TreeWAS – [Z89.6] Acquired absence of leg above knee

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs215398 lBF = `19.4313` Chr`12` : `47,767,134`	0.611	0.389	0.000
rs79918060 lBF = `17.5524` Chr`12` : `58,407,669`	0.605	0.395	0.000
rs116877397 lBF = `30.7668` Chr`12` : `121,162,996`	0.601	0.399	0.000
rs61756485 lBF = `16.787` Chr`12` : `99,020,125`	0.592	0.408	0.000
rs117091826 lBF = `24.5799` Chr`12` : `112,629,713`	0.586	0.414	0.000
rs73045775 lBF = `23.3857` Chr`12` : `8,674,905`	0.583	0.417	0.000
rs41279092 lBF = `7.635` Chr`12` : `112,924,706`	0.000	0.419	0.581
rs11059555 lBF = `14.4188` Chr`12` : `128,646,039`	0.580	0.420	0.000
rs12813285 lBF = `22.3499` Chr`12` : `68,206,219`	0.572	0.428	0.000
rs117089640 lBF = `23.0292` Chr`12` : `125,048,557`	0.571	0.428	0.000
rs73141422 lBF = `22.399` Chr`12` : `83,882,469`	0.571	0.428	0.000
rs61944384 lBF = `10.148` Chr`12` : `111,952,215`	0.000	0.430	0.570
rs117636037 lBF = `18.8537` Chr`12` : `38,519,375`	0.560	0.440	0.000
rs11108227 lBF = `16.4201` Chr`12` : `96,134,001`	0.560	0.440	0.000
rs12321507 lBF = `16.2879` Chr`12` : `96,134,818`	0.558	0.442	0.000
rs117929870 lBF = `16.9839` Chr`12` : `108,524,849`	0.553	0.447	0.000
Affx-8411664 lBF = `18.4862` Chr`12` : `71,094,955`	0.553	0.447	0.000
rs144700679 lBF = `7.09223` Chr`12` : `115,468,959`	0.550	0.450	0.000
rs118113273 lBF = `22.5923` Chr`12` : `128,300,100`	0.549	0.451	0.000
rs12423747 lBF = `15.1947` Chr`12` : `71,084,299`	0.543	0.457	0.000
rs112742247 lBF = `13.3959` Chr`12` : `85,030,619`	0.533	0.466	0.000
rs76001134 lBF = `19.3411` Chr`12` : `23,209,903`	0.528	0.472	0.000
rs78221103 lBF = `16.6479` Chr`12` : `104,562,673`	0.528	0.472	0.000
rs117437287 lBF = `16.5299` Chr`12` : `23,389,839`	0.527	0.473	0.000
rs75489010 lBF = `27.7624` Chr`12` : `115,986,702`	0.518	0.482	0.000
rs7298767 lBF = `17.6072` Chr`12` : `22,475,701`	0.514	0.486	0.000
rs12582852 lBF = `14.3759` Chr`12` : `3,315,933`	0.514	0.486	0.000
rs114453043 lBF = `22.0948` Chr`12` : `25,461,756`	0.514	0.486	0.000
rs76796201 lBF = `14.1948` Chr`12` : `23,091,755`	0.514	0.486	0.000
rs35729753 lBF = `17.3029` Chr`12` : `66,672,379`	0.514	0.486	0.000
rs34574480 lBF = `13.3586` Chr`12` : `115,307,567`	0.513	0.487	0.000
rs117139804 lBF = `18.4888` Chr`12` : `116,233,671`	0.513	0.487	0.000
rs75289085 lBF = `19.4964` Chr`12` : `18,147,653`	0.513	0.487	0.000
rs80160299 lBF = `15.0308` Chr`12` : `66,159,224`	0.512	0.488	0.000
rs77649004 lBF = `14.247` Chr`12` : `96,135,916`	0.502	0.497	0.000
rs117802803 lBF = `21.4181` Chr`12` : `22,796,804`	0.491	0.509	0.000
rs182057829 lBF = `2.49683` Chr`12` : `97,412,327`	0.476	0.524	0.000
rs3809128 lBF = `2.10909` Chr`12` : `56,709,919`	0.464	0.536	0.000
rs17102257 lBF = `14.6206` Chr`12` : `54,126,061`	0.460	0.540	0.000
rs1653608 lBF = `16.5227` Chr`12` : `121,706,733`	0.436	0.564	0.000
rs2279695 lBF = `6.13321` Chr`12` : `117,154,262`	0.429	0.571	0.000
rs2417373 lBF = `14.5305` Chr`12` : `14,744,468`	0.412	0.588	0.000
rs118009632 lBF = `0.732821` Chr`12` : `54,959,672`	0.000	0.592	0.408
rs188610 lBF = `2.31323` Chr`12` : `313,839`	0.398	0.601	0.000
rs117759274 lBF = `14.7453` Chr`12` : `23,131,855`	0.390	0.609	0.000
rs6580622 lBF = `15.5075` Chr`12` : `47,936,778`	0.386	0.614	0.000
rs187986843 lBF = `15.061` Chr`12` : `69,080,770`	0.377	0.623	0.000
rs117629949 lBF = `14.77` Chr`12` : `25,021,224`	0.376	0.624	0.000
rs78437391 lBF = `22.4064` Chr`12` : `129,229,615`	0.360	0.640	0.000
