TreeWAS – [C21] Malignant neoplasm of anus and anal canal

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Diagnostic term associations

Hospitalization Episode Statistics (`HES`)

C21

Malignant neoplasm of anus and anal canal

Parent term	C15-C26 Malignant neoplasms of digestive organs
Nested terms	C21.0 Anus, unspecified C21.1 Anal canal C21.2 Cloacogenic zone C21.8 Overlapping lesion of rectum, anus and anal canal

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Variant effects

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
Affx-28486470 lBF = `253.054` Chr`6` : `32,546,879`	1.000	0.000	0.000
rs111834747 lBF = `248.946` Chr`6` : `32,492,866`	1.000	0.000	0.000
rs9268923 lBF = `248.283` Chr`6` : `32,432,835`	1.000	0.000	0.000
rs3208409 lBF = `252.426` Chr`6` : `32,546,696`	1.000	0.000	0.000
rs9268969 lBF = `249.147` Chr`6` : `32,434,349`	1.000	0.000	0.000
rs9268905 lBF = `248.25` Chr`6` : `32,432,077`	1.000	0.000	0.000
rs28366302 lBF = `252.399` Chr`6` : `32,560,934`	1.000	0.000	0.000
rs9268853 lBF = `248.885` Chr`6` : `32,429,643`	1.000	0.000	0.000
rs9273339 lBF = `437.281` Chr`6` : `32,623,430`	0.000	0.000	1.000
rs28724008 lBF = `253.172` Chr`6` : `32,550,550`	1.000	0.000	0.000
rs2395185 lBF = `246.003` Chr`6` : `32,433,167`	1.000	0.000	0.000
rs477515 lBF = `222.226` Chr`6` : `32,569,691`	1.000	0.000	0.000
rs34839759 lBF = `247.024` Chr`6` : `32,546,557`	1.000	0.000	0.000
rs9273373 lBF = `453.011` Chr`6` : `32,626,601`	1.000	0.000	0.000
rs9273215 lBF = `440.214` Chr`6` : `32,613,712`	0.000	0.000	1.000
rs17843619 lBF = `439.369` Chr`6` : `32,620,775`	0.000	0.000	1.000
rs9272346 lBF = `453.316` Chr`6` : `32,604,372`	1.000	0.000	0.000
rs9273088 lBF = `442.306` Chr`6` : `32,612,488`	0.000	0.000	1.000
rs1063355 lBF = `441.898` Chr`6` : `32,627,714`	0.000	0.000	1.000
rs17612576 lBF = `440.731` Chr`6` : `32,615,458`	0.000	0.000	1.000
rs9274552 lBF = `439.186` Chr`6` : `32,634,838`	0.000	0.000	1.000
rs17843606 lBF = `435.465` Chr`6` : `32,620,399`	0.000	0.000	1.000
Affx-28496566 lBF = `410.258` Chr`6` : `32,625,869`	0.000	0.000	1.000
rs3828790 lBF = `425.616` Chr`6` : `32,635,809`	0.000	0.001	0.999
rs6927022 lBF = `550.507` Chr`6` : `32,612,397`	0.999	0.001	0.000
rs3134996 lBF = `399.72` Chr`6` : `32,636,866`	0.000	0.001	0.999
Affx-37072023 lBF = `455.451` Chr`6` : `32,612,430`	0.000	0.001	0.999
rs4642516 lBF = `196.979` Chr`6` : `32,657,543`	0.999	0.001	0.000
rs6928482 lBF = `193.346` Chr`6` : `32,626,249`	0.999	0.001	0.000
rs9273349 lBF = `389.4` Chr`6` : `32,625,869`	0.998	0.002	0.000
rs9274697 lBF = `191.248` Chr`6` : `32,637,016`	0.997	0.003	0.000
rs9275563 lBF = `193.206` Chr`6` : `32,677,912`	0.993	0.007	0.000
rs9268835 lBF = `269.889` Chr`6` : `32,428,115`	0.991	0.009	0.000
rs35242582 lBF = `194.11` Chr`6` : `32,600,057`	0.000	0.010	0.990
rs17211510 lBF = `186.894` Chr`6` : `32,602,430`	0.000	0.010	0.990
rs443198 lBF = `204.432` Chr`6` : `32,190,406`	0.990	0.010	0.000
rs9268833 lBF = `269.572` Chr`6` : `32,428,062`	0.982	0.018	0.000
rs915895 lBF = `208.157` Chr`6` : `32,190,217`	0.972	0.028	0.000
rs3763311 lBF = `203.85` Chr`6` : `32,376,176`	0.961	0.039	0.000
rs9268499 lBF = `201.124` Chr`6` : `32,375,695`	0.960	0.040	0.000
rs2854050 lBF = `78.2612` Chr`6` : `32,185,605`	0.957	0.043	0.000
rs28366353 lBF = `175.657` Chr`6` : `32,565,004`	0.957	0.043	0.000
rs9268480 lBF = `205.885` Chr`6` : `32,363,844`	0.955	0.045	0.000
rs9268459 lBF = `204.967` Chr`6` : `32,350,776`	0.955	0.045	0.000
rs9268481 lBF = `204.836` Chr`6` : `32,364,356`	0.954	0.046	0.000
rs9268644 lBF = `155.635` Chr`6` : `32,408,044`	0.000	0.048	0.952
rs9268403 lBF = `206.094` Chr`6` : `32,341,473`	0.952	0.048	0.000
rs3763316 lBF = `205.685` Chr`6` : `32,376,746`	0.950	0.050	0.000
rs3763307 lBF = `200.492` Chr`6` : `32,374,622`	0.950	0.050	0.000
rs2555469 lBF = `76.5082` Chr`6` : `32,179,494`	0.950	0.050	0.000
rs9268429 lBF = `204.835` Chr`6` : `32,345,052`	0.949	0.051	0.000
rs9268418 lBF = `204.537` Chr`6` : `32,343,686`	0.948	0.052	0.000
rs9268474 lBF = `206.823` Chr`6` : `32,357,165`	0.948	0.052	0.000
