TreeWAS – [M54.5] Low back pain

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs11174454 lBF = `8.97302` Chr`12` : `62,781,002`	0.999	0.001	0.000
rs7305482 lBF = `8.02751` Chr`12` : `62,582,231`	0.999	0.001	0.000
rs2160519 lBF = `9.54207` Chr`12` : `13,787,846`	0.983	0.017	0.000
rs117458579 lBF = `15.4218` Chr`12` : `15,351,989`	0.977	0.023	0.000
rs7307123 lBF = `21.9581` Chr`12` : `54,524,397`	0.973	0.027	0.000
rs11051689 lBF = `13.3747` Chr`12` : `32,084,827`	0.967	0.033	0.000
rs17722134 lBF = `13.8489` Chr`12` : `72,401,694`	0.965	0.035	0.000
rs7299341 lBF = `5.99167` Chr`12` : `83,224,324`	0.964	0.036	0.000
rs12582852 lBF = `14.3759` Chr`12` : `3,315,933`	0.960	0.040	0.000
rs12813285 lBF = `22.3499` Chr`12` : `68,206,219`	0.956	0.044	0.000
rs11179079 lBF = `7.3206` Chr`12` : `72,494,386`	0.954	0.046	0.000
rs12316797 lBF = `1.37316` Chr`12` : `43,160,744`	0.953	0.047	0.000
rs117139804 lBF = `18.4888` Chr`12` : `116,233,671`	0.947	0.053	0.000
rs117761474 lBF = `15.8826` Chr`12` : `113,029,356`	0.946	0.054	0.000
rs10506458 lBF = `2.80462` Chr`12` : `63,445,092`	0.946	0.054	0.000
rs78574971 lBF = `12.9395` Chr`12` : `52,023,925`	0.930	0.070	0.000
rs12821981 lBF = `18.716` Chr`12` : `2,741,217`	0.917	0.083	0.000
rs17813263 lBF = `23.117` Chr`12` : `69,481,381`	0.903	0.097	0.000
rs75876943 lBF = `15.0045` Chr`12` : `86,555,845`	0.902	0.098	0.000
rs117624816 lBF = `14.1981` Chr`12` : `18,210,143`	0.886	0.114	0.000
rs1235153 lBF = `9.04692` Chr`12` : `48,110,325`	0.876	0.124	0.000
rs73200436 lBF = `2.81861` Chr`12` : `110,062,693`	0.875	0.125	0.000
rs117929870 lBF = `16.9839` Chr`12` : `108,524,849`	0.869	0.131	0.000
rs118113273 lBF = `22.5923` Chr`12` : `128,300,100`	0.865	0.135	0.000
rs76409154 lBF = `20.1612` Chr`12` : `85,692,134`	0.840	0.160	0.000
rs1291621 lBF = `15.6995` Chr`12` : `46,340,821`	0.799	0.201	0.000
rs182057829 lBF = `2.49683` Chr`12` : `97,412,327`	0.762	0.238	0.000
rs11059555 lBF = `14.4188` Chr`12` : `128,646,039`	0.721	0.279	0.000
rs7307889 lBF = `7.08994` Chr`12` : `5,981,353`	0.704	0.296	0.000
rs117559199 lBF = `8.42044` Chr`12` : `75,424,551`	0.683	0.317	0.000
rs116962450 lBF = `7.81708` Chr`12` : `90,500,741`	0.679	0.321	0.000
rs80132640 lBF = `11.0963` Chr`12` : `49,426,460`	0.667	0.333	0.000
rs2292303 lBF = `0.924716` Chr`12` : `102,513,531`	0.629	0.371	0.000
rs34934130 lBF = `11.9795` Chr`12` : `121,502,913`	0.615	0.385	0.000
rs6580622 lBF = `15.5075` Chr`12` : `47,936,778`	0.615	0.385	0.000
rs12582659 lBF = `4.82974` Chr`12` : `76,064,528`	0.596	0.404	0.000
rs11044722 lBF = `15.4222` Chr`12` : `19,781,710`	0.585	0.415	0.000
rs117605016 lBF = `28.0976` Chr`12` : `129,614,385`	0.581	0.419	0.000
rs215398 lBF = `19.4313` Chr`12` : `47,767,134`	0.558	0.442	0.000
rs79002142 lBF = `11.7979` Chr`12` : `85,143,591`	0.557	0.443	0.000
rs79015790 lBF = `14.8688` Chr`12` : `128,700,249`	0.556	0.444	0.000
rs59753639 lBF = `4.25806` Chr`12` : `25,140,690`	0.522	0.478	0.000
rs73114523 lBF = `14.6366` Chr`12` : `54,602,032`	0.522	0.478	0.000
rs77662038 lBF = `13.6756` Chr`12` : `83,497,229`	0.521	0.479	0.000
rs61919599 lBF = `9.83827` Chr`12` : `528,351`	0.500	0.500	0.000
rs5742692 lBF = `2.17819` Chr`12` : `102,799,598`	0.499	0.501	0.000
rs75626916 lBF = `11.7941` Chr`12` : `108,663,870`	0.486	0.514	0.000
rs117437287 lBF = `16.5299` Chr`12` : `23,389,839`	0.481	0.519	0.000
rs187353341 lBF = `19.0434` Chr`12` : `121,557,376`	0.474	0.526	0.000