rs192051543 lBF = `14.1247` Chr`12` : `22,657,770`	0.357	0.642	0.000
rs79015790 lBF = `14.8688` Chr`12` : `128,700,249`	0.352	0.647	0.000
rs704080 lBF = `11.6648` Chr`12` : `89,749,223`	0.351	0.649	0.000
rs117458579 lBF = `15.4218` Chr`12` : `15,351,989`	0.280	0.720	0.000
rs73164250 lBF = `17.0593` Chr`12` : `84,624,334`	0.279	0.720	0.000
rs73217910 lBF = `14.853` Chr`12` : `118,450,865`	0.267	0.733	0.000
rs187353341 lBF = `19.0434` Chr`12` : `121,557,376`	0.256	0.744	0.000
rs117557466 lBF = `12.1727` Chr`12` : `69,802,569`	0.230	0.770	0.000
rs35446494 lBF = `7.95755` Chr`12` : `119,533,218`	0.226	0.773	0.000
rs1528287 lBF = `13.6349` Chr`12` : `80,985,872`	0.223	0.777	0.000
rs117761474 lBF = `15.8826` Chr`12` : `113,029,356`	0.201	0.799	0.000
rs10506821 lBF = `13.2804` Chr`12` : `80,496,923`	0.189	0.810	0.000
rs74910874 lBF = `2.61067` Chr`12` : `67,086,810`	0.177	0.822	0.000
rs117605016 lBF = `28.0976` Chr`12` : `129,614,385`	0.169	0.831	0.000
rs9332958 lBF = `5.25634` Chr`12` : `16,519,263`	0.163	0.836	0.000
rs78294386 lBF = `14.58` Chr`12` : `107,963,652`	0.158	0.841	0.000
rs1235153 lBF = `9.04692` Chr`12` : `48,110,325`	0.155	0.845	0.000
rs75311705 lBF = `0.456159` Chr`12` : `125,714,596`	0.137	0.863	0.000
rs77103806 lBF = `6.36663` Chr`12` : `23,021,423`	0.130	0.870	0.000
rs76409154 lBF = `20.1612` Chr`12` : `85,692,134`	0.129	0.870	0.000
rs12425131 lBF = `16.2355` Chr`12` : `82,984,879`	0.125	0.875	0.000
rs144288546 lBF = `0.146461` Chr`12` : `129,069,682`	0.111	0.889	0.000
rs2608700 lBF = `16.0704` Chr`12` : `41,884,414`	0.107	0.893	0.000
rs74911677 lBF = `20.5271` Chr`12` : `122,015,993`	0.105	0.895	0.000
rs116938548 lBF = `0.178688` Chr`12` : `4,808,251`	0.099	0.901	0.000
rs3184504 lBF = `147.788` Chr`12` : `111,884,608`	0.093	0.907	0.000
rs17040357 lBF = `13.7026` Chr`12` : `108,665,316`	0.092	0.907	0.000
rs10774624 lBF = `108.174` Chr`12` : `111,833,788`	0.000	0.914	0.086
rs181609621 lBF = `1.56948` Chr`12` : `32,810,759`	0.078	0.922	0.000
rs11609031 lBF = `16.3836` Chr`12` : `99,307,725`	0.071	0.928	0.000
rs76450399 lBF = `14.1937` Chr`12` : `9,143,781`	0.071	0.928	0.000
rs11608709 lBF = `15.4681` Chr`12` : `99,302,859`	0.071	0.929	0.000
rs77821460 lBF = `20.1742` Chr`12` : `20,274,936`	0.061	0.938	0.000
rs7310615 lBF = `134.377` Chr`12` : `111,865,049`	0.000	0.939	0.061
rs56269309 lBF = `12.8645` Chr`12` : `127,453,025`	0.061	0.939	0.000
rs16906714 lBF = `0.0571485` Chr`12` : `30,860,557`	0.058	0.942	0.000
rs10774625 lBF = `134.733` Chr`12` : `111,910,219`	0.058	0.942	0.000
rs11175593 lBF = `2.45774` Chr`12` : `40,601,940`	0.057	0.943	0.000
rs4766578 lBF = `133.156` Chr`12` : `111,904,371`	0.000	0.947	0.053
rs76242156 lBF = `19.5711` Chr`12` : `65,043,774`	0.053	0.947	0.000
rs7137828 lBF = `136.212` Chr`12` : `111,932,800`	0.000	0.951	0.049
rs115720202 lBF = `18.7627` Chr`12` : `89,746,581`	0.043	0.957	0.000
rs35587409 lBF = `12.2827` Chr`12` : `100,841,306`	0.041	0.959	0.000
rs117409850 lBF = `13.4266` Chr`12` : `106,057,582`	0.040	0.960	0.000
rs79476482 lBF = `14.9329` Chr`12` : `76,084,550`	0.039	0.961	0.000
rs11115322 lBF = `13.8059` Chr`12` : `83,019,188`	0.036	0.963	0.000
rs61943445 lBF = `13.7019` Chr`12` : `118,861,521`	0.036	0.964	0.000
rs597808 lBF = `138.181` Chr`12` : `111,973,358`	0.000	0.967	0.033
rs79002142 lBF = `11.7979` Chr`12` : `85,143,591`	0.032	0.968	0.000
rs12582659 lBF = `4.82974` Chr`12` : `76,064,528`	0.028	0.972	0.000
rs183825572 lBF = `0.0255777` Chr`12` : `101,264,845`	0.027	0.972	0.000