rs2854047 lBF = `77.4353` Chr`6` : `32,179,432`	0.948	0.052	0.000
rs3817963 lBF = `197.964` Chr`6` : `32,368,087`	0.947	0.053	0.000
rs9268428 lBF = `204.585` Chr`6` : `32,344,973`	0.947	0.053	0.000
rs915894 lBF = `219.818` Chr`6` : `32,190,390`	0.947	0.053	0.000
rs9276826 lBF = `16.7625` Chr`6` : `32,830,568`	0.000	0.054	0.946
rs2071285 lBF = `78.0918` Chr`6` : `32,180,431`	0.946	0.054	0.000
rs9268514 lBF = `207.251` Chr`6` : `32,378,945`	0.943	0.057	0.000
rs8192575 lBF = `77.0171` Chr`6` : `32,166,384`	0.941	0.059	0.000
rs9268516 lBF = `206.395` Chr`6` : `32,379,489`	0.935	0.065	0.000
rs2076525 lBF = `201.524` Chr`6` : `32,370,616`	0.935	0.065	0.000
rs41268932 lBF = `84.7067` Chr`6` : `32,154,711`	0.931	0.069	0.000
rs3817962 lBF = `207.082` Chr`6` : `32,368,314`	0.930	0.070	0.000
rs9272143 lBF = `135.294` Chr`6` : `32,600,803`	0.000	0.073	0.927
rs3817966 lBF = `198.937` Chr`6` : `32,367,847`	0.924	0.076	0.000
rs204993 lBF = `249.805` Chr`6` : `32,155,581`	0.919	0.081	0.000
rs5020946 lBF = `305.522` Chr`6` : `32,450,089`	0.914	0.086	0.000
rs9271824 lBF = `133.849` Chr`6` : `32,594,916`	0.000	0.086	0.914
rs9271858 lBF = `134.701` Chr`6` : `32,595,223`	0.000	0.087	0.913
rs9271720 lBF = `131.714` Chr`6` : `32,593,507`	0.000	0.097	0.903
rs72849247 lBF = `90.4818` Chr`6` : `32,453,194`	0.000	0.103	0.897
rs13192471 lBF = `84.1735` Chr`6` : `32,671,103`	0.000	0.107	0.893
rs6916062 lBF = `69.9973` Chr`6` : `32,219,041`	0.892	0.108	0.000
rs879882 lBF = `53.6059` Chr`6` : `31,139,452`	0.000	0.109	0.891
rs28732193 lBF = `69.6869` Chr`6` : `32,306,922`	0.891	0.109	0.000
rs28732233 lBF = `67.2768` Chr`6` : `32,427,699`	0.890	0.110	0.000
rs12194148 lBF = `308.912` Chr`6` : `32,444,198`	0.890	0.110	0.000
rs9378212 lBF = `308.89` Chr`6` : `32,445,691`	0.890	0.110	0.000
rs28732201 lBF = `63.8841` Chr`6` : `32,350,454`	0.889	0.111	0.000
rs28895243 lBF = `68.4375` Chr`6` : `32,443,799`	0.889	0.111	0.000
rs9468831 lBF = `13.0168` Chr`6` : `30,749,844`	0.889	0.111	0.000
rs28732236 lBF = `68.0491` Chr`6` : `32,430,976`	0.888	0.112	0.000
rs8192591 lBF = `69.5055` Chr`6` : `32,185,796`	0.888	0.112	0.000
rs9268839 lBF = `309.386` Chr`6` : `32,428,772`	0.886	0.114	0.000
rs9268456 lBF = `206.36` Chr`6` : `32,349,946`	0.886	0.114	0.000
rs9368737 lBF = `148.543` Chr`6` : `32,658,429`	0.883	0.117	0.000
rs17776284 lBF = `12.0857` Chr`6` : `28,196,454`	0.882	0.118	0.000
rs2299031 lBF = `13.2378` Chr`6` : `28,196,718`	0.878	0.122	0.000
rs73425733 lBF = `14.1421` Chr`6` : `30,748,297`	0.870	0.130	0.000
rs1704996 lBF = `30.724` Chr`6` : `33,182,895`	0.870	0.130	0.000
rs204999 lBF = `225.279` Chr`6` : `32,109,979`	0.861	0.139	0.000
rs9272105 lBF = `131.969` Chr`6` : `32,599,999`	0.000	0.140	0.860
rs11575907 lBF = `33.192` Chr`6` : `32,782,112`	0.854	0.146	0.000
rs6911419 lBF = `160.092` Chr`6` : `32,409,787`	0.837	0.163	0.000
rs2856718 lBF = `145.895` Chr`6` : `32,670,255`	0.832	0.168	0.000
rs2516484 lBF = `81.6627` Chr`6` : `31,496,381`	0.831	0.169	0.000
rs111461772 lBF = `26.9073` Chr`6` : `33,373,953`	0.828	0.172	0.000
rs2647050 lBF = `146.729` Chr`6` : `32,669,767`	0.827	0.173	0.000
rs17615250 lBF = `142.837` Chr`6` : `32,678,973`	0.827	0.173	0.000
rs16898264 lBF = `146.028` Chr`6` : `32,677,152`	0.826	0.174	0.000
rs9272116 lBF = `128.058` Chr`6` : `32,600,404`	0.000	0.175	0.825
Affx-52368556 lBF = `236.51` Chr`6` : `31,084,935`	0.825	0.175	0.000
rs62387661 lBF = `9.25318` Chr`6` : `16,084,392`	0.820	0.180	0.000
rs4134947 lBF = `11.4935` Chr`6` : `20,483,770`	0.820	0.180	0.000
rs78288301 lBF = `12.7347` Chr`6` : `33,887,984`	0.817	0.182	0.000
rs6931646 lBF = `159.643` Chr`6` : `32,409,781`	0.817	0.183	0.000
rs34182778 lBF = `229.887` Chr`6` : `31,084,942`	0.816	0.184	0.000
rs9263708 lBF = `251.317` Chr`6` : `31,095,270`	0.815	0.185	0.000
rs6926374 lBF = `161.774` Chr`6` : `32,409,305`	0.809	0.191	0.000
rs2239804 lBF = `160.308` Chr`6` : `32,411,523`	0.808	0.192	0.000
rs3094216 lBF = `239.383` Chr`6` : `31,084,048`	0.808	0.192	0.000
rs4410767 lBF = `309.439` Chr`6` : `32,448,129`	0.807	0.193	0.000
rs9268401 lBF = `190.875` Chr`6` : `32,341,318`	0.804	0.196	0.000
