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Diagnostic term associations

Hospitalization Episode Statistics (HES)

N95.8
Other specified menopausal and perimenopausal disorders
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs75033941 lBF = 14.4098   Chr7 : 15,616,587
0.685 0.315 0.000
rs60580184 lBF = 0.912577   Chr7 : 138,850,967
0.676 0.324 0.000
rs73079954 lBF = 16.4887   Chr7 : 24,746,536
0.673 0.327 0.000
rs80131195 lBF = 8.81707   Chr7 : 28,486,044
0.534 0.466 0.000
rs76721197 lBF = 12.9868   Chr7 : 106,727,200
0.469 0.531 0.000
rs11980091 lBF = 6.40349   Chr7 : 12,975,555
0.447 0.552 0.000
rs799979 lBF = 8.99497   Chr7 : 80,045,198
0.398 0.601 0.000
rs117346609 lBF = 16.6269   Chr7 : 96,852,491
0.373 0.627 0.000
rs116907527 lBF = 12.5204   Chr7 : 2,642,223
0.371 0.629 0.000
rs117420777 lBF = 14.9476   Chr7 : 63,529,988
0.363 0.637 0.000
rs10275663 lBF = 4.99211   Chr7 : 50,797,685
0.358 0.641 0.000
rs4149458 lBF = 0.348419   Chr7 : 65,709,777
0.342 0.657 0.000
rs6976769 lBF = 3.00178   Chr7 : 83,297,262
0.334 0.666 0.000
rs17837497 lBF = 0.843785   Chr7 : 139,702,593
0.334 0.666 0.000
rs75655068 lBF = 13.5772   Chr7 : 92,658,364
0.326 0.674 0.000
rs72602052 lBF = 12.3687   Chr7 : 28,500,531
0.308 0.692 0.000
rs113118439 lBF = 21.6211   Chr7 : 5,487,229
0.307 0.693 0.000
rs62471875 lBF = 16.6264   Chr7 : 154,778,171
0.295 0.704 0.000
rs138090874 lBF = 8.9374   Chr7 : 31,302,391
0.295 0.704 0.000
rs73313346 lBF = 11.9512   Chr7 : 18,723,232
0.290 0.710 0.000
rs3808343 lBF = 16.8732   Chr7 : 960,450
0.286 0.714 0.000
rs117420548 lBF = 14.7286   Chr7 : 104,775,976
0.283 0.717 0.000
rs72658822 lBF = 15.1905   Chr7 : 21,932,031
0.270 0.729 0.000
rs80261602 lBF = 3.9422   Chr7 : 122,271,315
0.258 0.742 0.000
rs75435968 lBF = 11.9878   Chr7 : 137,152,383
0.248 0.752 0.000
rs76672975 lBF = 17.6917   Chr7 : 66,210,447
0.247 0.753 0.000
rs10270308 lBF = 0.42551   Chr7 : 105,671,267
0.247 0.753 0.000
rs75404215 lBF = 14.5116   Chr7 : 15,472,901
0.241 0.759 0.000
rs113308315 lBF = 24.4022   Chr7 : 49,916,006
0.230 0.770 0.000
rs73180559 lBF = 24.7935   Chr7 : 82,760,550
0.227 0.773 0.000
rs138522855 lBF = 21.8188   Chr7 : 76,140,330
0.219 0.781 0.000
rs116910478 lBF = 15.3435   Chr7 : 89,932,032
0.203 0.797 0.000
rs6971778 lBF = 18.3704   Chr7 : 10,290,706
0.191 0.808 0.000
rs79009591 lBF = 19.33   Chr7 : 37,110,255
0.184 0.816 0.000
rs13227807 lBF = 14.7212   Chr7 : 68,454,912
0.183 0.816 0.000
rs17431838 lBF = 16.1776   Chr7 : 78,079,123
0.183 0.817 0.000
rs79066245 lBF = 14.7907   Chr7 : 10,283,364
0.175 0.824 0.000
rs12536985 lBF = 30.6778   Chr7 : 18,396,960
0.172 0.828 0.000
rs77502261 lBF = 18.4973   Chr7 : 124,095,846
0.151 0.849 0.000
rs74349534 lBF = 15.5514   Chr7 : 83,764,113
0.147 0.853 0.000
rs78900159 lBF = 3.80195   Chr7 : 76,968,378
0.130 0.870 0.000
rs117026326 lBF = 0.691935   Chr7 : 74,126,034
0.126 0.874 0.000
rs117792957 lBF = 22.6256   Chr7 : 71,899,700
0.125 0.874 0.000
rs2525776 lBF = 0.697836   Chr7 : 80,901,619
0.000 0.877 0.123
rs189806577 lBF = 0.168175   Chr7 : 34,977,270
0.109 0.890 0.000
rs117717824 lBF = 1.36934   Chr7 : 113,989,202
0.107 0.893 0.000
rs112161290 lBF = 22.7791   Chr7 : 37,129,797
0.102 0.897 0.000
rs113248159 lBF = 16.4871   Chr7 : 18,549,246
0.100 0.899 0.001
rs73143690 lBF = 18.8896   Chr7 : 98,201,780
