TreeWAS – [I25.0] Atherosclerotic cardiovascular disease, so described

TreeWAS

Variant clusters

Hospitalization Episode Statistics (HES)

Genetic variants: 36,212

Diagnostic terms: × 19,155

Association results: = 693,640,860

Self-Reported Statistics (SRS)

Genetic variants: 28,458

Diagnostic terms: × 474

Association results: = 13,489,092

Frequently Asked Questions

Variant effects

Click on a variant to see its association results.

Download this figure in format

Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs117930276 lBF = `8.79467` Chr`14` : `68,864,686`	0.756	0.244	0.000
rs28929474 lBF = `54.4847` Chr`14` : `94,844,947`	0.000	0.283	0.717
rs112635299 lBF = `54.2277` Chr`14` : `94,838,142`	0.000	0.283	0.717
rs10690822 lBF = `15.0738` Chr`14` : `24,646,406`	0.717	0.283	0.000
rs72687020 lBF = `14.6249` Chr`14` : `44,923,657`	0.717	0.283	0.000
rs75842146 lBF = `12.2652` Chr`14` : `26,461,063`	0.717	0.283	0.000
rs112458284 lBF = `13.1757` Chr`14` : `94,672,731`	0.000	0.284	0.716
rs72720853 lBF = `18.1353` Chr`14` : `62,630,726`	0.716	0.284	0.000
rs117862559 lBF = `22.8961` Chr`14` : `40,013,534`	0.704	0.296	0.000
rs17393098 lBF = `26.5255` Chr`14` : `34,025,230`	0.703	0.296	0.000
rs118155371 lBF = `14.9536` Chr`14` : `49,874,673`	0.701	0.299	0.000
rs17094474 lBF = `8.18878` Chr`14` : `58,819,463`	0.700	0.300	0.000
rs117679538 lBF = `14.2819` Chr`14` : `91,668,581`	0.700	0.300	0.000
rs117486971 lBF = `14.5192` Chr`14` : `76,871,420`	0.693	0.307	0.000
rs78427738 lBF = `14.854` Chr`14` : `101,760,044`	0.691	0.309	0.000
rs118164726 lBF = `20.0312` Chr`14` : `59,013,798`	0.682	0.318	0.000
rs45505795 lBF = `15.9739` Chr`14` : `94,756,943`	0.000	0.319	0.681
rs117593613 lBF = `20.9111` Chr`14` : `88,296,569`	0.667	0.333	0.000
rs61734876 lBF = `12.131` Chr`14` : `20,874,411`	0.666	0.334	0.000
rs117531052 lBF = `28.3704` Chr`14` : `46,783,950`	0.653	0.347	0.000
rs112217762 lBF = `12.3992` Chr`14` : `91,635,649`	0.631	0.369	0.000
rs34803930 lBF = `21.1404` Chr`14` : `62,581,386`	0.620	0.380	0.000
rs10498345 lBF = `1.07994` Chr`14` : `39,020,505`	0.606	0.394	0.000
rs117822702 lBF = `13.8577` Chr`14` : `60,403,097`	0.596	0.403	0.000
rs80334718 lBF = `23.0437` Chr`14` : `33,998,519`	0.577	0.423	0.000
rs77306365 lBF = `14.2842` Chr`14` : `86,751,059`	0.534	0.466	0.000
rs118133890 lBF = `21.4584` Chr`14` : `86,871,489`	0.517	0.483	0.000
rs79534246 lBF = `4.3436` Chr`14` : `53,386,442`	0.492	0.508	0.000
rs117114876 lBF = `16.6508` Chr`14` : `73,422,219`	0.466	0.534	0.000
rs117420945 lBF = `15.4093` Chr`14` : `75,662,480`	0.430	0.570	0.000
rs117422606 lBF = `12.1156` Chr`14` : `40,206,769`	0.411	0.589	0.000
rs79120241 lBF = `12.9559` Chr`14` : `48,698,503`	0.398	0.602	0.000
rs17777854 lBF = `16.6024` Chr`14` : `89,610,698`	0.394	0.606	0.000
rs192549394 lBF = `1.61666` Chr`14` : `52,293,779`	0.373	0.627	0.000
rs192692653 lBF = `2.44667` Chr`14` : `52,384,486`	0.353	0.647	0.000
rs78564868 lBF = `15.4695` Chr`14` : `96,363,347`	0.315	0.685	0.000