rs3132550 lBF = `240.835` Chr`6` : `31,086,048`	0.803	0.197	0.000
rs59440261 lBF = `89.4301` Chr`6` : `31,371,071`	0.802	0.198	0.000
rs9368699 lBF = `80.8974` Chr`6` : `31,802,541`	0.799	0.201	0.000
rs117362018 lBF = `29.1711` Chr`6` : `78,246,632`	0.799	0.201	0.000
rs3130564 lBF = `267.188` Chr`6` : `31,101,674`	0.794	0.206	0.000
rs3095298 lBF = `239.113` Chr`6` : `31,082,932`	0.794	0.206	0.000
rs9275596 lBF = `302.815` Chr`6` : `32,681,631`	0.000	0.208	0.792
rs79570361 lBF = `48.293` Chr`6` : `161,170,855`	0.791	0.209	0.000
rs3094220 lBF = `239.557` Chr`6` : `31,082,987`	0.789	0.211	0.000
rs3093668 lBF = `82.8967` Chr`6` : `31,546,495`	0.784	0.216	0.000
rs35650677 lBF = `25.285` Chr`6` : `22,078,097`	0.779	0.221	0.000
rs7741164 lBF = `16.6103` Chr`6` : `41,493,412`	0.776	0.224	0.000
rs3096697 lBF = `98.9911` Chr`6` : `32,134,510`	0.771	0.229	0.000
rs3131297 lBF = `98.8204` Chr`6` : `32,141,005`	0.771	0.229	0.000
rs17212937 lBF = `111.386` Chr`6` : `32,681,339`	0.768	0.232	0.000
rs76086850 lBF = `17.5203` Chr`6` : `152,508,097`	0.768	0.232	0.000
rs28732081 lBF = `101.638` Chr`6` : `31,002,343`	0.767	0.233	0.000
rs2496644 lBF = `15.9721` Chr`6` : `41,482,745`	0.765	0.235	0.000
rs7356880 lBF = `52.8273` Chr`6` : `32,401,327`	0.764	0.236	0.000
rs3134944 lBF = `102.616` Chr`6` : `32,146,644`	0.763	0.237	0.000
rs3134947 lBF = `100.76` Chr`6` : `32,145,205`	0.760	0.240	0.000
rs3096696 lBF = `97.6499` Chr`6` : `32,122,472`	0.759	0.241	0.000
rs3132965 lBF = `101.313` Chr`6` : `32,146,997`	0.759	0.241	0.000
rs3134946 lBF = `101.407` Chr`6` : `32,145,993`	0.757	0.243	0.000
rs2495244 lBF = `8.29163` Chr`6` : `41,495,339`	0.757	0.243	0.000
rs3134945 lBF = `100.753` Chr`6` : `32,146,492`	0.756	0.244	0.000
rs79131379 lBF = `30.3412` Chr`6` : `33,133,040`	0.752	0.248	0.000
rs3130284 lBF = `104.467` Chr`6` : `32,140,487`	0.751	0.249	0.000
rs29001568 lBF = `291.101` Chr`6` : `32,447,341`	0.750	0.250	0.000
rs17083533 lBF = `1.99367` Chr`6` : `121,730,722`	0.749	0.251	0.000
rs79758531 lBF = `13.2883` Chr`6` : `30,736,010`	0.749	0.251	0.000
rs3130347 lBF = `380.111` Chr`6` : `32,134,656`	0.746	0.254	0.000
rs80215559 lBF = `40.8472` Chr`6` : `25,918,225`	0.743	0.257	0.000
rs7765379 lBF = `110.484` Chr`6` : `32,680,928`	0.742	0.258	0.000
rs715299 lBF = `48.7211` Chr`6` : `32,189,841`	0.741	0.258	0.000
rs3021366 lBF = `84.3767` Chr`6` : `31,445,771`	0.738	0.262	0.000
rs79330198 lBF = `10.5628` Chr`6` : `69,595,040`	0.738	0.262	0.000
rs113232354 lBF = `23.1151` Chr`6` : `51,855,211`	0.738	0.262	0.000
rs3129720 lBF = `342.091` Chr`6` : `32,663,631`	0.737	0.263	0.000
rs116446171 lBF = `3.80986` Chr`6` : `484,453`	0.736	0.264	0.000
rs75018213 lBF = `22.9297` Chr`6` : `146,052,178`	0.735	0.264	0.000
rs2856717 lBF = `292.518` Chr`6` : `32,670,308`	0.000	0.265	0.735
rs204995 lBF = `73.8651` Chr`6` : `32,154,285`	0.731	0.269	0.000
rs9493873 lBF = `5.52086` Chr`6` : `134,576,511`	0.730	0.270	0.000
rs176095 lBF = `360.117` Chr`6` : `32,158,319`	0.730	0.270	0.000
rs1800562 lBF = `34.2038` Chr`6` : `26,093,141`	0.727	0.273	0.000
rs2239803 lBF = `162.7` Chr`6` : `32,411,833`	0.727	0.273	0.000
rs74754122 lBF = `23.2295` Chr`6` : `145,961,790`	0.725	0.275	0.000
Affx-28471757 lBF = `171.957` Chr`6` : `32,313,659`	0.717	0.283	0.000
rs118008540 lBF = `14.4387` Chr`6` : `111,739,245`	0.717	0.283	0.000
rs75754936 lBF = `9.36846` Chr`6` : `122,770,192`	0.717	0.283	0.000
rs172330 lBF = `26.9607` Chr`6` : `28,786,884`	0.714	0.285	0.000
rs2647003 lBF = `291.553` Chr`6` : `32,664,880`	0.000	0.286	0.714
rs55669504 lBF = `14.7281` Chr`6` : `32,942,354`	0.713	0.287	0.000
rs116428066 lBF = `13.3167` Chr`6` : `9,983,924`	0.712	0.288	0.000
rs204992 lBF = `357.269` Chr`6` : `32,156,908`	0.712	0.288	0.000
rs116855070 lBF = `11.8145` Chr`6` : `137,922,391`	0.710	0.290	0.000
rs115413613 lBF = `22.5701` Chr`6` : `25,471,772`	0.708	0.292	0.000
rs2858310 lBF = `295.324` Chr`6` : `32,668,323`	0.708	0.292	0.000
rs11557308 lBF = `22.8654` Chr`6` : `31,431,403`	0.707	0.293	0.000
rs114477071 lBF = `15.5877` Chr`6` : `14,938,860`	0.707	0.293	0.000
