TreeWAS – Substance abuse/dependency

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs7829759 lBF = `0.610381` Chr`8` : `3,147,359`	0.000	0.832	0.167
rs17829719 lBF = `0.142146` Chr`8` : `1,824,454`	0.035	0.965	0.000
rs4342585 lBF = `0.520569` Chr`8` : `74,467,504`	0.013	0.986	0.000
rs9314308 lBF = `0.571474` Chr`8` : `25,544,679`	0.000	0.991	0.009
rs6468049 lBF = `0.345636` Chr`8` : `31,342,467`	0.000	0.991	0.009
rs6995588 lBF = `0.0901814` Chr`8` : `61,003,897`	0.008	0.991	0.000
rs2738113 lBF = `0.337538` Chr`8` : `6,829,085`	0.008	0.991	0.000
rs1983474 lBF = `0.0178553` Chr`8` : `4,403,586`	0.008	0.992	0.000
rs72659626 lBF = `0.238942` Chr`8` : `72,920,433`	0.008	0.992	0.000
rs13273088 lBF = `-0.0841819` Chr`8` : `70,493,974`	0.007	0.993	0.000
rs191939331 lBF = `0.182487` Chr`8` : `84,717,650`	0.006	0.994	0.000
rs117500008 lBF = `0.0645869` Chr`8` : `101,671,045`	0.005	0.995	0.000
rs11787111 lBF = `0.0239897` Chr`8` : `65,192,451`	0.004	0.996	0.000
rs72630661 lBF = `0.114487` Chr`8` : `38,329,982`	0.004	0.996	0.000
rs526533 lBF = `-0.0840292` Chr`8` : `102,891,233`	0.004	0.996	0.000
rs1587409 lBF = `-0.0425464` Chr`8` : `118,263,732`	0.004	0.996	0.000
rs1870805 lBF = `-0.0885268` Chr`8` : `140,995,243`	0.004	0.996	0.000
rs187162159 lBF = `0.0140538` Chr`8` : `25,111,606`	0.003	0.997	0.000
rs10086568 lBF = `-0.105335` Chr`8` : `6,900,336`	0.000	0.997	0.003
rs800586 lBF = `1.87083` Chr`8` : `116,813,905`	0.000	0.997	0.003
rs56010636 lBF = `-0.0163429` Chr`8` : `96,866,349`	0.003	0.997	0.000
rs11988906 lBF = `-0.150872` Chr`8` : `4,251,284`	0.000	0.998	0.002
rs74342708 lBF = `0.00465501` Chr`8` : `22,572,749`	0.002	0.998	0.000
rs17669535 lBF = `-0.0314334` Chr`8` : `1,244,224`	0.000	0.998	0.002
rs3019286 lBF = `-0.0265394` Chr`8` : `99,895,405`	0.000	0.998	0.002
rs6601327 lBF = `3.73287` Chr`8` : `9,395,532`	0.000	0.998	0.002
rs17128007 lBF = `0.0147493` Chr`8` : `19,083,152`	0.000	0.998	0.002
rs62532816 lBF = `-0.00261166` Chr`8` : `132,554,452`	0.002	0.998	0.000
rs11779594 lBF = `-0.0941001` Chr`8` : `28,181,755`	0.002	0.998	0.000
rs2720508 lBF = `0.0236256` Chr`8` : `17,329,827`	0.002	0.998	0.000
rs140273521 lBF = `0.0959506` Chr`8` : `136,277,752`	0.002	0.998	0.000
rs77541621 lBF = `-0.0229716` Chr`8` : `128,077,146`	0.002	0.998	0.000
rs16924527 lBF = `0.0920009` Chr`8` : `59,974,175`	0.001	0.998	0.000
rs7845056 lBF = `-0.145449` Chr`8` : `143,020,731`	0.000	0.998	0.002
rs6468852 lBF = `-0.0868919` Chr`8` : `103,975,989`	0.000	0.998	0.001
rs2003880 lBF = `0.910374` Chr`8` : `6,788,102`	0.000	0.998	0.001
rs72657954 lBF = `-0.00355337` Chr`8` : `72,770,306`	0.001	0.998	0.000
