TreeWAS – [Z89.5] Acquired absence of leg at or below knee

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs116877397 lBF = `30.7668` Chr`12` : `121,162,996`	0.685	0.315	0.000
rs117089640 lBF = `23.0292` Chr`12` : `125,048,557`	0.636	0.364	0.000
rs11108227 lBF = `16.4201` Chr`12` : `96,134,001`	0.620	0.379	0.000
rs12321507 lBF = `16.2879` Chr`12` : `96,134,818`	0.619	0.381	0.000
rs117091826 lBF = `24.5799` Chr`12` : `112,629,713`	0.612	0.388	0.000
rs144700679 lBF = `7.09223` Chr`12` : `115,468,959`	0.609	0.391	0.000
Affx-8411664 lBF = `18.4862` Chr`12` : `71,094,955`	0.609	0.391	0.000
rs11059555 lBF = `14.4188` Chr`12` : `128,646,039`	0.604	0.396	0.000
rs73045775 lBF = `23.3857` Chr`12` : `8,674,905`	0.602	0.398	0.000
rs117636037 lBF = `18.8537` Chr`12` : `38,519,375`	0.602	0.398	0.000
rs12423747 lBF = `15.1947` Chr`12` : `71,084,299`	0.599	0.401	0.000
rs79918060 lBF = `17.5524` Chr`12` : `58,407,669`	0.572	0.428	0.000
rs73141422 lBF = `22.399` Chr`12` : `83,882,469`	0.571	0.428	0.000
rs77649004 lBF = `14.247` Chr`12` : `96,135,916`	0.554	0.446	0.000
rs76001134 lBF = `19.3411` Chr`12` : `23,209,903`	0.549	0.451	0.000
rs215398 lBF = `19.4313` Chr`12` : `47,767,134`	0.549	0.451	0.000
rs61944384 lBF = `10.148` Chr`12` : `111,952,215`	0.000	0.455	0.545
rs61756485 lBF = `16.787` Chr`12` : `99,020,125`	0.544	0.456	0.000
rs112742247 lBF = `13.3959` Chr`12` : `85,030,619`	0.533	0.466	0.000
rs41279092 lBF = `7.635` Chr`12` : `112,924,706`	0.000	0.467	0.533
rs78221103 lBF = `16.6479` Chr`12` : `104,562,673`	0.528	0.472	0.000
rs117437287 lBF = `16.5299` Chr`12` : `23,389,839`	0.527	0.473	0.000
rs75489010 lBF = `27.7624` Chr`12` : `115,986,702`	0.524	0.476	0.000
rs34574480 lBF = `13.3586` Chr`12` : `115,307,567`	0.521	0.479	0.000
rs7298767 lBF = `17.6072` Chr`12` : `22,475,701`	0.514	0.486	0.000
rs12582852 lBF = `14.3759` Chr`12` : `3,315,933`	0.514	0.486	0.000
rs114453043 lBF = `22.0948` Chr`12` : `25,461,756`	0.514	0.486	0.000
rs76796201 lBF = `14.1948` Chr`12` : `23,091,755`	0.514	0.486	0.000
rs12813285 lBF = `22.3499` Chr`12` : `68,206,219`	0.514	0.486	0.000
rs35729753 lBF = `17.3029` Chr`12` : `66,672,379`	0.514	0.486	0.000
rs117139804 lBF = `18.4888` Chr`12` : `116,233,671`	0.513	0.487	0.000
rs75289085 lBF = `19.4964` Chr`12` : `18,147,653`	0.513	0.487	0.000
rs80160299 lBF = `15.0308` Chr`12` : `66,159,224`	0.509	0.491	0.000
rs118113273 lBF = `22.5923` Chr`12` : `128,300,100`	0.503	0.497	0.000
rs182057829 lBF = `2.49683` Chr`12` : `97,412,327`	0.476	0.524	0.000
rs3809128 lBF = `2.10909` Chr`12` : `56,709,919`	0.464	0.536	0.000
rs17102257 lBF = `14.6206` Chr`12` : `54,126,061`	0.460	0.540	0.000
rs117802803 lBF = `21.4181` Chr`12` : `22,796,804`	0.459	0.541	0.000
rs117929870 lBF = `16.9839` Chr`12` : `108,524,849`	0.439	0.561	0.000
rs1653608 lBF = `16.5227` Chr`12` : `121,706,733`	0.436	0.564	0.000
rs78437391 lBF = `22.4064` Chr`12` : `129,229,615`	0.430	0.570	0.000
rs2279695 lBF = `6.13321` Chr`12` : `117,154,262`	0.429	0.571	0.000
rs704080 lBF = `11.6648` Chr`12` : `89,749,223`	0.429	0.571	0.000
rs118009632 lBF = `0.732821` Chr`12` : `54,959,672`	0.000	0.592	0.408
rs2417373 lBF = `14.5305` Chr`12` : `14,744,468`	0.403	0.596	0.000
rs188610 lBF = `2.31323` Chr`12` : `313,839`	0.398	0.601	0.000
rs117759274 lBF = `14.7453` Chr`12` : `23,131,855`	0.390	0.609	0.000
rs192051543 lBF = `14.1247` Chr`12` : `22,657,770`	0.378	0.622	0.000
rs187986843 lBF = `15.061` Chr`12` : `69,080,770`	0.375	0.625	0.000
