TreeWAS – Mitral valve disease

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs1169288 lBF = `15.7829` Chr`12` : `121,416,650`	0.444	0.556	0.000
rs11057830 lBF = `5.63146` Chr`12` : `125,307,053`	0.435	0.565	0.000
rs1183910 lBF = `13.9986` Chr`12` : `121,420,807`	0.435	0.565	0.000
rs2244608 lBF = `16.1328` Chr`12` : `121,416,988`	0.406	0.593	0.000
rs2244608 lBF = `16.4822` Chr`12` : `121,416,988`	0.379	0.621	0.000
rs11057841 lBF = `4.36815` Chr`12` : `125,316,743`	0.368	0.632	0.000
rs10846744 lBF = `5.73615` Chr`12` : `125,312,425`	0.350	0.650	0.000
rs10774624 lBF = `105.824` Chr`12` : `111,833,788`	0.000	0.664	0.336
rs653178 lBF = `119.357` Chr`12` : `112,007,756`	0.000	0.677	0.323
rs11057830 lBF = `5.90329` Chr`12` : `125,307,053`	0.323	0.677	0.000
rs3184504 lBF = `122.933` Chr`12` : `111,884,608`	0.323	0.677	0.000
rs3184504 lBF = `123.197` Chr`12` : `111,884,608`	0.000	0.679	0.321
rs7310615 lBF = `119.478` Chr`12` : `111,865,049`	0.000	0.684	0.316
rs597808 lBF = `119.587` Chr`12` : `111,973,358`	0.000	0.692	0.308
rs7137828 lBF = `119.978` Chr`12` : `111,932,800`	0.000	0.694	0.306
rs4766578 lBF = `117.059` Chr`12` : `111,904,371`	0.000	0.710	0.290
rs10774625 lBF = `116.314` Chr`12` : `111,910,219`	0.000	0.711	0.289
rs17696736 lBF = `65.495` Chr`12` : `112,486,818`	0.273	0.727	0.000
rs11065987 lBF = `80.7285` Chr`12` : `112,072,424`	0.268	0.732	0.000
rs11066301 lBF = `63.955` Chr`12` : `112,871,372`	0.253	0.747	0.000
rs17630235 lBF = `71.1614` Chr`12` : `112,591,686`	0.247	0.753	0.000
rs116877397 lBF = `1.00264` Chr`12` : `121,162,996`	0.241	0.759	0.000
rs1265564 lBF = `69.221` Chr`12` : `111,708,458`	0.207	0.793	0.000
rs2251468 lBF = `10.8012` Chr`12` : `121,405,126`	0.000	0.793	0.207
rs11065979 lBF = `86.6197` Chr`12` : `112,059,557`	0.205	0.795	0.000
rs11045000 lBF = `0.457194` Chr`12` : `20,184,146`	0.000	0.888	0.111
rs11057864 lBF = `0.577325` Chr`12` : `125,335,950`	0.097	0.903	0.000
rs2650000 lBF = `10.2762` Chr`12` : `121,388,962`	0.000	0.912	0.088
rs79476482 lBF = `0.185768` Chr`12` : `76,084,550`	0.040	0.959	0.000
rs7135659 lBF = `2.45758` Chr`12` : `114,801,772`	0.027	0.973	0.000
rs1895585 lBF = `2.57` Chr`12` : `114,802,138`	0.025	0.975	0.000
rs7979473 lBF = `7.9078` Chr`12` : `121,420,260`	0.000	0.976	0.024
rs7968682 lBF = `2.65218` Chr`12` : `66,371,880`	0.018	0.982	0.000
rs883079 lBF = `2.94216` Chr`12` : `114,793,240`	0.017	0.983	0.000
rs4149639 lBF = `0.0707031` Chr`12` : `6,442,001`	0.014	0.986	0.000
rs8756 lBF = `2.39619` Chr`12` : `66,359,752`	0.012	0.988	0.000
rs117559199 lBF = `0.0444141` Chr`12` : `75,424,551`	0.010	0.990	0.000
