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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

Q05
Spina bifida
Parent term
Q00-Q07 Congenital malformations of the nervous system
Nested terms
Q05.0 Cervical spina bifida with hydrocephalus
Q05.1 Thoracic spina bifida with hydrocephalus
Q05.2 Lumbar spina bifida with hydrocephalus
Q05.3 Sacral spina bifida with hydrocephalus
Q05.4 Unspecified spina bifida with hydrocephalus
Q05.5 Cervical spina bifida without hydrocephalus
Q05.6 Thoracic spina bifida without hydrocephalus
Q05.7 Lumbar spina bifida without hydrocephalus
Q05.8 Sacral spina bifida without hydrocephalus
Q05.9 Spina bifida, unspecified
What are diagnostic terms?
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs16986856 lBF = 0.891232   Chr19 : 56,497,960
0.809 0.191 0.000
rs2238664 lBF = 17.927   Chr19 : 19,258,385
0.668 0.332 0.000
rs117167710 lBF = 18.286   Chr19 : 49,602,287
0.627 0.372 0.000
rs41289512 lBF = 27.1631   Chr19 : 45,351,516
0.626 0.374 0.000
rs10424702 lBF = 9.34888   Chr19 : 19,508,013
0.585 0.415 0.000
rs67405884 lBF = 19.8101   Chr19 : 50,229,382
0.584 0.416 0.000
rs10415889 lBF = 20.2782   Chr19 : 17,544,165
0.576 0.424 0.000
rs10415849 lBF = 8.12617   Chr19 : 19,505,087
0.575 0.425 0.000
rs117000465 lBF = 9.39806   Chr19 : 31,056,668
0.575 0.425 0.000
rs111785063 lBF = 7.71115   Chr19 : 22,646,085
0.570 0.429 0.000
rs17216525 lBF = 13.7081   Chr19 : 19,662,220
0.545 0.455 0.000
rs117681218 lBF = 15.1496   Chr19 : 21,045,381
0.526 0.473 0.000
rs34457396 lBF = 18.3682   Chr19 : 10,752,352
0.523 0.477 0.000
rs117220821 lBF = 20.7939   Chr19 : 40,402,976
0.523 0.477 0.000
rs10414451 lBF = 9.16924   Chr19 : 58,131,576
0.522 0.478 0.000
rs16996148 lBF = 15.2513   Chr19 : 19,658,472
0.522 0.478 0.000
rs112888289 lBF = 14.8654   Chr19 : 31,600,124
0.521 0.479 0.000
rs112588716 lBF = 10.293   Chr19 : 48,119,266
0.512 0.488 0.000
rs77073981 lBF = 11.9832   Chr19 : 23,235,972
0.500 0.500 0.000
rs8102610 lBF = 18.6414   Chr19 : 22,936,708
0.498 0.502 0.000
rs1799782 lBF = 8.31404   Chr19 : 44,057,574
0.498 0.502 0.000
rs78943781 lBF = 9.83402   Chr19 : 32,443,306
0.497 0.503 0.000
rs9749449 lBF = 5.13742   Chr19 : 58,144,715
0.495 0.505 0.000
rs34034473 lBF = 13.1796   Chr19 : 58,132,106
0.495 0.505 0.000
rs12610185 lBF = 11.2888   Chr19 : 19,721,722
0.494 0.506 0.000
rs34740499 lBF = 11.6308   Chr19 : 1,697,366
0.493 0.507 0.000
rs56003409 lBF = 8.45799   Chr19 : 32,096,558
0.491 0.509 0.000
rs2304130 lBF = 2.86455   Chr19 : 19,789,528
0.490 0.510 0.000
rs73031884 lBF = 12.3771   Chr19 : 31,702,426
0.489 0.511 0.000
rs73033835 lBF = 10.9241   Chr19 : 31,754,001
0.486 0.514 0.000
rs79565709 lBF = 12.3505   Chr19 : 40,832,132
0.482 0.518 0.000
rs74176255 lBF = 6.85732   Chr19 : 7,920,771
0.482 0.518 0.000
rs117216419 lBF = 13.1076   Chr19 : 41,700,346
0.481 0.519 0.000
rs12980573 lBF = 15.9303   Chr19 : 11,434,585
0.479 0.521 0.000
rs17215305 lBF = 12.2436   Chr19 : 19,293,252
0.477 0.522 0.000
rs34265079 lBF = 11.1494   Chr19 : 28,577,342
0.476 0.524 0.000
rs75714869 lBF = 16.8432   Chr19 : 34,236,415
0.472 0.528 0.000
rs77196615 lBF = 18.4565   Chr19 : 45,380,335
0.471 0.529 0.000
rs17741506 lBF = 13.2067   Chr19 : 58,458,516
0.470 0.529 0.000
rs147138724 lBF = 15.3443   Chr19 : 32,582,254
0.468 0.532 0.000
rs11880637 lBF = 3.65485   Chr19 : 11,655,010
0.466 0.534 0.000
rs61736521 lBF = 25.3724   Chr19 : 56,206,311
0.464 0.535 0.000
rs73001065 lBF = 18.1502   Chr19 : 19,460,541
0.464 0.536 0.000
rs138292237 lBF = 14.389   Chr19 : 21,910,125
0.462 0.538 0.000
rs78517764 lBF = 17.5971   Chr19 : 55,055,906
0.461 0.539 0.000
rs3969860 lBF = 18.4227   Chr19 : 11,447,886
0.459 0.541 0.000
rs17887018 lBF = 17.3793   Chr19 : 36,641,563
0.457 0.543 0.000
rs55736564 lBF = 12.1044   Chr19 : 55,180,067
0.453 0.547 0.000
rs200876443 lBF = 17.0144   Chr19 : 50,363,585
0.448 0.552 0.000
rs2238675 lBF = 6.01595   Chr19 : 19,336,608
0.448 0.552 0.000
rs76157865 lBF = 14.4081   Chr19 : 24,169,805
0.444 0.556 0.000