rs79015790 lBF = `14.8688` Chr`12` : `128,700,249`	0.352	0.647	0.000
rs117629949 lBF = `14.77` Chr`12` : `25,021,224`	0.337	0.663	0.000
rs6580622 lBF = `15.5075` Chr`12` : `47,936,778`	0.335	0.664	0.000
rs73164250 lBF = `17.0593` Chr`12` : `84,624,334`	0.279	0.720	0.000
rs73217910 lBF = `14.853` Chr`12` : `118,450,865`	0.275	0.725	0.000
rs35446494 lBF = `7.95755` Chr`12` : `119,533,218`	0.268	0.732	0.000
rs117458579 lBF = `15.4218` Chr`12` : `15,351,989`	0.264	0.736	0.000
rs187353341 lBF = `19.0434` Chr`12` : `121,557,376`	0.256	0.744	0.000
rs117557466 lBF = `12.1727` Chr`12` : `69,802,569`	0.246	0.754	0.000
rs117761474 lBF = `15.8826` Chr`12` : `113,029,356`	0.214	0.786	0.000
rs1528287 lBF = `13.6349` Chr`12` : `80,985,872`	0.204	0.796	0.000
rs10506821 lBF = `13.2804` Chr`12` : `80,496,923`	0.189	0.810	0.000
rs74910874 lBF = `2.61067` Chr`12` : `67,086,810`	0.177	0.822	0.000
rs117605016 lBF = `28.0976` Chr`12` : `129,614,385`	0.169	0.831	0.000
rs9332958 lBF = `5.25634` Chr`12` : `16,519,263`	0.163	0.836	0.000
rs78294386 lBF = `14.58` Chr`12` : `107,963,652`	0.158	0.841	0.000
rs1235153 lBF = `9.04692` Chr`12` : `48,110,325`	0.158	0.842	0.000
rs75311705 lBF = `0.456159` Chr`12` : `125,714,596`	0.137	0.863	0.000
rs76409154 lBF = `20.1612` Chr`12` : `85,692,134`	0.129	0.870	0.000
rs12425131 lBF = `16.2355` Chr`12` : `82,984,879`	0.125	0.875	0.000
rs77103806 lBF = `6.36663` Chr`12` : `23,021,423`	0.113	0.886	0.000
rs144288546 lBF = `0.146461` Chr`12` : `129,069,682`	0.111	0.889	0.000
rs116938548 lBF = `0.178688` Chr`12` : `4,808,251`	0.099	0.901	0.000
rs74911677 lBF = `20.5271` Chr`12` : `122,015,993`	0.094	0.905	0.000
rs17040357 lBF = `13.7026` Chr`12` : `108,665,316`	0.092	0.907	0.000
rs2608700 lBF = `16.0704` Chr`12` : `41,884,414`	0.091	0.909	0.000
rs181609621 lBF = `1.56948` Chr`12` : `32,810,759`	0.078	0.922	0.000
rs11609031 lBF = `16.3836` Chr`12` : `99,307,725`	0.071	0.928	0.000
rs76450399 lBF = `14.1937` Chr`12` : `9,143,781`	0.071	0.928	0.000
rs11608709 lBF = `15.4681` Chr`12` : `99,302,859`	0.071	0.929	0.000
rs3184504 lBF = `147.788` Chr`12` : `111,884,608`	0.071	0.929	0.000
rs77821460 lBF = `20.1742` Chr`12` : `20,274,936`	0.069	0.931	0.000
rs10774624 lBF = `108.174` Chr`12` : `111,833,788`	0.000	0.932	0.068
rs16906714 lBF = `0.0571485` Chr`12` : `30,860,557`	0.058	0.942	0.000
rs76242156 lBF = `19.5711` Chr`12` : `65,043,774`	0.058	0.942	0.000
rs56269309 lBF = `12.8645` Chr`12` : `127,453,025`	0.057	0.942	0.000
rs11175593 lBF = `2.45774` Chr`12` : `40,601,940`	0.057	0.943	0.000
rs7310615 lBF = `134.377` Chr`12` : `111,865,049`	0.000	0.954	0.046
rs10774625 lBF = `134.733` Chr`12` : `111,910,219`	0.044	0.956	0.000
rs79476482 lBF = `14.9329` Chr`12` : `76,084,550`	0.040	0.960	0.000
rs115720202 lBF = `18.7627` Chr`12` : `89,746,581`	0.040	0.960	0.000
rs4766578 lBF = `133.156` Chr`12` : `111,904,371`	0.000	0.960	0.039
rs117409850 lBF = `13.4266` Chr`12` : `106,057,582`	0.039	0.961	0.000
rs35587409 lBF = `12.2827` Chr`12` : `100,841,306`	0.036	0.963	0.000
rs11115322 lBF = `13.8059` Chr`12` : `83,019,188`	0.036	0.963	0.000
rs7137828 lBF = `136.212` Chr`12` : `111,932,800`	0.000	0.964	0.036
rs61943445 lBF = `13.7019` Chr`12` : `118,861,521`	0.034	0.966	0.000
rs79235855 lBF = `16.45` Chr`12` : `1,537,749`	0.033	0.967	0.000
rs11174454 lBF = `8.97302` Chr`12` : `62,781,002`	0.029	0.970	0.000
rs12582659 lBF = `4.82974` Chr`12` : `76,064,528`	0.028	0.972	0.000
rs183825572 lBF = `0.0255777` Chr`12` : `101,264,845`	0.027	0.972	0.000