rs11174454 lBF = `8.97302` Chr`12` : `62,781,002`	0.027	0.973	0.000
rs79235855 lBF = `16.45` Chr`12` : `1,537,749`	0.025	0.975	0.000
rs7307123 lBF = `21.9581` Chr`12` : `54,524,397`	0.023	0.977	0.000
rs653178 lBF = `141.209` Chr`12` : `112,007,756`	0.021	0.979	0.000
rs12422544 lBF = `1.68441` Chr`12` : `40,528,432`	0.018	0.981	0.000
rs78321382 lBF = `14.0322` Chr`12` : `17,070,922`	0.018	0.982	0.000
rs188255132 lBF = `0.0230843` Chr`12` : `81,723,188`	0.015	0.985	0.000
rs4594074 lBF = `0.0140546` Chr`12` : `41,032,092`	0.014	0.986	0.000
rs75876943 lBF = `15.0045` Chr`12` : `86,555,845`	0.014	0.986	0.000
rs12371484 lBF = `19.7008` Chr`12` : `111,872,722`	0.014	0.986	0.000
rs12370770 lBF = `24.384` Chr`12` : `112,277,084`	0.013	0.987	0.000
rs7307780 lBF = `0.176028` Chr`12` : `76,220,618`	0.013	0.987	0.000
rs117029533 lBF = `21.9889` Chr`12` : `66,632,067`	0.009	0.991	0.000
rs16914920 lBF = `12.1807` Chr`12` : `19,128,595`	0.009	0.991	0.000
rs117492744 lBF = `13.2788` Chr`12` : `29,747,631`	0.009	0.991	0.000
rs117863495 lBF = `14.7593` Chr`12` : `129,432,374`	0.008	0.992	0.000
rs7973748 lBF = `7.3862` Chr`12` : `20,164,705`	0.008	0.992	0.000
rs17443266 lBF = `15.2354` Chr`12` : `19,169,453`	0.008	0.992	0.000
rs118152513 lBF = `0.00652999` Chr`12` : `101,184,252`	0.000	0.992	0.008
rs117439611 lBF = `14.8831` Chr`12` : `520,944`	0.008	0.992	0.000
rs71454665 lBF = `8.54321` Chr`12` : `121,198,711`	0.008	0.992	0.000
rs12814941 lBF = `12.4883` Chr`12` : `106,408,172`	0.008	0.992	0.000
rs1920592 lBF = `0.100461` Chr`12` : `114,705,586`	0.008	0.992	0.000
rs149104283 lBF = `2.00778` Chr`12` : `21,083,862`	0.007	0.993	0.000
rs16932667 lBF = `-0.0776762` Chr`12` : `5,131,553`	0.000	0.993	0.007
rs4238083 lBF = `14.8083` Chr`12` : `42,924,769`	0.007	0.993	0.000
rs11055612 lBF = `-0.0887438` Chr`12` : `13,923,328`	0.000	0.993	0.007
rs187293782 lBF = `0.0145963` Chr`12` : `76,157,356`	0.006	0.993	0.000
rs2261181 lBF = `5.79392` Chr`12` : `66,212,318`	0.007	0.993	0.000
rs12308914 lBF = `12.8877` Chr`12` : `104,633,842`	0.006	0.993	0.000
rs1043763 lBF = `-0.0415101` Chr`12` : `122,630,909`	0.006	0.994	0.000
rs1531343 lBF = `3.25594` Chr`12` : `66,174,894`	0.006	0.994	0.000
rs2733283 lBF = `17.1055` Chr`12` : `41,935,977`	0.006	0.994	0.000
rs522958 lBF = `-0.0794194` Chr`12` : `28,228,567`	0.006	0.994	0.000
rs2722223 lBF = `24.9818` Chr`12` : `90,233,876`	0.006	0.994	0.000
rs117154046 lBF = `0.0198739` Chr`12` : `29,542,777`	0.005	0.994	0.000
rs11247009 lBF = `-0.0668129` Chr`12` : `132,701,184`	0.000	0.995	0.005
rs55922880 lBF = `0.00435799` Chr`12` : `115,617,641`	0.005	0.995	0.000
rs673078 lBF = `-0.0673754` Chr`12` : `118,791,441`	0.000	0.995	0.005
rs3752728 lBF = `6.24552` Chr`12` : `20,192,972`	0.005	0.995	0.000
rs76191003 lBF = `9.4885` Chr`12` : `47,182,531`	0.005	0.995	0.000
rs183032784 lBF = `0.00474184` Chr`12` : `118,257,214`	0.004	0.995	0.000
rs17126180 lBF = `0.00493889` Chr`12` : `52,263,956`	0.000	0.996	0.004
rs182328274 lBF = `0.0032004` Chr`12` : `107,667,802`	0.004	0.996	0.000
rs73114523 lBF = `14.6366` Chr`12` : `54,602,032`	0.004	0.996	0.000
rs118079879 lBF = `5.09035` Chr`12` : `41,713,306`	0.004	0.996	0.000
rs73040424 lBF = `7.46879` Chr`12` : `5,665,454`	0.004	0.996	0.000
rs59753639 lBF = `4.25806` Chr`12` : `25,140,690`	0.004	0.996	0.000
rs7137521 lBF = `0.00252492` Chr`12` : `126,734,269`	0.004	0.996	0.000
rs12367822 lBF = `-0.0581335` Chr`12` : `57,204,160`	0.004	0.996	0.000