rs34075049 lBF = `85.0932` Chr`6` : `32,554,935`	0.705	0.295	0.000
rs3134608 lBF = `99.9061` Chr`6` : `32,117,971`	0.704	0.296	0.000
rs75807633 lBF = `18.3777` Chr`6` : `135,495,020`	0.704	0.296	0.000
rs74566653 lBF = `14.3561` Chr`6` : `49,033,485`	0.704	0.296	0.000
rs114059502 lBF = `12.4556` Chr`6` : `30,837,290`	0.703	0.297	0.000
rs56057304 lBF = `23.4116` Chr`6` : `28,207,991`	0.703	0.297	0.000
rs9275602 lBF = `368.479` Chr`6` : `32,682,812`	0.701	0.299	0.000
rs62620225 lBF = `21.196` Chr`6` : `28,117,331`	0.701	0.299	0.000
rs4151659 lBF = `46.172` Chr`6` : `31,918,464`	0.699	0.301	0.000
rs115138709 lBF = `23.7047` Chr`6` : `31,430,600`	0.699	0.301	0.000
rs6918090 lBF = `57.3438` Chr`6` : `33,854,733`	0.699	0.301	0.000
rs16889916 lBF = `20.7757` Chr`6` : `24,989,384`	0.698	0.302	0.000
rs9268233 lBF = `33.0857` Chr`6` : `32,289,292`	0.697	0.303	0.000
rs75270276 lBF = `17.6361` Chr`6` : `168,552,585`	0.697	0.303	0.000
rs114496068 lBF = `15.6666` Chr`6` : `49,705,603`	0.696	0.304	0.000
rs182679717 lBF = `13.1183` Chr`6` : `41,975,693`	0.695	0.305	0.000
rs9269081 lBF = `250.357` Chr`6` : `32,441,100`	0.000	0.307	0.693
rs9276427 lBF = `129.169` Chr`6` : `32,711,857`	0.693	0.307	0.000
rs77803816 lBF = `19.635` Chr`6` : `31,431,063`	0.692	0.308	0.000
rs9501624 lBF = `61.2049` Chr`6` : `32,399,286`	0.692	0.308	0.000
rs2523722 lBF = `183.887` Chr`6` : `30,165,273`	0.689	0.311	0.000
rs143099908 lBF = `18.5844` Chr`6` : `27,667,247`	0.688	0.312	0.000
rs80123541 lBF = `17.2266` Chr`6` : `110,354,662`	0.687	0.312	0.000
rs9266340 lBF = `17.9247` Chr`6` : `31,331,306`	0.686	0.314	0.000
rs75098702 lBF = `19.4806` Chr`6` : `44,618,970`	0.686	0.314	0.000
rs9266417 lBF = `17.1829` Chr`6` : `31,336,994`	0.686	0.314	0.000
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rs9262176 lBF = `13.9578` Chr`6` : `30,731,330`	0.519	0.480	0.000
rs501220 lBF = `90.8209` Chr`6` : `25,873,025`	0.518	0.482	0.000
rs3806156 lBF = `139.984` Chr`6` : `32,373,698`	0.518	0.482	0.000
rs7772289 lBF = `47.6229` Chr`6` : `28,674,322`	0.517	0.483	0.000
rs9467714 lBF = `110.852` Chr`6` : `26,340,785`	0.517	0.483	0.000
rs205000 lBF = `21.2147` Chr`6` : `32,135,878`	0.516	0.484	0.000
rs9274623 lBF = `234.77` Chr`6` : `32,635,998`	0.516	0.484	0.000
rs9267660 lBF = `19.9749` Chr`6` : `31,851,884`	0.515	0.485	0.000
rs13198474 lBF = `116.097` Chr`6` : `25,874,423`	0.514	0.486	0.000
rs17189749 lBF = `17.6121` Chr`6` : `30,904,535`	0.514	0.486	0.000
rs12662228 lBF = `11.7641` Chr`6` : `55,191,559`	0.514	0.486	0.000
rs1165168 lBF = `95.143` Chr`6` : `25,859,508`	0.513	0.487	0.000
rs13200797 lBF = `98.3608` Chr`6` : `26,122,957`	0.511	0.489	0.000
rs929157 lBF = `232.182` Chr`6` : `30,137,209`	0.511	0.489	0.000
rs16891315 lBF = `91.5417` Chr`6` : `26,111,756`	0.510	0.490	0.000
rs2232423 lBF = `201.397` Chr`6` : `28,366,151`	0.509	0.490	0.000
rs75932628 lBF = `0.8455` Chr`6` : `41,129,252`	0.507	0.493	0.000
rs219976 lBF = `9.00082` Chr`6` : `12,199,517`	0.505	0.495	0.000
rs548987 lBF = `92.1448` Chr`6` : `25,869,371`	0.503	0.496	0.000
rs74695365 lBF = `20.1023` Chr`6` : `33,991,692`	0.503	0.497	0.000
rs57740770 lBF = `14.7225` Chr`6` : `32,067,435`	0.502	0.498	0.000
rs61748588 lBF = `24.9135` Chr`6` : `30,878,523`	0.501	0.498	0.000
rs113310853 lBF = `16.828` Chr`6` : `31,405,598`	0.500	0.500	0.000
rs6940698 lBF = `103.27` Chr`6` : `25,821,580`	0.500	0.500	0.000
rs3117143 lBF = `207.034` Chr`6` : `29,031,142`	0.499	0.500	0.000
rs1324088 lBF = `94.6116` Chr`6` : `25,841,122`	0.498	0.501	0.000
rs116795853 lBF = `17.0163` Chr`6` : `31,373,985`	0.498	0.502	0.000
rs2765220 lBF = `145.929` Chr`6` : `28,769,671`	0.497	0.502	0.000
rs16891235 lBF = `94.1744` Chr`6` : `26,017,542`	0.497	0.503	0.000
rs3118361 lBF = `208.226` Chr`6` : `28,898,287`	0.496	0.503	0.000
rs2076523 lBF = `139.68` Chr`6` : `32,370,835`	0.496	0.504	0.000
rs715044 lBF = `27.9833` Chr`6` : `29,593,788`	0.494	0.506	0.000
rs1233579 lBF = `197.386` Chr`6` : `28,712,663`	0.493	0.507	0.000
rs3117439 lBF = `205.088` Chr`6` : `29,266,483`	0.493	0.507	0.000