0.091 0.909 0.000
rs75158997 lBF = 16.3135   Chr7 : 33,796,970
0.084 0.915 0.000
rs116853542 lBF = 17.1118   Chr7 : 18,656,230
0.084 0.915 0.000
rs80248311 lBF = 17.5452   Chr7 : 50,218,523
0.077 0.923 0.000
rs3025144 lBF = 17.2455   Chr7 : 24,273,159
0.072 0.928 0.000
rs75015237 lBF = 14.8383   Chr7 : 133,648,442
0.068 0.932 0.000
rs80311134 lBF = 15.2474   Chr7 : 156,876,169
0.065 0.934 0.000
rs74520339 lBF = 14.4457   Chr7 : 156,880,653
0.055 0.944 0.000
rs146131423 lBF = 14.8119   Chr7 : 75,896,741
0.053 0.947 0.000
rs116959808 lBF = 13.4797   Chr7 : 78,588,768
0.049 0.951 0.000
rs117487871 lBF = 18.8839   Chr7 : 50,073,888
0.046 0.954 0.000
rs112469508 lBF = 15.1969   Chr7 : 153,176,649
0.041 0.958 0.001
rs79818456 lBF = 12.4174   Chr7 : 33,808,171
0.041 0.959 0.000
rs4148805 lBF = 18.9159   Chr7 : 87,106,365
0.038 0.962 0.000
rs17684427 lBF = 1.53495   Chr7 : 122,482,977
0.038 0.962 0.000
rs142075585 lBF = 2.49144   Chr7 : 48,895,260
0.034 0.966 0.000
rs75480238 lBF = 16.88   Chr7 : 104,748,764
0.033 0.966 0.000
rs17437544 lBF = 16.9402   Chr7 : 27,231,189
0.033 0.967 0.000
rs150347869 lBF = 0.0262056   Chr7 : 46,897,555
0.032 0.968 0.000
rs10248351 lBF = 0.372047   Chr7 : 88,481,442
0.032 0.968 0.000
rs74522278 lBF = 14.9957   Chr7 : 5,156,883
0.030 0.970 0.000
rs188845491 lBF = 0.0404442   Chr7 : 99,286,639
0.029 0.971 0.000
rs6949729 lBF = 14.7152   Chr7 : 141,362,431
0.029 0.971 0.000
rs148490894 lBF = 0.101087   Chr7 : 99,531,755
0.028 0.972 0.000
rs11981919 lBF = 0.0370324   Chr7 : 152,669,840
0.027 0.973 0.000
rs17406405 lBF = 16.4915   Chr7 : 78,658,711
0.026 0.974 0.000
rs117631583 lBF = 15.1608   Chr7 : 78,667,335
0.025 0.975 0.000
rs191603973 lBF = 0.0394972   Chr7 : 155,101,686
0.024 0.975 0.000
rs117071818 lBF = 25.7501   Chr7 : 130,034,949
0.011 0.976 0.014
rs4148808 lBF = 18.9164   Chr7 : 87,105,795
0.023 0.977 0.000
rs4148807 lBF = 18.9699   Chr7 : 87,105,812
0.023 0.977 0.000
rs117489024 lBF = 12.3853   Chr7 : 3,906,324
0.023 0.977 0.000
rs80126971 lBF = 18.1379   Chr7 : 36,697,785
0.021 0.979 0.000
rs77282735 lBF = 12.7192   Chr7 : 45,090,949
0.020 0.980 0.000
rs10255329 lBF = 0.0269096   Chr7 : 13,440,222
0.019 0.980 0.000
rs6467710 lBF = 5.41598   Chr7 : 137,203,819
0.019 0.981 0.000
rs183498415 lBF = 0.0234329   Chr7 : 35,153,401
0.017 0.983 0.000
rs77261098 lBF = 14.059   Chr7 : 137,261,899
0.017 0.983 0.000
rs7458938 lBF = -0.072353   Chr7 : 125,460,648
0.000 0.983 0.017
rs45554032 lBF = 17.3797   Chr7 : 87,078,547
0.015 0.985 0.000
rs12538707 lBF = 19.6336   Chr7 : 87,124,268
0.015 0.985 0.000
rs2302387 lBF = 19.0709   Chr7 : 87,092,185
0.015 0.985 0.000
rs113161398 lBF = 14.3881   Chr7 : 50,859,432
0.014 0.986 0.000
rs2109505 lBF = 9.11073   Chr7 : 87,079,406
0.012 0.988 0.000
rs3842 lBF = 18.0375   Chr7 : 87,133,366
0.012 0.988 0.000
rs80264625 lBF = 18.0968   Chr7 : 124,140,827
0.012 0.988 0.000
rs73302615 lBF = 0.138596   Chr7 : 28,271,690
0.003 0.989 0.008
rs4148810 lBF = 10.9528   Chr7 : 87,102,251
0.011 0.989 0.000
rs236670 lBF = 2.17228   Chr7 : 75,059,331
0.010 0.990 0.000
rs73271426 lBF = 11.5943   Chr7 : 13,645,098
0.000 0.991 0.009
rs2286251 lBF = 14.6643   Chr7 : 107,702,877
0.009 0.991 0.000
rs117557765 lBF = 20.262   Chr7 : 6,974,872
0.009 0.991 0.000
rs118036280 lBF = 11.8215   Chr7 : 66,539,817