rs118079879 lBF = `5.09035` Chr`12` : `41,713,306`	0.466	0.534	0.000
rs188610 lBF = `2.31323` Chr`12` : `313,839`	0.465	0.535	0.000
rs117303215 lBF = `9.21583` Chr`12` : `129,627,812`	0.460	0.540	0.000
rs73211928 lBF = `9.06643` Chr`12` : `118,039,876`	0.439	0.561	0.000
rs12814941 lBF = `12.4883` Chr`12` : `106,408,172`	0.436	0.564	0.000
rs73217910 lBF = `14.853` Chr`12` : `118,450,865`	0.431	0.569	0.000
rs1386003 lBF = `12.5875` Chr`12` : `13,213,682`	0.428	0.572	0.000
rs61921073 lBF = `6.44028` Chr`12` : `30,660,861`	0.423	0.577	0.000
rs76450399 lBF = `14.1937` Chr`12` : `9,143,781`	0.402	0.598	0.000
rs11108227 lBF = `16.4201` Chr`12` : `96,134,001`	0.401	0.599	0.000
rs12321507 lBF = `16.2879` Chr`12` : `96,134,818`	0.399	0.600	0.000
rs76796201 lBF = `14.1948` Chr`12` : `23,091,755`	0.394	0.606	0.000
rs56269309 lBF = `12.8645` Chr`12` : `127,453,025`	0.391	0.609	0.000
rs12230170 lBF = `6.64286` Chr`12` : `129,247,383`	0.386	0.614	0.000
rs7294372 lBF = `0.932637` Chr`12` : `114,637,423`	0.384	0.616	0.000
rs17432871 lBF = `6.59959` Chr`12` : `121,542,128`	0.377	0.623	0.000
rs77649004 lBF = `14.247` Chr`12` : `96,135,916`	0.373	0.627	0.000
rs17102257 lBF = `14.6206` Chr`12` : `54,126,061`	0.372	0.628	0.000
rs117091826 lBF = `24.5799` Chr`12` : `112,629,713`	0.368	0.632	0.000
rs75489010 lBF = `27.7624` Chr`12` : `115,986,702`	0.352	0.648	0.000
rs77103806 lBF = `6.36663` Chr`12` : `23,021,423`	0.337	0.663	0.000
rs12423747 lBF = `15.1947` Chr`12` : `71,084,299`	0.336	0.664	0.000
Affx-8411664 lBF = `18.4862` Chr`12` : `71,094,955`	0.331	0.669	0.000
rs1653608 lBF = `16.5227` Chr`12` : `121,706,733`	0.327	0.673	0.000
rs150954431 lBF = `0.66025` Chr`12` : `125,002,323`	0.323	0.677	0.000
rs56360506 lBF = `10.2114` Chr`12` : `53,222,800`	0.316	0.684	0.000
rs12304534 lBF = `8.83589` Chr`12` : `89,683,643`	0.314	0.686	0.000
rs10506821 lBF = `13.2804` Chr`12` : `80,496,923`	0.314	0.686	0.000
rs74910874 lBF = `2.61067` Chr`12` : `67,086,810`	0.308	0.692	0.000
rs12423247 lBF = `0.921356` Chr`12` : `96,858,362`	0.306	0.694	0.000
rs191780267 lBF = `4.50227` Chr`12` : `89,289,255`	0.305	0.695	0.000
rs116975820 lBF = `0.223166` Chr`12` : `42,722,908`	0.000	0.703	0.297
rs181609621 lBF = `1.56948` Chr`12` : `32,810,759`	0.289	0.711	0.000
rs2279695 lBF = `6.13321` Chr`12` : `117,154,262`	0.286	0.713	0.000
rs1424609 lBF = `0.0963216` Chr`12` : `116,163,432`	0.286	0.714	0.000
rs143136847 lBF = `1.54314` Chr`12` : `82,748,339`	0.281	0.718	0.000
rs80160299 lBF = `15.0308` Chr`12` : `66,159,224`	0.276	0.723	0.000
rs7975752 lBF = `0.0834701` Chr`12` : `116,154,654`	0.272	0.728	0.000
rs3809128 lBF = `2.10909` Chr`12` : `56,709,919`	0.269	0.730	0.000
rs61943445 lBF = `13.7019` Chr`12` : `118,861,521`	0.261	0.739	0.000
rs111825271 lBF = `10.5466` Chr`12` : `66,344,706`	0.255	0.745	0.000
rs138477082 lBF = `2.62368` Chr`12` : `103,796,611`	0.244	0.756	0.000
rs117557466 lBF = `12.1727` Chr`12` : `69,802,569`	0.242	0.758	0.000
rs17040357 lBF = `13.7026` Chr`12` : `108,665,316`	0.235	0.765	0.000
rs76242156 lBF = `19.5711` Chr`12` : `65,043,774`	0.229	0.771	0.000
rs75311705 lBF = `0.456159` Chr`12` : `125,714,596`	0.227	0.773	0.000
rs141480969 lBF = `0.733874` Chr`12` : `62,496,278`	0.225	0.775	0.000
rs78321382 lBF = `14.0322` Chr`12` : `17,070,922`	0.225	0.775	0.000
rs2417373 lBF = `14.5305` Chr`12` : `14,744,468`	0.224	0.776	0.000
rs11065791 lBF = `12.9532` Chr`12` : `111,460,000`	0.223	0.777	0.000
rs74565952 lBF = `16.1651` Chr`12` : `71,112,797`	0.218	0.782	0.000