rs79002142 lBF = `11.7979` Chr`12` : `85,143,591`	0.027	0.973	0.000
rs7307123 lBF = `21.9581` Chr`12` : `54,524,397`	0.026	0.974	0.000
rs597808 lBF = `138.181` Chr`12` : `111,973,358`	0.000	0.976	0.024
rs12422544 lBF = `1.68441` Chr`12` : `40,528,432`	0.018	0.981	0.000
rs78321382 lBF = `14.0322` Chr`12` : `17,070,922`	0.018	0.982	0.000
rs653178 lBF = `141.209` Chr`12` : `112,007,756`	0.015	0.985	0.000
rs188255132 lBF = `0.0230843` Chr`12` : `81,723,188`	0.015	0.985	0.000
rs4594074 lBF = `0.0140546` Chr`12` : `41,032,092`	0.014	0.986	0.000
rs75876943 lBF = `15.0045` Chr`12` : `86,555,845`	0.014	0.986	0.000
rs12371484 lBF = `19.7008` Chr`12` : `111,872,722`	0.013	0.986	0.000
rs12370770 lBF = `24.384` Chr`12` : `112,277,084`	0.012	0.987	0.000
rs117029533 lBF = `21.9889` Chr`12` : `66,632,067`	0.010	0.989	0.000
rs16932667 lBF = `-0.0776762` Chr`12` : `5,131,553`	0.000	0.989	0.011
rs1043763 lBF = `-0.0415101` Chr`12` : `122,630,909`	0.010	0.990	0.000
rs16914920 lBF = `12.1807` Chr`12` : `19,128,595`	0.010	0.990	0.000
rs17443266 lBF = `15.2354` Chr`12` : `19,169,453`	0.009	0.991	0.000
rs7307780 lBF = `0.176028` Chr`12` : `76,220,618`	0.009	0.991	0.000
rs11114027 lBF = `-0.0369385` Chr`12` : `79,775,248`	0.009	0.991	0.000
rs117492744 lBF = `13.2788` Chr`12` : `29,747,631`	0.009	0.991	0.000
rs7973748 lBF = `7.3862` Chr`12` : `20,164,705`	0.009	0.991	0.000
rs117863495 lBF = `14.7593` Chr`12` : `129,432,374`	0.008	0.992	0.000
rs118152513 lBF = `0.00652999` Chr`12` : `101,184,252`	0.000	0.992	0.008
rs117439611 lBF = `14.8831` Chr`12` : `520,944`	0.008	0.992	0.000
rs10777317 lBF = `-0.0607484` Chr`12` : `91,980,374`	0.000	0.992	0.008
rs12814941 lBF = `12.4883` Chr`12` : `106,408,172`	0.007	0.992	0.000
rs1920592 lBF = `0.100461` Chr`12` : `114,705,586`	0.007	0.993	0.000
rs149104283 lBF = `2.00778` Chr`12` : `21,083,862`	0.007	0.993	0.000
rs187293782 lBF = `0.0145963` Chr`12` : `76,157,356`	0.006	0.993	0.000
rs7310309 lBF = `-0.042297` Chr`12` : `79,811,429`	0.000	0.993	0.007
rs4238083 lBF = `14.8083` Chr`12` : `42,924,769`	0.007	0.993	0.000
rs12308914 lBF = `12.8877` Chr`12` : `104,633,842`	0.006	0.994	0.000
rs71454665 lBF = `8.54321` Chr`12` : `121,198,711`	0.006	0.994	0.000
rs11055612 lBF = `-0.0887438` Chr`12` : `13,923,328`	0.000	0.994	0.006
rs11247009 lBF = `-0.0668129` Chr`12` : `132,701,184`	0.000	0.994	0.006
rs673078 lBF = `-0.0673754` Chr`12` : `118,791,441`	0.000	0.994	0.006
rs2722223 lBF = `24.9818` Chr`12` : `90,233,876`	0.006	0.994	0.000
rs2261181 lBF = `5.79392` Chr`12` : `66,212,318`	0.006	0.994	0.000
rs1531343 lBF = `3.25594` Chr`12` : `66,174,894`	0.006	0.994	0.000
rs3752728 lBF = `6.24552` Chr`12` : `20,192,972`	0.006	0.994	0.000
rs117154046 lBF = `0.0198739` Chr`12` : `29,542,777`	0.005	0.994	0.000
rs73040424 lBF = `7.46879` Chr`12` : `5,665,454`	0.005	0.994	0.000
rs2733283 lBF = `17.1055` Chr`12` : `41,935,977`	0.005	0.995	0.000
rs55922880 lBF = `0.00435799` Chr`12` : `115,617,641`	0.005	0.995	0.000
rs183032784 lBF = `0.00474184` Chr`12` : `118,257,214`	0.004	0.995	0.000
rs17126180 lBF = `0.00493889` Chr`12` : `52,263,956`	0.000	0.996	0.004
rs182328274 lBF = `0.0032004` Chr`12` : `107,667,802`	0.004	0.996	0.000
rs118079879 lBF = `5.09035` Chr`12` : `41,713,306`	0.004	0.996	0.000
rs12367822 lBF = `-0.0581335` Chr`12` : `57,204,160`	0.004	0.996	0.000
rs2417820 lBF = `7.60635` Chr`12` : `20,190,474`	0.004	0.996	0.000
rs73114523 lBF = `14.6366` Chr`12` : `54,602,032`	0.004	0.996	0.000