rs72728293 lBF = `32.154` Chr`14` : `65,578,757`	0.307	0.693	0.000
rs117662109 lBF = `19.3722` Chr`14` : `47,236,919`	0.304	0.695	0.000
rs61280460 lBF = `1.0785` Chr`14` : `94,796,184`	0.000	0.709	0.291
rs116911364 lBF = `17.5103` Chr`14` : `93,276,446`	0.259	0.741	0.000
rs17116970 lBF = `6.59001` Chr`14` : `46,592,058`	0.253	0.747	0.000
rs191800091 lBF = `14.8331` Chr`14` : `27,245,961`	0.235	0.764	0.000
rs79903896 lBF = `14.376` Chr`14` : `31,222,143`	0.221	0.779	0.000
rs111974986 lBF = `6.05816` Chr`14` : `94,533,735`	0.001	0.793	0.206
rs75038438 lBF = `18.8448` Chr`14` : `60,996,166`	0.202	0.798	0.000
rs61988316 lBF = `17.5259` Chr`14` : `35,888,993`	0.180	0.820	0.000
rs2168211 lBF = `16.1589` Chr`14` : `31,000,608`	0.173	0.827	0.000
rs17768925 lBF = `15.6193` Chr`14` : `72,641,469`	0.154	0.846	0.000
rs186152940 lBF = `0.126532` Chr`14` : `46,476,984`	0.142	0.858	0.000
rs1026385 lBF = `13.205` Chr`14` : `69,786,063`	0.142	0.858	0.000
rs76984655 lBF = `7.79218` Chr`14` : `51,045,350`	0.125	0.874	0.000
rs3783782 lBF = `0.0923372` Chr`14` : `61,940,675`	0.000	0.877	0.123
rs117263911 lBF = `16.7712` Chr`14` : `30,929,126`	0.122	0.878	0.000
rs117626347 lBF = `17.0112` Chr`14` : `79,813,041`	0.119	0.881	0.000
rs3811319 lBF = `19.9487` Chr`14` : `22,482,497`	0.115	0.885	0.000
rs117669821 lBF = `20.5156` Chr`14` : `88,258,889`	0.104	0.896	0.000
rs41299205 lBF = `7.8381` Chr`14` : `91,581,272`	0.103	0.897	0.000
rs117176329 lBF = `15.0759` Chr`14` : `93,656,324`	0.099	0.901	0.000
rs72677598 lBF = `8.49063` Chr`14` : `23,078,904`	0.088	0.912	0.000
rs117123268 lBF = `19.5843` Chr`14` : `76,719,166`	0.083	0.917	0.000
rs80221072 lBF = `0.96065` Chr`14` : `33,795,591`	0.079	0.920	0.000
rs17104944 lBF = `5.05105` Chr`14` : `37,143,742`	0.078	0.922	0.000
rs7494275 lBF = `2.57294` Chr`14` : `56,231,800`	0.076	0.924	0.000
rs17176768 lBF = `11.8039` Chr`14` : `37,151,905`	0.075	0.925	0.000
rs73272823 lBF = `15.6671` Chr`14` : `66,292,820`	0.070	0.930	0.000
rs72698796 lBF = `18.4874` Chr`14` : `101,363,503`	0.070	0.930	0.000
rs150511909 lBF = `0.288513` Chr`14` : `97,908,686`	0.063	0.937	0.000
rs17690804 lBF = `12.2799` Chr`14` : `88,711,855`	0.058	0.942	0.000
rs118118740 lBF = `29.2075` Chr`14` : `102,482,939`	0.056	0.944	0.000
rs118006904 lBF = `18.7559` Chr`14` : `40,477,467`	0.052	0.948	0.000
rs78113488 lBF = `7.12858` Chr`14` : `49,543,462`	0.051	0.948	0.000
rs182491339 lBF = `0.10278` Chr`14` : `66,049,929`	0.047	0.953	0.000
rs12896812 lBF = `15.8059` Chr`14` : `104,324,496`	0.046	0.954	0.000
rs117487501 lBF = `16.2076` Chr`14` : `26,589,434`	0.032	0.968	0.000
rs55722931 lBF = `16.5782` Chr`14` : `23,586,795`	0.030	0.970	0.000
rs77176328 lBF = `15.521` Chr`14` : `71,370,689`	0.027	0.973	0.000
rs79733525 lBF = `15.1192` Chr`14` : `60,198,625`	0.026	0.974	0.000
rs117704155 lBF = `14.0485` Chr`14` : `37,850,007`	0.026	0.974	0.000
rs78652542 lBF = `13.5681` Chr`14` : `26,964,012`	0.025	0.975	0.000