0.008 0.992 0.000
rs17064 lBF = 12.5491   Chr7 : 87,133,470
0.008 0.992 0.000
rs117620493 lBF = 19.1648   Chr7 : 67,995,633
0.008 0.992 0.000
rs117018013 lBF = 15.0209   Chr7 : 45,285,823
0.007 0.992 0.000
rs79698955 lBF = 0.0191953   Chr7 : 105,272,676
0.007 0.993 0.000
rs73178603 lBF = 12.117   Chr7 : 155,065,202
0.007 0.993 0.000
rs10279826 lBF = 3.2852   Chr7 : 51,698,193
0.006 0.994 0.000
rs740145 lBF = 0.0183006   Chr7 : 29,921,524
0.006 0.994 0.000
rs12666280 lBF = -0.0311724   Chr7 : 154,509,324
0.006 0.994 0.000
rs185158884 lBF = 1.32773   Chr7 : 21,014,993
0.001 0.994 0.005
rs73692310 lBF = 0.0082489   Chr7 : 46,006,655
0.005 0.994 0.000
rs73157036 lBF = -0.0202926   Chr7 : 136,431,840
0.006 0.994 0.000
rs10272474 lBF = 13.1578   Chr7 : 96,155,852
0.005 0.994 0.000
rs73157032 lBF = -0.0196123   Chr7 : 136,428,681
0.005 0.995 0.000
rs2366858 lBF = 0.0103449   Chr7 : 80,340,622
0.005 0.995 0.000
rs55704525 lBF = 0.0217842   Chr7 : 43,568,566
0.005 0.995 0.000
rs76014476 lBF = 18.1518   Chr7 : 105,107,249
0.005 0.995 0.000
rs7789850 lBF = 0.0146769   Chr7 : 141,300,611
0.005 0.995 0.000
rs2267739 lBF = -0.0225916   Chr7 : 31,136,897
0.005 0.995 0.000
rs73737676 lBF = 0.00537855   Chr7 : 155,810,501
0.005 0.995 0.000
rs6943090 lBF = 0.00551539   Chr7 : 72,746,648
0.004 0.995 0.000
rs1229542 lBF = -0.00648148   Chr7 : 97,422,926
0.000 0.995 0.005
rs151156903 lBF = -0.0225601   Chr7 : 136,366,355
0.005 0.995 0.000
rs4947642 lBF = -0.0255817   Chr7 : 51,865,608
0.005 0.995 0.000
rs73157010 lBF = -0.0169849   Chr7 : 136,396,861
0.004 0.995 0.000
rs117744271 lBF = 7.2886   Chr7 : 132,152,409
0.004 0.996 0.000
rs113070825 lBF = 18.5714   Chr7 : 17,430,916
0.004 0.996 0.000
rs2538958 lBF = 0.0169652   Chr7 : 147,615,640
0.000 0.996 0.004
rs73079182 lBF = 14.8264   Chr7 : 24,050,383
0.004 0.996 0.000
rs73366442 lBF = 12.0256   Chr7 : 73,989,491
0.003 0.996 0.001
rs12668095 lBF = 0.132447   Chr7 : 47,075,776
0.000 0.996 0.004
rs10254160 lBF = 3.78017   Chr7 : 111,967,290
0.004 0.996 0.000
rs114137957 lBF = 4.49603   Chr7 : 87,374,869
0.004 0.996 0.000
rs17168526 lBF = 0.00410054   Chr7 : 7,571,420
0.003 0.996 0.000
rs117375698 lBF = 0.004359   Chr7 : 67,715,708
0.003 0.996 0.000
rs79197728 lBF = 20.1944   Chr7 : 18,613,603
0.003 0.997 0.000
rs73093398 lBF = 10.983   Chr7 : 34,157,212
0.003 0.997 0.000
rs76027228 lBF = 5.06956   Chr7 : 73,422,593
0.003 0.997 0.000
rs3736638 lBF = 0.207425   Chr7 : 94,047,266
0.003 0.997 0.000
rs1179624 lBF = -0.00324872   Chr7 : 75,255,215
0.000 0.997 0.003
rs1561176 lBF = -0.0404703   Chr7 : 155,008,713
0.003 0.997 0.000
rs111576115 lBF = 15.9212   Chr7 : 50,712,649
0.003 0.997 0.000
rs148982377 lBF = 0.398419   Chr7 : 99,075,038
0.000 0.997 0.003
rs116841826 lBF = 21.5796   Chr7 : 150,543,427
0.003 0.997 0.000
rs56868568 lBF = 0.00984974   Chr7 : 19,164,880
0.002 0.997 0.000
rs62477606 lBF = 17.4246   Chr7 : 75,352,205
0.003 0.997 0.000
rs17867771 lBF = 17.3194   Chr7 : 126,766,816
0.003 0.997 0.000
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0.003 0.997 0.000
rs75016295 lBF = 11.3138   Chr7 : 153,908,935
0.002 0.997 0.000
rs2395909 lBF = 0.0828756   Chr7 : 107,292,663
0.000 0.997 0.003
rs73099645 lBF = 0.213252   Chr7 : 43,226,641
0.002 0.997 0.000
rs6966264 lBF = 5.82465   Chr7 : 87,543,037
0.002 0.997 0.000