rs2705293 lBF = `0.0819572` Chr`8` : `138,918,945`	0.000	0.999	0.001
rs35925379 lBF = `0.00697383` Chr`8` : `144,802,456`	0.001	0.999	0.000
rs7459527 lBF = `0.0042781` Chr`8` : `118,909,260`	0.000	0.999	0.001
rs150281976 lBF = `0.00568202` Chr`8` : `25,131,459`	0.001	0.999	0.000
rs62480124 lBF = `-0.0555511` Chr`8` : `3,778,636`	0.000	0.999	0.001
rs2722425 lBF = `-0.0850965` Chr`8` : `40,484,239`	0.001	0.999	0.000
rs72657970 lBF = `0.00732974` Chr`8` : `72,808,087`	0.001	0.999	0.000
rs149232124 lBF = `0.00353466` Chr`8` : `107,335,395`	0.001	0.999	0.000
rs2129782 lBF = `0.0657365` Chr`8` : `89,459,234`	0.001	0.999	0.000
rs6557600 lBF = `-0.0184023` Chr`8` : `22,763,248`	0.000	0.999	0.001
rs28680850 lBF = `-0.0461782` Chr`8` : `1,373,720`	0.000	0.999	0.001
rs117366179 lBF = `-0.0167841` Chr`8` : `14,733,658`	0.001	0.999	0.000
rs117531883 lBF = `0.0315426` Chr`8` : `8,309,054`	0.000	0.999	0.001
rs10503672 lBF = `-0.0520588` Chr`8` : `19,987,703`	0.000	0.999	0.001
rs7846385 lBF = `-0.0942479` Chr`8` : `78,160,179`	0.001	0.999	0.000
rs4735677 lBF = `-0.108248` Chr`8` : `78,148,191`	0.001	0.999	0.000
rs16906293 lBF = `0.00227664` Chr`8` : `137,768,892`	0.001	0.999	0.000
rs17412740 lBF = `-0.112066` Chr`8` : `20,246,758`	0.000	0.999	0.001
rs2280890 lBF = `-0.00087592` Chr`8` : `22,404,840`	0.001	0.999	0.000
rs150335055 lBF = `0.00366638` Chr`8` : `9,244,264`	0.001	0.999	0.000
rs4545046 lBF = `-0.0242389` Chr`8` : `27,556,526`	0.000	0.999	0.001
rs4736655 lBF = `0.00621516` Chr`8` : `134,350,106`	0.001	0.999	0.001
rs2898261 lBF = `0.00118597` Chr`8` : `10,958,539`	0.001	0.999	0.000
rs7004520 lBF = `-0.05746` Chr`8` : `31,327,049`	0.000	0.999	0.001
rs896854 lBF = `0.469776` Chr`8` : `95,960,511`	0.000	0.999	0.001
rs75631105 lBF = `-0.00828182` Chr`8` : `141,449,601`	0.001	0.999	0.000
rs6990917 lBF = `0.00141955` Chr`8` : `68,799,377`	0.001	0.999	0.000
rs147913210 lBF = `0.00128782` Chr`8` : `25,130,233`	0.001	0.999	0.000
rs2055729 lBF = `0.430859` Chr`8` : `9,792,662`	0.000	0.999	0.001
rs190951784 lBF = `0.00112187` Chr`8` : `25,131,523`	0.001	0.999	0.000
rs4872511 lBF = `-0.0015083` Chr`8` : `22,400,989`	0.001	0.999	0.000
rs284491 lBF = `-0.184846` Chr`8` : `105,958,633`	0.000	0.999	0.001
rs7822058 lBF = `-0.0691822` Chr`8` : `53,684,861`	0.000	0.999	0.001
rs2255327 lBF = `0.00125341` Chr`8` : `11,409,992`	0.001	0.999	0.000
rs182115318 lBF = `0.00072777` Chr`8` : `25,128,723`	0.001	0.999	0.000
rs142487520 lBF = `-0.0210214` Chr`8` : `9,274,376`	0.000	0.999	0.001
rs12549576 lBF = `-0.025567` Chr`8` : `112,976,141`	0.001	0.999	0.000