rs11627967 lBF = `0.353752` Chr`14` : `33,769,912`	0.025	0.975	0.000
rs183755958 lBF = `0.0427294` Chr`14` : `52,307,478`	0.024	0.976	0.000
rs10142466 lBF = `0.172223` Chr`14` : `69,271,784`	0.000	0.976	0.024
rs77657273 lBF = `15.1219` Chr`14` : `35,139,957`	0.023	0.977	0.000
rs186116546 lBF = `0.0301833` Chr`14` : `65,986,176`	0.023	0.977	0.000
rs72726252 lBF = `21.4932` Chr`14` : `65,332,190`	0.022	0.978	0.000
rs12587252 lBF = `0.5067` Chr`14` : `81,405,922`	0.021	0.979	0.000
rs1092015 lBF = `1.59496` Chr`14` : `58,200,725`	0.000	0.979	0.021
rs117068537 lBF = `12.8587` Chr`14` : `70,832,113`	0.020	0.980	0.000
rs75466358 lBF = `21.4617` Chr`14` : `98,107,800`	0.019	0.981	0.000
rs61992823 lBF = `12.5724` Chr`14` : `43,247,586`	0.018	0.982	0.000
rs144560641 lBF = `4.48499` Chr`14` : `86,336,504`	0.018	0.982	0.000
rs1889721 lBF = `15.2322` Chr`14` : `57,778,179`	0.016	0.984	0.000
rs77209553 lBF = `15.841` Chr`14` : `80,155,113`	0.016	0.984	0.000
rs118081779 lBF = `8.84977` Chr`14` : `27,218,316`	0.014	0.985	0.000
rs117597017 lBF = `9.81246` Chr`14` : `56,885,357`	0.014	0.986	0.000
rs117161928 lBF = `6.02809` Chr`14` : `94,391,705`	0.014	0.986	0.000
rs10136659 lBF = `14.3641` Chr`14` : `65,377,610`	0.013	0.987	0.000
rs72718577 lBF = `10.2191` Chr`14` : `62,522,221`	0.013	0.987	0.000
rs118001455 lBF = `19.3426` Chr`14` : `27,939,522`	0.012	0.988	0.000
rs10498548 lBF = `16.7091` Chr`14` : `81,126,016`	0.012	0.988	0.000
rs3783863 lBF = `0.0157879` Chr`14` : `89,776,745`	0.000	0.988	0.012
rs58262369 lBF = `0.0229117` Chr`14` : `64,693,912`	0.011	0.988	0.000
rs77090488 lBF = `26.9855` Chr`14` : `84,959,799`	0.011	0.989	0.000
rs12589674 lBF = `5.86884` Chr`14` : `54,246,353`	0.011	0.989	0.000
rs17758321 lBF = `11.5799` Chr`14` : `79,928,225`	0.011	0.989	0.000
rs74635668 lBF = `12.4172` Chr`14` : `54,188,200`	0.010	0.990	0.000
rs116352995 lBF = `14.9627` Chr`14` : `49,355,219`	0.009	0.990	0.000
rs75258359 lBF = `8.02415` Chr`14` : `69,600,635`	0.009	0.991	0.000
rs2582532 lBF = `0.0391405` Chr`14` : `105,392,837`	0.009	0.991	0.000
rs117911949 lBF = `0.377711` Chr`14` : `72,016,789`	0.008	0.992	0.000
rs117693426 lBF = `13.2487` Chr`14` : `105,884,482`	0.008	0.992	0.000
rs1243507 lBF = `18.6876` Chr`14` : `95,314,433`	0.008	0.992	0.000
rs4496023 lBF = `22.4402` Chr`14` : `21,303,605`	0.008	0.992	0.000
rs7155279 lBF = `0.060255` Chr`14` : `92,485,881`	0.000	0.992	0.008
rs12433287 lBF = `12.511` Chr`14` : `75,697,380`	0.007	0.992	0.000
rs72668648 lBF = `13.4797` Chr`14` : `26,764,124`	0.007	0.993	0.000
rs117673410 lBF = `14.9552` Chr`14` : `50,519,643`	0.006	0.994	0.000
rs79694611 lBF = `14.1335` Chr`14` : `94,593,576`	0.006	0.994	0.000
rs1459148 lBF = `10.3063` Chr`14` : `98,840,443`	0.006	0.994	0.000
rs117608348 lBF = `10.9159` Chr`14` : `105,974,186`	0.005	0.994	0.000
rs945307 lBF = `13.1426` Chr`14` : `57,824,617`	0.005	0.994	0.000
rs6576086 lBF = `0.00570964` Chr`14` : `105,873,144`	0.000	0.994	0.005
rs117672662 lBF = `0.032178` Chr`14` : `69,425,467`	0.005	0.995	0.000