rs59753639 lBF = `4.25806` Chr`12` : `25,140,690`	0.004	0.996	0.000
rs7137521 lBF = `0.00252492` Chr`12` : `126,734,269`	0.004	0.996	0.000
rs2657880 lBF = `0.0100386` Chr`12` : `56,863,770`	0.000	0.996	0.004
rs76775795 lBF = `13.6666` Chr`12` : `115,385,431`	0.004	0.996	0.000
rs76191003 lBF = `9.4885` Chr`12` : `47,182,531`	0.004	0.996	0.000
rs2638315 lBF = `-0.0199053` Chr`12` : `56,865,056`	0.000	0.996	0.004
rs4149639 lBF = `0.234732` Chr`12` : `6,442,001`	0.003	0.996	0.000
rs941184 lBF = `0.00357459` Chr`12` : `54,114,158`	0.003	0.996	0.000
rs11047510 lBF = `-0.0931089` Chr`12` : `8,989,916`	0.000	0.996	0.004
rs10860757 lBF = `-0.0409974` Chr`12` : `102,020,446`	0.004	0.996	0.000
rs3951439 lBF = `0.0044521` Chr`12` : `51,727,596`	0.000	0.996	0.003
rs12322695 lBF = `0.0399753` Chr`12` : `117,199,414`	0.003	0.997	0.000
rs2291738 lBF = `-0.104617` Chr`12` : `56,815,281`	0.000	0.997	0.003
rs885389 lBF = `0.0604974` Chr`12` : `131,621,762`	0.003	0.997	0.000
rs183160876 lBF = `0.00279977` Chr`12` : `82,463,439`	0.003	0.997	0.000
rs1040026 lBF = `0.00233431` Chr`12` : `71,210,678`	0.003	0.997	0.000
rs11170468 lBF = `0.160275` Chr`12` : `39,430,048`	0.000	0.997	0.003
rs3847687 lBF = `-0.0574797` Chr`12` : `131,525,053`	0.003	0.997	0.000
rs3217863 lBF = `9.55969` Chr`12` : `4,399,496`	0.003	0.997	0.000
rs522958 lBF = `-0.0794194` Chr`12` : `28,228,567`	0.003	0.997	0.000
rs2657879 lBF = `0.00817662` Chr`12` : `56,865,338`	0.000	0.997	0.003
rs1520223 lBF = `0.00239145` Chr`12` : `102,726,338`	0.002	0.997	0.000
rs1386003 lBF = `12.5875` Chr`12` : `13,213,682`	0.002	0.997	0.000
rs80132640 lBF = `11.0963` Chr`12` : `49,426,460`	0.002	0.997	0.000
rs34637584 lBF = `0.00195999` Chr`12` : `40,734,202`	0.002	0.997	0.000
rs11171846 lBF = `1.1123` Chr`12` : `56,828,056`	0.003	0.997	0.000
rs80002652 lBF = `18.6612` Chr`12` : `107,437,422`	0.002	0.997	0.000
rs10783624 lBF = `-0.0622892` Chr`12` : `39,522,907`	0.000	0.998	0.002
rs2965667 lBF = `-0.019105` Chr`12` : `17,444,733`	0.000	0.998	0.002
rs1531228 lBF = `-0.0326736` Chr`12` : `13,629,381`	0.002	0.998	0.000
rs11044722 lBF = `15.4222` Chr`12` : `19,781,710`	0.002	0.998	0.000
rs1373453 lBF = `0.0225389` Chr`12` : `70,054,910`	0.002	0.998	0.000
rs7309269 lBF = `13.6679` Chr`12` : `7,757,834`	0.002	0.998	0.000
rs11168936 lBF = `0.314265` Chr`12` : `49,645,240`	0.002	0.998	0.000
rs73200436 lBF = `2.81861` Chr`12` : `110,062,693`	0.002	0.998	0.000
rs7295246 lBF = `-0.0554447` Chr`12` : `43,967,677`	0.000	0.998	0.002
rs2731006 lBF = `-0.0616696` Chr`12` : `43,160,825`	0.000	0.998	0.002
rs3782464 lBF = `-0.0887077` Chr`12` : `114,804,580`	0.002	0.998	0.000
rs75593565 lBF = `13.6234` Chr`12` : `32,115,266`	0.002	0.998	0.000
rs117626015 lBF = `0.00164872` Chr`12` : `41,624,795`	0.002	0.998	0.000
rs10844154 lBF = `0.035124` Chr`12` : `32,380,501`	0.002	0.998	0.000
rs3764023 lBF = `6.6728` Chr`12` : `9,801,382`	0.000	0.998	0.002
rs111969502 lBF = `5.3967` Chr`12` : `59,848,381`	0.002	0.998	0.000
rs4149018 lBF = `0.00161931` Chr`12` : `21,291,561`	0.002	0.998	0.000
rs343092 lBF = `6.85645` Chr`12` : `66,250,940`	0.002	0.998	0.000
rs790006 lBF = `-0.0175315` Chr`12` : `64,606,439`	0.002	0.998	0.000
rs7978895 lBF = `-0.0953489` Chr`12` : `43,570,515`	0.000	0.998	0.002
rs11612508 lBF = `-0.0402079` Chr`12` : `12,657,513`	0.002	0.998	0.000
rs73313995 lBF = `22.0276` Chr`12` : `33,622,807`	0.002	0.998	0.000
rs143136847 lBF = `1.54314` Chr`12` : `82,748,339`	0.002	0.998	0.000