rs7386474 lBF = `-0.107319` Chr`8` : `142,359,550`	0.001	0.999	0.000
rs73318770 lBF = `0.0005157` Chr`8` : `74,362,915`	0.001	0.999	0.000
rs4484658 lBF = `-0.139652` Chr`8` : `96,208,726`	0.001	0.999	0.000
rs28493987 lBF = `0.00011` Chr`8` : `75,341,097`	0.000	0.999	0.001
rs7004587 lBF = `0.00009449` Chr`8` : `108,040,352`	0.001	0.999	0.000
rs10107366 lBF = `0.00004624` Chr`8` : `99,113,687`	0.001	0.999	0.000
rs141721054 lBF = `0` Chr`8` : `131,201,613`	0.001	0.999	0.001
rs113414285 lBF = `0` Chr`8` : `24,395,263`	0.001	0.999	0.001
rs4128527 lBF = `0` Chr`8` : `72,682,693`	0.001	0.999	0.001
rs189590409 lBF = `0` Chr`8` : `114,727,602`	0.001	0.999	0.001
rs144222594 lBF = `0` Chr`8` : `12,931,504`	0.001	0.999	0.001
rs116129203 lBF = `0` Chr`8` : `6,779,323`	0.001	0.999	0.001
rs192074192 lBF = `0` Chr`8` : `73,025,833`	0.001	0.999	0.001
rs11989122 lBF = `0` Chr`8` : `118,827,839`	0.001	0.999	0.001
rs138094162 lBF = `0` Chr`8` : `6,489,568`	0.001	0.999	0.001
rs111754512 lBF = `0` Chr`8` : `24,400,648`	0.001	0.999	0.001
rs147852159 lBF = `0` Chr`8` : `146,171,164`	0.001	0.999	0.001
rs150435906 lBF = `0` Chr`8` : `66,864,338`	0.001	0.999	0.001
rs201734206 lBF = `0` Chr`8` : `73,984,100`	0.001	0.999	0.001
rs188858915 lBF = `0` Chr`8` : `6,494,833`	0.001	0.999	0.001
rs7460090 lBF = `0` Chr`8` : `57,194,163`	0.001	0.999	0.001
rs182838111 lBF = `0` Chr`8` : `67,889,470`	0.001	0.999	0.001
rs183191361 lBF = `0` Chr`8` : `76,083,247`	0.001	0.999	0.001
rs79781504 lBF = `0` Chr`8` : `84,750,057`	0.001	0.999	0.001
rs16902104 lBF = `0` Chr`8` : `128,340,908`	0.001	0.999	0.001
rs188809019 lBF = `0` Chr`8` : `129,286,235`	0.001	0.999	0.001
rs191935895 lBF = `0` Chr`8` : `5,267,311`	0.001	0.999	0.001
rs76547188 lBF = `0` Chr`8` : `21,978,372`	0.001	0.999	0.001
rs113660214 lBF = `0` Chr`8` : `977,436`	0.001	0.999	0.001
rs114258913 lBF = `0` Chr`8` : `93,525,403`	0.001	0.999	0.001
rs182387400 lBF = `0` Chr`8` : `25,129,708`	0.001	0.999	0.001
rs182302106 lBF = `0` Chr`8` : `1,455,175`	0.001	0.999	0.001
rs147851892 lBF = `0` Chr`8` : `24,234,355`	0.001	0.999	0.001
rs141395649 lBF = `0` Chr`8` : `6,498,690`	0.001	0.999	0.001
rs114252942 lBF = `0` Chr`8` : `6,202,964`	0.001	0.999	0.001
rs116041037 lBF = `0` Chr`8` : `128,131,809`	0.001	0.999	0.001
rs75455452 lBF = `0` Chr`8` : `72,991,580`	0.001	0.999	0.001
rs192316701 lBF = `0` Chr`8` : `1,456,068`	0.001	0.999	0.001
rs1845529 lBF = `0` Chr`8` : `116,163,863`	0.001	0.999	0.001
rs143335239 lBF = `0` Chr`8` : `6,500,809`	0.001	0.999	0.001
rs192994403 lBF = `0` Chr`8` : `76,211,333`	0.001	0.999	0.001
rs73313124 lBF = `0` Chr`8` : `110,478,822`	0.001	0.999	0.001