rs116002988 lBF = `0.00796389` Chr`14` : `99,457,437`	0.005	0.995	0.000
rs7158300 lBF = `-0.0592439` Chr`14` : `92,482,948`	0.000	0.995	0.005
rs74335365 lBF = `9.03859` Chr`14` : `60,693,242`	0.004	0.996	0.000
rs72662245 lBF = `8.76887` Chr`14` : `30,575,835`	0.004	0.996	0.000
rs8007689 lBF = `21.599` Chr`14` : `101,417,662`	0.004	0.996	0.000
rs116985836 lBF = `12.7976` Chr`14` : `41,256,353`	0.004	0.996	0.000
rs45484197 lBF = `11.2893` Chr`14` : `24,653,965`	0.004	0.996	0.000
rs75153334 lBF = `20.2913` Chr`14` : `22,426,873`	0.003	0.996	0.000
rs3811273 lBF = `-0.026019` Chr`14` : `22,715,158`	0.003	0.996	0.000
rs709400 lBF = `0.89509` Chr`14` : `104,149,475`	0.000	0.997	0.003
rs72708542 lBF = `5.17649` Chr`14` : `93,710,718`	0.003	0.997	0.000
rs118141139 lBF = `12.2839` Chr`14` : `96,787,278`	0.003	0.997	0.000
rs17609368 lBF = `6.30427` Chr`14` : `83,082,550`	0.003	0.997	0.000
rs185449237 lBF = `0.00377806` Chr`14` : `47,199,333`	0.003	0.997	0.000
rs12892019 lBF = `13.1568` Chr`14` : `25,759,476`	0.003	0.997	0.000
rs12586774 lBF = `3.15733` Chr`14` : `26,129,566`	0.003	0.997	0.000
rs117473458 lBF = `11.4108` Chr`14` : `38,261,632`	0.003	0.997	0.000
rs7141874 lBF = `-0.0353107` Chr`14` : `65,821,994`	0.003	0.997	0.000
rs76513344 lBF = `0.00295873` Chr`14` : `63,047,683`	0.002	0.997	0.000
rs17127407 lBF = `21.5936` Chr`14` : `23,647,729`	0.003	0.997	0.000
rs76176567 lBF = `14.1328` Chr`14` : `52,870,219`	0.002	0.997	0.000
rs6573333 lBF = `0.106706` Chr`14` : `61,308,337`	0.000	0.997	0.002
rs140436982 lBF = `4.22646` Chr`14` : `24,504,121`	0.002	0.998	0.000
rs12588287 lBF = `-0.0807838` Chr`14` : `92,536,959`	0.000	0.998	0.002
rs4904670 lBF = `0.00098541` Chr`14` : `90,770,210`	0.000	0.998	0.002
rs61976746 lBF = `16.9365` Chr`14` : `31,240,107`	0.002	0.998	0.000
rs6572843 lBF = `12.7917` Chr`14` : `52,864,237`	0.002	0.998	0.000
rs12883384 lBF = `0.152023` Chr`14` : `47,403,684`	0.000	0.998	0.001
rs10162376 lBF = `0.00098877` Chr`14` : `81,030,493`	0.001	0.999	0.000
rs8008716 lBF = `-0.0388744` Chr`14` : `27,125,765`	0.000	0.999	0.001
rs17880758 lBF = `7.86576` Chr`14` : `65,409,096`	0.001	0.999	0.000
rs115169421 lBF = `0.00090948` Chr`14` : `96,093,847`	0.001	0.999	0.000
rs191926782 lBF = `0.00081724` Chr`14` : `85,956,171`	0.001	0.999	0.000
rs1261741 lBF = `8.31313` Chr`14` : `83,222,515`	0.001	0.999	0.000
rs7155454 lBF = `-0.0431336` Chr`14` : `65,502,239`	0.000	0.999	0.001
rs8016620 lBF = `0.00254963` Chr`14` : `97,393,685`	0.001	0.999	0.000
rs7148590 lBF = `-0.0519013` Chr`14` : `65,473,196`	0.000	0.999	0.001
rs4466998 lBF = `-0.0155592` Chr`14` : `65,475,540`	0.000	0.999	0.001
rs78862578 lBF = `15.1649` Chr`14` : `72,663,062`	0.001	0.999	0.000
rs146750542 lBF = `0.00058545` Chr`14` : `32,500,171`	0.001	0.999	0.000
rs139134142 lBF = `0.00018876` Chr`14` : `92,069,489`	0.001	0.999	0.000
rs78222176 lBF = `16.052` Chr`14` : `100,115,473`	0.001	0.999	0.000
rs28489712 lBF = `0.00036831` Chr`14` : `55,483,786`	0.001	0.999	0.000
