TreeWAS – [I25.0] Atherosclerotic cardiovascular disease, so described

TreeWAS

Variant clusters

Hospitalization Episode Statistics (HES)

Genetic variants: 36,212

Diagnostic terms: × 19,155

Association results: = 693,640,860

Self-Reported Statistics (SRS)

Genetic variants: 28,458

Diagnostic terms: × 474

Association results: = 13,489,092

Frequently Asked Questions

Variant effects

Click on a variant to see its association results.

Download this figure in format

Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs17750460 lBF = `8.95898` Chr`21` : `30,745,615`	0.779	0.221	0.000
rs76287751 lBF = `15.4167` Chr`21` : `22,696,657`	0.717	0.283	0.000
rs74276156 lBF = `14.6764` Chr`21` : `37,842,165`	0.714	0.286	0.000
rs17744121 lBF = `5.69352` Chr`21` : `30,713,598`	0.714	0.286	0.000
rs76276670 lBF = `38.5052` Chr`21` : `30,505,980`	0.710	0.290	0.000
rs116990435 lBF = `16.0291` Chr`21` : `42,048,274`	0.701	0.299	0.000
rs113512172 lBF = `16.4938` Chr`21` : `32,718,685`	0.686	0.313	0.000
rs117903119 lBF = `9.06456` Chr`21` : `46,716,223`	0.684	0.316	0.000
rs7275212 lBF = `2.94756` Chr`21` : `39,852,551`	0.650	0.350	0.000
rs112308695 lBF = `21.2781` Chr`21` : `18,297,682`	0.602	0.398	0.000
rs79158929 lBF = `11.5913` Chr`21` : `35,682,958`	0.600	0.400	0.000
rs2834442 lBF = `2.718` Chr`21` : `35,690,786`	0.000	0.418	0.581
rs28451064 lBF = `42.9569` Chr`21` : `35,593,827`	0.573	0.427	0.000
rs9982672 lBF = `11.9641` Chr`21` : `35,657,043`	0.572	0.428	0.000
rs117887431 lBF = `13.1882` Chr`21` : `43,679,123`	0.555	0.445	0.000
rs9982601 lBF = `30.0006` Chr`21` : `35,599,128`	0.549	0.451	0.000
rs77292666 lBF = `7.58228` Chr`21` : `33,214,050`	0.539	0.461	0.000
rs62237594 lBF = `13.6107` Chr`21` : `41,465,664`	0.538	0.462	0.000
rs7276739 lBF = `7.64565` Chr`21` : `35,588,864`	0.534	0.466	0.000
rs2834431 lBF = `9.37156` Chr`21` : `35,644,228`	0.530	0.469	0.000
rs2834435 lBF = `11.0645` Chr`21` : `35,647,853`	0.527	0.473	0.000
rs9974878 lBF = `11.6455` Chr`21` : `35,642,446`	0.501	0.498	0.001
rs16991453 lBF = `12.1322` Chr`21` : `35,647,104`	0.500	0.499	0.001
rs9978142 lBF = `9.28145` Chr`21` : `35,652,239`	0.484	0.515	0.001
rs34484155 lBF = `9.50363` Chr`21` : `30,598,750`	0.483	0.517	0.000
rs117883435 lBF = `14.5495` Chr`21` : `27,788,794`	0.475	0.525	0.000
rs8131653 lBF = `1.50705` Chr`21` : `45,644,684`	0.351	0.649	0.000
rs62235665 lBF = `13.4781` Chr`21` : `41,534,335`	0.348	0.652	0.000
rs2826762 lBF = `7.61206` Chr`21` : `22,649,414`	0.298	0.702	0.000
rs869708 lBF = `14.092` Chr`21` : `46,434,954`	0.267	0.733	0.000
rs34308307 lBF = `7.33618` Chr`21` : `46,620,730`	0.215	0.785	0.000
rs1013063 lBF = `0.137067` Chr`21` : `35,698,390`	0.000	0.845	0.154
rs2832191 lBF = `0.0510475` Chr`21` : `30,489,300`	0.000	0.848	0.152
rs35724370 lBF = `16.3571` Chr`21` : `29,751,778`	0.131	0.869	0.000
rs10439884 lBF = `5.61662` Chr`21` : `10,971,951`	0.116	0.884	0.000
rs7283054 lBF = `1.12404` Chr`21` : `31,519,307`	0.093	0.906	0.000
rs16998084 lBF = `5.36261` Chr`21` : `42,471,628`	0.091	0.909	0.000
rs71319465 lBF = `15.9195` Chr`21` : `29,795,538`	0.064	0.935	0.000
rs17004598 lBF = `2.6091` Chr`21` : `45,078,556`	0.055	0.945	0.000
rs117069376 lBF = `9.48441` Chr`21` : `19,995,322`	0.029	0.971	0.000
rs10470209 lBF = `9.26221` Chr`21` : `20,110,007`	0.019	0.981	0.000
rs77851248 lBF = `21.7911` Chr`21` : `24,570,193`	0.019	0.981	0.000