rs144424757 lBF = `0` Chr`8` : `12,929,793`	0.001	0.999	0.001
rs187636186 lBF = `0` Chr`8` : `73,002,468`	0.001	0.999	0.001
rs11986011 lBF = `0` Chr`8` : `127,332,657`	0.001	0.999	0.001
rs191631123 lBF = `0` Chr`8` : `32,443,704`	0.001	0.999	0.001
rs7015622 lBF = `-0.00005111` Chr`8` : `83,903,814`	0.001	0.999	0.000
rs12542677 lBF = `-0.00007086` Chr`8` : `56,168,059`	0.001	0.999	0.000
rs16904316 lBF = `-0.00010131` Chr`8` : `131,617,850`	0.001	0.999	0.000
rs183529902 lBF = `-0.0001389` Chr`8` : `35,880,032`	0.001	0.999	0.000
rs268 lBF = `1.6212` Chr`8` : `19,813,529`	0.001	0.999	0.000
rs4873403 lBF = `0.00168804` Chr`8` : `50,974,319`	0.001	0.999	0.000
rs4875284 lBF = `-0.00037851` Chr`8` : `3,978,130`	0.000	0.999	0.001
rs113367091 lBF = `-0.00039836` Chr`8` : `12,892,858`	0.001	0.999	0.000
rs151198427 lBF = `-0.00042403` Chr`8` : `68,351,787`	0.000	0.999	0.001
rs141088253 lBF = `-0.00045682` Chr`8` : `5,284,296`	0.001	0.999	0.000
rs186046079 lBF = `-0.00055881` Chr`8` : `6,468,714`	0.000	0.999	0.000
rs978152 lBF = `-0.104064` Chr`8` : `133,369,094`	0.000	0.999	0.001
rs17250031 lBF = `1.14225` Chr`8` : `75,077,959`	0.001	0.999	0.000
rs4397449 lBF = `-0.00020679` Chr`8` : `90,342,186`	0.000	0.999	0.000
rs78714084 lBF = `-0.0788769` Chr`8` : `89,031,066`	0.001	0.999	0.000
rs80029792 lBF = `0.150517` Chr`8` : `134,781,276`	0.000	0.999	0.001
rs10429371 lBF = `0.00079949` Chr`8` : `89,993,488`	0.001	0.999	0.000
rs16887217 lBF = `-0.00173689` Chr`8` : `38,004,425`	0.001	0.999	0.000
rs141603042 lBF = `-0.0388137` Chr`8` : `102,667,367`	0.000	0.999	0.001
rs7017914 lBF = `-0.0981629` Chr`8` : `71,591,203`	0.001	0.999	0.000
rs61496269 lBF = `-0.00255788` Chr`8` : `139,608,718`	0.001	0.999	0.000
rs16902460 lBF = `-0.00184885` Chr`8` : `128,920,197`	0.000	0.999	0.000
rs6469488 lBF = `-0.0286294` Chr`8` : `114,885,432`	0.001	0.999	0.000
rs6577655 lBF = `-0.0998599` Chr`8` : `135,593,725`	0.000	0.999	0.001
rs74566133 lBF = `0.124231` Chr`8` : `134,778,342`	0.000	0.999	0.001
rs59294057 lBF = `0.00031378` Chr`8` : `21,506,668`	0.000	0.999	0.000
rs6998277 lBF = `-0.161013` Chr`8` : `103,639,941`	0.001	0.999	0.000
rs11994034 lBF = `-0.00227443` Chr`8` : `73,070,735`	0.000	0.999	0.000
rs16938910 lBF = `-0.00335615` Chr`8` : `75,373,948`	0.000	0.999	0.000
rs185206099 lBF = `-0.0101661` Chr`8` : `6,477,298`	0.000	0.999	0.000
rs77609452 lBF = `-0.016984` Chr`8` : `26,312,097`	0.000	0.999	0.001
rs12680546 lBF = `-0.186143` Chr`8` : `136,871,739`	0.001	0.999	0.000
rs75609241 lBF = `0.111133` Chr`8` : `29,082,285`	0.001	0.999	0.000
rs116951791 lBF = `-0.0128998` Chr`8` : `93,219,721`	0.001	0.999	0.000