rs10237735 lBF = 0.00194299   Chr7 : 32,376,748
0.002 0.997 0.000
rs10237103 lBF = 0.00559492   Chr7 : 79,662,227
0.002 0.998 0.000
rs2190422 lBF = 0.0324287   Chr7 : 103,066,776
0.002 0.998 0.000
rs139877884 lBF = 13.2633   Chr7 : 146,019,105
0.000 0.998 0.002
rs7807274 lBF = 0.00285468   Chr7 : 131,021,099
0.002 0.998 0.000
rs1371737 lBF = -0.0633101   Chr7 : 9,189,541
0.000 0.998 0.002
rs4379368 lBF = 0.0287007   Chr7 : 40,466,200
0.000 0.998 0.002
rs10227393 lBF = -0.0528696   Chr7 : 145,062,740
0.000 0.998 0.002
rs17807185 lBF = -0.028973   Chr7 : 77,308,295
0.000 0.998 0.002
rs2040992 lBF = 18.5499   Chr7 : 99,262,572
0.002 0.998 0.000
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0.002 0.998 0.000
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0.002 0.998 0.000
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0.002 0.998 0.000
rs1914395 lBF = -0.0241902   Chr7 : 71,839,408
0.000 0.998 0.002
rs245914 lBF = -0.0412105   Chr7 : 29,218,159
0.002 0.998 0.000
rs76780915 lBF = 23.1888   Chr7 : 145,876,658
0.002 0.998 0.000
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0.002 0.998 0.000
rs6978712 lBF = 0.173781   Chr7 : 127,147,763
0.002 0.998 0.000
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0.002 0.998 0.000
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0.000 0.998 0.002
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0.001 0.998 0.000
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0.002 0.998 0.000
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0.002 0.998 0.000
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0.001 0.998 0.000
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0.002 0.998 0.000
rs117132860 lBF = 4.72832   Chr7 : 17,134,708
0.001 0.998 0.000
rs6968865 lBF = -0.0368458   Chr7 : 17,287,269
0.000 0.998 0.001
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0.002 0.998 0.000
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0.001 0.998 0.000
rs314313 lBF = -0.104433   Chr7 : 100,423,365
0.002 0.998 0.000
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0.002 0.998 0.000
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0.001 0.998 0.000
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0.001 0.998 0.000
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0.002 0.998 0.000
rs117843550 lBF = 13.8383   Chr7 : 144,155,010
0.001 0.998 0.000
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0.001 0.998 0.000
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0.002 0.998 0.000
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0.001 0.998 0.000
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0.000 0.998 0.001
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0.001 0.999 0.000
rs115821935 lBF = 19.277   Chr7 : 90,738,831
0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
rs116859464 lBF = 15.7364   Chr7 : 156,086,970
0.001 0.999 0.001
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
rs1528149 lBF = 0.25884   Chr7 : 16,107,358
0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 1.000 0.000
rs62490898 lBF = 22.0013   Chr7 : 135,697,319
0.000 1.000 0.000
rs2074633 lBF = 21.593   Chr7 : 19,035,920
0.000 1.000 0.000
rs73090324 lBF = 13.0903   Chr7 : 29,683,765
0.000 1.000 0.000
rs56095547 lBF = 11.8156   Chr7 : 101,542,161
0.000 1.000 0.000