rs111409535 lBF = `18.5218` Chr`21` : `30,790,390`	0.018	0.982	0.000
rs11088859 lBF = `14.6883` Chr`21` : `22,689,344`	0.014	0.986	0.000
rs77335750 lBF = `14.1372` Chr`21` : `37,579,120`	0.012	0.988	0.000
rs1899875 lBF = `15.3034` Chr`21` : `22,669,522`	0.010	0.990	0.000
rs113040104 lBF = `11.1608` Chr`21` : `24,412,633`	0.010	0.990	0.000
rs117589273 lBF = `5.16224` Chr`21` : `46,992,250`	0.009	0.991	0.000
rs74203920 lBF = `13.9618` Chr`21` : `45,714,294`	0.002	0.992	0.007
rs2834812 lBF = `1.53993` Chr`21` : `36,533,662`	0.008	0.992	0.000
rs2833197 lBF = `0.0509782` Chr`21` : `32,407,116`	0.006	0.993	0.001
rs117124364 lBF = `1.90172` Chr`21` : `34,369,761`	0.006	0.994	0.000
rs17229494 lBF = `5.20366` Chr`21` : `38,928,100`	0.006	0.994	0.000
rs16992204 lBF = `0.00737991` Chr`21` : `36,111,201`	0.005	0.995	0.000
rs7275460 lBF = `9.35732` Chr`21` : `41,447,058`	0.005	0.995	0.000
rs150097632 lBF = `16.4138` Chr`21` : `40,688,518`	0.004	0.995	0.000
rs7277179 lBF = `15.5832` Chr`21` : `30,758,760`	0.004	0.996	0.000
rs112643338 lBF = `0.293833` Chr`21` : `20,128,909`	0.003	0.996	0.000
rs201564772 lBF = `17.1704` Chr`21` : `17,774,632`	0.003	0.997	0.000
rs17272021 lBF = `15.6568` Chr`21` : `47,491,937`	0.003	0.997	0.000
rs1805128 lBF = `7.21284` Chr`21` : `35,821,680`	0.003	0.997	0.000
rs78211511 lBF = `0.00428967` Chr`21` : `17,562,284`	0.002	0.997	0.000
rs117270429 lBF = `18.3316` Chr`21` : `38,124,803`	0.002	0.998	0.000
rs914187 lBF = `0.12414` Chr`21` : `42,619,749`	0.002	0.998	0.000
rs77600076 lBF = `5.41577` Chr`21` : `19,531,442`	0.002	0.998	0.000
rs2836882 lBF = `15.1324` Chr`21` : `40,466,570`	0.002	0.998	0.000
rs2836883 lBF = `15.0723` Chr`21` : `40,466,744`	0.002	0.998	0.000
rs9808651 lBF = `14.9638` Chr`21` : `40,466,468`	0.002	0.998	0.000
rs4817986 lBF = `14.8584` Chr`21` : `40,465,512`	0.002	0.998	0.000
rs2836878 lBF = `14.682` Chr`21` : `40,465,534`	0.002	0.998	0.000
rs16999204 lBF = `7.39147` Chr`21` : `41,416,066`	0.001	0.999	0.000
rs79978308 lBF = `2.78083` Chr`21` : `41,020,545`	0.000	0.999	0.001
rs2242944 lBF = `7.22632` Chr`21` : `40,465,178`	0.001	0.999	0.000
rs16993221 lBF = `0.0000877` Chr`21` : `36,849,419`	0.001	0.999	0.000
rs189677472 lBF = `0` Chr`21` : `44,061,212`	0.001	0.999	0.001
rs142181472 lBF = `0` Chr`21` : `28,860,237`	0.001	0.999	0.001
rs75030518 lBF = `0` Chr`21` : `36,313,784`	0.001	0.999	0.001
rs142976294 lBF = `0` Chr`21` : `28,927,121`	0.001	0.999	0.001
rs141838403 lBF = `0` Chr`21` : `28,890,426`	0.001	0.999	0.001
rs142429672 lBF = `0` Chr`21` : `28,885,691`	0.001	0.999	0.001
rs139916902 lBF = `0` Chr`21` : `28,842,080`	0.001	0.999	0.001
rs186825689 lBF = `0` Chr`21` : `48,006,053`	0.001	0.999	0.001
rs139202427 lBF = `0` Chr`21` : `28,917,934`	0.001	0.999	0.001
rs111892515 lBF = `12.0702` Chr`21` : `23,392,906`	0.001	0.999	0.000
rs147130662 lBF = `0.00000084` Chr`21` : `28,830,255`	0.001	0.999	0.000
rs4148112 lBF = `-0.00001042` Chr`21` : `43,650,776`	0.001	0.999	0.000
rs8127967 lBF = `12.6191` Chr`21` : `21,763,036`	0.001	0.999	0.000
rs57126985 lBF = `-0.0092976` Chr`21` : `16,590,032`	0.000	0.999	0.001
rs9975325 lBF = `0.0364471` Chr`21` : `29,691,222`	0.001	0.999	0.000
rs451390 lBF = `-0.00398124` Chr`21` : `43,343,510`	0.000	0.999	0.001
rs378108 lBF = `2.69278` Chr`21` : `40,469,520`	0.000	0.999	0.001
rs9975851 lBF = `-0.0786483` Chr`21` : `27,716,654`	0.000	0.999	0.001