rs78894544 lBF = `0.0260822` Chr`8` : `138,323,083`	0.000	0.999	0.001
rs6473015 lBF = `0.014976` Chr`8` : `78,178,485`	0.001	0.999	0.000
rs16876083 lBF = `0.0108311` Chr`8` : `29,716,261`	0.000	0.999	0.000
rs188420713 lBF = `0.00750812` Chr`8` : `37,134,189`	0.000	0.999	0.000
rs7828089 lBF = `-0.00890453` Chr`8` : `22,264,334`	0.001	0.999	0.000
rs1512268 lBF = `-0.146959` Chr`8` : `23,526,463`	0.001	0.999	0.000
rs117405208 lBF = `0.0355189` Chr`8` : `134,967,408`	0.000	0.999	0.001
rs6601606 lBF = `-0.0241118` Chr`8` : `11,638,244`	0.000	0.999	0.001
rs7009219 lBF = `-0.0876723` Chr`8` : `53,214,265`	0.001	0.999	0.000
rs1512268 lBF = `-0.148546` Chr`8` : `23,526,463`	0.000	0.999	0.001
rs903027 lBF = `-0.152412` Chr`8` : `62,409,428`	0.001	0.999	0.000
rs78586881 lBF = `0.0766381` Chr`8` : `37,144,739`	0.001	0.999	0.000
rs17150703 lBF = `-0.0271379` Chr`8` : `9,745,798`	0.001	0.999	0.000
rs17687067 lBF = `-0.0934897` Chr`8` : `17,036,201`	0.001	0.999	0.000
rs630662 lBF = `0.220511` Chr`8` : `108,972,298`	0.000	0.999	0.001
rs7823724 lBF = `-0.026309` Chr`8` : `141,404,329`	0.001	0.999	0.000
rs56156301 lBF = `-0.0599644` Chr`8` : `104,147,804`	0.001	0.999	0.000
rs140707667 lBF = `0.0245574` Chr`8` : `84,028,528`	0.000	0.999	0.000
rs118061259 lBF = `-0.00520556` Chr`8` : `107,828,078`	0.000	0.999	0.000
rs142014203 lBF = `-0.00818973` Chr`8` : `63,258,917`	0.001	0.999	0.000
rs34975555 lBF = `-0.0368748` Chr`8` : `17,858,297`	0.001	0.999	0.000
rs310272 lBF = `-0.15772` Chr`8` : `23,643,489`	0.001	0.999	0.000
rs2657195 lBF = `-0.212657` Chr`8` : `92,559,915`	0.001	0.999	0.000
rs183826639 lBF = `0.00781219` Chr`8` : `76,817,264`	0.001	0.999	0.000
rs184060364 lBF = `0.0208941` Chr`8` : `84,120,968`	0.000	0.999	0.000
rs112767144 lBF = `0.00042324` Chr`8` : `134,263,916`	0.001	0.999	0.000
rs13267838 lBF = `-0.00525003` Chr`8` : `25,196,710`	0.000	0.999	0.000
rs140355816 lBF = `-0.0267756` Chr`8` : `117,574,515`	0.001	0.999	0.000
rs56292044 lBF = `-0.196514` Chr`8` : `138,776,547`	0.000	0.999	0.001
rs9772809 lBF = `0.12508` Chr`8` : `42,658,181`	0.001	0.999	0.000
rs284489 lBF = `-0.196107` Chr`8` : `105,958,020`	0.000	0.999	0.001
rs2048656 lBF = `4.07441` Chr`8` : `9,644,659`	0.001	0.999	0.000
rs75835816 lBF = `0.162558` Chr`8` : `19,885,513`	0.001	0.999	0.000
rs11774682 lBF = `0.00676604` Chr`8` : `31,034,275`	0.000	0.999	0.001
rs4875598 lBF = `-0.148467` Chr`8` : `5,461,753`	0.000	0.999	0.001
rs2163950 lBF = `0.0286828` Chr`8` : `130,597,585`	0.000	0.999	0.000
rs830478 lBF = `-0.00334354` Chr`8` : `73,372,875`	0.001	0.999	0.000