rs11057405 lBF = `-0.00458737` Chr`12` : `122,781,897`	0.000	0.998	0.002
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rs78549223 lBF = `13.151` Chr`12` : `71,168,008`	0.000	0.999	0.000
rs2285810 lBF = `5.79517` Chr`12` : `112,699,540`	0.001	0.999	0.000
rs7964120 lBF = `0.504282` Chr`12` : `74,087,808`	0.001	0.999	0.000
rs1458175 lBF = `0.083754` Chr`12` : `41,965,861`	0.001	0.999	0.000
rs2016266 lBF = `0.0818226` Chr`12` : `53,727,955`	0.001	0.999	0.000
rs12369635 lBF = `0.0404365` Chr`12` : `129,561,356`	0.000	0.999	0.001
rs2708377 lBF = `0.00974402` Chr`12` : `11,216,315`	0.000	0.999	0.001
rs1399439 lBF = `0.00947023` Chr`12` : `101,221,239`	0.001	0.999	0.000
rs7315621 lBF = `0.00150579` Chr`12` : `132,085,196`	0.001	0.999	0.000
rs1005956 lBF = `-0.030424` Chr`12` : `40,341,085`	0.000	0.999	0.001
rs703842 lBF = `-0.0489243` Chr`12` : `58,162,739`	0.000	0.999	0.001
rs11054731 lBF = `-0.0640627` Chr`12` : `12,376,465`	0.001	0.999	0.000
rs12424086 lBF = `-0.0712927` Chr`12` : `66,364,509`	0.000	0.999	0.001
rs11169552 lBF = `-0.0846184` Chr`12` : `51,155,663`	0.000	0.999	0.001
rs4768903 lBF = `0.0530954` Chr`12` : `51,045,449`	0.000	0.999	0.001
rs11177669 lBF = `-0.00206854` Chr`12` : `69,828,681`	0.000	0.999	0.000
rs7315438 lBF = `-0.0104322` Chr`12` : `115,891,403`	0.000	0.999	0.001
rs11174650 lBF = `-0.0389025` Chr`12` : `63,179,929`	0.001	0.999	0.000
rs17774123 lBF = `-0.0437176` Chr`12` : `54,241,279`	0.000	0.999	0.001
rs11045879 lBF = `-0.054771` Chr`12` : `21,382,619`	0.001	0.999	0.000
rs10506328 lBF = `-0.0563244` Chr`12` : `54,687,232`	0.000	0.999	0.001
rs4149080 lBF = `-0.0588165` Chr`12` : `21,377,559`	0.001	0.999	0.000
rs117624816 lBF = `14.1981` Chr`12` : `18,210,143`	0.000	0.999	0.000
rs1005902 lBF = `5.81327` Chr`12` : `112,667,675`	0.001	0.999	0.000
rs258415 lBF = `1.25111` Chr`12` : `28,017,522`	0.000	0.999	0.001
rs789560 lBF = `0.442685` Chr`12` : `70,331,827`	0.001	0.999	0.000
rs11172113 lBF = `0.0132012` Chr`12` : `57,527,283`	0.001	0.999	0.000
rs113681054 lBF = `-0.0236609` Chr`12` : `21,402,979`	0.001	0.999	0.000
rs4766986 lBF = `8.99695` Chr`12` : `113,076,475`	0.001	0.999	0.000
rs1131017 lBF = `8.6464` Chr`12` : `56,435,929`	0.001	0.999	0.000
rs117559199 lBF = `8.42044` Chr`12` : `75,424,551`	0.001	0.999	0.000
rs10876864 lBF = `8.27878` Chr`12` : `56,401,085`	0.000	0.999	0.001
rs1036429 lBF = `0.10408` Chr`12` : `96,271,428`	0.001	0.999	0.000
rs36104021 lBF = `-0.0330342` Chr`12` : `103,361,112`	0.000	0.999	0.001
rs1498694 lBF = `-0.0453526` Chr`12` : `103,257,876`	0.000	0.999	0.001
rs6489785 lBF = `-0.0856333` Chr`12` : `121,363,724`	0.000	0.999	0.001
rs7953528 lBF = `1.1414` Chr`12` : `28,017,159`	0.000	0.999	0.001
rs7294372 lBF = `0.932637` Chr`12` : `114,637,423`	0.000	0.999	0.000
rs1716403 lBF = `0.583299` Chr`12` : `124,519,846`	0.001	0.999	0.000
rs7485210 lBF = `0.126606` Chr`12` : `131,638,853`	0.001	0.999	0.000
rs10745841 lBF = `0.0859325` Chr`12` : `99,493,735`	0.000	0.999	0.001
rs77724872 lBF = `0.0190681` Chr`12` : `104,754,500`	0.001	0.999	0.000
rs1011728 lBF = `-0.0199219` Chr`12` : `85,695,613`	0.000	0.999	0.001
rs6487679 lBF = `-0.0441298` Chr`12` : `9,371,332`	0.001	0.999	0.000
rs11168854 lBF = `-0.118909` Chr`12` : `49,485,373`	0.001	0.999	0.000
rs650694 lBF = `14.526` Chr`12` : `52,906,586`	0.001	0.999	0.000
rs11175997 lBF = `12.485` Chr`12` : `66,401,444`	0.001	0.999	0.000
rs116962450 lBF = `7.81708` Chr`12` : `90,500,741`	0.000	0.999	0.000