rs7312625 lBF = `2.7813` Chr`12` : `114,799,974`	0.008	0.992	0.000
rs1351394 lBF = `2.2176` Chr`12` : `66,351,826`	0.008	0.992	0.000
rs77821460 lBF = `0.0333624` Chr`12` : `20,274,936`	0.000	0.993	0.007
rs7310409 lBF = `7.3854` Chr`12` : `121,424,861`	0.000	0.993	0.007
rs2393791 lBF = `7.53249` Chr`12` : `121,423,956`	0.000	0.993	0.006
rs117636037 lBF = `-0.0230629` Chr`12` : `38,519,375`	0.006	0.994	0.000
rs1971762 lBF = `-0.171332` Chr`12` : `54,058,238`	0.000	0.995	0.005
rs7970350 lBF = `2.85283` Chr`12` : `66,360,164`	0.005	0.995	0.000
rs12579720 lBF = `-0.0473502` Chr`12` : `20,173,764`	0.005	0.995	0.000
rs181609621 lBF = `0.0305731` Chr`12` : `32,810,759`	0.004	0.995	0.000
rs1042725 lBF = `2.99712` Chr`12` : `66,358,347`	0.004	0.996	0.000
rs79235855 lBF = `0.0255225` Chr`12` : `1,537,749`	0.003	0.996	0.000
rs10784502 lBF = `2.14075` Chr`12` : `66,343,810`	0.003	0.997	0.000
rs10431397 lBF = `0.0312462` Chr`12` : `118,106,194`	0.000	0.997	0.003
rs11170631 lBF = `-0.167789` Chr`12` : `54,041,192`	0.000	0.997	0.003
rs1169314 lBF = `9.62668` Chr`12` : `121,443,116`	0.003	0.997	0.000
rs1151008 lBF = `-0.185989` Chr`12` : `32,097,360`	0.000	0.997	0.003
rs2965667 lBF = `-0.0038135` Chr`12` : `17,444,733`	0.003	0.997	0.000
rs2217235 lBF = `-0.152052` Chr`12` : `87,145,223`	0.000	0.997	0.003
rs4304868 lBF = `-0.172341` Chr`12` : `118,169,909`	0.000	0.997	0.003
rs2264750 lBF = `9.96752` Chr`12` : `121,450,165`	0.003	0.997	0.000
rs739496 lBF = `15.7606` Chr`12` : `111,887,659`	0.000	0.997	0.003
rs76595471 lBF = `0.281433` Chr`12` : `80,228,443`	0.002	0.997	0.000
rs4763879 lBF = `16.4993` Chr`12` : `9,910,164`	0.000	0.997	0.003
rs7970953 lBF = `-0.117578` Chr`12` : `24,075,508`	0.000	0.997	0.003
rs741627 lBF = `-0.116847` Chr`12` : `114,206,076`	0.000	0.997	0.002
rs1502337 lBF = `0.0734824` Chr`12` : `111,062,852`	0.000	0.997	0.002
rs118009632 lBF = `-0.00778441` Chr`12` : `54,959,672`	0.000	0.998	0.002
rs11612228 lBF = `-0.0707396` Chr`12` : `576,984`	0.002	0.998	0.000
rs9943753 lBF = `-0.0603396` Chr`12` : `109,840,940`	0.002	0.998	0.000
rs74377925 lBF = `-0.00355927` Chr`12` : `16,699,250`	0.000	0.998	0.002
rs10492002 lBF = `-0.180145` Chr`12` : `81,544,536`	0.000	0.998	0.002
rs2338104 lBF = `-0.156996` Chr`12` : `109,895,168`	0.002	0.998	0.000
rs3764021 lBF = `14.5791` Chr`12` : `9,833,628`	0.002	0.998	0.000
rs7296313 lBF = `15.6606` Chr`12` : `111,878,526`	0.000	0.998	0.002
rs181947843 lBF = `0.0630024` Chr`12` : `108,547,387`	0.000	0.998	0.002
rs141480969 lBF = `-0.00812947` Chr`12` : `62,496,278`	0.002	0.998	0.000
rs7134594 lBF = `-0.156638` Chr`12` : `110,000,193`	0.002	0.998	0.000