rs11175593 lBF = `2.45774` Chr`12` : `40,601,940`	0.214	0.786	0.000
rs12371484 lBF = `19.7008` Chr`12` : `111,872,722`	0.208	0.792	0.000
rs12370770 lBF = `24.384` Chr`12` : `112,277,084`	0.207	0.793	0.000
rs149104283 lBF = `2.00778` Chr`12` : `21,083,862`	0.201	0.799	0.000
rs35729753 lBF = `17.3029` Chr`12` : `66,672,379`	0.198	0.802	0.000
rs79680354 lBF = `22.0763` Chr`12` : `119,361,070`	0.198	0.802	0.000
rs144700679 lBF = `7.09223` Chr`12` : `115,468,959`	0.197	0.802	0.000
rs117863495 lBF = `14.7593` Chr`12` : `129,432,374`	0.186	0.813	0.000
rs73313995 lBF = `22.0276` Chr`12` : `33,622,807`	0.186	0.814	0.000
rs9332958 lBF = `5.25634` Chr`12` : `16,519,263`	0.178	0.822	0.000
rs35446494 lBF = `7.95755` Chr`12` : `119,533,218`	0.177	0.823	0.000
rs115720202 lBF = `18.7627` Chr`12` : `89,746,581`	0.177	0.823	0.000
rs7309269 lBF = `13.6679` Chr`12` : `7,757,834`	0.166	0.833	0.000
rs117759274 lBF = `14.7453` Chr`12` : `23,131,855`	0.165	0.835	0.000
rs11066313 lBF = `14.8578` Chr`12` : `112,893,414`	0.164	0.836	0.000
rs114453043 lBF = `22.0948` Chr`12` : `25,461,756`	0.164	0.836	0.000
rs76775795 lBF = `13.6666` Chr`12` : `115,385,431`	0.162	0.837	0.000
rs78221103 lBF = `16.6479` Chr`12` : `104,562,673`	0.160	0.840	0.000
rs3794288 lBF = `0.216509` Chr`12` : `2,789,221`	0.154	0.846	0.000
rs73141422 lBF = `22.399` Chr`12` : `83,882,469`	0.152	0.847	0.000
rs117439611 lBF = `14.8831` Chr`12` : `520,944`	0.150	0.849	0.001
rs34574480 lBF = `13.3586` Chr`12` : `115,307,567`	0.142	0.858	0.000
rs73164250 lBF = `17.0593` Chr`12` : `84,624,334`	0.141	0.859	0.000
rs112742247 lBF = `13.3959` Chr`12` : `85,030,619`	0.140	0.860	0.000
rs75289085 lBF = `19.4964` Chr`12` : `18,147,653`	0.139	0.861	0.000
rs74911677 lBF = `20.5271` Chr`12` : `122,015,993`	0.136	0.864	0.000
rs993226 lBF = `0.111824` Chr`12` : `84,886,573`	0.133	0.867	0.000
rs12422544 lBF = `1.68441` Chr`12` : `40,528,432`	0.132	0.868	0.000
rs11067763 lBF = `4.33511` Chr`12` : `116,198,341`	0.131	0.869	0.000
rs12310380 lBF = `8.99711` Chr`12` : `104,478,790`	0.126	0.874	0.000
rs3217863 lBF = `9.55969` Chr`12` : `4,399,496`	0.123	0.877	0.000
rs3751143 lBF = `0.142268` Chr`12` : `121,622,304`	0.000	0.879	0.121
rs116877397 lBF = `30.7668` Chr`12` : `121,162,996`	0.121	0.879	0.000
rs117629949 lBF = `14.77` Chr`12` : `25,021,224`	0.119	0.881	0.000
rs76595471 lBF = `13.0273` Chr`12` : `80,228,443`	0.116	0.884	0.000
rs76001134 lBF = `19.3411` Chr`12` : `23,209,903`	0.115	0.885	0.000
rs116938548 lBF = `0.178688` Chr`12` : `4,808,251`	0.108	0.892	0.000
rs117409850 lBF = `13.4266` Chr`12` : `106,057,582`	0.100	0.899	0.001
rs78008978 lBF = `13.3787` Chr`12` : `77,282,680`	0.098	0.901	0.000
rs117825839 lBF = `16.5381` Chr`12` : `28,978,196`	0.096	0.904	0.000
rs73201485 lBF = `11.279` Chr`12` : `114,791,319`	0.091	0.909	0.000
rs117802803 lBF = `21.4181` Chr`12` : `22,796,804`	0.090	0.910	0.000
rs80002652 lBF = `18.6612` Chr`12` : `107,437,422`	0.088	0.912	0.001
rs192051543 lBF = `14.1247` Chr`12` : `22,657,770`	0.086	0.914	0.000
rs11611673 lBF = `13.5862` Chr`12` : `121,451,150`	0.083	0.917	0.000
rs144288546 lBF = `0.146461` Chr`12` : `129,069,682`	0.082	0.918	0.000
rs199710891 lBF = `5.87106` Chr`12` : `14,273,071`	0.080	0.919	0.000
rs117089640 lBF = `23.0292` Chr`12` : `125,048,557`	0.079	0.921	0.000
rs117636037 lBF = `18.8537` Chr`12` : `38,519,375`	0.071	0.929	0.000
rs12308914 lBF = `12.8877` Chr`12` : `104,633,842`	0.071	0.929	0.000