rs111772174 lBF = 12.5098   Chr19 : 2,685,808
0.443 0.556 0.000
rs10401969 lBF = 22.1773   Chr19 : 19,407,718
0.438 0.561 0.000
rs76966440 lBF = 14.1937   Chr19 : 10,797,763
0.437 0.563 0.000
rs75603868 lBF = 15.5379   Chr19 : 8,063,275
0.437 0.563 0.000
rs185543003 lBF = 13.0544   Chr19 : 2,714,170
0.436 0.563 0.000
rs58542926 lBF = 25.9472   Chr19 : 19,379,549
0.434 0.566 0.000
rs36097565 lBF = 19.5629   Chr19 : 11,461,486
0.434 0.566 0.000
rs4252548 lBF = 18.3224   Chr19 : 55,879,672
0.434 0.566 0.000
rs78655842 lBF = 17.3062   Chr19 : 40,421,859
0.432 0.567 0.000
rs113294279 lBF = 8.41477   Chr19 : 23,089,268
0.431 0.569 0.000
rs72999033 lBF = 13.7459   Chr19 : 19,366,632
0.430 0.570 0.000
rs79462828 lBF = 12.037   Chr19 : 58,433,440
0.430 0.570 0.000
rs34640515 lBF = 10.3518   Chr19 : 58,401,317
0.429 0.571 0.000
rs12972378 lBF = 13.8299   Chr19 : 5,649,716
0.429 0.571 0.000
rs11880316 lBF = 2.78694   Chr19 : 31,911,129
0.428 0.572 0.000
rs8102150 lBF = 1.24544   Chr19 : 50,230,327
0.424 0.575 0.000
rs118009375 lBF = 15.4206   Chr19 : 51,406,426
0.423 0.577 0.000
rs76734869 lBF = 7.03241   Chr19 : 4,723,273
0.418 0.581 0.000
rs115881343 lBF = 21.7731   Chr19 : 45,403,216
0.416 0.584 0.000
rs150268548 lBF = 12.0978   Chr19 : 19,494,483
0.416 0.584 0.000
rs139256956 lBF = 2.77402   Chr19 : 31,097,322
0.415 0.585 0.000
rs149546760 lBF = 2.65423   Chr19 : 56,091,332
0.410 0.590 0.000
rs80008812 lBF = 14.3141   Chr19 : 53,500,544
0.409 0.590 0.000
rs78168814 lBF = 14.9865   Chr19 : 440,655
0.409 0.591 0.000
rs117549422 lBF = 15.8527   Chr19 : 3,415,481
0.407 0.593 0.000
rs62109865 lBF = 0.999309   Chr19 : 13,037,734
0.405 0.595 0.000
rs922443 lBF = 15.2262   Chr19 : 13,158,643
0.404 0.596 0.000
rs113123495 lBF = 7.90763   Chr19 : 5,587,540
0.404 0.596 0.000
rs8107169 lBF = 12.2513   Chr19 : 22,915,253
0.402 0.598 0.000
rs9677004 lBF = 7.78293   Chr19 : 58,117,083
0.402 0.598 0.000
rs11542187 lBF = 16.6935   Chr19 : 7,992,976
0.397 0.603 0.000
rs112768362 lBF = 13.2418   Chr19 : 1,339,429
0.396 0.603 0.000
rs73918213 lBF = 16.0519   Chr19 : 897,171
0.395 0.605 0.000
rs62128682 lBF = 22.6156   Chr19 : 47,978,171
0.394 0.606 0.000
rs148273964 lBF = 14.1607   Chr19 : 11,433,931
0.394 0.606 0.000
rs10404732 lBF = 11.9177   Chr19 : 22,809,599
0.394 0.606 0.000
rs8102280 lBF = 30.7378   Chr19 : 19,455,750
0.393 0.606 0.000
rs57263982 lBF = 13.1493   Chr19 : 18,726,211
0.393 0.607 0.000
rs78669630 lBF = 18.7344   Chr19 : 57,315,995
0.391 0.609 0.000
rs2228603 lBF = 12.1741   Chr19 : 19,329,924
0.390 0.610 0.000
rs60164086 lBF = 8.49074   Chr19 : 19,300,192
0.389 0.611 0.000
rs34282046 lBF = 10.8372   Chr19 : 19,304,899
0.386 0.613 0.000
rs77441939 lBF = 14.762   Chr19 : 13,479,999
0.383 0.617 0.000
rs78958855 lBF = 19.2036   Chr19 : 33,988,381
0.380 0.620 0.000
rs112962238 lBF = 25.5035   Chr19 : 35,020,567
0.380 0.620 0.000
rs77080457 lBF = 19.9364   Chr19 : 11,490,703
0.373 0.627 0.000
rs78614307 lBF = 12.2775   Chr19 : 5,790,540
0.371 0.628 0.000
rs138451097 lBF = 4.82435   Chr19 : 2,873,629
0.371 0.629 0.000
rs61740110 lBF = 13.1325   Chr19 : 22,942,335
0.369 0.631 0.000
rs147859257 lBF = 4.30735   Chr19 : 6,718,146
0.369 0.631 0.000
rs12459943 lBF = 3.97847   Chr19 : 10,859,508
0.369 0.631 0.000
rs12986171 lBF = 19.4786   Chr19 : 10,773,564
0.369 0.631 0.000
rs139704751 lBF = 3.32066   Chr19 : 55,735,478
0.368 0.631 0.000
rs17242346 lBF = 9.05282   Chr19 : 11,198,780
0.367 0.633 0.000
rs12460850 lBF = 7.93312   Chr19 : 4,742,238
0.358 0.641 0.000
rs2075650 lBF = 139.935   Chr19 : 45,395,619
0.354 0.646 0.000
rs2071699 lBF = 1.60872   Chr19 : 49,254,504
0.353 0.647 0.000
rs73537455 lBF = 15.0818   Chr19 : 19,299,431
0.352 0.648 0.000
rs116954357 lBF = 6.54721   Chr19 : 20,223,681
0.314 0.685 0.001
rs111527185 lBF = 5.658   Chr19 : 673,105
0.312 0.687 0.001
rs182323560 lBF = 0.696792   Chr19 : 37,263,238
0.293 0.706 0.000
rs140900046 lBF = 0.434575   Chr19 : 56,111,075
0.258 0.742 0.000
rs73009507 lBF = 20.7347   Chr19 : 10,961,024
0.239 0.761 0.000