rs9461908 lBF = `53.4251` Chr`6` : `33,736,082`	0.492	0.508	0.000
rs67340775 lBF = `199.939` Chr`6` : `28,304,384`	0.491	0.509	0.000
rs9359466 lBF = `16.1014` Chr`6` : `81,935,652`	0.490	0.509	0.000
rs6927354 lBF = `1.01443` Chr`6` : `6,316,313`	0.490	0.510	0.000
rs73404209 lBF = `16.4855` Chr`6` : `31,405,671`	0.490	0.510	0.000
rs3094694 lBF = `198.27` Chr`6` : `30,451,904`	0.489	0.510	0.000
rs13194504 lBF = `204.013` Chr`6` : `28,630,691`	0.488	0.512	0.000
rs3118357 lBF = `210.247` Chr`6` : `28,802,149`	0.487	0.512	0.000
rs660895 lBF = `476.437` Chr`6` : `32,577,380`	0.488	0.512	0.000
rs260262 lBF = `17.6741` Chr`6` : `42,428,634`	0.487	0.513	0.000
rs3117425 lBF = `206.73` Chr`6` : `29,260,431`	0.486	0.514	0.000
rs3131073 lBF = `202.423` Chr`6` : `28,920,972`	0.486	0.514	0.000
rs10947233 lBF = `77.0081` Chr`6` : `32,124,424`	0.486	0.514	0.000
rs13211507 lBF = `197.103` Chr`6` : `28,257,377`	0.485	0.514	0.000
rs3129831 lBF = `214.164` Chr`6` : `30,234,627`	0.484	0.516	0.000
rs13196552 lBF = `92.1189` Chr`6` : `25,974,204`	0.484	0.516	0.000
rs1311918 lBF = `208.355` Chr`6` : `28,753,646`	0.483	0.516	0.000
rs73725220 lBF = `7.2576` Chr`6` : `16,700,060`	0.483	0.517	0.000
rs3130552 lBF = `228.001` Chr`6` : `31,082,127`	0.483	0.517	0.000
rs4324798 lBF = `208.631` Chr`6` : `28,776,117`	0.482	0.517	0.000
rs3132392 lBF = `212.95` Chr`6` : `28,838,629`	0.482	0.517	0.000
rs75796365 lBF = `0.661072` Chr`6` : `143,362,753`	0.482	0.518	0.000
rs13217619 lBF = `199.852` Chr`6` : `28,306,671`	0.481	0.518	0.000
rs16891334 lBF = `95.5097` Chr`6` : `26,124,303`	0.481	0.519	0.000
rs3118359 lBF = `213.695` Chr`6` : `28,793,904`	0.480	0.519	0.001
rs9468474 lBF = `20.5637` Chr`6` : `29,013,133`	0.481	0.519	0.000
rs9257248 lBF = `208.12` Chr`6` : `28,803,291`	0.479	0.520	0.000
rs144447022 lBF = `217.73` Chr`6` : `29,244,219`	0.479	0.521	0.000
rs9276644 lBF = `145.002` Chr`6` : `32,745,043`	0.479	0.521	0.000
rs116869525 lBF = `4.44373` Chr`6` : `32,389,143`	0.479	0.521	0.000
rs3129837 lBF = `231.864` Chr`6` : `30,306,306`	0.479	0.521	0.000
rs3130834 lBF = `217.35` Chr`6` : `29,248,149`	0.479	0.521	0.001
rs2282143 lBF = `124.222` Chr`6` : `160,557,643`	0.479	0.521	0.000
rs368735 lBF = `6.01789` Chr`6` : `18,293,832`	0.478	0.522	0.000
rs2395029 lBF = `87.593` Chr`6` : `31,431,780`	0.478	0.522	0.000
rs17301128 lBF = `90.5348` Chr`6` : `28,308,034`	0.478	0.522	0.000
rs1233619 lBF = `203.327` Chr`6` : `28,745,452`	0.478	0.522	0.000
rs1265065 lBF = `18.5675` Chr`6` : `31,077,724`	0.478	0.522	0.000
rs7767099 lBF = `208.838` Chr`6` : `28,768,698`	0.477	0.523	0.000
rs3129788 lBF = `213.388` Chr`6` : `29,057,639`	0.477	0.523	0.000
rs3130845 lBF = `210.244` Chr`6` : `28,923,367`	0.476	0.523	0.000
rs2507997 lBF = `261.668` Chr`6` : `31,314,781`	0.477	0.523	0.000
rs13212534 lBF = `117.616` Chr`6` : `25,983,010`	0.476	0.523	0.000
rs3130893 lBF = `213.192` Chr`6` : `28,980,707`	0.475	0.524	0.001
rs113901367 lBF = `17.9835` Chr`6` : `31,382,015`	0.475	0.525	0.000
rs111331141 lBF = `13.3373` Chr`6` : `31,400,947`	0.475	0.525	0.000
rs72907046 lBF = `20.2521` Chr`6` : `82,127,883`	0.475	0.525	0.000
rs79165228 lBF = `12.9482` Chr`6` : `34,796,454`	0.475	0.525	0.000
rs9268541 lBF = `12.7304` Chr`6` : `32,384,527`	0.474	0.525	0.000
rs2517645 lBF = `222.009` Chr`6` : `30,122,623`	0.474	0.526	0.000
rs6903652 lBF = `89.1572` Chr`6` : `28,322,120`	0.474	0.526	0.000
rs6921919 lBF = `92.1777` Chr`6` : `28,325,201`	0.473	0.527	0.000
rs6922111 lBF = `93.7796` Chr`6` : `28,325,308`	0.472	0.527	0.000
rs3131343 lBF = `208.216` Chr`6` : `28,775,564`	0.472	0.528	0.001
rs117291711 lBF = `13.4753` Chr`6` : `77,342,861`	0.472	0.528	0.000
rs3130838 lBF = `210.533` Chr`6` : `28,866,528`	0.471	0.528	0.000
rs6912584 lBF = `87.9417` Chr`6` : `28,309,590`	0.471	0.528	0.000
rs117293402 lBF = `14.7593` Chr`6` : `110,946,140`	0.471	0.529	0.000
rs9271588 lBF = `289.695` Chr`6` : `32,590,953`	0.000	0.530	0.470
rs3129791 lBF = `212.141` Chr`6` : `28,954,293`	0.469	0.531	0.001
rs117951181 lBF = `15.9596` Chr`6` : `167,523,778`	0.468	0.532	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0027