rs496300 lBF = `-0.04852` Chr`21` : `44,779,680`	0.000	0.999	0.001
rs118136136 lBF = `2.24787` Chr`21` : `35,274,965`	0.001	0.999	0.000
rs13046373 lBF = `-0.10425` Chr`21` : `32,060,490`	0.000	0.999	0.001
rs117802660 lBF = `15.852` Chr`21` : `27,198,954`	0.000	0.999	0.000
rs9984110 lBF = `5.56` Chr`21` : `31,447,366`	0.000	0.999	0.000
rs9976767 lBF = `-0.0310062` Chr`21` : `43,836,390`	0.000	0.999	0.001
rs3788013 lBF = `-0.0145564` Chr`21` : `43,841,328`	0.000	0.999	0.001
rs17227203 lBF = `5.66998` Chr`21` : `36,415,707`	0.000	0.999	0.000
rs2226441 lBF = `0.0905002` Chr`21` : `23,141,845`	0.001	0.999	0.000
rs2834215 lBF = `0.028894` Chr`21` : `34,796,886`	0.000	0.999	0.001
rs138755414 lBF = `0.01086` Chr`21` : `29,676,670`	0.000	0.999	0.000
rs2823752 lBF = `12.8636` Chr`21` : `17,717,125`	0.000	0.999	0.000
rs2823286 lBF = `0.148951` Chr`21` : `16,817,938`	0.000	0.999	0.000
rs9976946 lBF = `-0.00652189` Chr`21` : `36,208,062`	0.000	0.999	0.000
rs73185805 lBF = `2.62597` Chr`21` : `28,141,810`	0.000	1.000	0.000
rs62229266 lBF = `0.39816` Chr`21` : `37,460,271`	0.000	1.000	0.000
rs9977253 lBF = `-0.0446382` Chr`21` : `26,645,083`	0.000	1.000	0.000
rs2229741 lBF = `-0.0954824` Chr`21` : `16,340,289`	0.000	1.000	0.000
rs112591243 lBF = `0.325183` Chr`21` : `47,718,796`	0.000	1.000	0.000
rs2827025 lBF = `0.114049` Chr`21` : `23,144,602`	0.000	1.000	0.000
rs219776 lBF = `10.3337` Chr`21` : `37,834,835`	0.000	1.000	0.000
rs2268241 lBF = `0.401969` Chr`21` : `34,781,050`	0.000	1.000	0.000
rs580140 lBF = `-0.0342` Chr`21` : `32,817,507`	0.000	1.000	0.000
rs2829949 lBF = `8.60682` Chr`21` : `27,222,822`	0.000	1.000	0.000
rs2823455 lBF = `0.709971` Chr`21` : `17,069,166`	0.000	1.000	0.000
rs9979235 lBF = `0.031391` Chr`21` : `44,156,769`	0.000	1.000	0.000
rs112243387 lBF = `5.91351` Chr`21` : `37,649,206`	0.000	1.000	0.000
rs460214 lBF = `0.362655` Chr`21` : `40,006,081`	0.000	1.000	0.000
rs16994508 lBF = `0.200751` Chr`21` : `38,189,679`	0.000	1.000	0.000
rs2826340 lBF = `-0.00087214` Chr`21` : `21,885,302`	0.000	1.000	0.000
rs2409317 lBF = `-0.00559775` Chr`21` : `30,074,424`	0.000	1.000	0.000
rs62221577 lBF = `8.78053` Chr`21` : `33,164,508`	0.000	1.000	0.000
rs73336408 lBF = `8.76344` Chr`21` : `23,343,776`	0.000	1.000	0.000
rs11203203 lBF = `1.81255` Chr`21` : `43,836,186`	0.000	1.000	0.000
rs9982370 lBF = `0.04947` Chr`21` : `39,865,855`	0.000	1.000	0.000
rs2837857 lBF = `-0.0138956` Chr`21` : `42,216,955`	0.000	1.000	0.000
rs2832270 lBF = `-0.034884` Chr`21` : `30,594,532`	0.000	1.000	0.000
Affx-17521858 lBF = `7.5796` Chr`21` : `23,325,246`	0.000	1.000	0.000
rs219780 lBF = `6.95723` Chr`21` : `37,833,307`	0.000	1.000	0.000
rs55706246 lBF = `2.16084` Chr`21` : `35,595,637`	0.000	1.000	0.000
rs2834188 lBF = `0.979999` Chr`21` : `34,689,253`	0.000	1.000	0.000
rs57996174 lBF = `0.118538` Chr`21` : `34,837,048`	0.000	1.000	0.000
rs2154427 lBF = `0.0278154` Chr`21` : `34,168,573`	0.000	1.000	0.000
rs457352 lBF = `0.00520164` Chr`21` : `31,244,478`	0.000	1.000	0.000
rs220299 lBF = `0.00177075` Chr`21` : `43,502,762`	0.000	1.000	0.000
rs363512 lBF = `-0.00324042` Chr`21` : `31,050,817`	0.000	1.000	0.000
rs2839398 lBF = `-0.00482842` Chr`21` : `43,286,352`	0.000	1.000	0.000
rs1598848 lBF = `-0.0344972` Chr`21` : `28,946,276`	0.000	1.000	0.000
rs915832 lBF = `-0.0845599` Chr`21` : `43,275,495`	0.000	1.000	0.000