rs6603109 lBF = 0.451115   Chr19 : 7,424,528
0.236 0.764 0.000
rs769449 lBF = 166.029   Chr19 : 45,410,002
0.195 0.805 0.000
rs429358 lBF = 222.835   Chr19 : 45,411,941
0.167 0.833 0.000
rs6857 lBF = 185.788   Chr19 : 45,392,254
0.163 0.836 0.000
rs12976411 lBF = 0.225562   Chr19 : 32,882,020
0.140 0.860 0.000
rs2159128 lBF = 0.223496   Chr19 : 950,380
0.139 0.861 0.000
rs13343954 lBF = 1.72027   Chr19 : 33,527,888
0.129 0.871 0.000
rs4420638 lBF = 199.322   Chr19 : 45,422,946
0.122 0.878 0.000
rs2569559 lBF = 8.14733   Chr19 : 11,214,533
0.117 0.883 0.000
rs116843064 lBF = 18.2988   Chr19 : 8,429,323
0.000 0.884 0.115
rs80050017 lBF = 0.238972   Chr19 : 51,383,200
0.115 0.885 0.000
rs56131196 lBF = 198.195   Chr19 : 45,422,846
0.101 0.899 0.000
rs12721109 lBF = 26.2199   Chr19 : 45,447,221
0.099 0.901 0.000
rs62117160 lBF = 18.2881   Chr19 : 45,232,161
0.099 0.901 0.000
rs59007384 lBF = 103.247   Chr19 : 45,396,665
0.092 0.907 0.000
rs157582 lBF = 98.5206   Chr19 : 45,396,219
0.091 0.909 0.000
rs157581 lBF = 96.9021   Chr19 : 45,395,714
0.085 0.915 0.000
rs632111 lBF = 20.7605   Chr19 : 49,208,978
0.085 0.915 0.000
rs1543922 lBF = 0.0774098   Chr19 : 52,084,836
0.057 0.943 0.000
rs8109288 lBF = 0.0970856   Chr19 : 16,185,559
0.045 0.954 0.000
rs34725611 lBF = 1.29016   Chr19 : 10,477,067
0.045 0.955 0.000
rs34328549 lBF = 11.7329   Chr19 : 7,253,184
0.036 0.963 0.001
rs35967093 lBF = 0.048939   Chr19 : 4,883,741
0.034 0.966 0.000
rs12460587 lBF = 0.0144181   Chr19 : 52,586,919
0.033 0.967 0.000
rs2304256 lBF = 1.51359   Chr19 : 10,475,652
0.033 0.967 0.000
rs10500264 lBF = 0.080598   Chr19 : 33,750,314
0.026 0.974 0.000
rs7255066 lBF = -0.0503042   Chr19 : 45,146,103
0.022 0.978 0.000
rs35106244 lBF = 16.1424   Chr19 : 49,203,829
0.019 0.980 0.000
rs183353539 lBF = -0.0422568   Chr19 : 6,992,244
0.019 0.981 0.000
rs76137255 lBF = 0.0428155   Chr19 : 40,783,832
0.018 0.981 0.000
rs260461 lBF = -0.0143722   Chr19 : 58,770,883
0.018 0.982 0.000
rs10410232 lBF = 0.582788   Chr19 : 33,613,708
0.018 0.982 0.000
rs10416265 lBF = 2.36744   Chr19 : 33,605,300
0.015 0.984 0.000
rs10414689 lBF = 0.00965162   Chr19 : 51,796,299
0.014 0.986 0.000
rs12984174 lBF = -0.0292608   Chr19 : 18,132,540
0.013 0.986 0.000
rs4247374 lBF = 8.59285   Chr19 : 7,252,756
0.012 0.987 0.001
rs8113263 lBF = 0.136126   Chr19 : 13,179,662
0.012 0.988 0.000
rs73039434 lBF = 2.24288   Chr19 : 33,524,919
0.011 0.988 0.000
rs10416218 lBF = 2.47638   Chr19 : 33,599,127
0.011 0.989 0.000
rs1126510 lBF = -0.0566693   Chr19 : 47,123,783
0.010 0.989 0.000
rs73030953 lBF = 0.043773   Chr19 : 38,975,449
0.010 0.989 0.000
rs254262 lBF = -0.0418109   Chr19 : 54,612,628
0.010 0.990 0.000
rs113393842 lBF = 0.0194966   Chr19 : 37,006,567
0.010 0.990 0.000
rs6508941 lBF = 0.664334   Chr19 : 41,015,965
0.009 0.990 0.000
rs931608 lBF = 0.00097034   Chr19 : 22,614,122
0.000 0.991 0.009
rs394819 lBF = 0.00969754   Chr19 : 45,404,579
0.008 0.991 0.000
rs380743 lBF = 13.0683   Chr19 : 49,241,014
0.008 0.992 0.000
rs11673344 lBF = 0.979588   Chr19 : 37,684,966
0.007 0.993 0.000
rs10404342 lBF = -0.0433505   Chr19 : 57,132,238
0.007 0.993 0.000
rs2228671 lBF = 38.6156   Chr19 : 11,210,912
0.006 0.993 0.000
rs1353531 lBF = -0.0319868   Chr19 : 31,846,907
0.006 0.994 0.000
rs7507204 lBF = -0.0354556   Chr19 : 3,428,834
0.006 0.994 0.000
rs7249887 lBF = -0.0333678   Chr19 : 31,849,368
0.005 0.994 0.000
rs73931391 lBF = 0.0470993   Chr19 : 41,407,874
0.005 0.995 0.000
rs1551570 lBF = -0.0615668   Chr19 : 10,218,030
0.005 0.995 0.000
rs874628 lBF = -0.0124927   Chr19 : 18,304,700
0.004 0.996 0.000
rs116520962 lBF = 0.00482261   Chr19 : 51,398,427
0.004 0.996 0.000
rs1354774 lBF = 0.514863   Chr19 : 51,393,118
0.004 0.996 0.000
rs7253430 lBF = -0.101165   Chr19 : 1,803,582
0.004 0.996 0.000
rs4528684 lBF = 0.0522251   Chr19 : 14,351,574
0.004 0.996 0.000
rs11666341 lBF = -0.038444   Chr19 : 52,601,399
0.004 0.996 0.000
rs11085727 lBF = 1.40057   Chr19 : 10,466,123
0.004 0.996 0.000
rs72974768 lBF = 0.467852   Chr19 : 3,435,545