rs2172873 lBF = `0.108565` Chr`12` : `103,125,690`	0.068	0.932	0.000
rs2900174 lBF = `7.38903` Chr`12` : `11,547,532`	0.066	0.934	0.000
rs74452899 lBF = `12.3113` Chr`12` : `89,024,239`	0.064	0.936	0.000
rs12823357 lBF = `6.08625` Chr`12` : `55,473,859`	0.063	0.937	0.000
rs11608709 lBF = `15.4681` Chr`12` : `99,302,859`	0.060	0.940	0.000
rs111341849 lBF = `13.9983` Chr`12` : `83,961,998`	0.057	0.943	0.000
rs2722223 lBF = `24.9818` Chr`12` : `90,233,876`	0.056	0.943	0.000
rs11060736 lBF = `-0.0122292` Chr`12` : `130,630,935`	0.056	0.944	0.000
rs12423712 lBF = `0.0543282` Chr`12` : `125,033,933`	0.056	0.944	0.000
rs2089222 lBF = `1.58966` Chr`12` : `117,002,658`	0.056	0.944	0.000
rs16914920 lBF = `12.1807` Chr`12` : `19,128,595`	0.055	0.945	0.000
rs117138325 lBF = `14.5458` Chr`12` : `74,850,188`	0.053	0.947	0.000
rs4149639 lBF = `0.234732` Chr`12` : `6,442,001`	0.052	0.947	0.000
rs78294386 lBF = `14.58` Chr`12` : `107,963,652`	0.051	0.949	0.000
rs111969502 lBF = `5.3967` Chr`12` : `59,848,381`	0.051	0.949	0.000
rs76191003 lBF = `9.4885` Chr`12` : `47,182,531`	0.051	0.949	0.000
rs5744807 lBF = `13.1175` Chr`12` : `133,243,621`	0.050	0.950	0.000
rs71454665 lBF = `8.54321` Chr`12` : `121,198,711`	0.049	0.951	0.000
rs703556 lBF = `0.0322573` Chr`12` : `103,011,894`	0.045	0.955	0.000
rs117470014 lBF = `18.6761` Chr`12` : `74,652,195`	0.044	0.956	0.000
rs78437391 lBF = `22.4064` Chr`12` : `129,229,615`	0.043	0.957	0.000
rs12425131 lBF = `16.2355` Chr`12` : `82,984,879`	0.041	0.958	0.000
rs2011738 lBF = `-0.0563275` Chr`12` : `219,988`	0.041	0.959	0.000
rs79918060 lBF = `17.5524` Chr`12` : `58,407,669`	0.040	0.959	0.001
rs17528414 lBF = `17.7734` Chr`12` : `32,352,055`	0.037	0.963	0.000
rs17443266 lBF = `15.2354` Chr`12` : `19,169,453`	0.036	0.964	0.000
rs117291831 lBF = `7.6951` Chr`12` : `127,045,967`	0.035	0.965	0.000
rs16906714 lBF = `0.0571485` Chr`12` : `30,860,557`	0.034	0.966	0.000
rs4238083 lBF = `14.8083` Chr`12` : `42,924,769`	0.033	0.967	0.000
rs61756485 lBF = `16.787` Chr`12` : `99,020,125`	0.033	0.967	0.000
rs12322695 lBF = `0.0399753` Chr`12` : `117,199,414`	0.032	0.968	0.000
rs7298767 lBF = `17.6072` Chr`12` : `22,475,701`	0.030	0.969	0.001
rs766903 lBF = `0.131364` Chr`12` : `51,703,834`	0.028	0.972	0.000
rs76270203 lBF = `1.90441` Chr`12` : `113,936,996`	0.028	0.972	0.000
rs11115322 lBF = `13.8059` Chr`12` : `83,019,188`	0.026	0.974	0.000
rs187986843 lBF = `15.061` Chr`12` : `69,080,770`	0.026	0.974	0.000
rs11837432 lBF = `16.9657` Chr`12` : `2,170,893`	0.025	0.974	0.001
rs77821460 lBF = `20.1742` Chr`12` : `20,274,936`	0.025	0.974	0.001
rs10777534 lBF = `5.44821` Chr`12` : `94,084,878`	0.025	0.975	0.000
rs871392 lBF = `0.133655` Chr`12` : `42,171,982`	0.022	0.978	0.000
rs77572683 lBF = `7.85519` Chr`12` : `114,261,767`	0.021	0.979	0.000
rs78851502 lBF = `8.34221` Chr`12` : `40,811,944`	0.021	0.979	0.000
rs79476482 lBF = `14.9329` Chr`12` : `76,084,550`	0.020	0.980	0.000
rs75593565 lBF = `13.6234` Chr`12` : `32,115,266`	0.019	0.980	0.001
rs117029533 lBF = `21.9889` Chr`12` : `66,632,067`	0.018	0.981	0.001
rs188255132 lBF = `0.0230843` Chr`12` : `81,723,188`	0.018	0.981	0.000
rs116910038 lBF = `0.0694182` Chr`12` : `85,424,093`	0.018	0.982	0.000
rs2708377 lBF = `0.00974402` Chr`12` : `11,216,315`	0.000	0.982	0.018
rs11609031 lBF = `16.3836` Chr`12` : `99,307,725`	0.018	0.982	0.000
rs7313075 lBF = `-0.0257493` Chr`12` : `102,630,679`	0.017	0.983	0.000
rs936332 lBF = `-0.0514097` Chr`12` : `52,640,277`	0.017	0.983	0.000