rs363598 lBF = `-0.102772` Chr`21` : `31,013,159`	0.000	1.000	0.000
rs9284510 lBF = `6.78234` Chr`21` : `47,557,074`	0.000	1.000	0.000
rs8134605 lBF = `-0.00482388` Chr`21` : `32,304,266`	0.000	1.000	0.000
rs3804024 lBF = `-0.0315963` Chr`21` : `41,993,707`	0.000	1.000	0.000
rs2014791 lBF = `-0.0600289` Chr`21` : `23,145,950`	0.000	1.000	0.000
rs1888414 lBF = `-0.0725322` Chr`21` : `21,777,730`	0.000	1.000	0.000
rs2826891 lBF = `-0.0771127` Chr`21` : `22,910,116`	0.000	1.000	0.000
rs34026679 lBF = `10.6117` Chr`21` : `27,248,814`	0.000	1.000	0.000
rs145672791 lBF = `0.0301724` Chr`21` : `14,750,023`	0.000	1.000	0.000
rs8127571 lBF = `0.0270023` Chr`21` : `47,165,429`	0.000	1.000	0.000
rs147991290 lBF = `0.0194318` Chr`21` : `34,088,470`	0.000	1.000	0.000
rs73199525 lBF = `-0.0135623` Chr`21` : `32,884,848`	0.000	1.000	0.000
rs9981861 lBF = `-0.0218782` Chr`21` : `41,415,044`	0.000	1.000	0.000
rs222158 lBF = `-0.031462` Chr`21` : `27,872,161`	0.000	1.000	0.000
rs78015114 lBF = `-0.0344031` Chr`21` : `20,312,612`	0.000	1.000	0.000
rs8129913 lBF = `-0.0599569` Chr`21` : `27,064,339`	0.000	1.000	0.000
rs614092 lBF = `-0.0733539` Chr`21` : `29,182,773`	0.000	1.000	0.000
rs4816890 lBF = `-0.104407` Chr`21` : `24,420,502`	0.000	1.000	0.000
rs9978888 lBF = `8.12132` Chr`21` : `18,002,476`	0.000	1.000	0.000
rs3827268 lBF = `5.10531` Chr`21` : `47,350,010`	0.000	1.000	0.000
rs4818048 lBF = `1.46255` Chr`21` : `40,908,952`	0.000	1.000	0.000
rs9979250 lBF = `0.727665` Chr`21` : `40,283,733`	0.000	1.000	0.000
rs170183 lBF = `0.520514` Chr`21` : `37,848,334`	0.000	1.000	0.000
rs441810 lBF = `0.234223` Chr`21` : `42,698,907`	0.000	1.000	0.000
rs16978810 lBF = `0.22043` Chr`21` : `47,488,332`	0.000	1.000	0.000
rs2075876 lBF = `0.143865` Chr`21` : `45,709,153`	0.000	1.000	0.000
rs79985863 lBF = `0.0973103` Chr`21` : `46,906,710`	0.000	1.000	0.000
rs17001239 lBF = `0.0773098` Chr`21` : `27,002,377`	0.000	1.000	0.000
rs16994935 lBF = `0.065828` Chr`21` : `38,671,418`	0.000	1.000	0.000
rs2192161 lBF = `0.0159299` Chr`21` : `15,681,994`	0.000	1.000	0.000
rs12483240 lBF = `0.00933915` Chr`21` : `26,829,777`	0.000	1.000	0.000
rs4148087 lBF = `0.00420442` Chr`21` : `43,622,267`	0.000	1.000	0.000
rs28456019 lBF = `-0.00475793` Chr`21` : `32,401,130`	0.000	1.000	0.000
rs9983044 lBF = `-0.0109852` Chr`21` : `36,416,332`	0.000	1.000	0.000
rs74795342 lBF = `-0.0164899` Chr`21` : `20,326,336`	0.000	1.000	0.000
rs2833991 lBF = `-0.0236283` Chr`21` : `34,262,687`	0.000	1.000	0.000
rs1006899 lBF = `-0.0285462` Chr`21` : `15,845,052`	0.000	1.000	0.000
rs78736162 lBF = `-0.0326747` Chr`21` : `42,740,488`	0.000	1.000	0.000
rs2833607 lBF = `-0.0373192` Chr`21` : `33,381,040`	0.000	1.000	0.000
rs2836425 lBF = `-0.0525586` Chr`21` : `39,838,825`	0.000	1.000	0.000
rs11910494 lBF = `-0.0751362` Chr`21` : `33,296,113`	0.000	1.000	0.000
rs2851391 lBF = `-0.0762453` Chr`21` : `44,487,404`	0.000	1.000	0.000
rs2834902 lBF = `-0.0783849` Chr`21` : `36,688,528`	0.000	1.000	0.000
rs2823615 lBF = `-0.116722` Chr`21` : `17,483,133`	0.000	1.000	0.000
rs74880545 lBF = `7.69301` Chr`21` : `29,997,493`	0.000	1.000	0.000
rs34835292 lBF = `6.28298` Chr`21` : `17,333,558`	0.000	1.000	0.000
rs1297265 lBF = `4.21826` Chr`21` : `16,817,051`	0.000	1.000	0.000
rs2823779 lBF = `1.55455` Chr`21` : `17,768,524`	0.000	1.000	0.000
