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Diagnostic term associations

Self-Reported Statistics (SRS)

Sickle cell disease
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs45475795 lBF = 11.6242   Chr4 : 123,399,491
0.421 0.579 0.000
rs6844473 lBF = 1.27081   Chr4 : 147,368,219
0.171 0.829 0.000
rs13107325 lBF = 17.3151   Chr4 : 103,188,709
0.111 0.888 0.000
rs13107325 lBF = 16.8696   Chr4 : 103,188,709
0.111 0.889 0.000
rs35518360 lBF = 10.729   Chr4 : 103,146,890
0.095 0.905 0.000
rs13135092 lBF = 16.8388   Chr4 : 103,198,082
0.069 0.931 0.000
rs6822844 lBF = 11.05   Chr4 : 123,509,421
0.000 0.954 0.045
rs13132933 lBF = 4.7421   Chr4 : 123,010,587
0.000 0.956 0.044
rs13119723 lBF = 10.0364   Chr4 : 123,218,313
0.000 0.966 0.034
rs13151961 lBF = 9.08866   Chr4 : 123,115,502
0.000 0.967 0.033
rs6822844 lBF = 11.7849   Chr4 : 123,509,421
0.000 0.967 0.032
rs78428368 lBF = 0.416822   Chr4 : 164,617,481
0.024 0.976 0.000
rs13134336 lBF = 0.102048   Chr4 : 68,270,725
0.015 0.984 0.000
rs55768019 lBF = -0.0349154   Chr4 : 175,027,516
0.013 0.987 0.000
rs34592089 lBF = 4.7869   Chr4 : 102,926,923
0.009 0.987 0.004
rs17074636 lBF = 0.263665   Chr4 : 184,278,131
0.009 0.991 0.000
rs1448284 lBF = 0.126707   Chr4 : 33,079,655
0.000 0.991 0.009
rs6054 lBF = 1.94729   Chr4 : 155,489,608
0.009 0.991 0.001
rs115225351 lBF = 0.196208   Chr4 : 110,732,386
0.008 0.991 0.000
rs62324204 lBF = 1.70572   Chr4 : 123,547,596
0.006 0.994 0.000
rs74964132 lBF = 0.115361   Chr4 : 154,478,742
0.006 0.994 0.000
rs190057637 lBF = 0.0665461   Chr4 : 60,338,268
0.005 0.994 0.000
rs7677281 lBF = 0.392549   Chr4 : 78,341,660
0.005 0.995 0.000
rs17589290 lBF = 0.0733358   Chr4 : 112,923,237
0.004 0.996 0.000
rs1229984 lBF = 11.0476   Chr4 : 100,239,319
0.004 0.996 0.000
rs62341268 lBF = 1.47038   Chr4 : 190,224,770
0.004 0.996 0.000
rs111361850 lBF = 0.0522662   Chr4 : 124,663,356
0.003 0.996 0.000
rs2622604 lBF = 0.0382775   Chr4 : 89,078,924
0.003 0.996 0.000
rs141853578 lBF = 0.0334186   Chr4 : 110,685,820
0.003 0.997 0.000
rs17022027 lBF = -0.0577457   Chr4 : 95,614,278
0.003 0.997 0.000
rs77626873 lBF = 0.115956   Chr4 : 146,075,220
0.003 0.997 0.000
rs1229984 lBF = 11.331   Chr4 : 100,239,319
0.000 0.997 0.003
rs6815464 lBF = 0.0324173   Chr4 : 1,309,901
0.002 0.997 0.000
rs115650236 lBF = -0.0456015   Chr4 : 59,668,829
0.000 0.997 0.002
rs6856328 lBF = 0.0337775   Chr4 : 62,437,318
0.002 0.998 0.000
rs11727767 lBF = -0.0508003   Chr4 : 174,602,048
0.002 0.998 0.000
rs114326390 lBF = 0.0215223   Chr4 : 30,704,527
0.002 0.998 0.000
rs17291045 lBF = 0.111404   Chr4 : 161,506,897
0.001 0.998 0.001
rs28875200 lBF = 0.00999419   Chr4 : 90,027,928