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rs193153567 lBF = `-0.00029294` Chr`12` : `48,946,231`	0.001	0.999	0.000
rs11183298 lBF = `-0.0871086` Chr`12` : `46,432,590`	0.000	0.999	0.001
rs7136572 lBF = `-0.00402774` Chr`12` : `95,959,788`	0.001	0.999	0.000
rs4763879 lBF = `7.5082` Chr`12` : `9,910,164`	0.000	0.999	0.001
rs4251424 lBF = `-0.00048778` Chr`12` : `44,153,826`	0.001	0.999	0.000
rs258415 lBF = `1.25111` Chr`12` : `28,017,522`	0.000	0.999	0.001
rs11183296 lBF = `-0.0927706` Chr`12` : `46,426,737`	0.000	0.999	0.001
rs7965445 lBF = `-0.0195556` Chr`12` : `131,862,903`	0.000	0.999	0.001
rs1151008 lBF = `-0.120747` Chr`12` : `32,097,360`	0.000	0.999	0.001
rs4149056 lBF = `-0.0420678` Chr`12` : `21,331,549`	0.001	0.999	0.000
rs11052552 lBF = `6.57279` Chr`12` : `9,855,958`	0.000	0.999	0.001
rs139680557 lBF = `0.0111233` Chr`12` : `108,061,589`	0.000	0.999	0.001
rs59448276 lBF = `-0.00012332` Chr`12` : `52,680,766`	0.000	0.999	0.000
rs17539289 lBF = `-0.0209531` Chr`12` : `41,126,330`	0.001	0.999	0.000
rs3764021 lBF = `5.72645` Chr`12` : `9,833,628`	0.001	0.999	0.000
rs1167125 lBF = `0.204614` Chr`12` : `43,434,282`	0.000	0.999	0.001
rs373374 lBF = `9.61442` Chr`12` : `52,880,007`	0.001	0.999	0.000
rs17108344 lBF = `-0.00155388` Chr`12` : `70,954,464`	0.000	0.999	0.000
rs79946301 lBF = `-0.00185935` Chr`12` : `130,117,149`	0.000	0.999	0.001
rs117483990 lBF = `-0.00680357` Chr`12` : `90,224,714`	0.001	0.999	0.000
rs11109142 lBF = `-0.00930259` Chr`12` : `98,027,691`	0.000	0.999	0.001
rs4149584 lBF = `-0.0194945` Chr`12` : `6,442,643`	0.000	0.999	0.001
rs11829119 lBF = `-0.0240856` Chr`12` : `19,193,531`	0.001	0.999	0.000
rs7979673 lBF = `0.00145938` Chr`12` : `66,227,257`	0.001	0.999	0.000
rs2268118 lBF = `-0.0181373` Chr`12` : `13,872,044`	0.001	0.999	0.000
rs12231974 lBF = `6.07834` Chr`12` : `67,095,378`	0.001	0.999	0.000
rs187607716 lBF = `0.281898` Chr`12` : `91,487,517`	0.000	0.999	0.000
rs708886 lBF = `-0.0958841` Chr`12` : `119,958,702`	0.001	0.999	0.000
rs370354 lBF = `10.0787` Chr`12` : `52,862,041`	0.001	0.999	0.000
rs1485394 lBF = `0.454763` Chr`12` : `53,955,485`	0.001	0.999	0.000
rs2229774 lBF = `0.221118` Chr`12` : `53,605,545`	0.000	0.999	0.001
rs4326844 lBF = `0.0234596` Chr`12` : `54,736,470`	0.000	0.999	0.001
rs186879571 lBF = `0.0106335` Chr`12` : `128,652,831`	0.000	0.999	0.000
rs11177669 lBF = `-0.00206854` Chr`12` : `69,828,681`	0.000	0.999	0.001
rs76177788 lBF = `0.0120066` Chr`12` : `86,544,239`	0.000	0.999	0.000
rs187035304 lBF = `0.00715419` Chr`12` : `87,229,742`	0.000	0.999	0.000
rs144148493 lBF = `0.015726` Chr`12` : `87,360,221`	0.000	0.999	0.000
rs143888465 lBF = `0.00254406` Chr`12` : `52,010,108`	0.000	0.999	0.001
rs12811699 lBF = `0.0495048` Chr`12` : `105,017,164`	0.000	0.999	0.000
rs1048497 lBF = `0.0465065` Chr`12` : `124,499,542`	0.000	0.999	0.001
rs499368 lBF = `-0.00108169` Chr`12` : `320,920`	0.000	0.999	0.000
rs10778560 lBF = `0.0420953` Chr`12` : `107,801,401`	0.001	0.999	0.000
rs1795708 lBF = `0.00830607` Chr`12` : `58,750,680`	0.000	0.999	0.001
rs10772644 lBF = `-0.0392366` Chr`12` : `13,417,617`	0.000	0.999	0.001
rs10877839 lBF = `-0.0977914` Chr`12` : `62,818,481`	0.000	0.999	0.001
rs4930776 lBF = `-0.12119` Chr`12` : `5,767,385`	0.000	0.999	0.001
rs117839344 lBF = `8.17878` Chr`12` : `58,183,636`	0.000	0.999	0.000
rs147845115 lBF = `0.0739711` Chr`12` : `51,878,760`	0.000	0.999	0.000