rs1043607 lBF = `-0.162824` Chr`12` : `126,143,346`	0.002	0.998	0.000
rs10770612 lBF = `0.234735` Chr`12` : `20,230,639`	0.002	0.998	0.000
rs182057829 lBF = `0.0178491` Chr`12` : `97,412,327`	0.002	0.998	0.000
rs1979679 lBF = `-0.041503` Chr`12` : `28,406,515`	0.000	0.998	0.002
rs7316650 lBF = `1.55515` Chr`12` : `112,439,664`	0.000	0.998	0.002
rs2417820 lBF = `-0.0710614` Chr`12` : `20,190,474`	0.000	0.998	0.002
rs7954638 lBF = `0.873881` Chr`12` : `96,314,795`	0.002	0.998	0.000
rs11053548 lBF = `-0.146368` Chr`12` : `10,170,727`	0.000	0.998	0.002
rs1520223 lBF = `0.00922955` Chr`12` : `102,726,338`	0.002	0.998	0.000
rs2241208 lBF = `-0.173332` Chr`12` : `109,962,795`	0.002	0.998	0.000
rs10841287 lBF = `-0.0545352` Chr`12` : `19,779,793`	0.002	0.998	0.000
rs11174812 lBF = `-0.17877` Chr`12` : `40,425,087`	0.002	0.998	0.000
rs1795851 lBF = `-0.182218` Chr`12` : `104,925,884`	0.000	0.998	0.002
rs12310399 lBF = `-0.238336` Chr`12` : `95,490,248`	0.002	0.998	0.000
rs16906714 lBF = `0.00916885` Chr`12` : `30,860,557`	0.002	0.998	0.000
rs2669010 lBF = `-0.0796214` Chr`12` : `77,009,060`	0.000	0.998	0.002
rs11048674 lBF = `0.027584` Chr`12` : `26,912,719`	0.001	0.998	0.000
rs6486986 lBF = `0.288504` Chr`12` : `19,801,595`	0.000	0.998	0.001
rs4251424 lBF = `0.011513` Chr`12` : `44,153,826`	0.001	0.998	0.000
rs2722223 lBF = `0.573838` Chr`12` : `90,233,876`	0.001	0.998	0.000
rs4761097 lBF = `-0.120652` Chr`12` : `85,187,511`	0.002	0.998	0.000
rs10745527 lBF = `-0.16607` Chr`12` : `90,609,017`	0.002	0.998	0.000
rs2887571 lBF = `0.413003` Chr`12` : `1,638,171`	0.002	0.998	0.000
rs10783779 lBF = `8.28338` Chr`12` : `56,491,880`	0.002	0.998	0.000
rs3825214 lBF = `0.457593` Chr`12` : `114,795,443`	0.002	0.998	0.000
rs4767631 lBF = `-0.116118` Chr`12` : `118,311,743`	0.002	0.998	0.000
rs3213545 lBF = `8.51031` Chr`12` : `121,471,337`	0.001	0.998	0.000
rs10774740 lBF = `-0.0110487` Chr`12` : `114,666,202`	0.001	0.998	0.000
rs2887631 lBF = `-0.0884013` Chr`12` : `1,934,581`	0.002	0.998	0.000
rs2072510 lBF = `-0.104676` Chr`12` : `96,403,199`	0.000	0.998	0.001
rs144288546 lBF = `0.00756471` Chr`12` : `129,069,682`	0.001	0.999	0.000
rs2579103 lBF = `-0.175853` Chr`12` : `90,633,507`	0.001	0.999	0.000
rs10850408 lBF = `-0.053905` Chr`12` : `115,380,393`	0.000	0.999	0.001
rs12815303 lBF = `-0.0721583` Chr`12` : `62,387,183`	0.000	0.999	0.001
rs12817007 lBF = `-0.0725341` Chr`12` : `62,387,282`	0.000	0.999	0.001
rs2216228 lBF = `-0.111883` Chr`12` : `22,365,835`	0.001	0.999	0.000
rs12817011 lBF = `-0.0680504` Chr`12` : `62,387,287`	0.000	0.999	0.001
rs11174267 lBF = `-0.0792009` Chr`12` : `62,386,600`	0.000	0.999	0.001