0.004 0.996 0.000
rs11878732 lBF = -0.0329447   Chr19 : 31,828,848
0.004 0.996 0.000
rs10411428 lBF = -0.0487839   Chr19 : 52,607,765
0.004 0.996 0.000
rs16964543 lBF = 0.0583383   Chr19 : 31,185,210
0.003 0.996 0.001
rs17692336 lBF = 6.65834   Chr19 : 32,972,119
0.000 0.997 0.003
rs8100241 lBF = 0.0778512   Chr19 : 17,392,894
0.003 0.997 0.000
rs12982744 lBF = 0.297028   Chr19 : 2,177,193
0.003 0.997 0.000
rs3892630 lBF = -0.0340664   Chr19 : 33,181,484
0.003 0.997 0.000
rs3815700 lBF = -0.0233894   Chr19 : 33,093,252
0.003 0.997 0.000
rs4142248 lBF = 0.0155676   Chr19 : 44,888,276
0.003 0.997 0.000
rs4804416 lBF = 2.77307   Chr19 : 7,223,848
0.003 0.997 0.000
rs17356664 lBF = 0.684789   Chr19 : 45,740,771
0.003 0.997 0.000
rs34536443 lBF = 10.435   Chr19 : 10,463,118
0.001 0.997 0.002
rs67731056 lBF = 8.73421   Chr19 : 7,264,549
0.002 0.997 0.001
rs11880992 lBF = 0.471001   Chr19 : 2,176,403
0.003 0.997 0.000
rs1077667 lBF = -0.0556839   Chr19 : 6,668,972
0.003 0.997 0.000
rs2363956 lBF = 0.0988604   Chr19 : 17,394,124
0.002 0.997 0.000
rs2230199 lBF = 0.00787425   Chr19 : 6,718,387
0.003 0.997 0.000
rs10425465 lBF = 0.0343679   Chr19 : 33,897,934
0.003 0.997 0.000
rs2115386 lBF = -0.0851218   Chr19 : 7,196,565
0.000 0.997 0.002
rs3786800 lBF = -0.0668199   Chr19 : 30,990,700
0.000 0.997 0.002
rs11668477 lBF = 39.7389   Chr19 : 11,195,030
0.002 0.997 0.000
rs4808260 lBF = 0.0927022   Chr19 : 20,846,271
0.002 0.997 0.001
rs8101609 lBF = 7.44519   Chr19 : 17,857,482
0.002 0.997 0.000
rs2965260 lBF = -0.0627948   Chr19 : 53,780,026
0.002 0.997 0.000
rs10405693 lBF = 6.62801   Chr19 : 45,326,664
0.002 0.997 0.000
rs732505 lBF = 0.100781   Chr19 : 5,582,535
0.002 0.998 0.000
rs2967605 lBF = 0.661749   Chr19 : 8,469,738
0.002 0.998 0.000
rs6511721 lBF = 11.4118   Chr19 : 11,206,575
0.000 0.998 0.002
rs2279008 lBF = -0.0806357   Chr19 : 17,283,303
0.002 0.998 0.000
rs2288884 lBF = 0.098259   Chr19 : 52,532,271
0.002 0.998 0.000
rs56289821 lBF = 77.2625   Chr19 : 11,188,247
0.002 0.998 0.000
rs270776 lBF = -0.0753872   Chr19 : 55,222,807
0.002 0.998 0.000
rs1434579 lBF = -0.0763562   Chr19 : 44,932,972
0.002 0.998 0.000
rs73592448 lBF = 7.09386   Chr19 : 36,258,721
0.001 0.998 0.001
rs11083846 lBF = -0.0278177   Chr19 : 47,207,654
0.002 0.998 0.000
Affx-15892044 lBF = 7.1836   Chr19 : 36,230,767
0.001 0.998 0.001
rs17694108 lBF = 1.03939   Chr19 : 33,731,551
0.002 0.998 0.000
rs117276938 lBF = -0.0121093   Chr19 : 49,576,802
0.002 0.998 0.000
rs2280401 lBF = 0.0332437   Chr19 : 50,000,009
0.002 0.998 0.000
rs142130958 lBF = 78.6315   Chr19 : 11,190,652
0.002 0.998 0.000
rs112374545 lBF = 78.2181   Chr19 : 11,188,899
0.002 0.998 0.000
rs146861169 lBF = 0.00120274   Chr19 : 7,792,243
0.001 0.998 0.000
rs11083840 lBF = -0.0115573   Chr19 : 47,119,910
0.002 0.998 0.000
rs55791371 lBF = 78.5581   Chr19 : 11,188,153
0.002 0.998 0.000
rs57549656 lBF = 0.0124631   Chr19 : 2,687,651
0.002 0.998 0.000
rs16975963 lBF = -0.0407691   Chr19 : 38,325,536
0.002 0.998 0.000
rs1160985 lBF = 12.3497   Chr19 : 45,403,412
0.002 0.998 0.000
rs7246967 lBF = 0.367199   Chr19 : 23,056,346
0.002 0.998 0.000
rs11671104 lBF = -0.0398445   Chr19 : 22,794,686
0.002 0.998 0.000
rs6511720 lBF = 79.2472   Chr19 : 11,202,306
0.002 0.998 0.000
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0.000 0.999 0.000
rs17699030 lBF = -0.025464   Chr19 : 11,330,942
0.000 0.999 0.000
rs12972990 lBF = -0.0273081   Chr19 : 10,406,431
0.000 0.999 0.000
rs263063 lBF = -0.0338228   Chr19 : 5,022,604
0.000 0.999 0.000
rs737337 lBF = -0.0405924   Chr19 : 11,347,493
0.000 0.999 0.000
rs2287921 lBF = 22.4626   Chr19 : 49,228,272
0.000 0.999 0.000
rs7253117 lBF = 8.58485   Chr19 : 17,844,894
0.001 0.999 0.000
rs2075710 lBF = 6.70349   Chr19 : 1,106,845
0.001 0.999 0.000
rs11084753 lBF = 0.62437   Chr19 : 34,322,137
0.001 0.999 0.000
rs6509942 lBF = 0.344033   Chr19 : 30,554,951
0.000 0.999 0.000
rs3826782 lBF = 0.2238   Chr19 : 6,887,736
0.000 0.999 0.000
rs3745516 lBF = 0.185966   Chr19 : 50,926,742