rs45430 lBF = `0.51098` Chr`21` : `42,746,081`	0.000	1.000	0.000
rs8128234 lBF = `0.43771` Chr`21` : `36,470,865`	0.000	1.000	0.000
rs2833610 lBF = `0.160939` Chr`21` : `33,385,186`	0.000	1.000	0.000
rs2205299 lBF = `0.129349` Chr`21` : `18,206,630`	0.000	1.000	0.000
rs11700462 lBF = `0.0424012` Chr`21` : `38,817,812`	0.000	1.000	0.000
rs2833556 lBF = `0.00409185` Chr`21` : `33,285,300`	0.000	1.000	0.000
rs61550741 lBF = `-0.00079435` Chr`21` : `32,506,284`	0.000	1.000	0.000
rs1475591 lBF = `-0.00289356` Chr`21` : `32,440,540`	0.000	1.000	0.000
rs2822388 lBF = `-0.0162385` Chr`21` : `15,408,034`	0.000	1.000	0.000
rs457603 lBF = `-0.0251934` Chr`21` : `28,657,949`	0.000	1.000	0.000
rs4293630 lBF = `-0.0400741` Chr`21` : `47,445,791`	0.000	1.000	0.000
rs240444 lBF = `-0.0457575` Chr`21` : `11,002,011`	0.000	1.000	0.000
rs933117 lBF = `-0.0492371` Chr`21` : `31,100,797`	0.000	1.000	0.000
rs2823053 lBF = `-0.0542112` Chr`21` : `16,465,149`	0.000	1.000	0.000
rs2836823 lBF = `-0.0591825` Chr`21` : `40,380,249`	0.000	1.000	0.000
rs2839440 lBF = `-0.0607027` Chr`21` : `43,443,498`	0.000	1.000	0.000
rs2837828 lBF = `-0.0717683` Chr`21` : `42,174,960`	0.000	1.000	0.000
rs2828785 lBF = `-0.0789514` Chr`21` : `25,437,505`	0.000	1.000	0.000
rs67900830 lBF = `-0.0864751` Chr`21` : `44,615,872`	0.000	1.000	0.000
rs425215 lBF = `-0.100826` Chr`21` : `43,707,101`	0.000	1.000	0.000
rs7279238 lBF = `6.50081` Chr`21` : `43,092,206`	0.000	1.000	0.000
rs1297258 lBF = `4.38603` Chr`21` : `16,806,709`	0.000	1.000	0.000
rs1736135 lBF = `4.38257` Chr`21` : `16,805,220`	0.000	1.000	0.000
rs1893592 lBF = `1.92566` Chr`21` : `43,855,067`	0.000	1.000	0.000
rs2032314 lBF = `0.727556` Chr`21` : `35,354,523`	0.000	1.000	0.000
rs2836326 lBF = `0.711281` Chr`21` : `39,721,764`	0.000	1.000	0.000
rs6517656 lBF = `0.277616` Chr`21` : `42,583,738`	0.000	1.000	0.000
rs11088226 lBF = `0.133914` Chr`21` : `33,925,531`	0.000	1.000	0.000
rs1041449 lBF = `0.0766488` Chr`21` : `42,901,421`	0.000	1.000	0.000
rs2150410 lBF = `0.0583735` Chr`21` : `40,569,779`	0.000	1.000	0.000
rs242364 lBF = `0.0481487` Chr`21` : `28,890,132`	0.000	1.000	0.000
rs2823048 lBF = `0.00308356` Chr`21` : `16,462,268`	0.000	1.000	0.000
rs2822687 lBF = `-0.00244182` Chr`21` : `15,853,435`	0.000	1.000	0.000
rs2834629 lBF = `-0.0118618` Chr`21` : `36,125,818`	0.000	1.000	0.000
rs9305354 lBF = `-0.0136521` Chr`21` : `29,475,196`	0.000	1.000	0.000
rs2830840 lBF = `-0.0316523` Chr`21` : `28,665,347`	0.000	1.000	0.000
rs857551 lBF = `-0.0317863` Chr`21` : `44,829,992`	0.000	1.000	0.000
rs75884327 lBF = `-0.035947` Chr`21` : `40,491,320`	0.000	1.000	0.000
rs875125 lBF = `-0.0368883` Chr`21` : `46,129,686`	0.000	1.000	0.000
rs727333 lBF = `-0.0483779` Chr`21` : `41,702,947`	0.000	1.000	0.000
rs2014300 lBF = `-0.0544318` Chr`21` : `36,357,861`	0.000	1.000	0.000
rs10854398 lBF = `-0.0749246` Chr`21` : `41,021,752`	0.000	1.000	0.000
rs2838923 lBF = `-0.0840258` Chr`21` : `46,846,944`	0.000	1.000	0.000
rs1003719 lBF = `-0.0942392` Chr`21` : `38,491,095`	0.000	1.000	0.000
rs7281388 lBF = `6.02014` Chr`21` : `47,398,647`	0.000	1.000	0.000
rs1736020 lBF = `4.26685` Chr`21` : `16,812,552`	0.000	1.000	0.000
rs2823093 lBF = `4.00125` Chr`21` : `16,520,832`	0.000	1.000	0.000
rs8133843 lBF = `2.07497` Chr`21` : `36,738,242`	0.000	1.000	0.000
rs1475911 lBF = `0.417681` Chr`21` : `43,513,480`	0.000	1.000	0.000