rs2143963 lBF = `0.00021584` Chr`14` : `54,723,923`	0.001	0.999	0.000
rs57602116 lBF = `0.0008998` Chr`14` : `95,283,220`	0.001	0.999	0.000
rs12185044 lBF = `5.81853` Chr`14` : `37,172,516`	0.001	0.999	0.000
rs181902743 lBF = `0` Chr`14` : `81,130,189`	0.001	0.999	0.001
rs4905994 lBF = `0` Chr`14` : `101,154,072`	0.001	0.999	0.001
rs79503702 lBF = `0` Chr`14` : `50,206,170`	0.001	0.999	0.001
rs140660435 lBF = `0` Chr`14` : `84,292,263`	0.001	0.999	0.001
rs190971703 lBF = `0` Chr`14` : `28,543,476`	0.001	0.999	0.001
rs2400749 lBF = `0` Chr`14` : `100,037,018`	0.001	0.999	0.001
rs1950626 lBF = `0` Chr`14` : `101,373,973`	0.001	0.999	0.001
rs17122693 lBF = `0` Chr`14` : `51,084,235`	0.001	0.999	0.001
rs149065551 lBF = `0` Chr`14` : `89,542,621`	0.001	0.999	0.001
rs6575793 lBF = `0` Chr`14` : `101,032,217`	0.001	0.999	0.001
rs1530947 lBF = `0` Chr`14` : `49,951,350`	0.001	0.999	0.001
rs1959536 lBF = `0` Chr`14` : `51,446,771`	0.001	0.999	0.001
rs2664299 lBF = `0` Chr`14` : `99,742,187`	0.001	0.999	0.001
rs941576 lBF = `0` Chr`14` : `101,306,045`	0.001	0.999	0.001
rs1265879 lBF = `0` Chr`14` : `50,877,983`	0.001	0.999	0.001
rs190480000 lBF = `0` Chr`14` : `82,031,121`	0.001	0.999	0.001
rs116335274 lBF = `0` Chr`14` : `28,614,388`	0.001	0.999	0.001
rs7157599 lBF = `0` Chr`14` : `100,625,902`	0.001	0.999	0.001
rs8008758 lBF = `0` Chr`14` : `101,690,045`	0.001	0.999	0.001
rs188669819 lBF = `0` Chr`14` : `47,351,022`	0.001	0.999	0.001
rs1953884 lBF = `0` Chr`14` : `51,326,166`	0.001	0.999	0.001
rs72698726 lBF = `0` Chr`14` : `101,188,618`	0.001	0.999	0.001
rs147168872 lBF = `0` Chr`14` : `50,639,995`	0.001	0.999	0.001
rs114791918 lBF = `0` Chr`14` : `28,598,027`	0.001	0.999	0.001
rs3742377 lBF = `0` Chr`14` : `100,166,228`	0.001	0.999	0.001
rs915364 lBF = `0` Chr`14` : `101,598,942`	0.001	0.999	0.001
rs76096589 lBF = `0` Chr`14` : `51,264,126`	0.001	0.999	0.001
rs192180133 lBF = `0` Chr`14` : `52,332,246`	0.001	0.999	0.001
rs192030704 lBF = `0` Chr`14` : `27,246,847`	0.001	0.999	0.001
rs138064340 lBF = `0` Chr`14` : `97,609,902`	0.001	0.999	0.001
rs7149242 lBF = `0` Chr`14` : `101,159,416`	0.001	0.999	0.001
rs10138297 lBF = `0` Chr`14` : `50,485,327`	0.001	0.999	0.001
rs138048027 lBF = `0` Chr`14` : `84,474,297`	0.001	0.999	0.001
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rs12882679 lBF = `-0.0020203` Chr`14` : `79,847,238`	0.000	1.000	0.000
rs751837 lBF = `-0.00319414` Chr`14` : `103,484,825`	0.000	1.000	0.000
rs724210 lBF = `-0.00634329` Chr`14` : `97,523,745`	0.000	1.000	0.000
rs718545 lBF = `-0.00884296` Chr`14` : `30,489,623`	0.000	1.000	0.000
rs12589060 lBF = `-0.0275918` Chr`14` : `89,437,416`	0.000	1.000	0.000
rs2029614 lBF = `-0.030753` Chr`14` : `99,547,267`	0.000	1.000	0.000
rs12436689 lBF = `-0.039969` Chr`14` : `85,654,019`	0.000	1.000	0.000
rs12435908 lBF = `-0.0513858` Chr`14` : `66,121,468`	0.000	1.000	0.000
rs17522122 lBF = `-0.0528604` Chr`14` : `33,302,882`	0.000	1.000	0.000