0.001 0.999 0.000
rs17692896 lBF = 0.00749583   Chr19 : 33,089,431
0.000 0.999 0.000
rs140520053 lBF = -0.00095297   Chr19 : 42,303,947
0.000 0.999 0.000
rs3826795 lBF = -0.0156973   Chr19 : 46,800,433
0.000 0.999 0.000
rs4806846 lBF = -0.0182096   Chr19 : 2,410,484
0.000 0.999 0.000
rs7248888 lBF = -0.0234267   Chr19 : 46,974,003
0.000 0.999 0.000
rs2014572 lBF = -0.0262769   Chr19 : 57,760,018
0.000 0.999 0.000
rs2278426 lBF = -0.0285551   Chr19 : 11,350,488
0.000 0.999 0.000
rs56873913 lBF = -0.055002   Chr19 : 50,091,199
0.001 0.999 0.000
rs891088 lBF = -0.0961251   Chr19 : 7,184,762
0.000 0.999 0.000
rs12052058 lBF = 10.6082   Chr19 : 11,159,525
0.000 0.999 0.000
rs1122608 lBF = 10.0379   Chr19 : 11,163,601
0.000 0.999 0.000
rs139806220 lBF = 1.3495   Chr19 : 55,161,522
0.000 0.999 0.000
rs16966122 lBF = 0.219204   Chr19 : 32,158,464
0.000 0.999 0.000
rs8105429 lBF = 0.113411   Chr19 : 18,481,333
0.001 0.999 0.000
rs3764618 lBF = 0.106329   Chr19 : 49,497,155
0.000 0.999 0.000
rs117492019 lBF = 0.0160085   Chr19 : 58,681,861
0.000 0.999 0.000
rs10412199 lBF = -0.00347688   Chr19 : 3,927,771
0.000 0.999 0.000
rs740406 lBF = -0.0227422   Chr19 : 2,232,221
0.000 0.999 0.000
rs28493229 lBF = -0.0547884   Chr19 : 41,224,204
0.000 0.999 0.000
rs35976034 lBF = 9.67348   Chr19 : 17,832,748
0.000 0.999 0.000
rs7339483 lBF = 0.468308   Chr19 : 24,462,409
0.000 0.999 0.000
rs10409958 lBF = 0.020407   Chr19 : 46,953,382
0.000 0.999 0.000
rs1382358 lBF = 0.010017   Chr19 : 13,171,424
0.000 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.2879
Cluster X0333
log Bayes Factor = 38.671
contains 2 variants
0.2410
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.9954
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.9936
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.9913
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.9739
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.9658
Cluster X0035
log Bayes Factor = 620.567
contains 37 variants
0.9635
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.9607
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.9597
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.9593
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.9533
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.9532
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.9525
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.9479
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.9251
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.9243
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.9233
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.9140
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.9056
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.9053
Cluster X0219
log Bayes Factor = 230.324
contains 15 variants
0.9031
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.9008
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.9007
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.8992
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.8941
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.8915
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.8886
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.8836
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.8812
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.8769
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.8745
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.8685
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.8684
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.8654
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.8569
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.8565
Cluster X0196
log Bayes Factor = 301.726
contains 18 variants
0.8518
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.8474
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.8467
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.8377
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.8333
