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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

M88
Paget's disease of bone [osteitis deformans]
Parent term
M86-M90 Other osteopathies
Nested terms
M88.0 Paget's disease of skull
M88.8 Paget's disease of other bones
M88.9 Paget's disease of bone, unspecified
What are diagnostic terms?
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs17831506 lBF = 7.89004   Chr16 : 49,016,296
0.760 0.240 0.000
rs117604355 lBF = 8.1344   Chr16 : 82,276,031
0.738 0.261 0.000
rs72781450 lBF = 8.96513   Chr16 : 13,988,334
0.726 0.274 0.000
rs12443701 lBF = 16.477   Chr16 : 77,302,444
0.710 0.290 0.000
rs117073822 lBF = 14.7798   Chr16 : 21,337,217
0.694 0.306 0.000
rs7185320 lBF = 8.98742   Chr16 : 57,101,373
0.684 0.316 0.000
rs7190199 lBF = 9.04801   Chr16 : 57,101,340
0.680 0.319 0.000
rs4783278 lBF = 8.34675   Chr16 : 82,829,767
0.646 0.354 0.000
rs79523270 lBF = 9.90193   Chr16 : 88,443,748
0.640 0.360 0.000
rs117167356 lBF = 12.9266   Chr16 : 50,029,488
0.637 0.363 0.000
rs138450362 lBF = 1.99354   Chr16 : 22,950,613
0.636 0.364 0.000
rs76861960 lBF = 13.3651   Chr16 : 77,599,439
0.617 0.383 0.000
rs139338093 lBF = 17.683   Chr16 : 84,778,766
0.616 0.384 0.000
rs112572951 lBF = 28.6867   Chr16 : 7,462,090
0.616 0.384 0.000
rs17713676 lBF = 1.1768   Chr16 : 79,073,421
0.609 0.391 0.000
rs4389167 lBF = 5.82795   Chr16 : 74,592,132
0.609 0.391 0.000
rs117458000 lBF = 12.1666   Chr16 : 79,776,544
0.601 0.399 0.000
rs6420398 lBF = 18.8598   Chr16 : 76,991,593
0.596 0.404 0.000
rs61744392 lBF = 12.8838   Chr16 : 67,037,035
0.592 0.408 0.000
rs138642423 lBF = 3.85062   Chr16 : 84,310,399
0.588 0.412 0.000
rs8044050 lBF = 16.7322   Chr16 : 74,922,857
0.587 0.413 0.000
rs118155048 lBF = 12.4591   Chr16 : 55,189,457
0.582 0.417 0.000
rs8045590 lBF = 6.79603   Chr16 : 6,114,071
0.581 0.419 0.000
rs1303874 lBF = 20.4674   Chr16 : 76,434,865
0.578 0.422 0.000
rs41321249 lBF = 14.692   Chr16 : 31,341,424
0.576 0.424 0.000
rs75193761 lBF = 11.2566   Chr16 : 67,233,243
0.570 0.430 0.000
rs72799290 lBF = 21.6918   Chr16 : 84,121,289
0.569 0.430 0.000
rs78873708 lBF = 28.1642   Chr16 : 7,408,842
0.569 0.431 0.000
rs9935937 lBF = 0.946034   Chr16 : 74,986,485
0.568 0.431 0.000
rs77682898 lBF = 24.1144   Chr16 : 26,717,490
0.566 0.433 0.000
rs118022586 lBF = 15.2786   Chr16 : 89,001,840
0.566 0.434 0.000
rs117530360 lBF = 16.4491   Chr16 : 1,952,972
0.566 0.434 0.000
rs112247854 lBF = 14.4224   Chr16 : 7,291,344
0.565 0.435 0.000
rs35053137 lBF = 12.277   Chr16 : 81,590,859
0.565 0.435 0.000
rs79656987 lBF = 12.8741   Chr16 : 67,357,900
0.559 0.441 0.000
rs61733768 lBF = 11.6573   Chr16 : 67,213,950
0.558 0.442 0.000
rs11150606 lBF = 14.614   Chr16 : 31,099,011
0.557 0.443 0.000
rs72805156 lBF = 15.3888   Chr16 : 85,887,242
0.557 0.443 0.000
rs75005694 lBF = 15.5513   Chr16 : 28,320,382
0.556 0.443 0.000
rs74635150 lBF = 14.3707   Chr16 : 54,673,627
0.556 0.444 0.000
rs80167425 lBF = 13.1983   Chr16 : 55,715,542
0.550 0.450 0.000
rs11645236 lBF = 19.5773   Chr16 : 54,713,198
0.546 0.454 0.000
rs11641700 lBF = 7.55882   Chr16 : 57,780,381
0.542 0.457 0.000
rs4782160 lBF = 13.3659   Chr16 : 14,650,645
0.540 0.460 0.000
rs9936351 lBF = 16.9967   Chr16 : 6,141,379
0.537 0.462 0.000
rs79272333 lBF = 13.5184   Chr16 : 65,995,651
0.536 0.464 0.000
rs117535546 lBF = 19.5942   Chr16 : 65,916,225
0.536 0.464 0.000
rs34641959 lBF = 19.1716   Chr16 : 85,568,804
0.535 0.465 0.000
rs2288017 lBF = 12.487   Chr16 : 84,793,749
0.532 0.468 0.000
rs189013090 lBF = 15.7644   Chr16 : 22,826,046
0.531 0.469 0.000
rs9652781 lBF = 17.8088   Chr16 : 195,391
0.531 0.469 0.000
rs76114334 lBF = 19.0254   Chr16 : 83,093,295
0.530 0.470 0.000
rs76246633 lBF = 27.2748   Chr16 : 74,924,716
0.529 0.471 0.000
rs1641895 lBF = 14.1003   Chr16 : 12,641,115
0.529 0.471 0.000
rs7187223 lBF = 13.0009   Chr16 : 82,457,733
0.527 0.473 0.000
rs118175001 lBF = 26.7437   Chr16 : 72,724,630
0.527 0.473 0.000
rs75116029 lBF = 15.377   Chr16 : 13,489,294
