999 0.001
rs140682412 lBF = 0   Chr10 : 89,332,706
0.001 0.999 0.001
rs79105493 lBF = 0   Chr10 : 95,475,354
0.001 0.999 0.001
rs12245299 lBF = 0   Chr10 : 55,913,700
0.001 0.999 0.001
rs143988467 lBF = 0   Chr10 : 95,317,394
0.001 0.999 0.001
rs183323229 lBF = 0   Chr10 : 33,168,215
0.001 0.999 0.001
rs182344828 lBF = 0   Chr10 : 54,593,326
0.001 0.999 0.001
rs182554582 lBF = 0   Chr10 : 88,194,959
0.001 0.999 0.001
rs58600253 lBF = 0   Chr10 : 64,507,904
0.001 0.999 0.001
rs7072776 lBF = 0   Chr10 : 22,032,942
0.001 0.999 0.001
rs4586057 lBF = -0.127875   Chr10 : 92,632,899
0.000 0.999 0.001
rs17747401 lBF = 0.103292   Chr10 : 76,400,164
0.001 0.999 0.000
rs12252129 lBF = 0.00007109   Chr10 : 50,103,072
0.000 0.999 0.001
rs146091982 lBF = -0.00014096   Chr10 : 95,659,958
0.000 0.999 0.001
rs384627 lBF = -0.00045705   Chr10 : 119,336,746
0.000 0.999 0.001
rs143362648 lBF = -0.00047122   Chr10 : 21,694,219
0.001 0.999 0.000
rs147729365 lBF = -0.00157561   Chr10 : 12,482,907
0.001 0.999 0.000
rs7078439 lBF = -0.20903   Chr10 : 128,419,984
0.001 0.999 0.000
rs2393895 lBF = 0.446414   Chr10 : 64,338,846
0.001 0.999 0.000
rs4750535 lBF = 0.00059597   Chr10 : 14,633,024
0.001 0.999 0.000
rs12247397 lBF = -0.00025744   Chr10 : 9,363,877
0.000 0.999 0.000
rs1397615 lBF = -0.00032935   Chr10 : 120,966,339
0.000 0.999 0.000
rs2388328 lBF = -0.00047877   Chr10 : 131,234,372
0.001 0.999 0.000
rs192858301 lBF = -0.00070322   Chr10 : 24,071,006
0.001 0.999 0.000
rs11204213 lBF = -0.00076964   Chr10 : 48,388,228
0.001 0.999 0.000
rs4086116 lBF = -0.10741   Chr10 : 96,707,202
0.000 0.999 0.001
rs17625382 lBF = -0.123435   Chr10 : 59,572,708
0.000 0.999 0.001
rs12775535 lBF = 0.280845   Chr10 : 25,918,879
0.001 0.999 0.000
rs11006464 lBF = -0.0308671   Chr10 : 61,146,582
0.001 0.999 0.000
rs11199874 lBF = 10.1859   Chr10 : 123,032,519
0.000 0.999 0.001
rs146173241 lBF = 0.00091902   Chr10 : 118,044,738
0.000 0.999 0.000
rs16926523 lBF = -0.00096896   Chr10 : 26,294,828
0.001 0.999 0.000
rs12261589 lBF = -0.00144901   Chr10 : 79,540,835
0.000 0.999 0.000
rs7905537 lBF = -0.114489   Chr10 : 34,231,275
0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
rs7088203 lBF = 0.0284132   Chr10 : 73,946,588
0.001 0.999 0.000
rs1555804 lBF = -0.00448502   Chr10 : 23,393,066
0.001 0.999 0.000
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0.001 0.999 0.000
rs10788160 lBF = 10.2944   Chr10 : 123,033,549
0.000 0.999 0.001
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0.000 0.999 0.001
rs117841971 lBF = -0.0354099   Chr10 : 80,699,184
0.000 0.999 0.001
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0.000 0.999 0.001
rs17470570 lBF = -0.0850575   Chr10 : 100,580,123
0.001 0.999 0.000
rs2275620 lBF = -0.145064   Chr10 : 96,802,598
0.000 0.999 0.001
rs12220238 lBF = 0.0646618   Chr10 : 75,952,670