rs10843013 lBF = `-0.0938979` Chr`12` : `28,025,196`	0.000	0.999	0.001
rs11052552 lBF = `16.2756` Chr`12` : `9,855,958`	0.000	0.999	0.001
rs7312770 lBF = `12.0494` Chr`12` : `56,467,587`	0.000	0.999	0.001
rs7138803 lBF = `-0.0244725` Chr`12` : `50,247,468`	0.000	0.999	0.001
rs704178 lBF = `-0.118484` Chr`12` : `21,993,478`	0.000	0.999	0.001
rs4149018 lBF = `0.00225297` Chr`12` : `21,291,561`	0.001	0.999	0.000
rs941184 lBF = `0.00819985` Chr`12` : `54,114,158`	0.001	0.999	0.000
rs187607716 lBF = `0.0054758` Chr`12` : `91,487,517`	0.000	0.999	0.001
rs7953249 lBF = `6.30433` Chr`12` : `121,403,724`	0.000	0.999	0.001
rs17012589 lBF = `0.118446` Chr`12` : `85,516,904`	0.000	0.999	0.001
rs187293782 lBF = `0.00420279` Chr`12` : `76,157,356`	0.001	0.999	0.000
rs216303 lBF = `3.73293` Chr`12` : `6,159,045`	0.001	0.999	0.000
rs186586221 lBF = `0.0366186` Chr`12` : `75,574,323`	0.000	0.999	0.001
rs4767364 lBF = `16.7662` Chr`12` : `112,521,448`	0.001	0.999	0.000
rs1082714 lBF = `-0.164922` Chr`12` : `67,628,831`	0.000	0.999	0.001
rs183032784 lBF = `0.00122659` Chr`12` : `118,257,214`	0.001	0.999	0.000
rs11175944 lBF = `-0.0286832` Chr`12` : `66,256,395`	0.001	0.999	0.000
rs10772939 lBF = `-0.107567` Chr`12` : `16,609,038`	0.000	0.999	0.001
rs61935443 lBF = `-0.201687` Chr`12` : `95,249,764`	0.000	0.999	0.001
rs4468442 lBF = `-0.226466` Chr`12` : `59,651,225`	0.001	0.999	0.000
rs11066313 lBF = `2.50599` Chr`12` : `112,893,414`	0.001	0.999	0.000
rs147616082 lBF = `0.00586878` Chr`12` : `67,181,789`	0.001	0.999	0.000
rs7307780 lBF = `-0.069015` Chr`12` : `76,220,618`	0.001	0.999	0.000
rs10773049 lBF = `-0.0963188` Chr`12` : `124,506,631`	0.000	0.999	0.001
rs863750 lBF = `-0.0990942` Chr`12` : `124,505,444`	0.001	0.999	0.000
rs2066955 lBF = `-0.110827` Chr`12` : `82,090,616`	0.001	0.999	0.000
rs12146838 lBF = `-0.120618` Chr`12` : `92,375,595`	0.000	0.999	0.001
rs4554975 lBF = `-0.152736` Chr`12` : `47,201,814`	0.001	0.999	0.000
rs80130819 lBF = `-0.00272101` Chr`12` : `48,419,618`	0.001	0.999	0.000
rs3803064 lBF = `4.52925` Chr`12` : `113,173,494`	0.000	0.999	0.001
rs181697701 lBF = `-0.00452138` Chr`12` : `107,611,050`	0.001	0.999	0.000
rs147510300 lBF = `0.00135014` Chr`12` : `86,318,548`	0.001	0.999	0.000
rs150696478 lBF = `0.00135014` Chr`12` : `86,321,388`	0.001	0.999	0.000
rs117626015 lBF = `0.00041926` Chr`12` : `41,624,795`	0.001	0.999	0.000
rs187039407 lBF = `-0.0136559` Chr`12` : `87,341,774`	0.000	0.999	0.001
rs1011728 lBF = `-0.0391698` Chr`12` : `85,695,613`	0.000	0.999	0.001
rs10859525 lBF = `-0.101938` Chr`12` : `93,948,457`	0.001	0.999	0.000
rs7136259 lBF = `-0.171653` Chr`12` : `90,081,188`	0.001	0.999	0.000