rs11044946 lBF = `0.0504246` Chr`12` : `20,081,335`	0.001	0.999	0.000
rs79843055 lBF = `0.00066378` Chr`12` : `86,284,459`	0.000	0.999	0.000
rs2016266 lBF = `0.0818226` Chr`12` : `53,727,955`	0.000	0.999	0.001
rs11564258 lBF = `0.0464349` Chr`12` : `40,792,300`	0.001	0.999	0.000
rs1727313 lBF = `4.61449` Chr`12` : `123,640,853`	0.001	0.999	0.000
rs7304057 lBF = `0.0675331` Chr`12` : `131,352,562`	0.001	0.999	0.000
rs187039407 lBF = `0.0120709` Chr`12` : `87,341,774`	0.000	0.999	0.000
rs73040424 lBF = `7.46879` Chr`12` : `5,665,454`	0.000	0.999	0.001
rs77628219 lBF = `0.0129624` Chr`12` : `87,404,130`	0.000	0.999	0.000
rs17019682 lBF = `-0.0237381` Chr`12` : `92,305,270`	0.001	0.999	0.000
rs57551647 lBF = `6.18396` Chr`12` : `85,602,577`	0.001	0.999	0.000
rs2343873 lBF = `0.0466979` Chr`12` : `26,404,298`	0.001	0.999	0.000
rs11175194 lBF = `-0.0229417` Chr`12` : `64,264,837`	0.000	0.999	0.001
rs142054194 lBF = `0.0063675` Chr`12` : `86,864,240`	0.000	0.999	0.000
rs7970953 lBF = `-0.0693781` Chr`12` : `24,075,508`	0.000	0.999	0.001
rs10744816 lBF = `0.0401009` Chr`12` : `114,714,266`	0.000	0.999	0.001
rs140444490 lBF = `0.00607512` Chr`12` : `86,860,976`	0.000	0.999	0.000
rs7315438 lBF = `-0.0104322` Chr`12` : `115,891,403`	0.000	0.999	0.001
rs404443 lBF = `10.1143` Chr`12` : `52,860,609`	0.001	0.999	0.000
rs10876550 lBF = `0.0278901` Chr`12` : `54,712,308`	0.000	0.999	0.001
rs150695384 lBF = `0.0114384` Chr`12` : `64,917,042`	0.000	0.999	0.000
rs17291650 lBF = `-0.0237825` Chr`12` : `51,213,433`	0.001	0.999	0.000
rs145863439 lBF = `1.25684` Chr`12` : `800,834`	0.000	1.000	0.000
rs1882496 lBF = `-0.00032723` Chr`12` : `104,900,584`	0.000	1.000	0.000
rs10848820 lBF = `-0.00858932` Chr`12` : `3,296,948`	0.000	1.000	0.000
rs16923647 lBF = `-0.0674625` Chr`12` : `21,451,395`	0.000	1.000	0.000
rs11112046 lBF = `0.314989` Chr`12` : `104,818,192`	0.000	1.000	0.000
rs2272046 lBF = `0.0593854` Chr`12` : `66,224,461`	0.000	1.000	0.000
rs12321906 lBF = `-0.00389599` Chr`12` : `53,916,715`	0.000	1.000	0.000
rs11047102 lBF = `0.427704` Chr`12` : `23,946,146`	0.000	1.000	0.000
rs1559997 lBF = `-0.016814` Chr`12` : `113,847,542`	0.000	1.000	0.000
rs3764044 lBF = `-0.0323613` Chr`12` : `21,428,371`	0.000	1.000	0.000
rs10748180 lBF = `0.0453805` Chr`12` : `72,071,045`	0.000	1.000	0.000
rs11055387 lBF = `-0.012726` Chr`12` : `13,519,996`	0.000	1.000	0.000
rs7968270 lBF = `-0.0660084` Chr`12` : `95,095,838`	0.000	1.000	0.000
rs12319113 lBF = `0.0238283` Chr`12` : `19,024,558`	0.000	1.000	0.000
rs1388585 lBF = `0.675794` Chr`12` : `40,531,691`	0.000	1.000	0.000
rs1463605 lBF = `0.00786643` Chr`12` : `30,113,883`	0.000	1.000	0.000
rs4883201 lBF = `-0.0580715` Chr`12` : `9,082,581`	0.000	1.000	0.000
rs10774625 lBF = `134.733` Chr`12` : `111,910,219`	0.000	1.000	0.000
rs76569837 lBF = `0.00029194` Chr`12` : `45,959,763`	0.000	1.000	0.000
rs1727307 lBF = `1.1457` Chr`12` : `123,575,742`	0.000	1.000	0.000
rs7296418 lBF = `0.557974` Chr`12` : `123,457,619`	0.000	1.000	0.000
rs7294919 lBF = `0.090446` Chr`12` : `117,327,592`	0.000	1.000	0.000
rs2384207 lBF = `0.154401` Chr`12` : `113,607,502`	0.000	1.000	0.000
rs275380 lBF = `-0.0100521` Chr`12` : `43,929,996`	0.000	1.000	0.000
rs10784285 lBF = `0.518979` Chr`12` : `62,558,314`	0.000	1.000	0.000
rs10773971 lBF = `-0.0157233` Chr`12` : `1,740,171`	0.000	1.000	0.000
rs10848911 lBF = `-0.0331332` Chr`12` : `3,814,238`	0.000	1.000	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