0.526 0.474 0.000
rs113797007 lBF = 25.0423   Chr16 : 12,649,840
0.525 0.475 0.000
rs75638798 lBF = 1.42101   Chr16 : 6,504,024
0.522 0.478 0.000
rs193031333 lBF = 7.91451   Chr16 : 79,189,810
0.521 0.479 0.000
rs6500745 lBF = 6.23499   Chr16 : 6,113,694
0.520 0.479 0.000
rs112817022 lBF = 21.0666   Chr16 : 22,274,136
0.517 0.483 0.000
rs117453948 lBF = 17.5477   Chr16 : 77,965,459
0.517 0.483 0.000
rs56276220 lBF = 14.6281   Chr16 : 28,330,317
0.515 0.485 0.000
rs9924009 lBF = 6.18168   Chr16 : 11,782,049
0.514 0.486 0.000
rs76309893 lBF = 21.1949   Chr16 : 13,228,713
0.514 0.486 0.000
rs710079 lBF = 14.6065   Chr16 : 129,223
0.514 0.486 0.000
rs181167431 lBF = 11.0835   Chr16 : 74,079,026
0.514 0.486 0.000
rs117664943 lBF = 16.2944   Chr16 : 52,408,480
0.513 0.487 0.000
rs118183808 lBF = 15.0414   Chr16 : 71,438,393
0.512 0.487 0.000
rs75495766 lBF = 31.5977   Chr16 : 72,693,940
0.512 0.488 0.000
rs12149070 lBF = 10.9184   Chr16 : 70,913,984
0.511 0.488 0.000
rs117097463 lBF = 17.5524   Chr16 : 48,610,292
0.511 0.489 0.000
rs117312671 lBF = 24.8436   Chr16 : 67,936,863
0.511 0.489 0.000
rs117582629 lBF = 8.51744   Chr16 : 12,456,402
0.510 0.490 0.000
rs117285773 lBF = 14.3986   Chr16 : 5,628,412
0.508 0.492 0.000
rs113501257 lBF = 17.3074   Chr16 : 21,722,406
0.508 0.492 0.000
rs72791114 lBF = 8.04324   Chr16 : 72,205,671
0.507 0.492 0.000
rs4494548 lBF = 2.26913   Chr16 : 20,371,588
0.504 0.496 0.000
rs9926335 lBF = 6.67192   Chr16 : 56,583,726
0.502 0.498 0.000
rs42471 lBF = 8.92286   Chr16 : 75,480,608
0.502 0.498 0.000
rs76475900 lBF = 15.2634   Chr16 : 59,672,738
0.501 0.499 0.000
rs74347133 lBF = 17.4128   Chr16 : 13,216,365
0.500 0.500 0.000
rs113920704 lBF = 31.1936   Chr16 : 7,472,397
0.499 0.501 0.000
rs7192981 lBF = 9.18729   Chr16 : 75,339,131
0.499 0.501 0.000
rs79395151 lBF = 12.3279   Chr16 : 22,272,027
0.497 0.503 0.000
rs117019691 lBF = 21.5576   Chr16 : 57,505,625
0.492 0.508 0.000
rs8062326 lBF = 10.0922   Chr16 : 19,156,016
0.489 0.511 0.000
rs17774983 lBF = 12.6669   Chr16 : 89,493,234
0.484 0.516 0.000
rs75885813 lBF = 12.9219   Chr16 : 7,141,263
0.482 0.518 0.000
rs116183707 lBF = 14.8739   Chr16 : 7,142,287
0.480 0.520 0.000
rs140556148 lBF = 6.77472   Chr16 : 71,346,949
0.478 0.522 0.000
rs118099348 lBF = 2.12723   Chr16 : 19,435,029
0.477 0.523 0.000
rs61502801 lBF = 11.9032   Chr16 : 12,248,879
0.477 0.523 0.000
rs117153386 lBF = 8.12893   Chr16 : 69,634,727
0.474 0.526 0.000
rs1982955 lBF = 7.12195   Chr16 : 76,969,598
0.473 0.527 0.000
rs76681713 lBF = 24.4335   Chr16 : 72,333,346
0.473 0.527 0.000
rs2301601 lBF = 7.06119   Chr16 : 23,366,528
0.469 0.530 0.000
rs77172747 lBF = 11.7522   Chr16 : 67,605,125
0.469 0.531 0.000
rs37603 lBF = 9.49661   Chr16 : 75,505,567
0.468 0.531 0.000
rs117602470 lBF = 13.2546   Chr16 : 32,585,912
0.468 0.532 0.000
rs16970670 lBF = 6.69072   Chr16 : 72,225,187
0.467 0.533 0.000
rs111696352 lBF = 17.5381   Chr16 : 81,790,491
0.458 0.542 0.000
rs12925413 lBF = 8.50475   Chr16 : 7,241,628
0.453 0.547 0.000
rs12051272 lBF = 1.61799   Chr16 : 82,663,288
0.453 0.547 0.000
rs12691052 lBF = 4.46234   Chr16 : 57,007,512
0.451 0.549 0.000
rs11864146 lBF = 7.6214   Chr16 : 84,046,715
0.449 0.551 0.000
rs34735233 lBF = 8.29735   Chr16 : 3,993,318
0.448 0.552 0.000
rs11644694 lBF = 7.27682   Chr16 : 58,557,342
0.446 0.553 0.000
rs74934799 lBF = 13.1374   Chr16 : 75,468,490
0.444 0.556 0.000
rs79274317 lBF = 9.38319   Chr16 : 7,354,883
0.439 0.561 0.000
rs55723035 lBF = 12.5757   Chr16 : 75,490,145
0.438 0.561 0.000
rs186112291 lBF = 3.93539   Chr16 : 31,213,181
0.429 0.571 0.000
rs145996888 lBF = 5.16769   Chr16 : 31,525,628
0.429 0.571 0.000
rs117096873 lBF = 11.0059   Chr16 : 11,386,960
0.424 0.576 0.000
rs74013184 lBF = 7.38165   Chr16 : 24,363,769
0.421 0.579 0.000
rs75397367 lBF = 8.07931   Chr16 : 84,041,217
0.420 0.580 0.000
rs75896014 lBF = 10.709   Chr16 : 24,531,387
0.393 0.607 0.000
rs62043710 lBF = 11.5928   Chr16 : 79,979,067
0.392 0.608 0.000
rs138436123 lBF = 5.39195   Chr16 : 2,978,068