log Bayes Factor = 25.8087

contains 2 variants

0.7968

Cluster X0333

log Bayes Factor = 38.671

contains 2 variants

0.6498

Cluster X0289

log Bayes Factor = 60.4564

contains 1 variants

0.4586

Cluster X0317

log Bayes Factor = 95.4365

contains 2 variants

0.2458

Cluster X0186

log Bayes Factor = 35.9761

contains 2 variants

0.2181

Cluster X0160

log Bayes Factor = 99.5328

contains 9 variants

0.0632

Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0072

log Bayes Factor = 1189.98

contains 37 variants

1.0000

Cluster X0053

log Bayes Factor = 218.825

contains 12 variants

0.9993

Cluster X0100

log Bayes Factor = 730.252

contains 26 variants

0.9990

Cluster X0180

log Bayes Factor = 410.88

contains 15 variants

0.9989

Cluster X0106

log Bayes Factor = 980.916

contains 30 variants

0.9977

Cluster X0084

log Bayes Factor = 433.078

contains 21 variants

0.9947

Cluster X0124

log Bayes Factor = 336.468

contains 13 variants

0.9947

Cluster X0274

log Bayes Factor = 454.783

contains 18 variants

0.9932

Cluster X0048

log Bayes Factor = 358.819

contains 19 variants

0.9928

Cluster X0210

log Bayes Factor = 426.159

contains 17 variants

0.9894

Cluster X0069

log Bayes Factor = 519.392

contains 20 variants

0.9887

Cluster X0133

log Bayes Factor = 224.204

contains 11 variants

0.9860

Cluster X0277

log Bayes Factor = 726.213

contains 23 variants

0.9823

Cluster X0222

log Bayes Factor = 431.582

contains 17 variants

0.9791

Cluster X0148

log Bayes Factor = 315.237

contains 11 variants

0.9773

Cluster X0132

log Bayes Factor = 267.393

contains 11 variants

0.9753

Cluster X0232

log Bayes Factor = 695.273

contains 23 variants

0.9747

Cluster X0094

log Bayes Factor = 562.956

contains 18 variants

0.9745

Cluster X0170

log Bayes Factor = 264.081

contains 11 variants

0.9742

Cluster X0041

log Bayes Factor = 306.192

contains 14 variants

0.9731

Cluster X0117

log Bayes Factor = 453.246

contains 21 variants

0.9727

Cluster X0013

log Bayes Factor = 548.265

contains 23 variants

0.9647

Cluster X0256

log Bayes Factor = 211.588

contains 9 variants

0.9645

Cluster X0154

log Bayes Factor = 282.084

contains 12 variants

0.9629

Cluster X0093

log Bayes Factor = 289.878

contains 10 variants

0.9620

Cluster X0073

log Bayes Factor = 785.614

contains 25 variants

0.9612

Cluster X0185

log Bayes Factor = 84.7127

contains 6 variants

0.9607

Cluster X0070

log Bayes Factor = 421.182

contains 15 variants

0.9606

Cluster X0146

log Bayes Factor = 686.343

contains 22 variants

0.9592

Cluster X0203

log Bayes Factor = 363.522

contains 11 variants

0.9587

Cluster X0276

log Bayes Factor = 187.108

contains 9 variants

0.9578

Cluster X0127

log Bayes Factor = 276.004

contains 14 variants

0.9570

Cluster X0134

log Bayes Factor = 151.731

contains 8 variants

0.9564

Cluster X0123

log Bayes Factor = 382.779

contains 14 variants

0.9530

Cluster X0087

log Bayes Factor = 894.58

contains 26 variants

0.9521

Cluster X0052

log Bayes Factor = 654.387

contains 25 variants

0.9519

Cluster X0264

log Bayes Factor = 205.833

contains 10 variants

0.9503

Cluster X0074

log Bayes Factor = 353.38

contains 15 variants

0.9493

Cluster X0050

log Bayes Factor = 397.79

contains 16 variants

0.9469

Cluster X0150

log Bayes Factor = 861.091

contains 26 variants

0.9439

Cluster X0078

log Bayes Factor = 203.49

contains 11 variants

0.9434

Cluster X0138

log Bayes Factor = 43.7891

contains 4 variants

0.9431

Cluster X0229

log Bayes Factor = 347.165

contains 13 variants

0.9415

Cluster X0164

log Bayes Factor = 463.793

contains 16 variants

0.9405

Cluster X0169

log Bayes Factor = 331.98

contains 16 variants

0.9385

Cluster X0082

log Bayes Factor = 496.905

contains 17 variants

0.9370

Cluster X0109

log Bayes Factor = 257.685

contains 11 variants

0.9365

Cluster X0177

log Bayes Factor = 254.872

contains 10 variants

0.9336

Cluster X0165

log Bayes Factor = 303.727

contains 12 variants

0.9291

Cluster X0044

log Bayes Factor = 1165.44

contains 34 variants

0.9279

Cluster X0043

log Bayes Factor = 517.108

contains 20 variants

0.9261

Cluster X0125

log Bayes Factor = 215.738

contains 7 variants

0.9234

Cluster X0166

log Bayes Factor = 230.746

contains 8 variants

0.9222

Cluster X0059

log Bayes Factor = 922.497

contains 26 variants

0.9209

Cluster X0224

log Bayes Factor = 278.692

contains 11 variants

0.9209

Cluster X0095

log Bayes Factor = 179.348

contains 8 variants

0.9147

Cluster X0259

log Bayes Factor = 246.237

contains 11 variants

0.9127

Cluster X0076

log Bayes Factor = 310.928

contains 15 variants

0.9111

Cluster X0204

log Bayes Factor = 169.796

contains 8 variants

0.9031

Cluster X0249

log Bayes Factor = 244.457

contains 11 variants

0.9026

Cluster X0030

log Bayes Factor = 216.364

contains 9 variants

0.9025

Cluster X0005

log Bayes Factor = 282.915

contains 11 variants