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.8281
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.8271
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.8185
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.8181
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.8023
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.8013
Cluster X0125
log Bayes Factor = 215.738
contains 7 variants
0.8009
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.7997
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.7940
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.7879
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.7823
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.7803
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.7789
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.7787
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.7749
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.7716
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.7675
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.7656
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.7630
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.7586
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.7531
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.7487
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.7446
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.7432
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.7425
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.7420
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.7411
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.7353
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.7321
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.7319
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.7290
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.7178
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.7123
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.7106
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.7084
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.7073
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.7069
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.7051
Cluster X0147
log Bayes Factor = 133.509
contains 9 variants
0.7028
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.7024
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.6990
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.6868
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.6776
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.6756
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.6749
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.6747
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.6726
Cluster X0127
log Bayes Factor = 276.004
contains 14 variants
0.6726
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.6722
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.6694
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.6691
Cluster X0315
log Bayes Factor = 42.686
contains 2 variants
0.6658
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.6643
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.6588
Cluster X0223
log Bayes Factor = 122.347
contains 7 variants
0.6584
Cluster X0267
log Bayes Factor = 92.4806
contains 5 variants
0.6562
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.6495
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.6462
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.6438
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.6411
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.6363
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.6325
Cluster X0244
log Bayes Factor = 122.647
contains 5 variants
0.6292
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.6275
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.6263
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.6262
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.6247