rs6472235 lBF = `-0.121796` Chr`8` : `66,822,030`	0.000	0.999	0.001
rs117297586 lBF = `0.0594969` Chr`8` : `50,205,976`	0.000	0.999	0.001
rs6586977 lBF = `-0.0151889` Chr`8` : `21,156,593`	0.000	0.999	0.000
rs79512063 lBF = `-0.00476336` Chr`8` : `89,533,747`	0.001	0.999	0.000
rs150488832 lBF = `-0.0166737` Chr`8` : `36,201,248`	0.000	0.999	0.000
rs10957961 lBF = `-0.0319862` Chr`8` : `81,031,822`	0.001	0.999	0.000
rs10095849 lBF = `-0.115005` Chr`8` : `39,408,586`	0.001	0.999	0.000
rs61134957 lBF = `0.0189233` Chr`8` : `92,599,003`	0.000	0.999	0.000
rs10503253 lBF = `-0.122738` Chr`8` : `4,180,844`	0.001	0.999	0.000
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rs2081687 lBF = `9.75619` Chr`8` : `59,388,565`	0.000	1.000	0.000
rs643955 lBF = `4.47288` Chr`8` : `9,891,254`	0.000	1.000	0.000
rs6984305 lBF = `0.754948` Chr`8` : `9,178,268`	0.000	1.000	0.000
rs6990042 lBF = `0.0418607` Chr`8` : `14,173,974`	0.000	1.000	0.000
rs7815327 lBF = `0.00617421` Chr`8` : `135,055,503`	0.000	1.000	0.000
rs7828135 lBF = `-0.00146642` Chr`8` : `81,058,819`	0.000	1.000	0.000
rs1481757 lBF = `-0.00951421` Chr`8` : `31,967,958`	0.000	1.000	0.000
rs117926607 lBF = `-0.0232138` Chr`8` : `55,468,849`	0.000	1.000	0.000
rs62522179 lBF = `-0.038973` Chr`8` : `142,154,696`	0.000	1.000	0.000
rs35868637 lBF = `-0.042221` Chr`8` : `94,743,876`	0.000	1.000	0.000
rs117628011 lBF = `-0.0448582` Chr`8` : `76,319,166`	0.000	1.000	0.000
rs77583023 lBF = `-0.0513037` Chr`8` : `46,946,626`	0.000	1.000	0.000
rs4557697 lBF = `-0.0603882` Chr`8` : `63,843,631`	0.000	1.000	0.000
rs3105169 lBF = `-0.0685043` Chr`8` : `100,495,639`	0.000	1.000	0.000
rs76794758 lBF = `-0.0693133` Chr`8` : `47,052,818`	0.000	1.000	0.000
rs1487141 lBF = `-0.0764084` Chr`8` : `32,139,652`	0.000	1.000	0.000
rs13270892 lBF = `-0.0947303` Chr`8` : `20,497,183`	0.000	1.000	0.000
rs117880470 lBF = `-0.104866` Chr`8` : `6,933,373`	0.000	1.000	0.000
rs16909318 lBF = `-0.170047` Chr`8` : `82,445,224`	0.000	1.000	0.000
rs6468442 lBF = `-0.173623` Chr`8` : `37,686,749`	0.000	1.000	0.000
rs2608053 lBF = `-0.216285` Chr`8` : `129,075,832`	0.000	1.000	0.000
rs12545912 lBF = `0.860615` Chr`8` : `9,601,699`	0.000	1.000	0.000
rs117857023 lBF = `0.107914` Chr`8` : `10,675,065`	0.000	1.000	0.000
rs6989010 lBF = `0.0471225` Chr`8` : `12,772,755`	0.000	1.000	0.000
rs1460237 lBF = `-0.0101551` Chr`8` : `105,841,855`	0.000	1.000	0.000
rs72667712 lBF = `-0.0270318` Chr`8` : `71,579,910`	0.000	1.000	0.000
rs80054318 lBF = `-0.0289884` Chr`8` : `50,129,604`	0.000	1.000	0.000
rs16905439 lBF = `-0.0423316` Chr`8` : `136,989,204`	0.000	1.000	0.000