0.000 0.999 0.001
rs1320448 lBF = 0.00296142   Chr10 : 105,846,074
0.001 0.999 0.000
rs11199254 lBF = -0.00120086   Chr10 : 122,043,489
0.000 0.999 0.000
rs138071473 lBF = -0.00255128   Chr10 : 13,673,528
0.000 0.999 0.000
rs7070038 lBF = -0.00371241   Chr10 : 59,724,388
0.000 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
rs501120 lBF = 0.125313   Chr10 : 44,753,867
0.000 0.999 0.001
rs2477664 lBF = 0.0254218   Chr10 : 17,875,816
0.001 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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rs10734105 lBF = -0.140076   Chr10 : 133,172,119
0.000 0.999 0.000
rs2274223 lBF = -0.144785   Chr10 : 96,066,341
0.000 0.999 0.000
rs2441755 lBF = -0.145942   Chr10 : 68,165,267
0.000 0.999 0.000
rs11193561 lBF = -0.148088   Chr10 : 109,374,384
0.000 0.999 0.000
rs1360573 lBF = -0.148875   Chr10 : 36,885,921
0.000 0.999 0.000
rs962993 lBF = 54.6039   Chr10 : 9,053,132
0.000 0.999 0.000
rs7903146 lBF = 33.6503   Chr10 : 114,758,349
0.000 0.999 0.000
rs34872471 lBF = 33.6058   Chr10 : 114,754,071
0.000 0.999 0.000
rs11256193 lBF = 6.8509   Chr10 : 9,456,889
0.000 0.999 0.000
rs3740393 lBF = 1.14638   Chr10 : 104,636,655
0.000 0.999 0.000
rs1250540 lBF = 0.809057   Chr10 : 81,036,007
0.000 0.999 0.000
rs10995245 lBF = 0.627291   Chr10 : 64,391,375
0.000 0.999 0.000
rs2223089 lBF = 0.543354   Chr10 : 124,210,160
0.000 0.999 0.000
rs79193624 lBF = 0.407865   Chr10 : 64,000,336
0.000 0.999 0.000
rs11258747 lBF = 0.397943   Chr10 : 6,472,891
0.000 0.999 0.000
rs10994338 lBF = 0.143731   Chr10 : 62,181,128
0.000 0.999 0.000
rs3213056 lBF = 0.142504   Chr10 : 62,548,390
0.000 0.999 0.000
rs10994336 lBF = 0.138609   Chr10 : 62,179,812
0.000 0.999 0.000
rs4387287 lBF = 0.120902   Chr10 : 105,677,897
0.000 0.999 0.000
rs758569 lBF = 0.101619   Chr10 : 119,193,153
0.000 0.999 0.000
rs17770015 lBF = 0.0536963   Chr10 : 115,238,764
0.000 0.999 0.000
rs72831785 lBF = 0.0438168   Chr10 : 110,972,057
0.000 0.999 0.000
rs1625975 lBF = 0.0294697   Chr10 : 73,422,284
0.000 0.999 0.000
rs11006923 lBF = 0.0275523   Chr10 : 28,504,944
0.000 0.999 0.000
rs10904363 lBF = 0.0246215   Chr10 : 4,920,413
0.000 0.999 0.000
rs7919823 lBF = 0.00794176   Chr10 : 22,036,491
0.000 0.999 0.000
rs3923564 lBF = 0.00466235   Chr10 : 81,735,981
0.000 0.999 0.000
rs7903144 lBF = -0.00190123   Chr10 : 22,057,405
0.000 0.999 0.000
rs117256623 lBF = -0.00246165   Chr10 : 123,454,174
0.000 0.999 0.000
rs73338448 lBF = -0.00762369   Chr10 : 99,882,156
0.000 0.999 0.000
rs75473620 lBF = -0.00845855   Chr10 : 96,019,029
0.000 0.999 0.000
rs10994607 lBF = -0.0106928   Chr10 : 62,760,742
0.000 0.999 0.000
rs55812591 lBF = -0.0116819   Chr10 : 134,021,576
0.000 0.999 0.000
rs10508517 lBF = -0.0118635   Chr10 : 16,997,891
0.000 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.