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.6238
Cluster X0062
log Bayes Factor = 68.7461
contains 4 variants
0.6213
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.6187
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.6186
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.6179
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.6137
Cluster X0245
log Bayes Factor = 256.009
contains 7 variants
0.6070
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.6069
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.6052
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.6026
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.6004
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.5976
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.5975
Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.5951
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.5949
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.5921
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.5901
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.5888
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.5884
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.5881
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.5867
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.5864
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.5846
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.5787
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.5774
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.5773
Cluster X0225
log Bayes Factor = 36.4143
contains 3 variants
0.5750
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.5729
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.5699
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.5698
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.5693
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.5641
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.5624
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.5623
Cluster X0065
log Bayes Factor = 53.0717
contains 3 variants
0.5583
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.5570
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.5545
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.5509
Cluster X0273
log Bayes Factor = 109.896
contains 6 variants
0.5490
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.5478
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.5475
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.5459
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.5400
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.5393
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.5393
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.5294
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.5291
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.5285
Cluster X0269
log Bayes Factor = 155.455
contains 9 variants
0.5276
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.5272
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.5260
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.5215
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.5202
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.5180
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.5170
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.5127
Cluster X0247
log Bayes Factor = 98.6507
contains 6 variants
0.5118
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.5117
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.5112
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.5110
Cluster X0270
log Bayes Factor = 41.2082
contains 4 variants
0.5101
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.5097
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.5082
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.5075
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.5037
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.5028