rs12483205 lBF = `0.304471` Chr`21` : `38,740,824`	0.000	1.000	0.000
rs9984896 lBF = `0.10604` Chr`21` : `37,935,669`	0.000	1.000	0.000
rs743446 lBF = `0.0974998` Chr`21` : `40,056,423`	0.000	1.000	0.000
rs6586282 lBF = `0.0701648` Chr`21` : `44,478,497`	0.000	1.000	0.000
rs1735151 lBF = `0.0406235` Chr`21` : `41,123,301`	0.000	1.000	0.000
rs1734920 lBF = `0.00379406` Chr`21` : `41,344,911`	0.000	1.000	0.000
rs73194058 lBF = `0.00304808` Chr`21` : `34,764,288`	0.000	1.000	0.000
rs2055011 lBF = `-0.00966066` Chr`21` : `19,481,354`	0.000	1.000	0.000
rs9980664 lBF = `-0.021529` Chr`21` : `34,734,510`	0.000	1.000	0.000
rs8133949 lBF = `-0.0229439` Chr`21` : `43,421,114`	0.000	1.000	0.000
rs7435 lBF = `-0.0303864` Chr`21` : `45,404,338`	0.000	1.000	0.000
rs9305406 lBF = `-0.032338` Chr`21` : `31,386,243`	0.000	1.000	0.000
rs234709 lBF = `-0.0381838` Chr`21` : `44,486,964`	0.000	1.000	0.000
rs2823819 lBF = `-0.0470458` Chr`21` : `17,828,291`	0.000	1.000	0.000
rs7279441 lBF = `-0.0493456` Chr`21` : `24,198,815`	0.000	1.000	0.000
rs9984974 lBF = `-0.0498674` Chr`21` : `37,809,377`	0.000	1.000	0.000
rs220262 lBF = `-0.0546408` Chr`21` : `43,482,046`	0.000	1.000	0.000
rs2832077 lBF = `-0.0553533` Chr`21` : `30,141,021`	0.000	1.000	0.000
rs4818184 lBF = `-0.0557485` Chr`21` : `42,202,431`	0.000	1.000	0.000
rs2839627 lBF = `-0.060477` Chr`21` : `44,448,718`	0.000	1.000	0.000
rs458685 lBF = `-0.0625465` Chr`21` : `31,177,511`	0.000	1.000	0.000
rs2154490 lBF = `-0.0662055` Chr`21` : `30,915,962`	0.000	1.000	0.000
rs1789953 lBF = `-0.0666517` Chr`21` : `44,482,936`	0.000	1.000	0.000
rs2823743 lBF = `-0.0732029` Chr`21` : `17,667,720`	0.000	1.000	0.000
rs12483148 lBF = `-0.077018` Chr`21` : `37,013,621`	0.000	1.000	0.000
rs881827 lBF = `-0.0773203` Chr`21` : `48,019,868`	0.000	1.000	0.000
rs9977018 lBF = `-0.0792935` Chr`21` : `43,036,969`	0.000	1.000	0.000
rs914189 lBF = `-0.0869981` Chr`21` : `43,710,909`	0.000	1.000	0.000
rs459482 lBF = `-0.106186` Chr`21` : `42,793,791`	0.000	1.000	0.000
rs2776353 lBF = `8.94721` Chr`21` : `43,089,017`	0.000	1.000	0.000
rs2836974 lBF = `1.76446` Chr`21` : `40,663,181`	0.000	1.000	0.000
rs2835345 lBF = `1.75696` Chr`21` : `37,801,434`	0.000	1.000	0.000
rs2828478 lBF = `0.508575` Chr`21` : `25,105,211`	0.000	1.000	0.000
rs6517147 lBF = `0.281921` Chr`21` : `34,542,787`	0.000	1.000	0.000
rs13048019 lBF = `0.203771` Chr`21` : `32,918,294`	0.000	1.000	0.000
rs982274 lBF = `0.123226` Chr`21` : `19,479,731`	0.000	1.000	0.000
rs455804 lBF = `0.045419` Chr`21` : `31,146,169`	0.000	1.000	0.000
rs1892700 lBF = `0.0127465` Chr`21` : `35,016,137`	0.000	1.000	0.000
rs6517368 lBF = `0.00099417` Chr`21` : `38,007,943`	0.000	1.000	0.000
rs2837960 lBF = `-0.00220077` Chr`21` : `42,511,918`	0.000	1.000	0.000
rs643608 lBF = `-0.00745327` Chr`21` : `44,768,562`	0.000	1.000	0.000
rs2825388 lBF = `-0.0177098` Chr`21` : `20,536,649`	0.000	1.000	0.000
rs2833693 lBF = `-0.0392987` Chr`21` : `33,552,512`	0.000	1.000	0.000
rs721146 lBF = `-0.0395564` Chr`21` : `25,913,239`	0.000	1.000	0.000
rs234714 lBF = `-0.0455752` Chr`21` : `44,488,033`	0.000	1.000	0.000
rs2838088 lBF = `-0.0551434` Chr`21` : `43,092,201`	0.000	1.000	0.000
rs1547374 lBF = `-0.0571228` Chr`21` : `43,778,895`	0.000	1.000	0.000
rs4819388 lBF = `-0.0644269` Chr`21` : `45,647,421`	0.000	1.000	0.000