0.9017

Cluster X0263

log Bayes Factor = 240.36

contains 13 variants

0.9007

Cluster X0178

log Bayes Factor = 225.6

contains 9 variants

0.9005

Cluster X0089

log Bayes Factor = 308.747

contains 13 variants

0.8981

Cluster X0015

log Bayes Factor = 356.23

contains 15 variants

0.8978

Cluster X0075

log Bayes Factor = 431.344

contains 16 variants

0.8967

Cluster X0253

log Bayes Factor = 331.491

contains 13 variants

0.8964

Cluster X0252

log Bayes Factor = 170.729

contains 6 variants

0.8933

Cluster X0067

log Bayes Factor = 179.381

contains 8 variants

0.8867

Cluster X0029

log Bayes Factor = 709.102

contains 23 variants

0.8857

Cluster X0019

log Bayes Factor = 372.36

contains 16 variants

0.8853

Cluster X0145

log Bayes Factor = 274.587

contains 11 variants

0.8834

Cluster X0137

log Bayes Factor = 120.748

contains 4 variants

0.8802

Cluster X0091

log Bayes Factor = 303.64

contains 12 variants

0.8790

Cluster X0167

log Bayes Factor = 136.48

contains 6 variants

0.8775

Cluster X0039

log Bayes Factor = 463.231

contains 17 variants

0.8740

Cluster X0045

log Bayes Factor = 446.264

contains 16 variants

0.8740

Cluster X0054

log Bayes Factor = 197.338

contains 9 variants

0.8727

Cluster X0283

log Bayes Factor = 162.98

contains 9 variants

0.8648

Cluster X0047

log Bayes Factor = 378.621

contains 14 variants

0.8571

Cluster X0119

log Bayes Factor = 114.358

contains 6 variants

0.8564

Cluster X0205

log Bayes Factor = 674.183

contains 18 variants

0.8558

Cluster X0213

log Bayes Factor = 405.918

contains 15 variants

0.8555

Cluster X0131

log Bayes Factor = 143.942

contains 8 variants

0.8554

Cluster X0071

log Bayes Factor = 131.269

contains 6 variants

0.8551

Cluster X0126

log Bayes Factor = 384.432

contains 15 variants

0.8535

Cluster X0079

log Bayes Factor = 413.803

contains 22 variants

0.8529

Cluster X0085

log Bayes Factor = 138.902

contains 6 variants

0.8492

Cluster X0290

log Bayes Factor = 333.908

contains 13 variants

0.8488

Cluster X0092

log Bayes Factor = 90.0773

contains 8 variants

0.8467

Cluster X0021

log Bayes Factor = 338.631

contains 13 variants

0.8456

Cluster X0140

log Bayes Factor = 164.536

contains 8 variants

0.8416

Cluster X0218

log Bayes Factor = 425.579

contains 18 variants

0.8410

Cluster X0026

log Bayes Factor = 232.119

contains 9 variants

0.8366

Cluster X0197

log Bayes Factor = 158.582

contains 8 variants

0.8324

Cluster X0077

log Bayes Factor = 571.533

contains 17 variants

0.8321

Cluster X0111

log Bayes Factor = 403.183

contains 18 variants

0.8313

Cluster X0162

log Bayes Factor = 144.479

contains 9 variants

0.8269

Cluster X0258

log Bayes Factor = 104.851

contains 6 variants

0.8237

Cluster X0184

log Bayes Factor = 188.416

contains 8 variants

0.8208

Cluster X0246

log Bayes Factor = 121.08

contains 5 variants

0.8204

Cluster X0032

log Bayes Factor = 255.737

contains 12 variants

0.8176

Cluster X0049

log Bayes Factor = 597.061

contains 18 variants

0.8134

Cluster X0083

log Bayes Factor = 351.917

contains 13 variants

0.8130

Cluster X0086

log Bayes Factor = 131.002

contains 8 variants

0.8095

Cluster X0171

log Bayes Factor = 291.293

contains 14 variants

0.8090

Cluster X0279

log Bayes Factor = 52.8832

contains 2 variants

0.8087

Cluster X0051

log Bayes Factor = 376.793

contains 14 variants

0.8001

Cluster X0176

log Bayes Factor = 407.797

contains 14 variants

0.7957

Cluster X0271

log Bayes Factor = 256.743

contains 10 variants

0.7951

Cluster X0293

log Bayes Factor = 169.051

contains 7 variants

0.7913

Cluster X0081

log Bayes Factor = 278.568

contains 10 variants

0.7897

Cluster X0161

log Bayes Factor = 609.219

contains 20 variants

0.7887

Cluster X0055

log Bayes Factor = 274.911

contains 10 variants

0.7850

Cluster X0261

log Bayes Factor = 420.614

contains 20 variants

0.7849

Cluster X0257

log Bayes Factor = 281.184

contains 10 variants

0.7847

Cluster X0248

log Bayes Factor = 254.854

contains 10 variants

0.7818

Cluster X0057

log Bayes Factor = 439.35

contains 16 variants

0.7807

Cluster X0033

log Bayes Factor = 379.444

contains 13 variants

0.7760

Cluster X0038

log Bayes Factor = 31.1234

contains 2 variants

0.7701

Cluster X0192

log Bayes Factor = 402.511

contains 14 variants

0.7639

Cluster X0174

log Bayes Factor = 214.209

contains 8 variants

0.7566

Cluster X0065

log Bayes Factor = 53.0717

contains 3 variants

0.7432

Cluster X0152

log Bayes Factor = 331.156

contains 10 variants

0.7396

Cluster X0244

log Bayes Factor = 122.647

contains 5 variants

0.7338

Cluster X0142

log Bayes Factor = 295.63

contains 12 variants

0.7303

Cluster X0153

log Bayes Factor = 328.394

contains 11 variants

0.7253

Cluster X0315

log Bayes Factor = 42.686

contains 2 variants

0.7212

Cluster X0098

log Bayes Factor = 246.226

contains 8 variants

0.7169

Cluster X0058

log Bayes Factor = 183.199