0.002 0.998 0.000
rs1054627 lBF = 2.49801   Chr4 : 88,732,692
0.002 0.998 0.000
rs1399212 lBF = 0.0208592   Chr4 : 128,523,964
0.000 0.998 0.002
rs16990641 lBF = 0.0136295   Chr4 : 35,009,208
0.001 0.998 0.000
rs13119516 lBF = -0.023435   Chr4 : 102,841,605
0.000 0.998 0.002
rs189578969 lBF = 0.00538003   Chr4 : 46,732,290
0.001 0.998 0.000
rs7666831 lBF = 0.00962129   Chr4 : 93,321,027
0.001 0.998 0.000
rs76049629 lBF = -0.179813   Chr4 : 94,759,035
0.002 0.998 0.000
rs13107461 lBF = 0.141012   Chr4 : 68,978,569
0.001 0.998 0.000
rs16871289 lBF = 0.02048   Chr4 : 21,511,383
0.000 0.998 0.001
rs77556290 lBF = 0.0285716   Chr4 : 105,880,750
0.001 0.998 0.000
rs1117139 lBF = 0.0704826   Chr4 : 160,589,307
0.001 0.998 0.000
rs116409347 lBF = 0.0488065   Chr4 : 75,146,481
0.001 0.998 0.000
rs116557628 lBF = -0.0281096   Chr4 : 151,340,224
0.001 0.998 0.000
rs13152134 lBF = -0.00603442   Chr4 : 156,465,403
0.001 0.998 0.000
rs6534347 lBF = 7.14692   Chr4 : 123,198,435
0.001 0.999 0.000
rs9994162 lBF = -0.0187883   Chr4 : 110,715,473
0.001 0.999 0.000
rs6818964 lBF = 0.114519   Chr4 : 73,970,464
0.000 0.999 0.001
rs114333031 lBF = -0.0390923   Chr4 : 54,774,510
0.000 0.999 0.001
rs116780164 lBF = -0.00037075   Chr4 : 15,084,981
0.000 0.999 0.001
rs17638464 lBF = -0.0184771   Chr4 : 162,602,209
0.001 0.999 0.000
rs294777 lBF = 0.00930357   Chr4 : 69,682,471
0.000 0.999 0.001
rs116531279 lBF = 0.270765   Chr4 : 31,427,147
0.001 0.999 0.000
rs3805322 lBF = 0.00731983   Chr4 : 100,056,998
0.001 0.999 0.000
rs342958 lBF = 0.00568269   Chr4 : 86,280,638
0.001 0.999 0.000
rs11935423 lBF = -0.0983059   Chr4 : 100,477,462
0.000 0.999 0.001
rs2725220 lBF = 0.0070775   Chr4 : 88,959,922
0.001 0.999 0.000
rs6818288 lBF = 0.0447329   Chr4 : 30,068,213
0.000 0.999 0.001
rs193022444 lBF = -0.0000629   Chr4 : 46,769,376
0.001 0.999 0.000
rs77388539 lBF = -0.0215608   Chr4 : 167,556,784
0.001 0.999 0.000
rs1115363 lBF = 0.00715814   Chr4 : 67,073,143
0.001 0.999 0.000
rs72909131 lBF = 0.00425145   Chr4 : 83,512,841
0.001 0.999 0.000
rs77184804 lBF = 0.0535961   Chr4 : 171,536,492
0.001 0.999 0.000
rs11931074 lBF = -0.0342272   Chr4 : 90,639,515
0.000 0.999 0.001
rs12507634 lBF = -0.152845   Chr4 : 175,071,602
0.001 0.999 0.000
rs6812193 lBF = -0.155412   Chr4 : 77,198,986
0.000 0.999 0.001
rs4470583 lBF = 0.00122062   Chr4 : 162,250,932
0.001 0.999 0.000
rs146799867 lBF = 0.184118   Chr4 : 9,633,169
0.001 0.999 0.000
rs191279589 lBF = 0.00005988   Chr4 : 105,605,997
0.001 0.999 0.000
rs74284780 lBF = 0.0288043   Chr4 : 6,937,801
0.001 0.999 0.000
rs13136331 lBF = -0.0709494   Chr4 : 88,707,081
0.001 0.999 0.000
rs76289367 lBF = 3.53377   Chr4 : 155,546,159