rs2292354 lBF = `0.132168` Chr`12` : `110,368,201`	0.001	0.999	0.000
rs1040026 lBF = `-0.00021934` Chr`12` : `71,210,678`	0.001	0.999	0.000
rs10492336 lBF = `-0.150721` Chr`12` : `114,585,580`	0.001	0.999	0.000
rs4326884 lBF = `-0.107768` Chr`12` : `20,536,371`	0.000	0.999	0.001
rs35444 lBF = `-0.132511` Chr`12` : `115,552,437`	0.000	0.999	0.001
rs2268146 lBF = `15.3822` Chr`12` : `9,869,271`	0.001	0.999	0.000
rs10875976 lBF = `0.289041` Chr`12` : `50,226,467`	0.000	0.999	0.001
rs1718309 lBF = `-0.162354` Chr`12` : `103,242,396`	0.000	0.999	0.001
rs147538848 lBF = `0.00200609` Chr`12` : `31,466,613`	0.001	0.999	0.000
rs116938548 lBF = `0.00088785` Chr`12` : `4,808,251`	0.000	0.999	0.001
rs10400419 lBF = `-0.0216977` Chr`12` : `66,389,968`	0.001	0.999	0.000
rs78574971 lBF = `-0.0543084` Chr`12` : `52,023,925`	0.001	0.999	0.000
rs11168351 lBF = `-0.0616752` Chr`12` : `48,403,765`	0.000	0.999	0.001
rs11065706 lBF = `-0.0698098` Chr`12` : `111,155,531`	0.000	0.999	0.001
rs35444 lBF = `-0.0933489` Chr`12` : `115,552,437`	0.000	0.999	0.001
rs182328274 lBF = `0.00022951` Chr`12` : `107,667,802`	0.001	0.999	0.000
rs116962450 lBF = `-0.0188444` Chr`12` : `90,500,741`	0.001	0.999	0.000
rs2270788 lBF = `-0.0573463` Chr`12` : `123,414,349`	0.001	0.999	0.000
rs1457614 lBF = `-0.138723` Chr`12` : `13,641,706`	0.001	0.999	0.000
rs2285810 lBF = `15.0111` Chr`12` : `112,699,540`	0.001	0.999	0.000
rs189340018 lBF = `0.00021348` Chr`12` : `107,628,680`	0.001	0.999	0.000
rs10467147 lBF = `0.3842` Chr`12` : `40,767,362`	0.001	0.999	0.000
rs4594074 lBF = `0.00070944` Chr`12` : `41,032,092`	0.001	0.999	0.000
rs190262953 lBF = `0.00002888` Chr`12` : `91,825,974`	0.001	0.999	0.000
rs192256367 lBF = `0` Chr`12` : `107,648,405`	0.001	0.999	0.001
rs3782886 lBF = `0` Chr`12` : `112,110,489`	0.001	0.999	0.001
rs918304 lBF = `0` Chr`12` : `108,877,541`	0.001	0.999	0.001
rs12582168 lBF = `0` Chr`12` : `124,894,184`	0.001	0.999	0.001
rs11174436 lBF = `0` Chr`12` : `62,743,348`	0.001	0.999	0.001
rs111696067 lBF = `0` Chr`12` : `133,376,540`	0.001	0.999	0.001
rs2072134 lBF = `0` Chr`12` : `113,409,176`	0.001	0.999	0.001
rs12300553 lBF = `0` Chr`12` : `15,381,210`	0.001	0.999	0.001
rs2074356 lBF = `0` Chr`12` : `112,645,401`	0.001	0.999	0.001
rs78852656 lBF = `0` Chr`12` : `119,619,997`	0.001	0.999	0.001
rs191413231 lBF = `0` Chr`12` : `13,630,602`	0.001	0.999	0.001
rs191000678 lBF = `0` Chr`12` : `28,286,990`	0.001	0.999	0.001
rs8179116 lBF = `0` Chr`12` : `109,025,427`	0.001	0.999	0.001
rs12423382 lBF = `0` Chr`12` : `16,179,371`	0.001	0.999	0.001
rs2188380 lBF = `0` Chr`12` : `111,386,127`	0.001	0.999	0.001
