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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

Z08
Follow-up examination after treatment for malignant neoplasm
Parent term
Z00-Z13 Persons encountering health services for examination and investigation
Nested terms
Z08.0 Follow-up examination after surgery for malignant neoplasm
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
Z08.8 Follow-up examination after other treatment for malignant neoplasm
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
What are diagnostic terms?
Variant effects

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
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0.936 0.064 0.000
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0.721 0.279 0.000
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0.721 0.279 0.000
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0.693 0.307 0.000
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0.590 0.410 0.000
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0.564 0.436 0.000
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0.543 0.457 0.000
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0.521 0.479 0.000
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0.436 0.564 0.000
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0.411 0.589 0.000
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0.360 0.640 0.000
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0.352 0.648 0.000
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0.010 0.990 0.000
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0.010 0.990 0.000
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0.010 0.990 0.000
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0.010 0.990 0.000
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0.008 0.991 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 1.000 0.000
rs2834188 lBF = 0.979999   Chr21 : 34,689,253
0.000 1.000 0.000
rs170183 lBF = 0.520514   Chr21 : 37,848,334
0.000 1.000 0.000
rs1475911 lBF = 0.417681   Chr21 : 43,513,480
0.000 1.000 0.000
rs12483205 lBF = 0.304471   Chr21 : 38,740,824
0.000 1.000 0.000
rs11088226 lBF = 0.133914   Chr21 : 33,925,531
0.000 1.000 0.000
rs2827025 lBF = 0.114049   Chr21 : 23,144,602
0.000 1.000 0.000
rs9984896 lBF = 0.10604   Chr21 : 37,935,669
0.000 1.000 0.000
rs2226441 lBF = 0.0905002   Chr21 : 23,141,845
0.000 1.000 0.000
rs2832191 lBF = 0.0510475   Chr21 : 30,489,300
0.000 1.000 0.000
rs455804 lBF = 0.045419   Chr21 : 31,146,169
0.000 1.000 0.000
rs8127571 lBF = 0.0270023   Chr21 : 47,165,429
0.000 1.000 0.000
rs1892700 lBF = 0.0127465   Chr21 : 35,016,137
0.000 1.000 0.000
rs2838815 lBF = 0.0101966   Chr21 : 46,629,590
0.000 1.000 0.000
rs4148087 lBF = 0.00420442   Chr21 : 43,622,267
0.000 1.000 0.000
rs2055011 lBF = -0.00966066   Chr21 : 19,481,354
0.000 1.000 0.000
rs9305354 lBF = -0.0136521   Chr21 : 29,475,196
0.000 1.000 0.000
rs3788013 lBF = -0.0145564   Chr21 : 43,841,328
0.000 1.000 0.000
rs9980664 lBF = -0.021529   Chr21 : 34,734,510
0.000 1.000 0.000
rs9981861 lBF = -0.0218782   Chr21 : 41,415,044
0.000 1.000 0.000
rs8133949 lBF = -0.0229439   Chr21 : 43,421,114
0.000 1.000 0.000
rs1006899 lBF = -0.0285462   Chr21 : 15,845,052
0.000 1.000 0.000
rs7435 lBF = -0.0303864   Chr21 : 45,404,338
0.000 1.000 0.000
rs9976767 lBF = -0.0310062   Chr21 : 43,836,390
0.000 1.000 0.000
rs222158 lBF = -0.031462   Chr21 : 27,872,161
0.000 1.000 0.000
rs857551 lBF = -0.0317863   Chr21 : 44,829,992
0.000 1.000 0.000
rs580140 lBF = -0.0342   Chr21 : 32,817,507
0.000 1.000 0.000
rs2836770 lBF = -0.0345351   Chr21 : 40,314,704
0.000 1.000 0.000
rs2833607 lBF = -0.0373192   Chr21 : 33,381,040
0.000 1.000 0.000
rs11088872 lBF = -0.0384848   Chr21 : 23,033,104
0.000 1.000 0.000
rs721146 lBF = -0.0395564   Chr21 : 25,913,239
0.000 1.000 0.000
rs4293630 lBF = -0.0400741   Chr21 : 47,445,791
0.000 1.000 0.000
rs234714 lBF = -0.0455752   Chr21 : 44,488,033
0.000 1.000 0.000
rs2823819 lBF = -0.0470458   Chr21 : 17,828,291
0.000 1.000 0.000
rs7279441 lBF = -0.0493456   Chr21 : 24,198,815
0.000 1.000 0.000
rs2284553 lBF = -0.0519589   Chr21 : 34,776,695
0.000 1.000 0.000
rs2836425 lBF = -0.0525586   Chr21 : 39,838,825
0.000 1.000 0.000
rs4818184 lBF = -0.0557485   Chr21 : 42,202,431
0.000 1.000 0.000
rs2014791 lBF = -0.0600289   Chr21 : 23,145,950
0.000 1.000 0.000
rs2839627 lBF = -0.060477   Chr21 : 44,448,718
0.000 1.000 0.000
rs4819388 lBF = -0.0644269   Chr21 : 45,647,421
0.000 1.000 0.000
rs1789953 lBF = -0.0666517   Chr21 : 44,482,936
0.000 1.000 0.000
rs1888414 lBF = -0.0725322   Chr21 : 21,777,730
0.000 1.000 0.000
rs2826659 lBF = -0.0731005   Chr21 : 22,487,854
0.000 1.000 0.000
rs2823743 lBF = -0.0732029   Chr21 : 17,667,720
0.000 1.000 0.000
rs10854398 lBF = -0.0749246   Chr21 : 41,021,752
0.000 1.000 0.000
rs11910494 lBF = -0.0751362   Chr21 : 33,296,113
0.000 1.000 0.000
rs1452093 lBF = -0.0754478   Chr21 : 28,744,356
0.000 1.000 0.000
rs2851391 lBF = -0.0762453   Chr21 : 44,487,404