0.382 0.618 0.000
rs58563355 lBF = 20.9719   Chr16 : 1,199,938
0.379 0.621 0.000
rs3751845 lBF = 2.9765   Chr16 : 3,778,337
0.377 0.623 0.000
rs201918052 lBF = 21.0846   Chr16 : 30,772,988
0.376 0.623 0.000
rs34952337 lBF = 5.6582   Chr16 : 66,470,822
0.376 0.624 0.000
rs75522355 lBF = 12.1753   Chr16 : 6,640,457
0.356 0.643 0.000
rs282232 lBF = 13.7114   Chr16 : 56,597,350
0.355 0.644 0.000
rs149808359 lBF = 0.884594   Chr16 : 31,384,127
0.355 0.645 0.000
rs149740259 lBF = 3.65077   Chr16 : 83,783,828
0.349 0.651 0.000
rs16967753 lBF = 2.08166   Chr16 : 64,635,403
0.347 0.653 0.000
rs61744716 lBF = 12.8365   Chr16 : 30,569,349
0.342 0.658 0.000
rs8060581 lBF = 0.494239   Chr16 : 80,192,605
0.335 0.664 0.000
rs666636 lBF = 12.3872   Chr16 : 56,601,720
0.313 0.687 0.000
rs17674099 lBF = 12.945   Chr16 : 81,506,593
0.302 0.698 0.000
rs5743292 lBF = 9.66373   Chr16 : 50,759,731
0.295 0.705 0.000
rs2229288 lBF = 0.309738   Chr16 : 72,828,304
0.257 0.743 0.000
rs11642961 lBF = 5.1645   Chr16 : 7,139,435
0.252 0.748 0.000
rs75781922 lBF = 11.3472   Chr16 : 88,149,539
0.251 0.749 0.000
rs71384569 lBF = 6.74754   Chr16 : 50,593,084
0.248 0.751 0.000
rs139875745 lBF = 0.419107   Chr16 : 31,396,892
0.217 0.783 0.000
rs35420030 lBF = 5.6979   Chr16 : 53,935,407
0.205 0.795 0.000
rs77859761 lBF = 18.8632   Chr16 : 81,993,215
0.193 0.807 0.000
rs75957893 lBF = 8.17006   Chr16 : 75,381,816
0.178 0.821 0.000
rs58144239 lBF = 0.2532   Chr16 : 12,759,509
0.170 0.830 0.000
rs6497718 lBF = 0.200184   Chr16 : 24,091,838
0.146 0.854 0.000
rs7192208 lBF = 0.0432767   Chr16 : 77,329,641
0.128 0.872 0.000
rs58296637 lBF = 0.139588   Chr16 : 76,463,936
0.125 0.875 0.000
rs1121980 lBF = 51.6781   Chr16 : 53,809,247
0.123 0.877 0.000
rs77061563 lBF = 6.51949   Chr16 : 11,452,542
0.119 0.880 0.000
rs7205511 lBF = 0.148372   Chr16 : 24,094,703
0.113 0.887 0.000
rs7190458 lBF = 4.70261   Chr16 : 75,263,661
0.110 0.890 0.000
rs111756027 lBF = 0.0820002   Chr16 : 77,318,111
0.110 0.890 0.000
rs12929627 lBF = 0.124398   Chr16 : 24,094,977
0.104 0.896 0.000
rs8050940 lBF = 0.0737519   Chr16 : 62,100,211
0.097 0.903 0.000
rs9940128 lBF = 50.6204   Chr16 : 53,800,754
0.094 0.906 0.000
rs190542424 lBF = 2.80667   Chr16 : 34,377,824
0.088 0.912 0.000
rs2066847 lBF = 5.18245   Chr16 : 50,763,778
0.087 0.913 0.000
rs189794920 lBF = 0.0931077   Chr16 : 2,658,385
0.086 0.914 0.000
rs76653830 lBF = 9.27013   Chr16 : 84,836,091
0.085 0.915 0.000
rs35526040 lBF = 0.0915799   Chr16 : 24,093,337
0.083 0.917 0.000
rs117268490 lBF = 14.8328   Chr16 : 81,830,515
0.080 0.920 0.000
rs34289708 lBF = 0.0906836   Chr16 : 24,095,374
0.080 0.920 0.000
rs11864332 lBF = 0.085269   Chr16 : 12,977,062
0.075 0.924 0.000
rs62057608 lBF = 5.08013   Chr16 : 34,682,193
0.068 0.932 0.000
rs141218390 lBF = 8.40175   Chr16 : 88,501,386
0.060 0.939 0.000
rs7199390 lBF = 0.116764   Chr16 : 11,313,051
0.050 0.950 0.000
rs11867071 lBF = 14.7556   Chr16 : 68,760,442
0.046 0.951 0.003
rs117331002 lBF = 5.16067   Chr16 : 34,374,522
0.048 0.952 0.000
rs79214645 lBF = 5.90548   Chr16 : 34,380,004
0.044 0.956 0.000
rs62036855 lBF = 15.9862   Chr16 : 26,232,045
0.043 0.956 0.000
rs770764 lBF = 17.7903   Chr16 : 60,303,723
0.040 0.959 0.000
rs73598796 lBF = 12.129   Chr16 : 82,025,794
0.039 0.960 0.000
rs79358781 lBF = 0.0343247   Chr16 : 80,298,550
0.037 0.962 0.000
rs9941349 lBF = 46.4333   Chr16 : 53,825,488
0.036 0.964 0.000
rs12921419 lBF = 0.0356997   Chr16 : 24,089,771
0.034 0.966 0.000
rs1558902 lBF = 52.4011   Chr16 : 53,803,574
0.030 0.970 0.000
rs1421085 lBF = 51.7214   Chr16 : 53,800,954
0.026 0.974 0.000
rs117254288 lBF = 12.3689   Chr16 : 32,379,046
0.000 0.976 0.024
rs2859631 lBF = 0.0285956   Chr16 : 78,631,794
0.019 0.981 0.000
rs6624 lBF = 6.43307   Chr16 : 75,327,916
0.016 0.984 0.000
rs17232120 lBF = 9.61677   Chr16 : 89,880,844
0.016 0.984 0.000
rs4150167 lBF = 0.122519   Chr16 : 84,213,684
0.015 0.985 0.000
rs9934540 lBF = 0.137432   Chr16 : 77,876,763
0.015 0.985 0.000
rs80213544 lBF = 10.5045   Chr16 : 75,116,252