rs10777317 lBF = `-0.0607484` Chr`12` : `91,980,374`	0.000	0.996	0.004
rs76775795 lBF = `13.6666` Chr`12` : `115,385,431`	0.004	0.996	0.000
rs11114027 lBF = `-0.0369385` Chr`12` : `79,775,248`	0.004	0.996	0.000
rs4149639 lBF = `0.234732` Chr`12` : `6,442,001`	0.003	0.996	0.000
rs941184 lBF = `0.00357459` Chr`12` : `54,114,158`	0.003	0.996	0.000
rs2417820 lBF = `7.60635` Chr`12` : `20,190,474`	0.004	0.996	0.000
rs3951439 lBF = `0.0044521` Chr`12` : `51,727,596`	0.000	0.996	0.003
rs12322695 lBF = `0.0399753` Chr`12` : `117,199,414`	0.003	0.997	0.000
rs7314326 lBF = `0.607786` Chr`12` : `24,107,597`	0.003	0.997	0.000
rs183160876 lBF = `0.00279977` Chr`12` : `82,463,439`	0.003	0.997	0.000
rs1040026 lBF = `0.00233431` Chr`12` : `71,210,678`	0.003	0.997	0.000
rs790006 lBF = `-0.0175315` Chr`12` : `64,606,439`	0.003	0.997	0.000
rs7310309 lBF = `-0.042297` Chr`12` : `79,811,429`	0.000	0.997	0.003
rs80132640 lBF = `11.0963` Chr`12` : `49,426,460`	0.003	0.997	0.000
rs10877839 lBF = `-0.0977914` Chr`12` : `62,818,481`	0.003	0.997	0.000
rs12817488 lBF = `0.741885` Chr`12` : `123,296,294`	0.003	0.997	0.000
rs2657880 lBF = `0.0100386` Chr`12` : `56,863,770`	0.000	0.997	0.003
rs1520223 lBF = `0.00239145` Chr`12` : `102,726,338`	0.002	0.997	0.000
rs2638315 lBF = `-0.0199053` Chr`12` : `56,865,056`	0.000	0.997	0.003
rs1386003 lBF = `12.5875` Chr`12` : `13,213,682`	0.002	0.997	0.000
rs34637584 lBF = `0.00195999` Chr`12` : `40,734,202`	0.002	0.997	0.000
rs7309269 lBF = `13.6679` Chr`12` : `7,757,834`	0.002	0.997	0.000
rs80002652 lBF = `18.6612` Chr`12` : `107,437,422`	0.002	0.997	0.000
rs1265564 lBF = `58.6971` Chr`12` : `111,708,458`	0.002	0.997	0.000
rs11044722 lBF = `15.4222` Chr`12` : `19,781,710`	0.002	0.997	0.000
rs11060180 lBF = `0.701454` Chr`12` : `123,303,586`	0.000	0.998	0.002
rs11834041 lBF = `-0.0553571` Chr`12` : `128,234,629`	0.002	0.998	0.000
rs7978895 lBF = `-0.0953489` Chr`12` : `43,570,515`	0.000	0.998	0.002
rs75593565 lBF = `13.6234` Chr`12` : `32,115,266`	0.002	0.998	0.000
rs11047510 lBF = `-0.0931089` Chr`12` : `8,989,916`	0.000	0.998	0.002
rs111969502 lBF = `5.3967` Chr`12` : `59,848,381`	0.002	0.998	0.000
rs10783624 lBF = `-0.0622892` Chr`12` : `39,522,907`	0.000	0.998	0.002
rs2965667 lBF = `-0.019105` Chr`12` : `17,444,733`	0.000	0.998	0.002
rs3847687 lBF = `-0.0574797` Chr`12` : `131,525,053`	0.002	0.998	0.000
rs3217863 lBF = `9.55969` Chr`12` : `4,399,496`	0.002	0.998	0.000
rs73200436 lBF = `2.81861` Chr`12` : `110,062,693`	0.002	0.998	0.000
rs2731620 lBF = `-0.0901159` Chr`12` : `19,927,800`	0.000	0.998	0.002
rs117626015 lBF = `0.00164872` Chr`12` : `41,624,795`	0.002	0.998	0.000
rs2291738 lBF = `-0.104617` Chr`12` : `56,815,281`	0.000	0.998	0.002
rs2657879 lBF = `0.00817662` Chr`12` : `56,865,338`	0.000	0.998	0.002
rs343092 lBF = `6.85645` Chr`12` : `66,250,940`	0.002	0.998	0.000
rs4149018 lBF = `0.00161931` Chr`12` : `21,291,561`	0.002	0.998	0.000
rs1531228 lBF = `-0.0326736` Chr`12` : `13,629,381`	0.002	0.998	0.000
rs11168936 lBF = `0.314265` Chr`12` : `49,645,240`	0.002	0.998	0.000
rs73313995 lBF = `22.0276` Chr`12` : `33,622,807`	0.002	0.998	0.000
rs143136847 lBF = `1.54314` Chr`12` : `82,748,339`	0.002	0.998	0.000
rs7295246 lBF = `-0.0554447` Chr`12` : `43,967,677`	0.000	0.998	0.002
rs76595471 lBF = `13.0273` Chr`12` : `80,228,443`	0.002	0.998	0.000
rs10860757 lBF = `-0.0409974` Chr`12` : `102,020,446`	0.002	0.998	0.000
rs10777165 lBF = `0.765632` Chr`12` : `89,840,865`	0.002	0.998	0.000