rs139337462 lBF = `0` Chr`12` : `29,984,300`	0.001	0.999	0.001
rs192568883 lBF = `0` Chr`12` : `107,606,126`	0.001	0.999	0.001
rs671 lBF = `0` Chr`12` : `112,241,766`	0.001	0.999	0.001
rs117876032 lBF = `0` Chr`12` : `125,736,003`	0.001	0.999	0.001
rs4542491 lBF = `0` Chr`12` : `82,536,844`	0.001	0.999	0.001
rs12311304 lBF = `0` Chr`12` : `15,389,637`	0.001	0.999	0.001
rs11066015 lBF = `0` Chr`12` : `112,168,009`	0.001	0.999	0.001
rs139427007 lBF = `0` Chr`12` : `97,596,103`	0.001	0.999	0.001
rs151326733 lBF = `0` Chr`12` : `16,189,478`	0.001	0.999	0.001
rs138037897 lBF = `0` Chr`12` : `29,985,498`	0.001	0.999	0.001
rs193047854 lBF = `0` Chr`12` : `56,274,155`	0.001	0.999	0.001
rs183884080 lBF = `0` Chr`12` : `68,621,977`	0.001	0.999	0.001
rs146978549 lBF = `0` Chr`12` : `17,049,912`	0.001	0.999	0.001
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rs11116045 lBF = `-0.182859` Chr`12` : `84,196,529`	0.001	0.999	0.000
rs1727313 lBF = `1.14495` Chr`12` : `123,640,853`	0.000	0.999	0.000
rs73313995 lBF = `0.0908007` Chr`12` : `33,622,807`	0.000	0.999	0.000
rs1513049 lBF = `0.0677764` Chr`12` : `17,362,816`	0.000	0.999	0.000
rs59753639 lBF = `-0.0242957` Chr`12` : `25,140,690`	0.000	0.999	0.000
rs11064768 lBF = `-0.0653584` Chr`12` : `119,818,509`	0.000	0.999	0.000
rs11104268 lBF = `-0.0867955` Chr`12` : `76,627,445`	0.000	0.999	0.000
rs763564 lBF = `-0.0936393` Chr`12` : `91,024,916`	0.001	0.999	0.000
rs6488099 lBF = `-0.112351` Chr`12` : `33,035,483`	0.001	0.999	0.000
rs483610 lBF = `-0.146446` Chr`12` : `99,334,529`	0.001	0.999	0.000
rs7313402 lBF = `-0.240787` Chr`12` : `108,602,970`	0.001	0.999	0.000
rs10744777 lBF = `24.7136` Chr`12` : `112,233,018`	0.000	0.999	0.000
rs11612508 lBF = `0.111622` Chr`12` : `12,657,513`	0.000	0.999	0.001
rs2292303 lBF = `0.0517287` Chr`12` : `102,513,531`	0.000	0.999	0.000
rs12582659 lBF = `0.0164759` Chr`12` : `76,064,528`	0.000	0.999	0.000
rs11115322 lBF = `-0.00566265` Chr`12` : `83,019,188`	0.000	0.999	0.000
rs139680557 lBF = `-0.0117415` Chr`12` : `108,061,589`	0.000	0.999	0.000
rs10506821 lBF = `-0.0178868` Chr`12` : `80,496,923`	0.000	0.999	0.000
rs12582852 lBF = `-0.0201787` Chr`12` : `3,315,933`	0.000	0.999	0.000
rs61941274 lBF = `-0.0212991` Chr`12` : `112,132,610`	0.000	0.999	0.000
rs78294386 lBF = `-0.025636` Chr`12` : `107,963,652`	0.000	0.999	0.000
rs4930776 lBF = `-0.0292519` Chr`12` : `5,767,385`	0.000	0.999	0.001
rs2660869 lBF = `-0.0293874` Chr`12` : `96,479,267`	0.000	0.999	0.000
rs76242156 lBF = `-0.0426901` Chr`12` : `65,043,774`	0.000	0.999	0.000
rs17719439 lBF = `-0.0495698` Chr`12` : `116,211,863`	0.000	0.999	0.000