0.014 0.986 0.000
rs11075747 lBF = 5.5427   Chr16 : 69,940,361
0.012 0.988 0.000
rs13333226 lBF = 26.6491   Chr16 : 20,365,654
0.011 0.989 0.001
rs13329952 lBF = 29.1228   Chr16 : 20,366,507
0.009 0.991 0.000
rs11642282 lBF = 0.0866592   Chr16 : 79,058,257
0.009 0.991 0.000
rs2080501 lBF = -0.113713   Chr16 : 49,643,566
0.009 0.991 0.000
rs3729639 lBF = 0.103985   Chr16 : 67,225,501
0.008 0.992 0.000
rs3784943 lBF = -0.0568387   Chr16 : 83,712,435
0.008 0.992 0.000
rs145049847 lBF = 0.00753444   Chr16 : 22,202,002
0.007 0.993 0.000
rs570013781 lBF = 0.0187981   Chr16 : 149,539
0.007 0.993 0.000
rs111285796 lBF = 25.8384   Chr16 : 20,361,087
0.006 0.993 0.001
rs3751812 lBF = 47.8875   Chr16 : 53,818,460
0.006 0.993 0.000
rs77414823 lBF = 0.0156811   Chr16 : 49,982,757
0.006 0.994 0.000
rs12917707 lBF = 27.0521   Chr16 : 20,367,690
0.006 0.994 0.001
rs4293393 lBF = 26.4744   Chr16 : 20,364,588
0.005 0.994 0.001
rs12325192 lBF = 8.86306   Chr16 : 51,488,129
0.006 0.994 0.000
rs113716969 lBF = 0.0125255   Chr16 : 76,846,266
0.006 0.994 0.000
rs6499255 lBF = 0.297466   Chr16 : 69,830,328
0.006 0.994 0.000
rs117147010 lBF = 0.0688777   Chr16 : 12,596,935
0.005 0.995 0.000
rs6500818 lBF = 0.29881   Chr16 : 6,817,375
0.005 0.995 0.000
rs56213767 lBF = 0.62151   Chr16 : 15,379,572
0.005 0.995 0.000
rs41472047 lBF = 0.00012948   Chr16 : 80,745,775
0.004 0.995 0.000
rs3743714 lBF = -0.0087003   Chr16 : 66,583,705
0.004 0.995 0.000
rs117208012 lBF = 0.365036   Chr16 : 347,063
0.004 0.995 0.000
rs17831015 lBF = -0.0997987   Chr16 : 24,621,348
0.004 0.995 0.000
rs7202116 lBF = 47.5465   Chr16 : 53,821,615
0.004 0.996 0.000
rs11074782 lBF = -0.113182   Chr16 : 26,505,011
0.004 0.996 0.000
rs12598815 lBF = 0.013489   Chr16 : 82,848,208
0.004 0.996 0.000
rs34286592 lBF = 0.631949   Chr16 : 29,820,480
0.003 0.996 0.000
rs13335336 lBF = 0.0144653   Chr16 : 10,559,263
0.003 0.996 0.000
rs74249525 lBF = 0.18106   Chr16 : 83,447,271
0.003 0.997 0.000
rs4527026 lBF = 0.00365789   Chr16 : 19,960,320
0.003 0.997 0.000
rs149133508 lBF = 0.140559   Chr16 : 34,850,618
0.003 0.997 0.000
rs560947 lBF = -0.0903424   Chr16 : 3,185,737
0.001 0.997 0.003
rs7191751 lBF = -0.067992   Chr16 : 86,304,261
0.003 0.997 0.000
rs1801275 lBF = -0.0517617   Chr16 : 27,374,400
0.003 0.997 0.000
rs9928486 lBF = 0.00015953   Chr16 : 24,088,176
0.003 0.997 0.000
rs17817964 lBF = 47.4145   Chr16 : 53,828,066
0.003 0.997 0.000
rs78867184 lBF = -0.0150379   Chr16 : 78,335,044
0.003 0.997 0.000
rs150196149 lBF = 8.52422   Chr16 : 90,126,993
0.002 0.997 0.000
rs192917960 lBF = 0.00220954   Chr16 : 5,919,655
0.002 0.997 0.000
rs9938585 lBF = -0.00002905   Chr16 : 24,085,201
0.002 0.997 0.000
rs8050136 lBF = 48.0125   Chr16 : 53,816,275
0.002 0.998 0.000
rs4465599 lBF = 3.2933   Chr16 : 13,154,878
0.002 0.998 0.000
rs147774538 lBF = 0.202063   Chr16 : 10,372,520
0.002 0.998 0.000
rs79900961 lBF = 0.00797861   Chr16 : 9,297,812
0.002 0.998 0.000
rs8060598 lBF = 0.44141   Chr16 : 50,781,802
0.002 0.998 0.000
rs62033400 lBF = 46.7329   Chr16 : 53,811,788
0.002 0.998 0.000
rs728571 lBF = 2.30158   Chr16 : 55,214,093
0.002 0.998 0.000
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rs10521114 lBF = 0.0406485   Chr16 : 20,089,754
0.000 0.999 0.001
rs16948876 lBF = 0.0243057   Chr16 : 50,854,418
0.000 0.999 0.000
rs141854787 lBF = 0.0178056   Chr16 : 49,786,258
0.000 0.999 0.000
rs17184291 lBF = 0.012679   Chr16 : 81,161,295
0.001 0.999 0.000
rs4082514 lBF = -0.00350218   Chr16 : 82,379,953
0.000 0.999 0.000
rs1064524 lBF = -0.0399583   Chr16 : 30,492,823
0.000 0.999 0.000
rs35063026 lBF = 89.534   Chr16 : 89,736,157
0.000 0.999 0.000
rs60675007 lBF = 10.4312   Chr16 : 83,018,052
0.000 0.999 0.000
rs4782321 lBF = 6.0256   Chr16 : 88,780,175
0.001 0.999 0.000
rs12934187 lBF = 2.18476   Chr16 : 13,845,719
0.000 0.999 0.000
rs1895518 lBF = 0.0972942   Chr16 : 64,904,722
0.000 0.999 0.000
rs4787483 lBF = 0.0630491   Chr16 : 29,885,447
0.001 0.999 0.000
rs9788927 lBF = 0.0479818   Chr16 : 7,929,828