rs2731006 lBF = `-0.0616696` Chr`12` : `43,160,825`	0.000	0.998	0.002
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rs77572683 lBF = `7.85519` Chr`12` : `114,261,767`	0.000	0.999	0.000
rs2285810 lBF = `5.79517` Chr`12` : `112,699,540`	0.001	0.999	0.000
rs11059919 lBF = `0.0618` Chr`12` : `129,289,190`	0.001	0.999	0.000
rs10849004 lBF = `-0.0224511` Chr`12` : `4,292,862`	0.000	0.999	0.001
rs4964469 lBF = `-0.0429482` Chr`12` : `106,949,987`	0.001	0.999	0.000
rs12821256 lBF = `-0.0492207` Chr`12` : `89,328,335`	0.001	0.999	0.000
rs1373549 lBF = `-0.05596` Chr`12` : `46,485,838`	0.000	0.999	0.001
rs117470014 lBF = `18.6761` Chr`12` : `74,652,195`	0.001	0.999	0.000
rs10773568 lBF = `-0.12648` Chr`12` : `129,186,190`	0.001	0.999	0.000
rs78549223 lBF = `13.151` Chr`12` : `71,168,008`	0.000	0.999	0.000
rs1169313 lBF = `11.6007` Chr`12` : `121,442,670`	0.001	0.999	0.000
rs4766986 lBF = `8.99695` Chr`12` : `113,076,475`	0.001	0.999	0.000
rs1005902 lBF = `5.81327` Chr`12` : `112,667,675`	0.001	0.999	0.000
rs191780267 lBF = `4.50227` Chr`12` : `89,289,255`	0.000	0.999	0.000
rs5742692 lBF = `2.17819` Chr`12` : `102,799,598`	0.001	0.999	0.000
rs10774610 lBF = `0.180126` Chr`12` : `111,340,243`	0.000	0.999	0.001
rs7312122 lBF = `0.0324516` Chr`12` : `113,158,838`	0.001	0.999	0.000
rs7312770 lBF = `3.19881` Chr`12` : `56,467,587`	0.001	0.999	0.000
rs885389 lBF = `0.0604974` Chr`12` : `131,621,762`	0.001	0.999	0.000
rs2708377 lBF = `0.00974402` Chr`12` : `11,216,315`	0.000	0.999	0.000
rs894734 lBF = `0.00652107` Chr`12` : `54,319,727`	0.001	0.999	0.000
rs6539267 lBF = `-0.0447861` Chr`12` : `106,785,554`	0.001	0.999	0.000
rs7979575 lBF = `-0.0500969` Chr`12` : `24,278,821`	0.000	0.999	0.001
rs57083693 lBF = `-0.0766627` Chr`12` : `101,742,180`	0.001	0.999	0.000
rs789560 lBF = `0.442685` Chr`12` : `70,331,827`	0.001	0.999	0.000
rs11059635 lBF = `0.31419` Chr`12` : `128,782,022`	0.001	0.999	0.000
rs11177669 lBF = `-0.00206854` Chr`12` : `69,828,681`	0.000	0.999	0.000
rs11064768 lBF = `-0.0269596` Chr`12` : `119,818,509`	0.001	0.999	0.000
rs11112046 lBF = `0.314989` Chr`12` : `104,818,192`	0.000	0.999	0.001
rs11113894 lBF = `-0.0231673` Chr`12` : `108,841,863`	0.000	0.999	0.001
rs12230513 lBF = `-0.0367029` Chr`12` : `55,916,780`	0.001	0.999	0.000
rs4148660 lBF = `-0.0495509` Chr`12` : `22,059,617`	0.000	0.999	0.001
rs4883201 lBF = `-0.0580715` Chr`12` : `9,082,581`	0.000	0.999	0.001
rs146238395 lBF = `0.00960375` Chr`12` : `118,443,870`	0.001	0.999	0.000
rs1457614 lBF = `-0.0614078` Chr`12` : `13,641,706`	0.001	0.999	0.000
rs11049611 lBF = `-0.0625499` Chr`12` : `28,600,244`	0.001	0.999	0.000
rs1151008 lBF = `-0.120747` Chr`12` : `32,097,360`	0.000	0.999	0.001
rs11057841 lBF = `14.6163` Chr`12` : `125,316,743`	0.000	0.999	0.000
rs117624816 lBF = `14.1981` Chr`12` : `18,210,143`	0.000	0.999	0.000
rs11171739 lBF = `5.34477` Chr`12` : `56,470,625`	0.001	0.999	0.000
rs7294372 lBF = `0.932637` Chr`12` : `114,637,423`	0.000	0.999	0.000
rs10876993 lBF = `0.280466` Chr`12` : `58,062,667`	0.000	0.999	0.001
rs7304057 lBF = `0.0675331` Chr`12` : `131,352,562`	0.001	0.999	0.000
rs12318506 lBF = `-0.0281108` Chr`12` : `75,718,423`	0.000	0.999	0.001
rs1006737 lBF = `-0.0426692` Chr`12` : `2,345,295`	0.000	0.999	0.001
rs6538140 lBF = `-0.057647` Chr`12` : `77,738,005`	0.000	0.999	0.001
rs11054731 lBF = `-0.0640627` Chr`12` : `12,376,465`	0.001	0.999	0.000
rs7134221 lBF = `-0.0977459` Chr`12` : `97,641,186`	0.000	0.999	0.001