rs2823357 lBF = `-0.0652705` Chr`21` : `16,914,905`	0.000	1.000	0.000
rs7279297 lBF = `-0.0697537` Chr`21` : `43,227,915`	0.000	1.000	0.000
rs2826659 lBF = `-0.0731005` Chr`21` : `22,487,854`	0.000	1.000	0.000
rs727957 lBF = `-0.0780552` Chr`21` : `35,880,072`	0.000	1.000	0.000
rs9977499 lBF = `-0.0810928` Chr`21` : `28,734,997`	0.000	1.000	0.000
rs4819143 lBF = `-0.0830092` Chr`21` : `47,124,178`	0.000	1.000	0.000
rs8133932 lBF = `-0.0830158` Chr`21` : `47,211,085`	0.000	1.000	0.000
rs234720 lBF = `-0.0839953` Chr`21` : `44,445,292`	0.000	1.000	0.000
rs9305556 lBF = `-0.0861211` Chr`21` : `36,014,908`	0.000	1.000	0.000
rs2827312 lBF = `-0.0971242` Chr`21` : `23,631,676`	0.000	1.000	0.000
rs8127977 lBF = `-0.0978804` Chr`21` : `26,826,514`	0.000	1.000	0.000
rs1735884 lBF = `-0.107025` Chr`21` : `21,820,408`	0.000	1.000	0.000
rs2410182 lBF = `-0.121619` Chr`21` : `41,180,076`	0.000	1.000	0.000
rs2849691 lBF = `6.2942` Chr`21` : `43,086,070`	0.000	1.000	0.000
rs8127691 lBF = `1.52837` Chr`21` : `45,614,860`	0.000	1.000	0.000
rs762421 lBF = `1.4046` Chr`21` : `45,615,561`	0.000	1.000	0.000
rs2836950 lBF = `0.735886` Chr`21` : `40,604,429`	0.000	1.000	0.000
rs2838519 lBF = `0.725029` Chr`21` : `45,615,023`	0.000	1.000	0.000
rs11700808 lBF = `0.530252` Chr`21` : `20,238,855`	0.000	1.000	0.000
rs7282490 lBF = `0.498175` Chr`21` : `45,615,741`	0.000	1.000	0.000
rs2835810 lBF = `0.176405` Chr`21` : `38,932,778`	0.000	1.000	0.000
rs4818225 lBF = `0.171213` Chr`21` : `42,629,895`	0.000	1.000	0.000
rs3787751 lBF = `0.0508496` Chr`21` : `38,160,163`	0.000	1.000	0.000
rs1209950 lBF = `0.0382876` Chr`21` : `40,173,528`	0.000	1.000	0.000
rs2838815 lBF = `0.0101966` Chr`21` : `46,629,590`	0.000	1.000	0.000
rs2839186 lBF = `-0.00779405` Chr`21` : `47,690,068`	0.000	1.000	0.000
rs9305339 lBF = `-0.0168166` Chr`21` : `29,275,627`	0.000	1.000	0.000
rs427943 lBF = `-0.0176839` Chr`21` : `46,570,896`	0.000	1.000	0.000
rs2836770 lBF = `-0.0345351` Chr`21` : `40,314,704`	0.000	1.000	0.000
rs11088872 lBF = `-0.0384848` Chr`21` : `23,033,104`	0.000	1.000	0.000
rs4817775 lBF = `-0.04216` Chr`21` : `37,485,062`	0.000	1.000	0.000
rs6517329 lBF = `-0.0517081` Chr`21` : `37,481,477`	0.000	1.000	0.000
rs2284553 lBF = `-0.0519589` Chr`21` : `34,776,695`	0.000	1.000	0.000
rs2823962 lBF = `-0.0606502` Chr`21` : `18,046,232`	0.000	1.000	0.000
rs2833522 lBF = `-0.0667896` Chr`21` : `33,179,371`	0.000	1.000	0.000
rs2834655 lBF = `-0.0675413` Chr`21` : `36,238,507`	0.000	1.000	0.000
rs2298450 lBF = `-0.0708057` Chr`21` : `37,623,447`	0.000	1.000	0.000
rs1452093 lBF = `-0.0754478` Chr`21` : `28,744,356`	0.000	1.000	0.000
rs2839619 lBF = `-0.0807418` Chr`21` : `44,436,177`	0.000	1.000	0.000
rs2836751 lBF = `-0.0823765` Chr`21` : `40,290,959`	0.000	1.000	0.000
rs2836754 lBF = `-0.0832655` Chr`21` : `40,291,740`	0.000	1.000	0.000
rs2828520 lBF = `-0.0847883` Chr`21` : `25,143,119`	0.000	1.000	0.000
rs9980603 lBF = `-0.0946074` Chr`21` : `41,886,583`	0.000	1.000	0.000
rs9975691 lBF = `-0.0954731` Chr`21` : `14,928,355`	0.000	1.000	0.000
rs2837253 lBF = `-0.10686` Chr`21` : `41,221,256`	0.000	1.000	0.000
rs2830487 lBF = `-0.11195` Chr`21` : `28,146,189`	0.000	1.000	0.000
rs372883 lBF = `-0.112087` Chr`21` : `30,717,737`	0.000	1.000	0.000
rs11911275 lBF = `-0.119655` Chr`21` : `44,593,140`	0.000	1.000	0.000
rs7283316 lBF = `-0.136982` Chr`21` : `32,216,253`	0.000	1.000	0.000