0.001 0.999 0.000
rs8046312 lBF = 0.0342471   Chr16 : 19,979,334
0.001 0.999 0.000
rs7192086 lBF = 0.0104938   Chr16 : 13,061,611
0.001 0.999 0.000
rs12923781 lBF = 0.00842526   Chr16 : 71,653,464
0.001 0.999 0.000
rs137967137 lBF = -0.00184843   Chr16 : 80,467,193
0.000 0.999 0.000
rs3213758 lBF = -0.0227134   Chr16 : 53,639,438
0.000 0.999 0.000
rs17789174 lBF = -0.0686163   Chr16 : 85,103,885
0.000 0.999 0.001
rs1968499 lBF = 29.5683   Chr16 : 89,683,240
0.000 0.999 0.000
rs11642231 lBF = 17.8952   Chr16 : 89,608,702
0.000 0.999 0.000
rs77576048 lBF = 9.88924   Chr16 : 90,078,724
0.000 0.999 0.000
rs36107265 lBF = 5.41624   Chr16 : 49,785,096
0.000 0.999 0.000
rs4888383 lBF = 5.39799   Chr16 : 75,386,349
0.000 0.999 0.000
rs1397142 lBF = 0.222403   Chr16 : 9,343,347
0.001 0.999 0.000
rs246234 lBF = 0.0893087   Chr16 : 16,128,742
0.000 0.999 0.000
rs1906060 lBF = 0.00633283   Chr16 : 6,108,430
0.001 0.999 0.000
rs16976587 lBF = -0.00254265   Chr16 : 27,214,984
0.000 0.999 0.000
rs6499766 lBF = -0.0416222   Chr16 : 55,604,128
0.000 0.999 0.001
rs4787484 lBF = -0.0491076   Chr16 : 29,906,546
0.001 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.9832
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.9786
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.9663
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.9625
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.9601
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.9479
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.9425
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.9411
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.9332
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.9327
Cluster X0113
log Bayes Factor = 49.7598
contains 3 variants
0.9308
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.9269
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.9259
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.9228
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.9207
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.9205
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.9159
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.9145
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.9125
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.9089
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.9073
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.9052
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.9039
Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.8920
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.8912
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.8910
Cluster X0128
log Bayes Factor = 148.918
contains 15 variants
0.8910
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.8891
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.8867
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.8847
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.8804
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.8772
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.8767
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.8733
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.8730
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.8692
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.8681
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.8653
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.8576
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.8556
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.8541
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.8515
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.8495
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.8491
Cluster X0125
log Bayes Factor = 215.738
contains 7 variants
0.8444
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.8423
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.8394
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.8375
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.8357