0.001 0.999 0.000
rs13143871 lBF = 0.998516   Chr4 : 156,619,204
0.000 0.999 0.001
rs17054392 lBF = 0.0027959   Chr4 : 169,530,258
0.001 0.999 0.000
rs7653911 lBF = 0.049382   Chr4 : 33,655,673
0.001 0.999 0.000
rs75764011 lBF = 0.00206279   Chr4 : 149,574,749
0.000 0.999 0.001
rs17090640 lBF = -0.0311028   Chr4 : 180,667,647
0.001 0.999 0.000
rs7660520 lBF = -0.094001   Chr4 : 183,745,321
0.001 0.999 0.000
rs16845887 lBF = -0.0130996   Chr4 : 72,005,823
0.000 0.999 0.001
rs190972371 lBF = 0.00118746   Chr4 : 57,680,410
0.001 0.999 0.000
rs7656730 lBF = 0.00116967   Chr4 : 40,159,617
0.001 0.999 0.000
rs2518590 lBF = 0.00067505   Chr4 : 17,435,090
0.001 0.999 0.000
rs28498976 lBF = -0.0892675   Chr4 : 31,151,357
0.000 0.999 0.001
rs115426111 lBF = 0.00086143   Chr4 : 38,161,064
0.001 0.999 0.000
rs1443170 lBF = 0.00036453   Chr4 : 128,320,908
0.001 0.999 0.000
rs7669317 lBF = -0.0677321   Chr4 : 106,457,330
0.001 0.999 0.000
rs186873296 lBF = 0.00051343   Chr4 : 144,702,474
0.001 0.999 0.000
rs16996151 lBF = 0.00044095   Chr4 : 89,978,800
0.001 0.999 0.000
rs73838658 lBF = 0.0004191   Chr4 : 105,887,308
0.001 0.999 0.000
rs17031671 lBF = 0.00034476   Chr4 : 155,389,247
0.001 0.999 0.000
rs1044352 lBF = -0.0159602   Chr4 : 31,147,874
0.000 0.999 0.001
rs143750764 lBF = 0.103667   Chr4 : 106,934,057
0.001 0.999 0.000
rs9997524 lBF = 0.00006403   Chr4 : 43,052,186
0.001 0.999 0.000
rs73838655 lBF = 0   Chr4 : 105,874,586
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs142210607 lBF = 0   Chr4 : 55,751,694
0.001 0.999 0.001
rs144063842 lBF = 0   Chr4 : 67,400,255
0.001 0.999 0.001
rs73838632 lBF = 0   Chr4 : 105,783,389
0.001 0.999 0.001
rs61095879 lBF = 0   Chr4 : 105,579,101
0.001 0.999 0.001
rs186699656 lBF = 0   Chr4 : 147,040,943
0.001 0.999 0.001
rs73838652 lBF = 0   Chr4 : 105,871,450
0.001 0.999 0.001
rs73838643 lBF = 0   Chr4 : 105,822,559
0.001 0.999 0.001
rs114681481 lBF = 0   Chr4 : 67,330,261
0.001 0.999 0.001
rs77285130 lBF = 0   Chr4 : 105,729,020
0.001 0.999 0.001
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0.001 0.999 0.001
rs74341662 lBF = 0   Chr4 : 105,879,194
0.001 0.999 0.001
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0.001 0.999 0.001
rs145688504 lBF = 0   Chr4 : 93,704,690
0.001 0.999 0.001
rs73838634 lBF = 0   Chr4 : 105,794,045
0.001 0.999 0.001
rs73838071 lBF = 0   Chr4 : 106,196,977
0.001 0.999 0.001
rs144575900 lBF = 0   Chr4 : 58,872,912
0.001 0.999 0.001
rs181995593 lBF = 0   Chr4 : 21,883,085
0.001 0.999 0.001
rs148386737 lBF = 0   Chr4 : 43,890,440
0.001 0.999 0.001
rs73838653 lBF = 0   Chr4 : 105,871,725
0.001 0.999 0.001
rs73838644 lBF = 0   Chr4 : 105,825,134
0.001 0.999 0.001