rs145959269 lBF = `-0.0432737` Chr`8` : `143,357,023`	0.000	1.000	0.000
rs116424300 lBF = `-0.048525` Chr`8` : `143,412,988`	0.000	1.000	0.000
rs1594829 lBF = `-0.0659598` Chr`8` : `26,206,077`	0.000	1.000	0.000
rs10504906 lBF = `-0.0765044` Chr`8` : `92,418,628`	0.000	1.000	0.000
rs11985561 lBF = `-0.0917981` Chr`8` : `3,452,262`	0.000	1.000	0.000
rs1909881 lBF = `-0.104571` Chr`8` : `96,515,888`	0.000	1.000	0.000
rs7816032 lBF = `-0.13669` Chr`8` : `19,786,891`	0.000	1.000	0.000
rs10875469 lBF = `-0.156564` Chr`8` : `142,333,425`	0.000	1.000	0.000
rs7833986 lBF = `-0.172226` Chr`8` : `57,100,149`	0.000	1.000	0.000
rs4732812 lBF = `-0.201896` Chr`8` : `27,923,388`	0.000	1.000	0.000
rs10091038 lBF = `-0.202886` Chr`8` : `29,360,305`	0.000	1.000	0.000
rs9297994 lBF = `9.34305` Chr`8` : `59,392,324`	0.000	1.000	0.000
rs4738684 lBF = `9.15998` Chr`8` : `59,393,273`	0.000	1.000	0.000
rs12541491 lBF = `3.42788` Chr`8` : `10,250,048`	0.000	1.000	0.000
rs76308827 lBF = `0.0739283` Chr`8` : `80,264,727`	0.000	1.000	0.000
rs73225862 lBF = `0.0556736` Chr`8` : `22,050,584`	0.000	1.000	0.000
rs77822622 lBF = `0.00245263` Chr`8` : `57,929,662`	0.000	1.000	0.000
rs79816080 lBF = `-0.0214844` Chr`8` : `36,420,485`	0.000	1.000	0.000
rs28514585 lBF = `-0.0291456` Chr`8` : `129,636,084`	0.000	1.000	0.000
rs61729951 lBF = `-0.0334256` Chr`8` : `10,532,188`	0.000	1.000	0.000
rs74617895 lBF = `-0.0374659` Chr`8` : `3,646,688`	0.000	1.000	0.000
rs55705857 lBF = `-0.0376464` Chr`8` : `130,645,692`	0.000	1.000	0.000
rs187025166 lBF = `-0.0478993` Chr`8` : `61,592,878`	0.000	1.000	0.000
rs1992045 lBF = `-0.0613458` Chr`8` : `58,840,924`	0.000	1.000	0.000
rs117933211 lBF = `-0.0652457` Chr`8` : `47,243,611`	0.000	1.000	0.000
rs6988636 lBF = `-0.0688682` Chr`8` : `124,185,970`	0.000	1.000	0.000
rs11777116 lBF = `-0.0734275` Chr`8` : `24,044,301`	0.000	1.000	0.000
rs36056951 lBF = `-0.0780129` Chr`8` : `139,965,798`	0.000	1.000	0.000
rs74343026 lBF = `-0.0976297` Chr`8` : `126,258,883`	0.000	1.000	0.000
rs13255292 lBF = `-0.105007` Chr`8` : `129,076,573`	0.000	1.000	0.000
rs1375785 lBF = `-0.105048` Chr`8` : `83,991,231`	0.000	1.000	0.000
rs10503733 lBF = `-0.14824` Chr`8` : `23,534,018`	0.000	1.000	0.000
rs3864663 lBF = `-0.154042` Chr`8` : `78,680,349`	0.000	1.000	0.000
rs7814403 lBF = `-0.169082` Chr`8` : `36,459,454`	0.000	1.000	0.000
rs28455997 lBF = `-0.175467` Chr`8` : `3,076,959`	0.000	1.000	0.000
rs1461729 lBF = `1.91121` Chr`8` : `9,187,242`	0.000	1.000	0.000
rs2126259 lBF = `1.7955` Chr`8` : `9,185,146`	0.000	1.000	0.000
rs10106298 lBF = `0.37286` Chr`8` : `103,688,381`	0.000	1.000	0.000