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.8304
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.8290
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.8229
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.8220
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.8122
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.8117
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.8090
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.8069
Cluster X0278
log Bayes Factor = 173.437
contains 11 variants
0.8041
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.8029
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.8024
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.8024
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.7996
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.7883
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.7861
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.7791
Cluster X0062
log Bayes Factor = 68.7461
contains 4 variants
0.7781
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.7730
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.7730
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.7725
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.7693
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.7689
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.7677
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.7658
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.7631
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.7630
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.7627
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.7564
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.7553
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.7548
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.7535
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.7524
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.7500
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.7485
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.7468
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.7444
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.7394
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.7374
Cluster X0279
log Bayes Factor = 52.8832
contains 2 variants
0.7368
Cluster X0269
log Bayes Factor = 155.455
contains 9 variants
0.7355
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.7343
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.7317
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.7315
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.7312
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.7293
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.7283
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.7274
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.7266
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.7245
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.7233
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.7213
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.7201
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.7197
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.7174
Cluster X0016
log Bayes Factor = 246.869
contains 16 variants
0.7162
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.7142
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.7139
Cluster X0195
log Bayes Factor = 167.337
contains 13 variants
0.7130
Cluster X0193
log Bayes Factor = 303.265
contains 16 variants
0.7127
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.7094
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.7093
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.7066
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.7061
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.7024
Cluster X0315
log Bayes Factor = 42.686
contains 2 variants
0.7014
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.7008
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.6999