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.4992
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.4943
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.4906
Cluster X0002
log Bayes Factor = 522.044
contains 22 variants
0.4846
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.4780
Cluster X0230
log Bayes Factor = 131.696
contains 7 variants
0.4765
Cluster X0128
log Bayes Factor = 148.918
contains 15 variants
0.4761
Cluster X0266
log Bayes Factor = 95.1792
contains 5 variants
0.4703
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.4580
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.4569
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.4569
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.4512
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.4500
Cluster X0193
log Bayes Factor = 303.265
contains 16 variants
0.4493
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.4427
Cluster X0103
log Bayes Factor = 194.456
contains 13 variants
0.4331
Cluster X0278
log Bayes Factor = 173.437
contains 11 variants
0.4271
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.4249
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.4235
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.4182
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.4128
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.4087
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.4021
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.4013
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.3987
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.3982
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.3919
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.3893
Cluster X0301
log Bayes Factor = 297.489
contains 2 variants
0.3883
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.3882
Cluster X0328
log Bayes Factor = 380.087
contains 8 variants
0.3868
Cluster X0234
log Bayes Factor = 28.8983
contains 2 variants
0.3863
Cluster X0199
log Bayes Factor = 350.038
contains 3 variants
0.3847
Cluster X0173
log Bayes Factor = 654.164
contains 9 variants
0.3806
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.3676
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.3675
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.3669
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.3665
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.3613
Cluster X0300
log Bayes Factor = 109.684
contains 3 variants
0.3551
Cluster X0113
log Bayes Factor = 49.7598
contains 3 variants
0.3524
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.3460
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.3255
Cluster X0195
log Bayes Factor = 167.337
contains 13 variants
0.3237
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.3209
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.3208
Cluster X0004
log Bayes Factor = 32.8452
contains 2 variants
0.3146
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.3122
Cluster X0279
log Bayes Factor = 52.8832
contains 2 variants
0.3099
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.3085
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.3031
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.3006
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.2990
Cluster X0179
log Bayes Factor = 426.274
contains 17 variants
0.2950
Cluster X0160
log Bayes Factor = 99.5328
contains 9 variants
0.2941
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.2910
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.2628
Cluster X0172
log Bayes Factor = 80.2701
contains 3 variants
0.2524
Cluster X0206
log Bayes Factor = 56.4479
contains 3 variants
0.2121
Cluster X0324
log Bayes Factor = 32.1341
contains 1 variants
0.1917
Cluster X0136
log Bayes Factor = 105.47
contains 5 variants
0.1185
Cluster X0298
log Bayes Factor = 220.671
contains 1 variants
0.0640
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.0546
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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