rs111703385 lBF = `0.10207` Chr`8` : `8,499,516`	0.000	1.000	0.000
rs73199941 lBF = `0.0688604` Chr`8` : `18,573,919`	0.000	1.000	0.000
rs7823498 lBF = `0.0622171` Chr`8` : `32,403,573`	0.000	1.000	0.000
rs4739066 lBF = `0.0584558` Chr`8` : `64,104,092`	0.000	1.000	0.000
rs1875714 lBF = `0.042004` Chr`8` : `68,427,547`	0.000	1.000	0.000
rs75583295 lBF = `0.00980577` Chr`8` : `63,596,650`	0.000	1.000	0.000
rs17077154 lBF = `0.00174671` Chr`8` : `6,351,252`	0.000	1.000	0.000
rs118149821 lBF = `-0.0216763` Chr`8` : `85,276,067`	0.000	1.000	0.000
rs73204665 lBF = `-0.0286938` Chr`8` : `9,621,236`	0.000	1.000	0.000
rs150639459 lBF = `-0.0306524` Chr`8` : `18,804,686`	0.000	1.000	0.000
rs278541 lBF = `-0.0354795` Chr`8` : `94,222,945`	0.000	1.000	0.000
rs4437673 lBF = `-0.0404235` Chr`8` : `6,758,698`	0.000	1.000	0.000
rs117025875 lBF = `-0.051051` Chr`8` : `6,999,135`	0.000	1.000	0.000
rs7003257 lBF = `-0.0610526` Chr`8` : `68,613,390`	0.000	1.000	0.000
rs2020921 lBF = `-0.0629484` Chr`8` : `42,044,965`	0.000	1.000	0.000
rs9918841 lBF = `-0.0629745` Chr`8` : `91,193,959`	0.000	1.000	0.000
rs2514805 lBF = `-0.0689276` Chr`8` : `95,167,247`	0.000	1.000	0.000
rs1393902 lBF = `-0.0723918` Chr`8` : `68,421,565`	0.000	1.000	0.000
rs80301223 lBF = `-0.0746133` Chr`8` : `119,648,160`	0.000	1.000	0.000
rs10113221 lBF = `-0.0791586` Chr`8` : `3,743,704`	0.000	1.000	0.000
rs4590408 lBF = `-0.0868955` Chr`8` : `96,106,037`	0.000	1.000	0.000
rs6986718 lBF = `-0.0903532` Chr`8` : `121,635,396`	0.000	1.000	0.000
rs7822232 lBF = `-0.118553` Chr`8` : `145,145,687`	0.000	1.000	0.000
rs2860223 lBF = `-0.120378` Chr`8` : `134,668,677`	0.000	1.000	0.000
rs6558295 lBF = `-0.12109` Chr`8` : `145,139,522`	0.000	1.000	0.000
rs2437772 lBF = `-0.127985` Chr`8` : `97,512,977`	0.000	1.000	0.000
rs1027730 lBF = `-0.12994` Chr`8` : `94,085,539`	0.000	1.000	0.000
rs7829127 lBF = `-0.130126` Chr`8` : `40,726,394`	0.000	1.000	0.000
rs17749211 lBF = `0.76364` Chr`8` : `119,391,409`	0.000	1.000	0.000
rs6601299 lBF = `0.672602` Chr`8` : `9,184,691`	0.000	1.000	0.000
rs2460905 lBF = `0.444699` Chr`8` : `12,834,600`	0.000	1.000	0.000
rs11992011 lBF = `0.368441` Chr`8` : `4,263,916`	0.000	1.000	0.000
rs2128382 lBF = `0.13207` Chr`8` : `130,820,039`	0.000	1.000	0.000
rs7820838 lBF = `0.0579113` Chr`8` : `32,405,979`	0.000	1.000	0.000
rs921231 lBF = `0.0557041` Chr`8` : `92,360,396`	0.000	1.000	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Psychological/psychiatric problem
Nested terms	Alcohol dependency Opioid dependency Other substance abuse/dependency

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)