Cluster X0267
log Bayes Factor = 92.4806
contains 5 variants
0.6997
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.6983
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.6981
Cluster X0160
log Bayes Factor = 99.5328
contains 9 variants
0.6938
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.6934
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.6931
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.6919
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.6907
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.6892
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.6891
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.6840
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.6829
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.6820
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.6818
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.6815
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.6802
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.6793
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.6743
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.6728
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.6693
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.6640
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.6636
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.6629
Cluster X0173
log Bayes Factor = 654.164
contains 9 variants
0.6622
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.6608
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.6583
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.6554
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.6548
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.6547
Cluster X0244
log Bayes Factor = 122.647
contains 5 variants
0.6506
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.6499
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.6473
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.6460
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.6449
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.6446
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.6441
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.6383
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.6367
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.6354
Cluster X0225
log Bayes Factor = 36.4143
contains 3 variants
0.6309
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.6251
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.6240
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.6233
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.6205
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.6205
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.6197
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.6171
Cluster X0002
log Bayes Factor = 522.044
contains 22 variants
0.6163
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.6162
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.6155
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.6128
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.6120
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.6085
Cluster X0127
log Bayes Factor = 276.004
contains 14 variants
0.6079
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.6075
Cluster X0230
log Bayes Factor = 131.696
contains 7 variants
0.6050
Cluster X0147
log Bayes Factor = 133.509
contains 9 variants
0.6044
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.6042
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.6033
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.5996
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.5980
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.5948
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.5944
Cluster X0101
log Bayes Factor = 45.9023
contains 7 variants
0.5943
Cluster X0247
log Bayes Factor = 98.6507
contains 6 variants
0.5939
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.5930