rs11171739 lBF = `5.34477` Chr`12` : `56,470,625`	0.001	0.999	0.000
rs10744775 lBF = `4.3423` Chr`12` : `112,096,215`	0.001	0.999	0.000
rs12822662 lBF = `0.158725` Chr`12` : `38,863,670`	0.000	0.999	0.001
rs12580543 lBF = `0.102356` Chr`12` : `7,100,973`	0.000	0.999	0.001
rs150695384 lBF = `0.0114384` Chr`12` : `64,917,042`	0.001	0.999	0.000
rs11178918 lBF = `-0.0266819` Chr`12` : `72,125,285`	0.001	0.999	0.000
rs2058350 lBF = `-0.0673523` Chr`12` : `3,913,427`	0.001	0.999	0.000
rs11174267 lBF = `-0.113046` Chr`12` : `62,386,600`	0.001	0.999	0.000
rs7132908 lBF = `0.453103` Chr`12` : `50,263,148`	0.001	0.999	0.000
rs11059635 lBF = `0.31419` Chr`12` : `128,782,022`	0.001	0.999	0.000
rs10466868 lBF = `0.108617` Chr`12` : `131,939,920`	0.001	0.999	0.000
rs1265507 lBF = `0.0528145` Chr`12` : `114,868,138`	0.000	0.999	0.001
rs142494129 lBF = `0.0386533` Chr`12` : `95,161,353`	0.000	0.999	0.000
rs73200449 lBF = `0.0158231` Chr`12` : `110,078,967`	0.000	0.999	0.001
rs140785266 lBF = `0.00305033` Chr`12` : `86,195,923`	0.000	0.999	0.000
rs181697701 lBF = `0.00035088` Chr`12` : `107,611,050`	0.000	0.999	0.000
rs17108344 lBF = `-0.00155388` Chr`12` : `70,954,464`	0.000	0.999	0.000
rs7487873 lBF = `-0.0327614` Chr`12` : `64,727,456`	0.001	0.999	0.000
rs7358770 lBF = `-0.0870451` Chr`12` : `61,845,224`	0.000	0.999	0.001
rs12367572 lBF = `-0.0918376` Chr`12` : `45,290,466`	0.000	0.999	0.001
rs11057841 lBF = `14.6163` Chr`12` : `125,316,743`	0.000	0.999	0.000
rs11105468 lBF = `0.758357` Chr`12` : `90,328,833`	0.001	0.999	0.000
rs956451 lBF = `0.208532` Chr`12` : `2,684,702`	0.001	0.999	0.000
rs10849605 lBF = `0.0678492` Chr`12` : `1,064,438`	0.001	0.999	0.000
rs1385374 lBF = `0.0163696` Chr`12` : `129,300,694`	0.000	0.999	0.001
rs12282 lBF = `0.00394501` Chr`12` : `133,345,809`	0.000	0.999	0.000
rs12321565 lBF = `0.00259808` Chr`12` : `68,532,077`	0.001	0.999	0.000
rs499368 lBF = `-0.00108169` Chr`12` : `320,920`	0.000	0.999	0.000
rs1569019 lBF = `-0.0293583` Chr`12` : `131,576,191`	0.001	0.999	0.000
rs1847461 lBF = `-0.0443368` Chr`12` : `91,077,508`	0.001	0.999	0.000
rs1368578 lBF = `-0.0636707` Chr`12` : `76,476,956`	0.000	0.999	0.001
rs7301743 lBF = `-0.0821768` Chr`12` : `115,344,561`	0.001	0.999	0.000
rs2908835 lBF = `-0.0826364` Chr`12` : `11,648,418`	0.000	0.999	0.001
rs12824981 lBF = `-0.0966397` Chr`12` : `129,637,348`	0.000	0.999	0.001
rs10773568 lBF = `-0.12648` Chr`12` : `129,186,190`	0.001	0.999	0.000
rs3764022 lBF = `7.4239` Chr`12` : `9,833,524`	0.000	0.999	0.001
rs2134039 lBF = `6.11532` Chr`12` : `101,928,424`	0.000	0.999	0.001
rs10773087 lBF = `5.56414` Chr`12` : `124,878,404`	0.000	0.999	0.000
rs4474514 lBF = `0.605549` Chr`12` : `88,953,959`	0.001	0.999	0.000
rs2066808 lBF = `0.103548` Chr`12` : `56,737,973`	0.000	0.999	0.001
rs2066807 lBF = `0.0731955` Chr`12` : `56,740,682`	0.000	0.999	0.001
rs1443512 lBF = `0.0616224` Chr`12` : `54,342,684`	0.001	0.999	0.000
rs11044946 lBF = `0.0504246` Chr`12` : `20,081,335`	0.000	0.999	0.001
rs6538678 lBF = `0.0280281` Chr`12` : `96,261,568`	0.001	0.999	0.000
rs3891355 lBF = `0.0189252` Chr`12` : `106,950,695`	0.001	0.999	0.000
rs1678542 lBF = `0.0108876` Chr`12` : `57,968,715`	0.000	0.999	0.001
rs4765623 lBF = `0.00216448` Chr`12` : `125,320,850`	0.000	0.999	0.001
rs4764039 lBF = `-0.0106674` Chr`12` : `14,064,461`	0.001	0.999	0.000
rs1559997 lBF = `-0.016814` Chr`12` : `113,847,542`	0.001	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0333