rs191540052 lBF = 0   Chr4 : 4,887,114
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs1859156 lBF = 0   Chr4 : 95,834,034
0.001 0.999 0.001
rs78736651 lBF = 0   Chr4 : 105,736,259
0.001 0.999 0.001
rs908084 lBF = 0   Chr4 : 183,543,648
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs140671052 lBF = 0   Chr4 : 93,101,088
0.001 0.999 0.001
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0.001 0.999 0.001
rs114120854 lBF = 0   Chr4 : 67,360,667
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
rs17002342 lBF = -0.00054291   Chr4 : 77,955,205
0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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rs4698036 lBF = 57.8249   Chr4 : 10,331,294
0.000 0.999 0.000
rs7655751 lBF = 23.9932   Chr4 : 149,633,421
0.000 0.999 0.000
rs76966743 lBF = 0.139633   Chr4 : 138,144,790
0.000 0.999 0.000
rs34734558 lBF = 0.10287   Chr4 : 100,530,143
0.000 0.999 0.000
rs713224 lBF = 0.0976616   Chr4 : 187,412,367
0.000 0.999 0.000
rs72673891 lBF = 0.0825667   Chr4 : 106,814,302
0.000 0.999 0.000
rs10033119 lBF = 0.046914   Chr4 : 164,245,854
0.000 0.999 0.000
rs6827815 lBF = 0.0407812   Chr4 : 999,445
0.000 0.999 0.000
rs17641529 lBF = 0.0342786   Chr4 : 44,212,165
0.000 0.999 0.000
rs76930906 lBF = 0.0306957   Chr4 : 175,095,875
0.000 0.999 0.000
rs72686452 lBF = 0.00782207   Chr4 : 98,830,563
0.000 0.999 0.000
rs115641191 lBF = 0.00187345   Chr4 : 103,054,209
0.000 0.999 0.000
rs16872248 lBF = -0.00456178   Chr4 : 22,021,500
0.000 0.999 0.000
rs28534493 lBF = -0.0160908   Chr4 : 61,037,655
0.000 0.999 0.000
rs13132430 lBF = -0.0209346   Chr4 : 100,224,070
0.000 0.999 0.000
rs17017235 lBF = -0.0261655   Chr4 : 91,515,265
0.000 0.999 0.000
rs140913323 lBF = -0.027587   Chr4 : 125,740,709
0.000 0.999 0.000
rs10516526 lBF = -0.0304375   Chr4 : 106,688,904
0.000 0.999 0.000
rs3792615 lBF = -0.0313114   Chr4 : 164,532,801
0.000 0.999 0.000
rs115154496 lBF = -0.032135   Chr4 : 153,661,060
0.000 0.999 0.000
rs71595688 lBF = -0.033041   Chr4 : 53,217,472
0.000 0.999 0.000
rs141990949 lBF = -0.0356617   Chr4 : 81,364,420
0.000 0.999 0.000
rs55645543 lBF = -0.0394778   Chr4 : 122,607,178
0.000 0.999 0.000
rs115136538 lBF = -0.0464542   Chr4 : 73,322,565
0.000 0.999 0.000
rs73250776 lBF = -0.0466142   Chr4 : 23,408,210
0.000 0.999 0.000
rs17580163 lBF = -0.0532701   Chr4 : 58,140,073
0.000 0.999 0.000
rs17039583 lBF = -0.0653683   Chr4 : 109,880,730
0.000 0.999 0.000
rs13105680 lBF = -0.0668766   Chr4 : 108,280,221
0.000 0.999 0.000
rs28668773 lBF = -0.0737298   Chr4 : 99,523,890
0.000 0.999 0.000
rs7698623 lBF = -0.0924458   Chr4 : 88,755,828
0.000 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.