rs10875943 lBF = `0.762503` Chr`12` : `49,676,010`	0.001	0.999	0.000
rs993226 lBF = `0.111824` Chr`12` : `84,886,573`	0.001	0.999	0.000
rs10777845 lBF = `0.0146232` Chr`12` : `97,689,768`	0.000	0.999	0.001
rs12282 lBF = `0.00394501` Chr`12` : `133,345,809`	0.000	0.999	0.000
rs7964004 lBF = `-0.00274793` Chr`12` : `113,132,441`	0.001	0.999	0.000
rs2111902 lBF = `-0.0372365` Chr`12` : `109,278,747`	0.001	0.999	0.000
rs7954567 lBF = `-0.0424768` Chr`12` : `6,491,125`	0.001	0.999	0.000
rs2638953 lBF = `-0.0943266` Chr`12` : `28,534,415`	0.000	0.999	0.001
rs79680354 lBF = `22.0763` Chr`12` : `119,361,070`	0.000	0.999	0.000
rs116962450 lBF = `7.81708` Chr`12` : `90,500,741`	0.000	0.999	0.000
rs11045000 lBF = `7.56762` Chr`12` : `20,184,146`	0.001	0.999	0.000
rs258415 lBF = `1.25111` Chr`12` : `28,017,522`	0.000	0.999	0.001
rs1167125 lBF = `0.204614` Chr`12` : `43,434,282`	0.001	0.999	0.000
rs142494129 lBF = `0.0386533` Chr`12` : `95,161,353`	0.000	0.999	0.000
rs939876 lBF = `0.0093031` Chr`12` : `65,252,118`	0.000	0.999	0.001
rs140785266 lBF = `0.00305033` Chr`12` : `86,195,923`	0.000	0.999	0.000
rs181697701 lBF = `0.00035088` Chr`12` : `107,611,050`	0.000	0.999	0.000
rs17108344 lBF = `-0.00155388` Chr`12` : `70,954,464`	0.000	0.999	0.000
rs7953528 lBF = `1.1414` Chr`12` : `28,017,159`	0.000	0.999	0.001
rs150828104 lBF = `0.860743` Chr`12` : `116,775,695`	0.001	0.999	0.000
rs4981022 lBF = `0.383359` Chr`12` : `104,149,874`	0.001	0.999	0.000
rs73206853 lBF = `0.220246` Chr`12` : `110,708,746`	0.001	0.999	0.000
rs9300212 lBF = `0.0789682` Chr`12` : `33,701,166`	0.000	0.999	0.001
rs4761974 lBF = `0.00489477` Chr`12` : `51,880,445`	0.001	0.999	0.000
rs12321565 lBF = `0.00259808` Chr`12` : `68,532,077`	0.001	0.999	0.000
rs499368 lBF = `-0.00108169` Chr`12` : `320,920`	0.000	0.999	0.000
rs7963521 lBF = `-0.0106444` Chr`12` : `73,828,956`	0.001	0.999	0.000
rs113681054 lBF = `-0.0236609` Chr`12` : `21,402,979`	0.001	0.999	0.000
rs10506621 lBF = `-0.035149` Chr`12` : `71,408,076`	0.001	0.999	0.000
rs4149056 lBF = `-0.0420678` Chr`12` : `21,331,549`	0.001	0.999	0.000
rs11104877 lBF = `-0.0453462` Chr`12` : `88,837,244`	0.000	0.999	0.001
rs4765913 lBF = `-0.0639315` Chr`12` : `2,419,896`	0.000	0.999	0.000
rs6539247 lBF = `-0.064487` Chr`12` : `106,459,902`	0.001	0.999	0.000
rs35767 lBF = `-0.0761637` Chr`12` : `102,875,569`	0.000	0.999	0.001
rs6488619 lBF = `-0.0880297` Chr`12` : `13,927,896`	0.000	0.999	0.001
rs12824981 lBF = `-0.0966397` Chr`12` : `129,637,348`	0.000	0.999	0.001
rs17630235 lBF = `80.0182` Chr`12` : `112,591,686`	0.001	0.999	0.000
rs74452899 lBF = `12.3113` Chr`12` : `89,024,239`	0.000	0.999	0.000
rs117559199 lBF = `8.42044` Chr`12` : `75,424,551`	0.000	0.999	0.000
rs1716403 lBF = `0.583299` Chr`12` : `124,519,846`	0.001	0.999	0.000
rs12580543 lBF = `0.102356` Chr`12` : `7,100,973`	0.000	0.999	0.001
rs12369635 lBF = `0.0404365` Chr`12` : `129,561,356`	0.000	0.999	0.001
rs11051170 lBF = `0.0176364` Chr`12` : `31,085,399`	0.001	0.999	0.000
rs1871395 lBF = `-0.0242603` Chr`12` : `21,352,315`	0.001	0.999	0.000
rs10849432 lBF = `-0.0420753` Chr`12` : `6,385,727`	0.001	0.999	0.000
rs12817211 lBF = `-0.0524559` Chr`12` : `50,579,398`	0.000	0.999	0.000
rs11045879 lBF = `-0.054771` Chr`12` : `21,382,619`	0.001	0.999	0.000
rs4149080 lBF = `-0.0588165` Chr`12` : `21,377,559`	0.001	0.999	0.000
rs11065987 lBF = `90.6309` Chr`12` : `112,072,424`	0.001	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0333