1.0000

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

1.0000

Cluster X0165

log Bayes Factor = 303.727

contains 12 variants

1.0000

Cluster X0059

log Bayes Factor = 922.497

contains 26 variants

1.0000

Cluster X0085

log Bayes Factor = 138.902

contains 6 variants

0.9999

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

0.9999

Cluster X0001

log Bayes Factor = 167.541

contains 7 variants

0.9998

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

0.9998

Cluster X0163

log Bayes Factor = 122.554

contains 6 variants

0.9998

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

0.9998

Cluster X0153

log Bayes Factor = 328.394

contains 11 variants

0.9997

Cluster X0191

log Bayes Factor = 163.555

contains 8 variants

0.9997

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

0.9997

Cluster X0102

log Bayes Factor = 99.5678

contains 5 variants

0.9993

Cluster X0156

log Bayes Factor = 226.954

contains 9 variants

0.9990

Cluster X0237

log Bayes Factor = 123.902

contains 6 variants

0.9982

Cluster X0324

log Bayes Factor = 32.1341

contains 1 variants

0.9982

Cluster X0211

log Bayes Factor = 15.2995

contains 2 variants

0.9968

Cluster X0052

log Bayes Factor = 654.387

contains 25 variants

0.9968

Cluster X0160

log Bayes Factor = 99.5328

contains 9 variants

0.9966

Cluster X0133

log Bayes Factor = 224.204

contains 11 variants

0.9952

Cluster X0256

log Bayes Factor = 211.588

contains 9 variants

0.9952

Cluster X0041

log Bayes Factor = 306.192

contains 14 variants

0.9947

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

0.9938

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

0.9926

Cluster X0045

log Bayes Factor = 446.264

contains 16 variants

0.9903

Cluster X0013

log Bayes Factor = 548.265

contains 23 variants

0.9900

Cluster X0152

log Bayes Factor = 331.156

contains 10 variants

0.9873

Cluster X0080

log Bayes Factor = 455.123

contains 21 variants

0.9843

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

0.9841

Cluster X0249

log Bayes Factor = 244.457

contains 11 variants

0.9821

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

0.9804

Cluster X0320

log Bayes Factor = 110.964

contains 6 variants

0.9759

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

0.9757

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

0.9659

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

0.9627

Cluster X0029

log Bayes Factor = 709.102

contains 23 variants

0.9622

Cluster X0075

log Bayes Factor = 431.344

contains 16 variants

0.9606

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

0.9545

Cluster X0274

log Bayes Factor = 454.783

contains 18 variants

0.9536

Cluster X0284

log Bayes Factor = 192.532

contains 9 variants

0.9516

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

0.9495

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

0.9449

Cluster X0021

log Bayes Factor = 338.631

contains 13 variants

0.9366

Cluster X0257

log Bayes Factor = 281.184

contains 10 variants

0.9227

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

0.9178

Cluster X0100

log Bayes Factor = 730.252

contains 26 variants

0.9055

Cluster X0208

log Bayes Factor = 40.6733

contains 2 variants

0.8988

Cluster X0332

log Bayes Factor = 65.2374

contains 3 variants

0.8926

Cluster X0120

log Bayes Factor = 79.6695

contains 4 variants

0.8845

Cluster X0193

log Bayes Factor = 303.265

contains 16 variants

0.8788

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

0.8763

Cluster X0279

log Bayes Factor = 52.8832

contains 2 variants

0.8762

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

0.8607

Cluster X0067

log Bayes Factor = 179.381

contains 8 variants

0.8580

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

0.7942

Cluster X0038

log Bayes Factor = 31.1234

contains 2 variants

0.7712

Cluster X0147

log Bayes Factor = 133.509

contains 9 variants

0.7424

Cluster X0014

log Bayes Factor = 131.677

contains 6 variants

0.7407

Cluster X0047

log Bayes Factor = 378.621

contains 14 variants

0.7192

Cluster X0081

log Bayes Factor = 278.568

contains 10 variants

0.7160

Cluster X0063

log Bayes Factor = 107.557

contains 5 variants

0.7078

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

0.7060

Cluster X0301

log Bayes Factor = 297.489

contains 2 variants

0.6972

Cluster X0188

log Bayes Factor = 222.629

contains 14 variants

0.6951

Cluster X0220

log Bayes Factor = 142.284

contains 7 variants

0.6851

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

0.6718

Cluster X0061

log Bayes Factor = 293.105

contains 15 variants

0.6560

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

0.6125

Cluster X0243

log Bayes Factor = 104.974

contains 6 variants

0.5979

Cluster X0095

log Bayes Factor = 179.348

contains 8 variants

0.5620

Cluster X0078

log Bayes Factor = 203.49

contains 11 variants

0.5368

Cluster X0214

log Bayes Factor = 186.582

contains 8 variants

0.5246

Cluster X0048

log Bayes Factor = 358.819

contains 19 variants

0.5242

Cluster X0088

log Bayes Factor = 243.609

contains 9 variants

0.5156

Cluster X0101

log Bayes Factor = 45.9023

contains 7 variants

0.5142

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

0.5075

Cluster X0293

log Bayes Factor = 169.051

contains 7 variants

0.4329

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

0.4216

Cluster X0185