This table lists the top 335 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0002

log Bayes Factor = 522.044

contains 22 variants

Cluster X0228

log Bayes Factor = 196.521

contains 11 variants

Cluster X0112

log Bayes Factor = 98.8923

contains 7 variants

Cluster X0199

log Bayes Factor = 350.038

contains 3 variants

Cluster X0335

log Bayes Factor = 12.3689

contains 1 variants

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

Cluster X0034

log Bayes Factor = 665.104

contains 16 variants

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

Cluster X0064

log Bayes Factor = 166.06

contains 10 variants

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

Cluster X0227

log Bayes Factor = 249.287

contains 11 variants

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

Cluster X0200

log Bayes Factor = 162.369

contains 2 variants

Cluster X0250

log Bayes Factor = 43.399

contains 4 variants

Cluster X0231

log Bayes Factor = 82.3185

contains 5 variants

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

Cluster X0204

log Bayes Factor = 169.796

contains 8 variants

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

Cluster X0294

log Bayes Factor = 25.2869

contains 2 variants

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

Cluster X0326

log Bayes Factor = 112.92

contains 5 variants

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

Cluster X0107

log Bayes Factor = 151.016

contains 1 variants

Cluster X0170

log Bayes Factor = 264.081

contains 11 variants

Cluster X0028

log Bayes Factor = 120.445

contains 7 variants

Cluster X0180

log Bayes Factor = 410.88

contains 15 variants

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

Cluster X0039

log Bayes Factor = 463.231

contains 17 variants

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

Cluster X0284

log Bayes Factor = 192.532

contains 9 variants

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

Cluster X0043

log Bayes Factor = 517.108

contains 20 variants

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

Cluster X0229

log Bayes Factor = 347.165

contains 13 variants

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

Cluster X0226

log Bayes Factor = 145.726

contains 8 variants

Cluster X0321

log Bayes Factor = 162.562

contains 1 variants

Cluster X0208

log Bayes Factor = 40.6733

contains 2 variants

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

Cluster X0307

log Bayes Factor = 826.86

contains 2 variants

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

Cluster X0104

log Bayes Factor = 122.44

contains 5 variants

Cluster X0297

log Bayes Factor = 63.8292

contains 4 variants

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

Cluster X0060

log Bayes Factor = 242.413

contains 5 variants

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

Cluster X0114

log Bayes Factor = 510.917

contains 25 variants

Cluster X0330

log Bayes Factor = 183.455

contains 2 variants

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

Cluster X0146

log Bayes Factor = 686.343

contains 22 variants

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

Cluster X0098

log Bayes Factor = 246.226

contains 8 variants

Cluster X0262

log Bayes Factor = 269.713

contains 9 variants

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

Cluster X0164

log Bayes Factor = 463.793

contains 16 variants

Cluster X0264

log Bayes Factor = 205.833

contains 10 variants

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

Cluster X0075

log Bayes Factor = 431.344

contains 16 variants

Cluster X0003

log Bayes Factor = 195.6

contains 8 variants

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

Cluster X0191

log Bayes Factor = 163.555

contains 8 variants

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

Cluster X0145

log Bayes Factor = 274.587

contains 11 variants

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.