log Bayes Factor = 38.671

contains 2 variants

0.3657

Cluster X0335

log Bayes Factor = 12.3689

contains 1 variants

0.2250

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

0.1448

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

0.9993

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

0.9977

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

0.9971

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

0.9941

Cluster X0015

log Bayes Factor = 356.23

contains 15 variants

0.9925

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

0.9910

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

0.9901

Cluster X0059

log Bayes Factor = 922.497

contains 26 variants

0.9901

Cluster X0164

log Bayes Factor = 463.793

contains 16 variants

0.9878

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

0.9871

Cluster X0222

log Bayes Factor = 431.582

contains 17 variants

0.9836

Cluster X0229

log Bayes Factor = 347.165

contains 13 variants

0.9830

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

0.9820

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

0.9796

Cluster X0046

log Bayes Factor = 387.972

contains 16 variants

0.9760

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

0.9760

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

0.9658

Cluster X0110

log Bayes Factor = 721.325

contains 13 variants

0.9645

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

0.9609

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

0.9556

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

0.9497

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

0.9484

Cluster X0326

log Bayes Factor = 112.92

contains 5 variants

0.9469

Cluster X0029

log Bayes Factor = 709.102

contains 23 variants

0.9468

Cluster X0079

log Bayes Factor = 413.803

contains 22 variants

0.9467

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

0.9451

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

0.9379

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

0.9377

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

0.9362

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

0.9351

Cluster X0148

log Bayes Factor = 315.237

contains 11 variants

0.9342

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

0.9316

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

0.9308

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

0.9178

Cluster X0146

log Bayes Factor = 686.343

contains 22 variants

0.9116

Cluster X0047

log Bayes Factor = 378.621

contains 14 variants

0.9093

Cluster X0043

log Bayes Factor = 517.108

contains 20 variants

0.9058

Cluster X0081

log Bayes Factor = 278.568

contains 10 variants

0.8988

Cluster X0055

log Bayes Factor = 274.911

contains 10 variants

0.8988

Cluster X0045

log Bayes Factor = 446.264

contains 16 variants

0.8958

Cluster X0082

log Bayes Factor = 496.905

contains 17 variants

0.8936

Cluster X0014

log Bayes Factor = 131.677

contains 6 variants

0.8909

Cluster X0224

log Bayes Factor = 278.692

contains 11 variants

0.8893

Cluster X0021

log Bayes Factor = 338.631

contains 13 variants

0.8880

Cluster X0268

log Bayes Factor = 213.591

contains 8 variants

0.8871

Cluster X0095

log Bayes Factor = 179.348

contains 8 variants

0.8831

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

0.8812

Cluster X0152

log Bayes Factor = 331.156

contains 10 variants

0.8806

Cluster X0189

log Bayes Factor = 149.681

contains 5 variants

0.8687

Cluster X0070

log Bayes Factor = 421.182

contains 15 variants

0.8675

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

0.8674

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

0.8645

Cluster X0057

log Bayes Factor = 439.35

contains 16 variants

0.8641

Cluster X0214

log Bayes Factor = 186.582

contains 8 variants

0.8633

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

0.8509

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

0.8452

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

0.8342

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

0.8306

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

0.8239

Cluster X0184

log Bayes Factor = 188.416

contains 8 variants

0.8235

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

0.8183

Cluster X0273

log Bayes Factor = 109.896

contains 6 variants

0.8141

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

0.8136

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

0.8116

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

0.8020

Cluster X0100

log Bayes Factor = 730.252

contains 26 variants

0.7989

Cluster X0257

log Bayes Factor = 281.184

contains 10 variants

0.7978

Cluster X0058

log Bayes Factor = 183.199

contains 8 variants

0.7977

Cluster X0165

log Bayes Factor = 303.727

contains 12 variants

0.7945

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

0.7878

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