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.5923
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.5915
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.5898
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.5888
Cluster X0065
log Bayes Factor = 53.0717
contains 3 variants
0.5882
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.5873
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.5869
Cluster X0219
log Bayes Factor = 230.324
contains 15 variants
0.5850
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.5824
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.5821
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.5792
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.5789
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.5789
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.5781
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.5780
Cluster X0223
log Bayes Factor = 122.347
contains 7 variants
0.5751
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.5725
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.5708
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.5663
Cluster X0199
log Bayes Factor = 350.038
contains 3 variants
0.5657
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.5635
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.5578
Cluster X0092
log Bayes Factor = 90.0773
contains 8 variants
0.5541
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.5539
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.5461
Cluster X0301
log Bayes Factor = 297.489
contains 2 variants
0.5451
Cluster X0273
log Bayes Factor = 109.896
contains 6 variants
0.5388
Cluster X0303
log Bayes Factor = 29.6251
contains 3 variants
0.5329
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.5250
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.5225
Cluster X0103
log Bayes Factor = 194.456
contains 13 variants
0.5217
Cluster X0270
log Bayes Factor = 41.2082
contains 4 variants
0.5171
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.5139
Cluster X0328
log Bayes Factor = 380.087
contains 8 variants
0.5095
Cluster X0004
log Bayes Factor = 32.8452
contains 2 variants
0.5022
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.4959
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.4930
Cluster X0228
log Bayes Factor = 196.521
contains 11 variants
0.4927
Cluster X0234
log Bayes Factor = 28.8983
contains 2 variants
0.4896
Cluster X0196
log Bayes Factor = 301.726
contains 18 variants
0.4825
Cluster X0035
log Bayes Factor = 620.567
contains 37 variants
0.4719
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.4657
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.4629
Cluster X0190
log Bayes Factor = 15.3889
contains 2 variants
0.4601
Cluster X0294
log Bayes Factor = 25.2869
contains 2 variants
0.4595
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.4094
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.3972
Cluster X0179
log Bayes Factor = 426.274
contains 17 variants
0.3856
Cluster X0211
log Bayes Factor = 15.2995
contains 2 variants
0.3271
Cluster X0324
log Bayes Factor = 32.1341
contains 1 variants
0.3240
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.3009
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.2804
Cluster X0172
log Bayes Factor = 80.2701
contains 3 variants
0.2357
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.2238
Cluster X0198
log Bayes Factor = 97.078
contains 5 variants
0.2035
Cluster X0314
log Bayes Factor = 92.7289
contains 4 variants
0.1550
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.1384
Cluster X0158
log Bayes Factor = 41.0301
contains 1 variants
0.0909
Cluster X0149
log Bayes Factor = 248.296
contains 10 variants
0.0797
Cluster X0300
log Bayes Factor = 109.684
contains 3 variants
0.0797
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.0765
Cluster X0011
log Bayes Factor = 138.832
contains 11 variants
0.0591
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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