rs10144042 lBF = `-0.0653651` Chr`14` : `98,499,458`	0.000	1.000	0.000
rs8014204 lBF = `-0.068306` Chr`14` : `75,322,794`	0.000	1.000	0.000
rs4899685 lBF = `-0.0686256` Chr`14` : `78,421,058`	0.000	1.000	0.000
rs223116 lBF = `-0.0734359` Chr`14` : `23,977,010`	0.000	1.000	0.000
rs4322600 lBF = `-0.0801717` Chr`14` : `88,295,600`	0.000	1.000	0.000
rs2287375 lBF = `-0.0814736` Chr`14` : `77,684,842`	0.000	1.000	0.000
rs4467006 lBF = `-0.0830321` Chr`14` : `77,684,670`	0.000	1.000	0.000
rs17095029 lBF = `13.6715` Chr`14` : `72,140,969`	0.000	1.000	0.000
rs145561395 lBF = `10.9095` Chr`14` : `103,199,388`	0.000	1.000	0.000
rs116254114 lBF = `9.25391` Chr`14` : `21,228,586`	0.000	1.000	0.000
rs79574157 lBF = `7.67468` Chr`14` : `103,060,568`	0.000	1.000	0.000
rs72696787 lBF = `5.03372` Chr`14` : `80,173,873`	0.000	1.000	0.000
rs4384548 lBF = `2.26682` Chr`14` : `96,645,143`	0.000	1.000	0.000
rs74731421 lBF = `0.938135` Chr`14` : `38,210,286`	0.000	1.000	0.000
rs8009420 lBF = `0.685846` Chr`14` : `54,263,851`	0.000	1.000	0.000
rs148114321 lBF = `0.639906` Chr`14` : `36,213,442`	0.000	1.000	0.000
rs227425 lBF = `0.505785` Chr`14` : `70,456,699`	0.000	1.000	0.000
rs699363 lBF = `0.173027` Chr`14` : `72,692,493`	0.000	1.000	0.000
rs2076751 lBF = `0.0980318` Chr`14` : `36,989,419`	0.000	1.000	0.000
rs11625461 lBF = `0.040507` Chr`14` : `52,403,684`	0.000	1.000	0.000
rs10143078 lBF = `0.0301057` Chr`14` : `70,881,489`	0.000	1.000	0.000
rs35209784 lBF = `0.00609035` Chr`14` : `59,751,830`	0.000	1.000	0.000
rs12432260 lBF = `0.00383996` Chr`14` : `95,848,294`	0.000	1.000	0.000
rs17176043 lBF = `0.00204714` Chr`14` : `36,994,802`	0.000	1.000	0.000
rs2068012 lBF = `0.0015476` Chr`14` : `30,190,316`	0.000	1.000	0.000
rs17104630 lBF = `-0.0016712` Chr`14` : `37,000,049`	0.000	1.000	0.000
rs11622412 lBF = `-0.012084` Chr`14` : `38,683,261`	0.000	1.000	0.000
rs2693676 lBF = `-0.0146311` Chr`14` : `99,607,480`	0.000	1.000	0.000
rs2877649 lBF = `-0.0161482` Chr`14` : `24,954,002`	0.000	1.000	0.000
rs11621969 lBF = `-0.0177692` Chr`14` : `75,814,028`	0.000	1.000	0.000
rs7152554 lBF = `-0.0187462` Chr`14` : `84,597,385`	0.000	1.000	0.000
rs8006385 lBF = `-0.0317123` Chr`14` : `93,501,026`	0.000	1.000	0.000
rs35955841 lBF = `-0.0337909` Chr`14` : `65,319,361`	0.000	1.000	0.000
rs945270 lBF = `-0.0450119` Chr`14` : `56,200,473`	0.000	1.000	0.000
rs6574988 lBF = `-0.0473908` Chr`14` : `88,559,992`	0.000	1.000	0.000
rs12884468 lBF = `-0.0521086` Chr`14` : `35,852,486`	0.000	1.000	0.000
rs11624056 lBF = `-0.0677856` Chr`14` : `87,506,248`	0.000	1.000	0.000
rs2332700 lBF = `-0.0793436` Chr`14` : `72,417,326`	0.000	1.000	0.000
rs7150255 lBF = `-0.0833397` Chr`14` : `104,912,876`	0.000	1.000	0.000
rs11625034 lBF = `-0.0953113` Chr`14` : `54,349,976`	0.000	1.000	0.000
rs12589282 lBF = `-0.0979387` Chr`14` : `22,937,656`	0.000	1.000	0.000
rs2383378 lBF = `-0.109907` Chr`14` : `33,282,470`	0.000	1.000	0.000
rs7120 lBF = `-0.118587` Chr`14` : `96,010,589`	0.000	1.000	0.000