rs1961649 lBF = `-0.0540866` Chr`12` : `99,904,540`	0.000	0.999	0.000
rs2638315 lBF = `-0.0551175` Chr`12` : `56,865,056`	0.000	0.999	0.000
rs17126180 lBF = `-0.0871769` Chr`12` : `52,263,956`	0.000	0.999	0.000
rs66861122 lBF = `-0.0991321` Chr`12` : `101,383,958`	0.000	0.999	0.000
rs7961894 lBF = `-0.102445` Chr`12` : `122,365,583`	0.000	0.999	0.000
rs12230440 lBF = `-0.103819` Chr`12` : `1,856,953`	0.001	0.999	0.000
rs11054786 lBF = `-0.120315` Chr`12` : `12,458,665`	0.000	0.999	0.000
rs1531228 lBF = `-0.132537` Chr`12` : `13,629,381`	0.001	0.999	0.000
rs10841530 lBF = `-0.141551` Chr`12` : `20,599,112`	0.000	0.999	0.001
rs718314 lBF = `-0.156409` Chr`12` : `26,453,283`	0.000	0.999	0.001
rs10842750 lBF = `-0.217443` Chr`12` : `26,690,565`	0.001	0.999	0.000
rs11171739 lBF = `17.4895` Chr`12` : `56,470,625`	0.000	0.999	0.000
rs12370275 lBF = `0.460946` Chr`12` : `61,907,022`	0.000	0.999	0.000
rs12422544 lBF = `0.417415` Chr`12` : `40,528,432`	0.000	0.999	0.000
rs12810016 lBF = `0.34114` Chr`12` : `83,308,363`	0.000	0.999	0.000
rs79946301 lBF = `-0.0107273` Chr`12` : `130,117,149`	0.000	0.999	0.000
rs12425131 lBF = `-0.0263199` Chr`12` : `82,984,879`	0.000	0.999	0.000
rs35729753 lBF = `-0.0330626` Chr`12` : `66,672,379`	0.000	0.999	0.000
rs79918060 lBF = `-0.0463353` Chr`12` : `58,407,669`	0.000	0.999	0.000
rs10848911 lBF = `-0.046803` Chr`12` : `3,814,238`	0.000	0.999	0.000
rs11066587 lBF = `-0.0635284` Chr`12` : `113,979,656`	0.000	0.999	0.000
rs4965006 lBF = `-0.0715269` Chr`12` : `132,419,533`	0.000	0.999	0.000
rs10771515 lBF = `-0.0722869` Chr`12` : `9,463,806`	0.000	0.999	0.000
rs11047543 lBF = `-0.0846995` Chr`12` : `24,788,339`	0.000	0.999	0.000
rs17101923 lBF = `-0.0960443` Chr`12` : `66,338,202`	0.001	0.999	0.000
rs7953528 lBF = `-0.106363` Chr`12` : `28,017,159`	0.000	0.999	0.000
rs2277339 lBF = `-0.115392` Chr`12` : `57,146,069`	0.000	0.999	0.000
rs34934130 lBF = `-0.118036` Chr`12` : `121,502,913`	0.000	0.999	0.000
rs11106179 lBF = `-0.131957` Chr`12` : `91,896,412`	0.000	0.999	0.000
rs4760099 lBF = `-0.142319` Chr`12` : `122,318,723`	0.000	0.999	0.000
rs11168249 lBF = `-0.158937` Chr`12` : `48,208,368`	0.001	0.999	0.000
rs522958 lBF = `-0.166804` Chr`12` : `28,228,567`	0.001	0.999	0.000
rs7953929 lBF = `0.644754` Chr`12` : `123,758,235`	0.000	0.999	0.000
rs118079879 lBF = `0.322351` Chr`12` : `41,713,306`	0.000	0.999	0.000
rs1442190 lBF = `0.0617111` Chr`12` : `41,365,640`	0.000	0.999	0.000
rs4759375 lBF = `0.0210862` Chr`12` : `123,796,238`	0.000	0.999	0.000
rs74910874 lBF = `0.00657792` Chr`12` : `67,086,810`	0.000	0.999	0.000
rs139660738 lBF = `-0.0113457` Chr`12` : `95,185,188`	0.000	0.999	0.000