log Bayes Factor = 38.671

contains 2 variants

0.3942

Cluster X0335

log Bayes Factor = 12.3689

contains 1 variants

0.2725

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

0.1557

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

0.9995

Cluster X0059

log Bayes Factor = 922.497

contains 26 variants

0.9987

Cluster X0110

log Bayes Factor = 721.325

contains 13 variants

0.9926

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

0.9840

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

0.9781

Cluster X0222

log Bayes Factor = 431.582

contains 17 variants

0.9596

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

0.9579

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

0.9574

Cluster X0015

log Bayes Factor = 356.23

contains 15 variants

0.9564

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

0.9545

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

0.9528

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

0.9505

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

0.9497

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

0.9492

Cluster X0057

log Bayes Factor = 439.35

contains 16 variants

0.9476

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

0.9454

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

0.9401

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

0.9399

Cluster X0100

log Bayes Factor = 730.252

contains 26 variants

0.9291

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

0.9263

Cluster X0164

log Bayes Factor = 463.793

contains 16 variants

0.9248

Cluster X0148

log Bayes Factor = 315.237

contains 11 variants

0.9176

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

0.9167

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

0.9163

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

0.9150

Cluster X0021

log Bayes Factor = 338.631

contains 13 variants

0.9144

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

0.9138

Cluster X0061

log Bayes Factor = 293.105

contains 15 variants

0.9131

Cluster X0076

log Bayes Factor = 310.928

contains 15 variants

0.9117

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

0.9109

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

0.9103

Cluster X0224

log Bayes Factor = 278.692

contains 11 variants

0.9010

Cluster X0029

log Bayes Factor = 709.102

contains 23 variants

0.8999

Cluster X0268

log Bayes Factor = 213.591

contains 8 variants

0.8924

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

0.8916

Cluster X0146

log Bayes Factor = 686.343

contains 22 variants

0.8905

Cluster X0018

log Bayes Factor = 430.611

contains 18 variants

0.8879

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

0.8874

Cluster X0014

log Bayes Factor = 131.677

contains 6 variants

0.8808

Cluster X0045

log Bayes Factor = 446.264

contains 16 variants

0.8801

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

0.8764

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

0.8740

Cluster X0047

log Bayes Factor = 378.621

contains 14 variants

0.8732

Cluster X0043

log Bayes Factor = 517.108

contains 20 variants

0.8709

Cluster X0082

log Bayes Factor = 496.905

contains 17 variants

0.8691

Cluster X0326

log Bayes Factor = 112.92

contains 5 variants

0.8685

Cluster X0054

log Bayes Factor = 197.338

contains 9 variants

0.8600

Cluster X0274

log Bayes Factor = 454.783

contains 18 variants

0.8592

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

0.8531

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

0.8494

Cluster X0055

log Bayes Factor = 274.911

contains 10 variants

0.8430

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

0.8415

Cluster X0273

log Bayes Factor = 109.896

contains 6 variants

0.8399

Cluster X0159

log Bayes Factor = 152.327

contains 7 variants

0.8324

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

0.8315

Cluster X0257

log Bayes Factor = 281.184

contains 10 variants

0.8303

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

0.8275

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

0.8261

Cluster X0088

log Bayes Factor = 243.609

contains 9 variants

0.8240

Cluster X0184

log Bayes Factor = 188.416

contains 8 variants

0.8222

Cluster X0210

log Bayes Factor = 426.159

contains 17 variants

0.8213

Cluster X0081

log Bayes Factor = 278.568

contains 10 variants

0.8198

Cluster X0095

log Bayes Factor = 179.348

contains 8 variants

0.8186

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

0.8154

Cluster X0180

log Bayes Factor = 410.88

contains 15 variants

0.8131

Cluster X0137

log Bayes Factor = 120.748

contains 4 variants

0.8041

Cluster X0068

log Bayes Factor = 127.774

contains 6 variants

0.7972

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

0.7968

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

0.7922

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

0.7897

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

0.7809

Cluster X0001

log Bayes Factor = 167.541

contains 7 variants

0.7788

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