rs2369304 lBF = `-0.13489` Chr`14` : `96,206,070`	0.000	1.000	0.000
rs72684702 lBF = `11.0209` Chr`14` : `46,683,669`	0.000	1.000	0.000
rs12101261 lBF = `8.87041` Chr`14` : `81,451,229`	0.000	1.000	0.000
rs7146393 lBF = `7.92483` Chr`14` : `32,787,754`	0.000	1.000	0.000
rs17093520 lBF = `7.13877` Chr`14` : `74,346,295`	0.000	1.000	0.000
rs10498529 lBF = `6.78445` Chr`14` : `69,770,690`	0.000	1.000	0.000
rs17564083 lBF = `5.59903` Chr`14` : `29,967,193`	0.000	1.000	0.000
rs1612141 lBF = `2.4558` Chr`14` : `41,702,598`	0.000	1.000	0.000
rs12898084 lBF = `1.78487` Chr`14` : `56,253,404`	0.000	1.000	0.000
rs78807545 lBF = `1.66568` Chr`14` : `97,541,630`	0.000	1.000	0.000
rs11621135 lBF = `1.21794` Chr`14` : `71,659,609`	0.000	1.000	0.000
rs116909374 lBF = `0.909579` Chr`14` : `36,738,361`	0.000	1.000	0.000
rs7140285 lBF = `0.872006` Chr`14` : `88,462,988`	0.000	1.000	0.000
rs17108533 lBF = `0.245552` Chr`14` : `71,249,802`	0.000	1.000	0.000
rs2341534 lBF = `0.187922` Chr`14` : `55,784,737`	0.000	1.000	0.000
rs398652 lBF = `0.167566` Chr`14` : `56,525,569`	0.000	1.000	0.000
rs2337406 lBF = `0.149472` Chr`14` : `107,180,574`	0.000	1.000	0.000
rs148071215 lBF = `0.123842` Chr`14` : `83,272,653`	0.000	1.000	0.000
rs76745467 lBF = `0.113511` Chr`14` : `69,426,389`	0.000	1.000	0.000
rs17111396 lBF = `0.0897425` Chr`14` : `81,524,054`	0.000	1.000	0.000
rs17124581 lBF = `0.0823776` Chr`14` : `88,826,682`	0.000	1.000	0.000
rs57561811 lBF = `0.0781139` Chr`14` : `61,572,178`	0.000	1.000	0.000
rs2297067 lBF = `0.0694771` Chr`14` : `103,566,785`	0.000	1.000	0.000
rs1508945 lBF = `0.0681269` Chr`14` : `58,034,570`	0.000	1.000	0.000
rs2488856 lBF = `0.0435537` Chr`14` : `43,531,402`	0.000	1.000	0.000
rs12586478 lBF = `0.040885` Chr`14` : `86,768,365`	0.000	1.000	0.000
rs7159300 lBF = `0.0388465` Chr`14` : `72,883,874`	0.000	1.000	0.000
rs4902960 lBF = `0.0355215` Chr`14` : `72,432,149`	0.000	1.000	0.000
rs79110742 lBF = `0.0352416` Chr`14` : `83,347,928`	0.000	1.000	0.000
rs17118552 lBF = `0.0295303` Chr`14` : `47,874,557`	0.000	1.000	0.000
rs11847697 lBF = `0.027204` Chr`14` : `30,515,112`	0.000	1.000	0.000
rs12897644 lBF = `0.0206732` Chr`14` : `95,838,401`	0.000	1.000	0.000
rs2899832 lBF = `0.0137671` Chr`14` : `35,740,941`	0.000	1.000	0.000
rs7147087 lBF = `0.00910278` Chr`14` : `59,236,307`	0.000	1.000	0.000
rs117297873 lBF = `0.00850646` Chr`14` : `91,870,330`	0.000	1.000	0.000
rs36032616 lBF = `0.00464787` Chr`14` : `72,484,156`	0.000	1.000	0.000
rs4982029 lBF = `0.00185534` Chr`14` : `33,476,266`	0.000	1.000	0.000
rs79578553 lBF = `0.00155831` Chr`14` : `61,595,747`	0.000	1.000	0.000
rs8015959 lBF = `0.00116327` Chr`14` : `33,480,922`	0.000	1.000	0.000
rs4900022 lBF = `-0.00005395` Chr`14` : `90,615,513`	0.000	1.000	0.000
rs2144051 lBF = `-0.00137135` Chr`14` : `97,544,573`	0.000	1.000	0.000
rs2810114 lBF = `-0.00347665` Chr`14` : `71,395,604`	0.000	1.000	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0002