rs10848820 lBF = `-0.0190427` Chr`12` : `3,296,948`	0.000	0.999	0.000
rs17124610 lBF = `-0.0265624` Chr`12` : `61,549,081`	0.000	0.999	0.000
rs17184007 lBF = `-0.027907` Chr`12` : `67,594,578`	0.000	0.999	0.000
rs116075389 lBF = `-0.0332697` Chr`12` : `68,957,164`	0.000	0.999	0.000
rs114588203 lBF = `-0.0337929` Chr`12` : `68,956,185`	0.000	0.999	0.000
rs150516896 lBF = `-0.0338119` Chr`12` : `68,955,572`	0.000	0.999	0.000
rs7968324 lBF = `-0.07431` Chr`12` : `59,066,580`	0.000	0.999	0.000
rs12423712 lBF = `-0.0975809` Chr`12` : `125,033,933`	0.000	0.999	0.000
rs11069062 lBF = `-0.108402` Chr`12` : `119,163,079`	0.001	0.999	0.000
rs258415 lBF = `-0.110593` Chr`12` : `28,017,522`	0.000	0.999	0.000
rs34102591 lBF = `-0.116043` Chr`12` : `124,480,801`	0.000	0.999	0.000
rs10878340 lBF = `-0.119624` Chr`12` : `40,695,095`	0.001	0.999	0.000
rs11062578 lBF = `-0.135568` Chr`12` : `3,327,167`	0.000	0.999	0.000
rs3816804 lBF = `-0.142155` Chr`12` : `56,680,745`	0.000	0.999	0.000
rs7314056 lBF = `-0.143734` Chr`12` : `122,342,964`	0.000	0.999	0.000
rs12829704 lBF = `-0.199875` Chr`12` : `21,388,621`	0.000	0.999	0.000
rs6489785 lBF = `0.70492` Chr`12` : `121,363,724`	0.000	0.999	0.001
rs7309269 lBF = `0.540911` Chr`12` : `7,757,834`	0.000	0.999	0.000
rs10845606 lBF = `0.187771` Chr`12` : `12,834,894`	0.000	0.999	0.000
rs10861905 lBF = `0.171661` Chr`12` : `108,767,333`	0.000	0.999	0.000
rs2403106 lBF = `0.0259431` Chr`12` : `84,008,275`	0.000	0.999	0.000
rs11109142 lBF = `0.0219525` Chr`12` : `98,027,691`	0.000	0.999	0.000
rs117624816 lBF = `0.018519` Chr`12` : `18,210,143`	0.000	0.999	0.000
rs17040357 lBF = `0.00427502` Chr`12` : `108,665,316`	0.000	0.999	0.000
rs7307889 lBF = `0.00032551` Chr`12` : `5,981,353`	0.000	0.999	0.000
rs7308134 lBF = `-0.0016619` Chr`12` : `1,987,245`	0.000	0.999	0.000
rs2417957 lBF = `-0.00443214` Chr`12` : `21,323,611`	0.000	0.999	0.000
rs61756485 lBF = `-0.00594164` Chr`12` : `99,020,125`	0.000	0.999	0.000
rs117825839 lBF = `-0.0131986` Chr`12` : `28,978,196`	0.000	0.999	0.000
rs117458579 lBF = `-0.0146201` Chr`12` : `15,351,989`	0.000	0.999	0.000
rs7307123 lBF = `-0.0160241` Chr`12` : `54,524,397`	0.000	0.999	0.000
rs12425131 lBF = `-0.0265939` Chr`12` : `82,984,879`	0.000	0.999	0.000
rs11108227 lBF = `-0.0269599` Chr`12` : `96,134,001`	0.000	0.999	0.000
rs79015790 lBF = `-0.0284797` Chr`12` : `128,700,249`	0.000	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Heart valve problem/heart murmur
Nested terms	Mitral valve prolapse Mitral stenosis Mitral regurgitation / incompetence

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)