rs75672964 lBF = 11.0036   Chr7 : 131,321,010
0.000 1.000 0.000
rs7803069 lBF = 5.28469   Chr7 : 34,238,688
0.000 1.000 0.000
rs2470990 lBF = 3.04651   Chr7 : 47,386,790
0.000 1.000 0.000
rs849141 lBF = 1.31497   Chr7 : 28,185,091
0.000 1.000 0.000
rs60525454 lBF = 0.680418   Chr7 : 2,652,222
0.000 1.000 0.000
rs79209880 lBF = 0.0910906   Chr7 : 45,710,099
0.000 1.000 0.000
rs7801190 lBF = 0.0780627   Chr7 : 100,458,093
0.000 1.000 0.000
rs6963495 lBF = 0.041095   Chr7 : 105,166,853
0.000 1.000 0.000
rs73201076 lBF = 0.0297678   Chr7 : 110,775,399
0.000 1.000 0.000
rs17173608 lBF = 0.00678417   Chr7 : 150,036,664
0.000 1.000 0.000
rs10487524 lBF = 0.00610497   Chr7 : 144,841,531
0.000 1.000 0.000
rs12706411 lBF = -0.0206784   Chr7 : 122,065,219
0.000 1.000 0.000
rs1476587 lBF = -0.0245083   Chr7 : 86,696,714
0.000 1.000 0.000
rs11773845 lBF = -0.0374816   Chr7 : 116,191,301
0.000 1.000 0.000
rs700752 lBF = -0.0409218   Chr7 : 46,753,553
0.000 1.000 0.000
rs117699411 lBF = 14.2479   Chr7 : 18,378,068
0.000 1.000 0.000
rs111697632 lBF = 12.245   Chr7 : 101,274,811
0.000 1.000 0.000
rs6969131 lBF = 7.64503   Chr7 : 5,854,003
0.000 1.000 0.000
rs141480664 lBF = 1.7952   Chr7 : 4,509,589
0.000 1.000 0.000
rs11974528 lBF = 0.645825   Chr7 : 107,832,411
0.000 1.000 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.9565
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.8749
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.8331
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.8019
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.6683
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.6564
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.5939
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.5559
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.4430
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.4222
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.4208
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.4069
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.3777
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.3635
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.3525
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.3359
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.3117
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.2423
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.2402
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.2319
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.2262
Cluster X0306
log Bayes Factor = 24.0492
contains 2 variants
0.1843
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.1787
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.1696
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.1539
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.1371
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.1327
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.1323
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.1215
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.1140
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.1079
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.0712
Cluster X0244
log Bayes Factor = 122.647
contains 5 variants
0.0625
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.0578