log Bayes Factor = 522.044

contains 22 variants

Cluster X0228

log Bayes Factor = 196.521

contains 11 variants

Cluster X0112

log Bayes Factor = 98.8923

contains 7 variants

Cluster X0199

log Bayes Factor = 350.038

contains 3 variants

Cluster X0335

log Bayes Factor = 12.3689

contains 1 variants

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

Cluster X0034

log Bayes Factor = 665.104

contains 16 variants

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

Cluster X0064

log Bayes Factor = 166.06

contains 10 variants

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

Cluster X0227

log Bayes Factor = 249.287

contains 11 variants

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

Cluster X0200

log Bayes Factor = 162.369

contains 2 variants

Cluster X0250

log Bayes Factor = 43.399

contains 4 variants

Cluster X0231

log Bayes Factor = 82.3185

contains 5 variants

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

Cluster X0204

log Bayes Factor = 169.796

contains 8 variants

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

Cluster X0294

log Bayes Factor = 25.2869

contains 2 variants

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

Cluster X0326

log Bayes Factor = 112.92

contains 5 variants

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

Cluster X0107

log Bayes Factor = 151.016

contains 1 variants

Cluster X0170

log Bayes Factor = 264.081

contains 11 variants

Cluster X0028

log Bayes Factor = 120.445

contains 7 variants

Cluster X0180

log Bayes Factor = 410.88

contains 15 variants

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

Cluster X0039

log Bayes Factor = 463.231

contains 17 variants

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

Cluster X0284

log Bayes Factor = 192.532

contains 9 variants

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

Cluster X0043

log Bayes Factor = 517.108

contains 20 variants

Cluster X0229

log Bayes Factor = 347.165

contains 13 variants

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

Cluster X0226

log Bayes Factor = 145.726

contains 8 variants

Cluster X0321

log Bayes Factor = 162.562

contains 1 variants

Cluster X0208

log Bayes Factor = 40.6733

contains 2 variants

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

Cluster X0307

log Bayes Factor = 826.86

contains 2 variants

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

Cluster X0104

log Bayes Factor = 122.44

contains 5 variants

Cluster X0297

log Bayes Factor = 63.8292

contains 4 variants

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

Cluster X0060

log Bayes Factor = 242.413

contains 5 variants

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

Cluster X0114

log Bayes Factor = 510.917

contains 25 variants

Cluster X0330

log Bayes Factor = 183.455

contains 2 variants

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

Cluster X0146

log Bayes Factor = 686.343

contains 22 variants

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

Cluster X0098

log Bayes Factor = 246.226

contains 8 variants

Cluster X0262

log Bayes Factor = 269.713

contains 9 variants

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

Cluster X0164

log Bayes Factor = 463.793

contains 16 variants

Cluster X0264

log Bayes Factor = 205.833

contains 10 variants

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

Cluster X0075

log Bayes Factor = 431.344

contains 16 variants

Cluster X0003

log Bayes Factor = 195.6

contains 8 variants

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

Cluster X0191

log Bayes Factor = 163.555

contains 8 variants

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

Cluster X0145

log Bayes Factor = 274.587

contains 11 variants

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.