log Bayes Factor = 84.7127

contains 6 variants

0.4051

Cluster X0132

log Bayes Factor = 267.393

contains 11 variants

0.4039

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

0.4000

Cluster X0157

log Bayes Factor = 172.957

contains 8 variants

0.3974

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

0.3801

Cluster X0065

log Bayes Factor = 53.0717

contains 3 variants

0.3627

Cluster X0162

log Bayes Factor = 144.479

contains 9 variants

0.3459

Cluster X0224

log Bayes Factor = 278.692

contains 11 variants

0.3366

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

0.3290

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

0.3154

Cluster X0071

log Bayes Factor = 131.269

contains 6 variants

0.2856

Cluster X0070

log Bayes Factor = 421.182

contains 15 variants

0.2834

Cluster X0089

log Bayes Factor = 308.747

contains 13 variants

0.2721

Cluster X0046

log Bayes Factor = 387.972

contains 16 variants

0.2625

Cluster X0263

log Bayes Factor = 240.36

contains 13 variants

0.2597

Cluster X0012

log Bayes Factor = 112.432

contains 5 variants

0.2576

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

0.2374

Cluster X0181

log Bayes Factor = 141.396

contains 6 variants

0.2314

Cluster X0015

log Bayes Factor = 356.23

contains 15 variants

0.2311

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

0.2282

Cluster X0268

log Bayes Factor = 213.591

contains 8 variants

0.2264

Cluster X0110

log Bayes Factor = 721.325

contains 13 variants

0.2222

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

0.2104

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

0.2034

Cluster X0273

log Bayes Factor = 109.896

contains 6 variants

0.1998

Cluster X0230

log Bayes Factor = 131.696

contains 7 variants

0.1895

Cluster X0199

log Bayes Factor = 350.038

contains 3 variants

0.1886

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

0.1878

Cluster X0154

log Bayes Factor = 282.084

contains 12 variants

0.1859

Cluster X0234

log Bayes Factor = 28.8983

contains 2 variants

0.1823

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

0.1808

Cluster X0058

log Bayes Factor = 183.199

contains 8 variants

0.1792

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

0.1783

Cluster X0024

log Bayes Factor = 309.44

contains 13 variants

0.1765

Cluster X0062

log Bayes Factor = 68.7461

contains 4 variants

0.1755

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

0.1648

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

0.1582

Cluster X0244

log Bayes Factor = 122.647

contains 5 variants

0.1568

Cluster X0057

log Bayes Factor = 439.35

contains 16 variants

0.1563

Cluster X0140

log Bayes Factor = 164.536

contains 8 variants

0.1536

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

0.1528

Cluster X0113

log Bayes Factor = 49.7598

contains 3 variants

0.1525

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

0.1524

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

0.1510

Cluster X0222

log Bayes Factor = 431.582

contains 17 variants

0.1490

Cluster X0141

log Bayes Factor = 742.063

contains 30 variants

0.1372

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

0.1359

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

0.1258

Cluster X0248

log Bayes Factor = 254.854

contains 10 variants

0.1201

Cluster X0225

log Bayes Factor = 36.4143

contains 3 variants

0.1173

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

0.1111

Cluster X0109

log Bayes Factor = 257.685

contains 11 variants

0.1100

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

0.1071

Cluster X0210

log Bayes Factor = 426.159

contains 17 variants

0.1053

Cluster X0184

log Bayes Factor = 188.416

contains 8 variants

0.1051

Cluster X0259

log Bayes Factor = 246.237

contains 11 variants

0.0989

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

0.0856

Cluster X0269

log Bayes Factor = 155.455

contains 9 variants

0.0840

Cluster X0294

log Bayes Factor = 25.2869

contains 2 variants

0.0830

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

0.0793

Cluster X0055

log Bayes Factor = 274.911

contains 10 variants

0.0763

Cluster X0189

log Bayes Factor = 149.681

contains 5 variants

0.0711

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

0.0631

Cluster X0170

log Bayes Factor = 264.081

contains 11 variants

0.0622

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

0.0621

Cluster X0084

log Bayes Factor = 433.078

contains 21 variants

0.0569

Cluster X0074

log Bayes Factor = 353.38

contains 15 variants

0.0561

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

0.0502

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	M54 Dorsalgia
Nested terms	M54.50 Low back pain (Multiple sites in spine) M54.51 Low back pain-Occipit-atl-axl M54.52 Low back pain-Cervical M54.53 Low back pain-Cervicothoracic M54.54 Low back pain-Thoracic M54.55 Low back pain (Thoracolumbar region) M54.56 Low back pain (Lumbar region) M54.57 Low back pain (Lumbosacral region) M54.58 Low back pain (Sacral and sacrococcygeal region) M54.59 Low back pain (Site unspecified)

Diagnostic term associations

Hospitalization Episode Statistics (`HES`)

(posterior probability > 0.05)

(posterior probability > 0.05)

Diagnostic term associations

Hospitalization Episode Statistics (HES)

(posterior probability > 0.05)

(posterior probability > 0.05)

Hospitalization Episode Statistics (`HES`)