0.7768

Cluster X0070

log Bayes Factor = 421.182

contains 15 variants

0.7768

Cluster X0165

log Bayes Factor = 303.727

contains 12 variants

0.7766

Cluster X0189

log Bayes Factor = 149.681

contains 5 variants

0.7751

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

0.7718

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

0.7668

Cluster X0156

log Bayes Factor = 226.954

contains 9 variants

0.7638

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

0.7626

Cluster X0003

log Bayes Factor = 195.6

contains 8 variants

0.7595

Cluster X0279

log Bayes Factor = 52.8832

contains 2 variants

0.7589

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

0.7577

Cluster X0153

log Bayes Factor = 328.394

contains 11 variants

0.7501

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

0.7482

Cluster X0046

log Bayes Factor = 387.972

contains 16 variants

0.7244

Cluster X0166

log Bayes Factor = 230.746

contains 8 variants

0.7244

Cluster X0145

log Bayes Factor = 274.587

contains 11 variants

0.7217

Cluster X0229

log Bayes Factor = 347.165

contains 13 variants

0.7133

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

0.7047

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

0.7042

Cluster X0244

log Bayes Factor = 122.647

contains 5 variants

0.6917

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

0.6888

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

0.6831

Cluster X0152

log Bayes Factor = 331.156

contains 10 variants

0.6814

Cluster X0214

log Bayes Factor = 186.582

contains 8 variants

0.6812

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

0.6757

Cluster X0098

log Bayes Factor = 246.226

contains 8 variants

0.6644

Cluster X0067

log Bayes Factor = 179.381

contains 8 variants

0.6643

Cluster X0058

log Bayes Factor = 183.199

contains 8 variants

0.6502

Cluster X0039

log Bayes Factor = 463.231

contains 17 variants

0.6481

Cluster X0226

log Bayes Factor = 145.726

contains 8 variants

0.6437

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

0.6339

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

0.6312

Cluster X0063

log Bayes Factor = 107.557

contains 5 variants

0.6235

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

0.6214

Cluster X0234

log Bayes Factor = 28.8983

contains 2 variants

0.6202

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

0.6118

Cluster X0120

log Bayes Factor = 79.6695

contains 4 variants

0.6109

Cluster X0012

log Bayes Factor = 112.432

contains 5 variants

0.5981

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

0.5762

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

0.5569

Cluster X0085

log Bayes Factor = 138.902

contains 6 variants

0.5404

Cluster X0132

log Bayes Factor = 267.393

contains 11 variants

0.5376

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

0.5139

Cluster X0079

log Bayes Factor = 413.803

contains 22 variants

0.4928

Cluster X0264

log Bayes Factor = 205.833

contains 10 variants

0.4889

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

0.4489

Cluster X0050

log Bayes Factor = 397.79

contains 16 variants

0.4418

Cluster X0237

log Bayes Factor = 123.902

contains 6 variants

0.4248

Cluster X0293

log Bayes Factor = 169.051

contains 7 variants

0.4143

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

0.3968

Cluster X0157

log Bayes Factor = 172.957

contains 8 variants

0.3156

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

0.2987

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

0.2851

Cluster X0138

log Bayes Factor = 43.7891

contains 4 variants

0.2706

Cluster X0227

log Bayes Factor = 249.287

contains 11 variants

0.1286

Cluster X0109

log Bayes Factor = 257.685

contains 11 variants

0.1229

Cluster X0140

log Bayes Factor = 164.536

contains 8 variants

0.1176

Cluster X0074

log Bayes Factor = 353.38

contains 15 variants

0.1147

Cluster X0052

log Bayes Factor = 654.387

contains 25 variants

0.1138

Cluster X0013

log Bayes Factor = 548.265

contains 23 variants

0.1113

Cluster X0107

log Bayes Factor = 151.016

contains 1 variants

0.1056

Cluster X0154

log Bayes Factor = 282.084

contains 12 variants

0.0995

Cluster X0216

log Bayes Factor = 162.135

contains 6 variants

0.0968

Cluster X0324

log Bayes Factor = 32.1341

contains 1 variants

0.0858

Cluster X0028

log Bayes Factor = 120.445

contains 7 variants

0.0825

Cluster X0084

log Bayes Factor = 433.078

contains 21 variants

0.0668

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

0.0609

Cluster X0086

log Bayes Factor = 131.002

contains 8 variants

0.0593

Cluster X0249

log Bayes Factor = 244.457

contains 11 variants

0.0553

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Diagnostic term associations

Hospitalization Episode Statistics (`HES`)

(posterior probability > 0.05)

(posterior probability > 0.05)

Diagnostic term associations

Hospitalization Episode Statistics (HES)

(posterior probability > 0.05)

(posterior probability > 0.05)

Hospitalization Episode Statistics (`HES`)