0.7870

Cluster X0153

log Bayes Factor = 328.394

contains 11 variants

0.7839

Cluster X0159

log Bayes Factor = 152.327

contains 7 variants

0.7811

Cluster X0180

log Bayes Factor = 410.88

contains 15 variants

0.7764

Cluster X0001

log Bayes Factor = 167.541

contains 7 variants

0.7755

Cluster X0156

log Bayes Factor = 226.954

contains 9 variants

0.7747

Cluster X0054

log Bayes Factor = 197.338

contains 9 variants

0.7569

Cluster X0098

log Bayes Factor = 246.226

contains 8 variants

0.7546

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

0.7528

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

0.7483

Cluster X0068

log Bayes Factor = 127.774

contains 6 variants

0.7456

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

0.7389

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

0.7386

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

0.7324

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

0.7292

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

0.7239

Cluster X0279

log Bayes Factor = 52.8832

contains 2 variants

0.7228

Cluster X0226

log Bayes Factor = 145.726

contains 8 variants

0.7169

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

0.7148

Cluster X0274

log Bayes Factor = 454.783

contains 18 variants

0.7005

Cluster X0088

log Bayes Factor = 243.609

contains 9 variants

0.6990

Cluster X0063

log Bayes Factor = 107.557

contains 5 variants

0.6981

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

0.6964

Cluster X0039

log Bayes Factor = 463.231

contains 17 variants

0.6945

Cluster X0244

log Bayes Factor = 122.647

contains 5 variants

0.6820

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

0.6715

Cluster X0067

log Bayes Factor = 179.381

contains 8 variants

0.6666

Cluster X0050

log Bayes Factor = 397.79

contains 16 variants

0.6512

Cluster X0076

log Bayes Factor = 310.928

contains 15 variants

0.6234

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

0.6225

Cluster X0137

log Bayes Factor = 120.748

contains 4 variants

0.6205

Cluster X0132

log Bayes Factor = 267.393

contains 11 variants

0.6169

Cluster X0061

log Bayes Factor = 293.105

contains 15 variants

0.6144

Cluster X0166

log Bayes Factor = 230.746

contains 8 variants

0.5894

Cluster X0120

log Bayes Factor = 79.6695

contains 4 variants

0.5647

Cluster X0085

log Bayes Factor = 138.902

contains 6 variants

0.5632

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

0.5624

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

0.5569

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

0.5351

Cluster X0012

log Bayes Factor = 112.432

contains 5 variants

0.5304

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

0.5139

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

0.5097

Cluster X0145

log Bayes Factor = 274.587

contains 11 variants

0.4679

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

0.4619

Cluster X0237

log Bayes Factor = 123.902

contains 6 variants

0.4501

Cluster X0234

log Bayes Factor = 28.8983

contains 2 variants

0.4340

Cluster X0003

log Bayes Factor = 195.6

contains 8 variants

0.4328

Cluster X0013

log Bayes Factor = 548.265

contains 23 variants

0.4157

Cluster X0293

log Bayes Factor = 169.051

contains 7 variants

0.4143

Cluster X0264

log Bayes Factor = 205.833

contains 10 variants

0.3911

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

0.3804

Cluster X0138

log Bayes Factor = 43.7891

contains 4 variants

0.2669

Cluster X0210

log Bayes Factor = 426.159

contains 17 variants

0.2572

Cluster X0157

log Bayes Factor = 172.957

contains 8 variants

0.2538

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

0.2347

Cluster X0064

log Bayes Factor = 166.06

contains 10 variants

0.2146

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

0.2065

Cluster X0216

log Bayes Factor = 162.135

contains 6 variants

0.1880

Cluster X0140

log Bayes Factor = 164.536

contains 8 variants

0.1803

Cluster X0227

log Bayes Factor = 249.287

contains 11 variants

0.1654

Cluster X0154

log Bayes Factor = 282.084

contains 12 variants

0.1136

Cluster X0107

log Bayes Factor = 151.016

contains 1 variants

0.1070

Cluster X0074

log Bayes Factor = 353.38

contains 15 variants

0.1027

Cluster X0109

log Bayes Factor = 257.685

contains 11 variants

0.0971

Cluster X0141

log Bayes Factor = 742.063

contains 30 variants

0.0889

Cluster X0324

log Bayes Factor = 32.1341

contains 1 variants

0.0607

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

0.0584

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Diagnostic term associations

Hospitalization Episode Statistics (`HES`)

(posterior probability > 0.05)

(posterior probability > 0.05)

Diagnostic term associations

Hospitalization Episode Statistics (HES)

(posterior probability > 0.05)

(posterior probability > 0.05)

Hospitalization Episode Statistics (`HES`)