contains 8 variants

0.7169

Cluster X0268

log Bayes Factor = 213.591

contains 8 variants

0.7169

Cluster X0214

log Bayes Factor = 186.582

contains 8 variants

0.7153

Cluster X0159

log Bayes Factor = 152.327

contains 7 variants

0.7147

Cluster X0014

log Bayes Factor = 131.677

contains 6 variants

0.7068

Cluster X0037

log Bayes Factor = 171.712

contains 6 variants

0.6972

Cluster X0020

log Bayes Factor = 557.721

contains 18 variants

0.6970

Cluster X0120

log Bayes Factor = 79.6695

contains 4 variants

0.6948

Cluster X0042

log Bayes Factor = 307.243

contains 12 variants

0.6940

Cluster X0237

log Bayes Factor = 123.902

contains 6 variants

0.6920

Cluster X0040

log Bayes Factor = 542.747

contains 16 variants

0.6840

Cluster X0088

log Bayes Factor = 243.609

contains 9 variants

0.6773

Cluster X0003

log Bayes Factor = 195.6

contains 8 variants

0.6520

Cluster X0128

log Bayes Factor = 148.918

contains 15 variants

0.6514

Cluster X0046

log Bayes Factor = 387.972

contains 16 variants

0.6476

Cluster X0273

log Bayes Factor = 109.896

contains 6 variants

0.6396

Cluster X0143

log Bayes Factor = 179.808

contains 8 variants

0.6282

Cluster X0201

log Bayes Factor = 368.049

contains 13 variants

0.6265

Cluster X0024

log Bayes Factor = 309.44

contains 13 variants

0.6264

Cluster X0230

log Bayes Factor = 131.696

contains 7 variants

0.6187

Cluster X0141

log Bayes Factor = 742.063

contains 30 variants

0.6151

Cluster X0199

log Bayes Factor = 350.038

contains 3 variants

0.6138

Cluster X0182

log Bayes Factor = 91.4459

contains 4 variants

0.6062

Cluster X0231

log Bayes Factor = 82.3185

contains 5 variants

0.5840

Cluster X0110

log Bayes Factor = 721.325

contains 13 variants

0.5815

Cluster X0212

log Bayes Factor = 300.777

contains 10 variants

0.5775

Cluster X0189

log Bayes Factor = 149.681

contains 5 variants

0.5617

Cluster X0122

log Bayes Factor = 219.114

contains 9 variants

0.5606

Cluster X0139

log Bayes Factor = 304.555

contains 10 variants

0.5556

Cluster X0156

log Bayes Factor = 226.954

contains 9 variants

0.5555

Cluster X0061

log Bayes Factor = 293.105

contains 15 variants

0.5466

Cluster X0320

log Bayes Factor = 110.964

contains 6 variants

0.5432

Cluster X0188

log Bayes Factor = 222.629

contains 14 variants

0.5322

Cluster X0155

log Bayes Factor = 348.568

contains 12 variants

0.5225

Cluster X0080

log Bayes Factor = 455.123

contains 21 variants

0.5197

Cluster X0193

log Bayes Factor = 303.265

contains 16 variants

0.5196

Cluster X0227

log Bayes Factor = 249.287

contains 11 variants

0.5114

Cluster X0063

log Bayes Factor = 107.557

contains 5 variants

0.5057

Cluster X0243

log Bayes Factor = 104.974

contains 6 variants

0.4888

Cluster X0327

log Bayes Factor = 118.248

contains 3 variants

0.4859

Cluster X0004

log Bayes Factor = 32.8452

contains 2 variants

0.4508

Cluster X0018

log Bayes Factor = 430.611

contains 18 variants

0.4391

Cluster X0284

log Bayes Factor = 192.532

contains 9 variants

0.4224

Cluster X0238

log Bayes Factor = 97.9307

contains 4 variants

0.4178

Cluster X0147

log Bayes Factor = 133.509

contains 9 variants

0.4120

Cluster X0012

log Bayes Factor = 112.432

contains 5 variants

0.4075

Cluster X0118

log Bayes Factor = 91.1908

contains 5 variants

0.3815

Cluster X0220

log Bayes Factor = 142.284

contains 7 variants

0.3615

Cluster X0337

log Bayes Factor = 84.9395

contains 2 variants

0.3524

Cluster X0001

log Bayes Factor = 167.541

contains 7 variants

0.3096

Cluster X0219

log Bayes Factor = 230.324

contains 15 variants

0.3084

Cluster X0028

log Bayes Factor = 120.445

contains 7 variants

0.2988

Cluster X0209

log Bayes Factor = 214.798

contains 8 variants

0.2839

Cluster X0062

log Bayes Factor = 68.7461

contains 4 variants

0.2353

Cluster X0129

log Bayes Factor = 195.809

contains 7 variants

0.2244

Cluster X0163

log Bayes Factor = 122.554

contains 6 variants

0.2117

Cluster X0064

log Bayes Factor = 166.06

contains 10 variants

0.1791

Cluster X0275

log Bayes Factor = 219.726

contains 10 variants

0.1600

Cluster X0235

log Bayes Factor = 54.4898

contains 2 variants

0.1502

Cluster X0007

log Bayes Factor = 107.567

contains 7 variants

0.1195

Cluster X0240

log Bayes Factor = 104.862

contains 6 variants

0.0766

Cluster X0068

log Bayes Factor = 127.774

contains 6 variants

0.0746

Cluster X0225

log Bayes Factor = 36.4143

contains 3 variants

0.0696

Cluster X0160

log Bayes Factor = 99.5328

contains 9 variants

0.0665

Cluster X0194

log Bayes Factor = 189.9

contains 5 variants

0.0550

Cluster X0191

log Bayes Factor = 163.555

contains 8 variants

0.0535

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Diagnostic term associations

Hospitalization Episode Statistics (HES)

(posterior probability > 0.05)

(posterior probability > 0.05)

Hospitalization Episode Statistics (`HES`)