0.000 1.000 0.000
rs2834902 lBF = -0.0783849   Chr21 : 36,688,528
0.000 1.000 0.000
rs2828785 lBF = -0.0789514   Chr21 : 25,437,505
0.000 1.000 0.000
rs2839619 lBF = -0.0807418   Chr21 : 44,436,177
0.000 1.000 0.000
rs9977499 lBF = -0.0810928   Chr21 : 28,734,997
0.000 1.000 0.000
rs67900830 lBF = -0.0864751   Chr21 : 44,615,872
0.000 1.000 0.000
rs914189 lBF = -0.0869981   Chr21 : 43,710,909
0.000 1.000 0.000
rs9980603 lBF = -0.0946074   Chr21 : 41,886,583
0.000 1.000 0.000
rs2229741 lBF = -0.0954824   Chr21 : 16,340,289
0.000 1.000 0.000
rs13046373 lBF = -0.10425   Chr21 : 32,060,490
0.000 1.000 0.000
rs459482 lBF = -0.106186   Chr21 : 42,793,791
0.000 1.000 0.000
rs2837253 lBF = -0.10686   Chr21 : 41,221,256
0.000 1.000 0.000
rs1735884 lBF = -0.107025   Chr21 : 21,820,408
0.000 1.000 0.000
rs9982672 lBF = 11.9641   Chr21 : 35,657,043
0.000 1.000 0.000
rs2776353 lBF = 8.94721   Chr21 : 43,089,017
0.000 1.000 0.000
rs2242944 lBF = 7.22632   Chr21 : 40,465,178
0.000 1.000 0.000
rs2823093 lBF = 4.00125   Chr21 : 16,520,832
0.000 1.000 0.000
rs2834442 lBF = 2.718   Chr21 : 35,690,786
0.000 1.000 0.000
rs378108 lBF = 2.69278   Chr21 : 40,469,520
0.000 1.000 0.000
rs8133843 lBF = 2.07497   Chr21 : 36,738,242
0.000 1.000 0.000
rs1893592 lBF = 1.92566   Chr21 : 43,855,067
0.000 1.000 0.000
rs2836326 lBF = 0.711281   Chr21 : 39,721,764
0.000 1.000 0.000
rs11700808 lBF = 0.530252   Chr21 : 20,238,855
0.000 1.000 0.000
rs2828478 lBF = 0.508575   Chr21 : 25,105,211
0.000 1.000 0.000
rs62229266 lBF = 0.39816   Chr21 : 37,460,271
0.000 1.000 0.000
rs13048019 lBF = 0.203771   Chr21 : 32,918,294
0.000 1.000 0.000
rs4818225 lBF = 0.171213   Chr21 : 42,629,895
0.000 1.000 0.000
rs2205299 lBF = 0.129349   Chr21 : 18,206,630
0.000 1.000 0.000
rs914187 lBF = 0.12414   Chr21 : 42,619,749
0.000 1.000 0.000
rs743446 lBF = 0.0974998   Chr21 : 40,056,423
0.000 1.000 0.000
rs1041449 lBF = 0.0766488   Chr21 : 42,901,421
0.000 1.000 0.000
rs3787751 lBF = 0.0508496   Chr21 : 38,160,163
0.000 1.000 0.000
rs6517368 lBF = 0.00099417   Chr21 : 38,007,943
0.000 1.000 0.000
rs2839186 lBF = -0.00779405   Chr21 : 47,690,068
0.000 1.000 0.000
rs234709 lBF = -0.0381838   Chr21 : 44,486,964
0.000 1.000 0.000
rs2833693 lBF = -0.0392987   Chr21 : 33,552,512
0.000 1.000 0.000
rs4817775 lBF = -0.04216   Chr21 : 37,485,062
0.000 1.000 0.000
rs6517329 lBF = -0.0517081   Chr21 : 37,481,477
0.000 1.000 0.000
rs220262 lBF = -0.0546408   Chr21 : 43,482,046
0.000 1.000 0.000
rs8129913 lBF = -0.0599569   Chr21 : 27,064,339
0.000 1.000 0.000
rs2823962 lBF = -0.0606502   Chr21 : 18,046,232
0.000 1.000 0.000
rs2823357 lBF = -0.0652705   Chr21 : 16,914,905
0.000 1.000 0.000
rs2833522 lBF = -0.0667896   Chr21 : 33,179,371
0.000 1.000 0.000
rs2834655 lBF = -0.0675413   Chr21 : 36,238,507
0.000 1.000 0.000
rs7279297 lBF = -0.0697537   Chr21 : 43,227,915
0.000 1.000 0.000
rs614092 lBF = -0.0733539   Chr21 : 29,182,773
0.000 1.000 0.000
rs2826891 lBF = -0.0771127   Chr21 : 22,910,116
0.000 1.000 0.000
rs881827 lBF = -0.0773203   Chr21 : 48,019,868
0.000 1.000 0.000
rs9975851 lBF = -0.0786483   Chr21 : 27,716,654
0.000 1.000 0.000
rs9977018 lBF = -0.0792935   Chr21 : 43,036,969
0.000 1.000 0.000
rs234720 lBF = -0.0839953   Chr21 : 44,445,292
0.000 1.000 0.000
rs2828520 lBF = -0.0847883   Chr21 : 25,143,119
0.000 1.000 0.000
rs9305556 lBF = -0.0861211   Chr21 : 36,014,908
0.000 1.000 0.000
rs2827312 lBF = -0.0971242   Chr21 : 23,631,676
0.000 1.000 0.000
rs425215 lBF = -0.100826   Chr21 : 43,707,101
0.000 1.000 0.000
rs4816890 lBF = -0.104407   Chr21 : 24,420,502
0.000 1.000 0.000
rs372883 lBF = -0.112087   Chr21 : 30,717,737
0.000 1.000 0.000
rs2823615 lBF = -0.116722   Chr21 : 17,483,133
0.000 1.000 0.000
rs2410182 lBF = -0.121619   Chr21 : 41,180,076
0.000 1.000 0.000

This table lists the top 335 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0105
log Bayes Factor = 23.0031
contains 2 variants
1.0000
Cluster X0289
log Bayes Factor = 60.4564
contains 1 variants
0.6800
Cluster X0333
log Bayes Factor = 38.671
contains 2 variants
0.3361
Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.1079
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
1.0000
Cluster X0318
log Bayes Factor = 44.5459
contains 2 variants
1.0000
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
1.0000
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.9999
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.9999
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.9999
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.9998
Cluster X0244
log Bayes Factor = 122.647
contains 5 variants
0.9989
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.9960
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.9929
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.9928
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.9897
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.9841
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.9828
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.9823
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.9815
Cluster X0315
log Bayes Factor = 42.686
contains 2 variants
0.9722
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.9707
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.9659
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.9581
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.9549
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.9541
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.9275
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.9167
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.9066
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.9046
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.9042
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.9013
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.8937
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.8604
Cluster X0267
log Bayes Factor = 92.4806
contains 5 variants
0.8526
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.8493
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.8152
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.8107
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.8060
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.7652
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.7456
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.7382
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.7056
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.6878
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.6865
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.6666
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.6011
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.5955
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.5771
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.5492
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.4950
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.4537
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.4518
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.4311
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.4212
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.4073
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.3777
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.3576
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.3339
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.2818
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.2745
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.2605
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.2578
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.2472
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.2399
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.2135
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.2113
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.2054
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.1883
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.1783
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.1782
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.1767
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.1679
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.1649
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.1606
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.1543
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.1484
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.1405
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.1354
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.1322
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.1189
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.1135
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.1079
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.1069
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.1068
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.1065
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.1057
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.1045
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.0895
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.0851
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.0840
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.0817
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.0804
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.0754
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.0658
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.0637
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.0623
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.0605
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.0565
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.0527
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.0507
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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